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K

Karen Blyth

Cancer Research UK Scotland Institute
H指数:56
被引数:1.2万

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Multiscale in vivo imaging of tumor evolution using a germline conditional triple-reporter mouse

利用种系条件三报告小鼠对肿瘤演化的多尺度活体成像

Nature Biotechnology
IF41.7
2026-07-150
OAAI
Ximena L. Raffo-Iraolagoitia; Abdullah Alyamani; Stephanie May; David Stevenson; Agata Mackintosh; Lynn McGarry; Jayanthi Anand; Dmitry Soloviev; Gavin Brown; Colin Nixon; Chrysa Kapeni; Maike De La Roche; Karen Blyth; Thomas Graham Bird; Douglas Strathdee; Scott K. Lyons; Gilbert Fruhwirth; Leo M. Carlin; David Y. Lewis
Targeting RUNX1 protects against diastolic dysfunction in a two-hit mouse model of heart failure with preserved ejection fraction

靶向RUNX1可保护两-hit小鼠模型中保留射血分数的心力衰竭免于心功能不全

Cardiovascular Research
IF13.3
2026-05-260
OA
Ali Ali Mohamed Elbassioni; Anmar A Raheem; Jian Song; Alexander S Johnston; Cara Trivett; Hong Lin; Haobo Zhang; Ashley Bradley; Erin Higgins; Cameron R Thomson; Leanne Mooney; Yen Chin Koay; Dylan O’Toole; Pawel Herzyk; Colin Nixon; Karen Blyth; Mark Hughes; John F O’Sullivan; Ninian N Lang; Colin Berry; Thomas Braun; Gabriele G Schiattarella; Mauro Giacca; Martin W McBride; Stuart A Nicklin; Ewan R Cameron; Christopher M Loughrey; Eilidh A MacDonald; null
AKT/mTOR as a targetable hub to overcome multimodal resistance to EGFR inhibitors in oesophageal squamous cell carcinoma

AKT/mTOR作为克服食管鳞状细胞癌对EGFR抑制剂的多模态耐药性的可靶向枢纽

British Journal of Cancer
IF6.8
2025-07-040
OAAI
Lindsay C. Spender; Dale M. Watt; Mark A. Baxter; Morven K. Shuttleworth; Kateah Walker; Alice R. Savage; Hollie A. Clements; Yury Kapelyukh; Susan E. Bray; Sharon I. King; C. Roland Wolf; Gareth J. Inman; Shaun V. Walsh; Karen Blyth; Russell D. Petty
Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells

组蛋白分子伴侣HIRA失活揭示了黑色素细胞前体正常胚胎发育与成体黑色素细胞干细胞维持之间的联系

AGING CELL
IF7.1
2025-05-140
OA
Jaber-Hijazi, F; Arnold, R; Swaminathan, K; Gilroy, K; Wenzel, AT; Lagnado, A; Kirschner, K; Robertson, N; Reid, C; Fullarton, N; Pawlikowski, J; Rai, TS; Baranyk, I; Shi, CH; Yip, KY; Blyth, K; Mesirov, JP; Harris, ML; Passos, JF; Machesky, LM; Adams, PD
Locking CBL TKBD in its native conformation presents a novel therapeutic opportunity in mutant CBL-dependent leukemia

将CBL TKBD锁定在其天然构象中，为突变依赖性CBL白血病提供了新的治疗机会。

Molecular Therapy
IF12
2025-05-050
OAAI
Syed Feroj Ahmed; Jayanthi Anand; Wei Zhang; Lori Buetow; Loveena Rishi; Louise Mitchell; Jonathan Bohlen; Sergio Lilla; Gary J. Sibbet; Colin Nixon; Amrita Patel; Karolina A. Majorek; Sara Zanivan; Jacinta C. Bustamante; Sachdev S. Sidhu; Karen Blyth; Danny T. Huang
IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors
EMBO JOURNAL
IF8.3
2024-05-300
OAAI
Wiesheu, Robert; Edwards, Sarah C.; Hedley, Ann; Hall, Holly; Tosolini, Marie; da Silva, Marcelo Gregorio Filho Fares; Sumaria, Nital; Castenmiller, Suzanne M.; Wardak, Leyma; Optaczy, Yasmin; Lynn, Amy; Hill, David G.; Hayes, Alan J.; Hay, Jodie; Kilbey, Anna; Shaw, Robin; Whyte, Declan; Walsh, Peter J.; Michie, Alison M.; Graham, Gerard J.; Manoharan, Anand; Halsey, Christina; Blyth, Karen; Wolkers, Monika C.; Miller, Crispin; Pennington, Daniel J.; Jones, Gareth W.; Fournie, Jean-Jacques; Bekiaris, Vasileios; Coffelt, Seth B.
Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma
NATURE CANCER
IF28.5
2024-01-2916
OAAI
Mahmood, Mahnoor; Liu, Eric Minwei; Shergold, Amy L.; Tolla, Elisabetta; Tait-Mulder, Jacqueline; Huerta-Uribe, Alejandro; Shokry, Engy; Young, Alex L.; Lilla, Sergio; Kim, Minsoo; Park, Tricia; Boscenco, Sonia; Manchon, Javier L.; Rodriguez-Antona, Cristina; Walters, Rowan C.; Springett, Roger J.; Blaza, James N.; Mitchell, Louise; Blyth, Karen; Zanivan, Sara; Sumpton, David; Roberts, Edward W.; Reznik, Ed; Gammage, Payam A.

研究方向

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C
Colin Nixon
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S
Susan Mason
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D
Dimitris Athineos
H 指数:34论文数:107被引数:8,308
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Ewan R. Cameron
H 指数:33论文数:89被引数:3,224
O
Owen J. Sansom
H 指数:113论文数:1,190被引数:5.1万
S
Sara Zanivan
H 指数:39论文数:212被引数:9,555
S
Stephen W. G. Tait
H 指数:61论文数:153被引数:3.5万
J
James C. Neil
H 指数:43论文数:121被引数:4,659
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Kirsteen J. Campbell
H 指数:26论文数:69被引数:3,790
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Sandeep Dhayade
H 指数:18论文数:38被引数:1,945