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Single-shot dendritic cell targeting SARS-CoV-2 vaccine candidate induces broad, durable and protective systemic and mucosal immunity in mice Cheang, Nicholas You Zhi; Tan, Kai Sen; Tan, Peck Szee; Purushotorma, Kiren; Yap, Wee Chee; Tullett, Kirsteen McInnes; Chua, Benson Yen Leong; Yeoh, Aileen Ying-Yan; Tan, Caris Qi Hui; Qian, Xinlei; Chen, Huixin; Tay, Douglas Jie Wen; Caminschi, Irina; Tan, Yee Joo; Macary, Paul Anthony; Tan, Chee Wah; Lahoud, Mireille Hanna; Alonso, Sylvie 分享 收藏
First-in-human study of ATR inhibitor IMP9064 monotherapy and in combination with PARP inhibitor senaparib in patients with advanced solid tumors Lin, C-C.; Schneider, R. E.; Gutierrez, M.; Shen, L.; Gao, B.; Chung, K.; Doroshow, D. B.; Millward, M.; Hsieh, C-Y.; Xu, C.; Cai, S. X.; Tian, Y. E.; Liu, L.; Shen, C.; Li, B.; Tan, Y.; Zhang, C.; Li, L.; Ma, M.; Chen, X. 分享 收藏
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The IDentif.AI-x pandemic readiness platform: Rapid prioritization of optimized COVID-19 combination therapy regimens IDentif.Ai-x大流行准备平台: 优化新型冠状病毒肺炎联合治疗方案的快速优先级 Blasiak, Agata; Truong, Anh T. L.; Remus, Alexandria; Hooi, Lissa; Seah, Shirley Gek Kheng; Wang, Peter; Chye, De Hoe; Lim, Angeline Pei Chiew; Ng, Kim Tien; Teo, Swee Teng; Tan, Yee-Joo; Allen, David Michael; Chai, Louis Yi Ann; Chng, Wee Joo; Lin, Raymond T. P.; Lye, David C. B.; Wong, John Eu-Li; Tan, Gek-Yen Gladys; Chan, Conrad En Zuo; Chow, Edward Kai-Hua; Ho, Dean 分享 收藏
Polymersomes as Stable Nanocarriers for a Highly Immunogenic and Durable SARS-CoV-2 Spike Protein Subunit Vaccine 聚合物体作为稳定的纳米载体，用于高免疫原性和持久的SARS-CoV-2刺突蛋白亚单位疫苗 Lam, Jian Hang; Khan, Amit K.; Cornell, Thomas A.; Chia, Teck Wan; Dress, Regine J.; Yeow, Wen Wang William; Mohd-Ismail, Nur Khairiah; Venkataraman, Shrinivas; Ng, Kim Tien; Tan, Yee-Joo; Anderson, Danielle E.; Ginhoux, Florent; Nallani, Madhavan 分享 收藏
Comparative Transcriptomic and Molecular Pathway Analyses of HL-CZ Human Pro-Monocytic Cells Expressing SARS-CoV-2 Spike S1, S2, NP, NSP15 and NSP16 Genes Sharma, Anshika; Ong, Joe W.; Loke, Mun Fai; Chua, Eng Guan; Lee, Joseph J.; Choi, Hyung Won; Tan, Yee Joo; Lal, Sunil K.; Chow, Vincent T. 分享 收藏
Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection 无症状SARS-CoV-2感染的高功能病毒特异性细胞免疫反应 Le Bert, Nina; Clapham, Hannah E.; Tan, Anthony T.; Chia, Wan Ni; Tham, Christine Y. L.; Lim, Jane M.; Kunasegaran, Kamini; Tan, Linda Wei Lin; Dutertre, Charles-Antoine; Shankar, Nivedita; Lim, Joey M. E.; Sun, Louisa Jin; Zahari, Marina; Tun, Zaw Myo; Kumar, Vishakha; Lim, Beng Lee; Lim, Siew Hoon; Chia, Adeline; Tan, Yee-Joo; Tambyah, Paul Anantharajah; Kalimuddin, Shirin; Lye, David; Low, Jenny G. H.; Wang, Lin-Fa; Wan, Wei Yee; Hsu, Li Yang; Bertoletti, Antonio; Tam, Clarence C. 分享 收藏
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JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality 抑制JAK可降低SARS-CoV-2肝脏感染性并调节炎症反应，从而降低发病率和死亡率 Stebbing, Justin; Nievas, Gines Sanchez; Falcone, Marco; Youhanna, Sonia; Richardson, Peter; Ottaviani, Silvia; Shen, Joanne X.; Sommerauer, Christian; Tiseo, Giusy; Ghiadoni, Lorenzo; Virdis, Agostino; Monzani, Fabio; Rizos, Luis Romero; Forfori, Francesco; Avendano-Cespedes, Almudena; De Marco, Salvatore; Carrozzi, Laura; Lena, Fabio; Sanchez-Jurado, Pedro Manuel; Lacerenza, Leonardo Gianluca; Cesira, Nencioni; Caldevilla-Bernardo, David; Perrella, Antonio; Niccoli, Laura; Mendez, Lourdes Saez; Matarrese, Daniela; Goletti, Delia; Tan, Yee-Joo; Monteil, Vanessa; Dranitsaris, George; Cantini, Fabrizio; Farcomeni, Alessio; Dutta, Shuchismita; Burley, Stephen K.; Zhang, Haibo; Pistello, Mauro; Li, William; Romero, Marta Mas; Pretel, Fernando Andres; Simon-Talero, Rafaela Sanchez; Garcia-Molina, Rafael; Kutter, Claudia; Felce, James H.; Nizami, Zehra F.; Miklosi, Andras G.; Penninger, Josef M.; Menichetti, Francesco; Mirazimi, Ali; Abizanda, Pedro; Lauschke, Volker M. 分享 收藏
L226Q Mutation on Influenza H7N9 Virus Hemagglutinin Increases Receptor-Binding Avidity and Leads to Biased Antigenicity Evaluation H7N9流感病毒血凝素的L226Q突变增加受体结合亲和力并导致抗原性评估偏倚 Wang, Yang; Lv, Yunhua; Niu, Xuefeng; Dong, Ji; Feng, Pei; Li, Qinming; Xu, Wei; Li, Jiashun; Li, Chufang; Li, Jiahui; Luo, Jia; Li, Zhixia; Liu, Yichu; Tan, Yee-Joo; Pan, Weiqi; Chen, Ling 分享 收藏
A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2-spike protein-protein interaction 基于抗体介导的ACE2-spike蛋白-蛋白相互作用阻断的SARS-CoV-2替代病毒中和试验 Tan, Chee Wah; Chia, Wan Ni; Qin, Xijian; Liu, Pei; Chen, Mark I-C; Tiu, Charles; Hu, Zhiliang; Chen, Vivian Chih-Wei; Young, Barnaby E.; Sia, Wan Rong; Tan, Yee-Joo; Foo, Randy; Yi, Yongxiang; Lye, David C.; Anderson, Danielle E.; Wang, Lin-Fa 分享 收藏
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