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PREDICTING EARLY DEATH IN DIFFUSE MIDLINE GLIOMA Moloney, Sam; Carruthers, Vickyanne; Davis, Melissa J.; Bhuva, Dharmesh D.; Mignone, Cristina; Singh, Susan; Gardiner, Rebecca E.; Valvi, Santosh; Eisenstat, David D.; Hansford, Jordan R. 分享 收藏
Spatial omics techniques and data analysis for cancer immunotherapy applications Zhang, Yue; Lee, Ren Yuan; Tan, Chin Wee; Guo, Xue; Yim, Willa W-Y; Lim, Jeffrey C. T.; Wee, Felicia Y. T.; Yang, Wu; Kharbanda, Malvika; Lee, Jia-Ying J.; Ngo, Nye Thane; Leow, Wei Qiang; Loo, Lit-Hsin; Lim, Tony K. H.; Sobota, Radoslaw M.; Lau, Mai Chan; Davis, Melissa J.; Yeong, Joe 分享 收藏
Library size confounds biology in spatial transcriptomics data Bhuva, Dharmesh D.; Tan, Chin Wee; Salim, Agus; Marceaux, Claire; Pickering, Marie A.; Chen, Jinjin; Kharbanda, Malvika; Jin, Xinyi; Liu, Ning; Feher, Kristen; Putri, Givanna; Tilley, Wayne D.; Hickey, Theresa E.; Asselin-Labat, Marie-Liesse; Phipson, Belinda; Davis, Melissa J. 分享 收藏
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ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia Behrens, Kira; Brajanovski, Natalie; Xu, Zhen; Viney, Elizabeth M.; Dirago, Ladina; Hediyeh-Zadeh, Soroor; Davis, Melissa J.; Pearson, Richard B.; Sanij, Elaine; Alexander, Warren S.; Ng, Ashley P. 分享 收藏
In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection Tan, Chin Wee; Chen, Jinjin; Liu, Ning; Bhuva, Dharmesh D.; Blick, Tony; Monkman, James; Cooper, Caroline; Kharbanda, Malvika; Feher, Kristen; Phipson, Belinda; Killingbeck, Emily E.; Pan, Liuliu; Kim, Youngmi; Liang, Yan; Nam, Andy; Leon, Michael; Souza-Fonseca-Guimaraes, Paulo; Nagashima, Seigo; Martins, Ana Paula Camargo; Machado-Souza, Cleber; de Noronha, Lucia; Tang, Benjamin; Short, Kirsty; Fraser, John; Belz, Gabrielle T.; Souza-Fonseca-Guimaraes, Fernando; Kulasinghe, Arutha; Davis, Melissa J. 分享 收藏
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development Goh, Wilford; Sudholz, Harrison; Foroutan, Momeneh; Scheer, Sebastian; Pfefferle, Aline; Delconte, Rebecca B.; Meng, Xiangpeng; Shen, Zihan; Hennessey, Robert; Kong, Isabella Y.; Schuster, Iona S.; Andoniou, Christopher E.; Davis, Melissa J.; Hediyeh-Zadeh, Soroor; Souza-Fonseca-Guimaraes, Fernando; Parish, Ian A.; Beavis, Paul; Thiele, Daniel; Chopin, Michael; Degli-Esposti, Mariapia A.; Cursons, Joe; Kallies, Axel; Rautela, Jai; Nutt, Stephen L.; Huntington, Nicholas D. 分享 收藏
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Implementation of DNA Methylation Array Profiling in Pediatric Central Nervous System Tumors The AIM BRAIN Project: An Australian and New Zealand Children's Haematology/Oncology Group Study AIM BRAIN项目: 澳大利亚和新西兰儿童血液学/肿瘤学小组研究 White, Christine L.; Kinross, Kathryn M.; Moore, Molly K.; Rasouli, Elnaz; Strong, Robyn; Jones, Janelle M.; Cain, Jason E.; Sturm, Dominik; Sahm, Felix; Jones, David T. W.; Pfister, Stefan M.; Robertson, Thomas; D'Arcy, Colleen; Rodriguez, Michael L.; Dyke, Jason M.; Junckerstorff, Reimar; Bhuva, Dharmesh D.; Davis, Melissa J.; Wood, Paul; Hassall, Tim; Ziegler, David S.; Kellie, Stewart; McCowage, Geoffrey; Alvaro, Frank; Kirby, Maria; Heath, John A.; Tsui, Karen; Dodgshun, Andrew; Eisenstat, David D.; Khuong-Quang, Dong-Anh; Wall, Meaghan; Algar, Elizabeth M.; Gottardo, Nicholas G.; Hansford, Jordan R. 分享 收藏
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer 发现一种高效,选择性,口服生物利用度的KAT6A/B组蛋白乙酰转移酶抑制剂,对KAT6A-high ER乳腺癌有效 Sharma, Shikhar; Chung, Chi-Yeh; Uryu, Sean; Petrovic, Jelena; Cao, Joan; Rickard, Amanda; Nady, Nataliya; Greasley, Samantha; Johnson, Eric; Brodsky, Oleg; Khan, Showkhin; Wang, Hui; Wang, Zhenxiong; Zhang, Yong; Tsaparikos, Konstantinos; Chen, Lei; Mazurek, Anthony; Lapek, John; Kung, Pei-Pei; Sutton, Scott; Richardson, Paul F.; Greenwald, Eric C.; Yamazaki, Shinji; Jones, Rhys; Maegley, Karen A.; Bingham, Patrick; Lam, Hieu; Stupple, Alexandra E.; Kamal, Aileen; Chueh, Anderly; Cuzzupe, Anthony; Morrow, Benjamin J.; Ren, Bin; Carrasco-Pozo, Catalina; Tan, Chin Wee; Bhuva, Dharmesh D.; Allan, Elizabeth; Surgenor, Elliot; Vaillant, Francois; Pehlivanoglu, Havva; Falk, Hendrik; Whittle, James R.; Newman, Janet; Cursons, Joseph; Doherty, Judy P.; White, Karen L.; Macpherson, Laura; Devlin, Mark; Dennis, Matthew L.; Hattarki, Meghan K.; De Silva, Melanie; Camerino, Michelle A.; Butler, Miriam S.; Dolezal, Olan; Pilling, Patricia; Foitzik, Richard; Stupple, Paul A.; Lagiakos, H. Rachel; Walker, Scott R.; Hediyeh-Zadeh, Soroor; Nuttall, Stewart; Spall, Sukhdeep; Charman, Susan A.; Connor, Theresa; Peat, Thomas S.; Avery, Vicky M.; Bozikis, Ylva E.; Yang, Yuqing; Zhang, Ming; Monahan, Brendon J.; Voss, Anne K.; Street, Ian P.; Dawson, Sarah-Jane; Dawson, Mark A.; Lindeman, Geoffrey J.; Davis, Melissa J.; Visvader, Jane E.; Paul, Thomas A. 分享 收藏
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Single-cell RNA sequencing captures patient-level heterogeneity and associated molecular phenotypes in breast cancer pleural effusions 单细胞RNA测序可捕获乳腺癌胸腔积液中患者水平的异质性和相关分子表型 Whitfield, Holly J.; Berthelet, Jean; Mangiola, Stefano; Bell, Caroline; Anderson, Robin L.; Pal, Bhupinder; Yeo, Belinda; Papenfuss, Anthony T.; Merino, Delphine; Davis, Melissa J. 分享 收藏
Basonuclin-2 regulates extracellular matrix production and degradation Basonuclin-2调节细胞外基质的产生和降解 Orang, Ayla; Dredge, B. Kate; Liu, Chi Yau; Bracken, Julie M.; Chen, Chun-Hsien; Sourdin, Laura; Whitfield, Holly J.; Lumb, Rachael; Boyle, Sarah; Davis, Melissa J.; Samuel, Michael S.; Gregory, Philip A.; Khew-Goodall, Yeesim; Goodall, Gregory J.; Pillman, Katherine A.; Bracken, Cameron P. 分享 收藏
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Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer 在三阴性乳腺癌中使用CRISPR/dCas9平台的间充质上皮状态的合成表观遗传重编程 Waryah, Charlene; Cursons, Joseph; Foroutan, Momeneh; Pflueger, Christian; Wang, Edina; Molania, Ramyar; Sorolla, Anabel; Wallis, Christopher; Moses, Colette; Glas, Irina; Magalhaes, Leandro; Thompson, Erik W.; Fearnley, Liam G.; Chaffer, Christine L.; Davis, Melissa; Papenfuss, Anthony T.; Redfern, Andrew; Lister, Ryan; Esteller, Manel; Blancafort, Pilar 分享 收藏
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Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition Vo, Tuan; Balderson, Brad; Jones, Kahli; Ni, Guiyan; Crawford, Joanna; Millar, Amanda; Tolson, Elissa; Singleton, Matthew; Kojic, Marija; Robertson, Thomas; Walters, Shaun; Mulay, Onkar; Bhuva, Dharmesh D.; Davis, Melissa J.; Wainwright, Brandon J.; Nguyen, Quan; Genovesi, Laura A. 分享 收藏
Spatial profiling of the tumor microenvironment in head and neck cancer identifies immune checkpoints and proteins involved in cell death signaling biomarkers of immunotherapy response Sadeghirad, Habib; Liu, Ning; Monkman, James; Tan, Chin Wee; Cooper, Caroline; Caldera, Jeni; Church, Sarah; Schneider, Fabian; Mansfield, James Robert; O'Byrne, Ken; Davis, Melissa; Hughes, Brett; Kulasinghe, Arutha 分享 收藏