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B

Brandyn Castro

university of chicago
H指数:18
被引数:1,921

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Targeting TGFβ-mediated B cell suppression enhances anti-PD-1 efficacy in glioblastoma

靶向TGFβ介导的B细胞抑制可增强胶质母细胞瘤中抗PD-1的疗效

NEURO-ONCOLOGY
IF13.4
2025-11-010
OAAI
Hou, David; Wang, Si; Castro, Brandyn A.; Katz, Joshua L.; Dapash, Mark; Arrieta, Victor A.; Vazquez-Cervantes, Gustavo, I; Wan, Hanxiao; Billingham, Leah K.; Du, Rebecca; Murphy, Alina R.; Lopez-Rosas, Aurora; Han, Yu; Patel, Ronit, V; Chia, Tzu-Yi; Dmello, Crismita C.; Zhang, Peng; Sheppard, Dean; Sonabend, Adam M.; Miska, Jason M.; Lesniak, Maciej S.; Heiland, Dieter Henrik; Lee-Chang, Catalina
Dual aVß8 Integrin and PD-1 Blockade Overcomes TGFβ-Mediated B-Cell Suppression to Enhance Anti-Tumor Immunity

双aVß8整合素和PD-1阻断克服TGFβ介导的B细胞抑制以增强抗肿瘤免疫

NEURO-ONCOLOGY
IF13.4
2025-06-011
PRE
Hou, David; Wang, Si; Castro, Brandyn A.; Katz, Joshua L.; Dapash, Mark; Arrieta, Victor A.; Vazquez-Cervantes, Gustavo, I; Wan, Hanxiao; Billingham, Leah K.; Du, Rebecca; Murphy, Alina R.; Lopez-Rosas, Aurora; Han, Yu; Patel, Ronit, V; Chia, Tzu-Yi; Dmello, Crismita C.; Zhang, Peng; Sheppard, Dean; Sonabend, Adam M.; Miska, Jason M.; Lesniak, Maciej S.; Heiland, Dieter Henrik; Lee-Chang, Catalina
Endothelial response to blood-brain barrier disruption in the human brain
JCI INSIGHT
IF6.1
2024-12-260
OA
Gould, Andrew; Luan, Yu; Hou, Ye; Korobova, Farida, V; Chen, Li; Arrieta, Victor A.; Amidei, Christina; Ward, Rachel; Gomez, Cristal; Castro, Brandyn; Habashy, Karl; Zhang, Daniel; Youngblood, Mark; Dmello, Crismita; Bebawy, John; Bouchoux, Guillaume; Stupp, Roger; Canney, Michael; Yue, Feng; Iruela-Arispe, M. Luisa; Sonabend, Adam M.
B-CELL BASED THERAPY (BVAX) PRODUCES ANTIBODIES TO SUPPRESS GLIOBLASTOMA TUMOR MIGRATION AND INVASION
NEURO-ONCOLOGY
IF13.4
2024-11-110
PRE
Katz, Joshua; Castro, Brandyn; Wang, Si; Arrieta, Victor; Najem, Hinda; Vazquez-Cervantes, Gustavo Ignacio; Olson, Ian; Hou, David; Dapash, Mark; Wan, Hanxiao; Rashidi, Aida; Arjmandi, Tarlan; Shaikh, Zainab; Jones, Grace; Platanias, Leonidas; Mccortney, Kathleen; Horbinski, Craig; Stupp, Roger; Zhang, Peng; Ahmed, Atique; Sonabend, Adam; Heimberger, Amy; Lesniak, Maciej; Riviere-Cazaux, Cecile; Burns, Terry; Miska, Jason; Fischietti, Mariafausta; Lee-Chang, Catalina
B cell-based therapy produces antibodies that inhibit glioblastoma growth
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-08-290
OAAI
Wang, Si; Castro, Brandyn A.; Katz, Joshua L.; Arrieta, Victor; Najem, Hinda; Vazquez-Cervantes, Gustavo I.; Wan, Hanxiao; Olson, Ian E.; Hou, David; Dapash, Mark; Billingham, Leah K.; Chia, Tzu-yi; Wei, Chao; Rashidi, Aida; Platanias, Leonidas C.; Mccortney, Kathleen; Horbinski, Craig M.; Stupp, Roger; Zhang, Peng; Ahmed, Atique U.; Sonabend, Adam M.; Heimberger, Amy B.; Lesniak, Maciej S.; Riviere-Cazaux, Cecile; Burns, Terry; Miska, Jason; Fischietti, Mariafausta; Lee-Chang, Catalina
Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas
NEURO-ONCOLOGY
IF13.4
2024-07-191
PRE
Kim, Kwang-Soo; Habashy, Karl; Gould, Andrew; Zhao, Junfei; Najem, Hinda; Amidei, Christina; Saganty, Ruth; Arrieta, Victor A.; Dmello, Crismita; Chen, Li; Zhang, Daniel Y.; Castro, Brandyn; Billingham, Leah; Levey, Daniel; Huber, Olivia; Marques, Marilyn; Savitsky, David A.; Morin, Benjamin M.; Muzzio, Miguel; Canney, Michael; Horbinski, Craig; Zhang, Peng; Miska, Jason; Padney, Surya; Zhang, Bin; Rabadan, Raul; Phillips, Joanna J.; Butowski, Nicholas; Heimberger, Amy B.; Hu, Jian; Stupp, Roger; Chand, Dhan; Lee-Chang, Catalina; Sonabend, Adam M.
Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas
NATURE COMMUNICATIONS
IF15.7
2024-06-0612
OAAI
Arrieta, Victor A.; Gould, Andrew; Kim, Kwang-Soo; Habashy, Karl J.; Dmello, Crismita; Vazquez-Cervantes, Gustavo I.; Palacin-Aliana, Irina; McManus, Graysen; Amidei, Christina; Gomez, Cristal; Dhiantravan, Silpol; Chen, Li; Zhang, Daniel Y.; Saganty, Ruth; Cholak, Meghan E.; Pandey, Surya; Mccord, Matthew; Mccortney, Kathleen; Castro, Brandyn; Ward, Rachel; Muzzio, Miguel; Bouchoux, Guillaume; Desseaux, Carole; Canney, Michael; Carpentier, Alexandre; Zhang, Bin; Miska, Jason M.; Lesniak, Maciej S.; Horbinski, Craig M.; Lukas, Rimas V.; Stupp, Roger; Lee-Chang, Catalina; Sonabend, Adam M.
Antigen-presenting B cells promote TCF-1+ PD1- stem-like CD8+ T-cell proliferation in glioblastoma
FRONTIERS IN IMMUNOLOGY
IF5.9
2024-01-105
OAAI
Hou, David; Wan, Hanxiao; Katz, Joshua L.; Wang, Si; Castro, Brandyn A.; Vazquez-Cervantes, Gustavo I.; Arrieta, Victor A.; Dhiantravan, Silpol; Najem, Hinda; Rashidi, Aida; Chia, Tzu-yi; Arjmandi, Tarlan; Collado, Jimena; Billingham, Leah; Lopez-Rosas, Aurora; Han, Yu; Sonabend, Adam M.; Heimberger, Amy B.; Zhang, Peng; Miska, Jason; Lee-Chang, Catalina
Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth
CELL METABOLISM
IF30.9
2024-01-0111
PRE
Rashidi, Aida; Billingham, Leah K.; Zolp, Andrew; Chia, Tzu-yi; Silvers, Caylee; Katz, Joshua L.; Park, Cheol H.; Delay, Suzi; Boland, Lauren; Geng, Yuheng; Markwell, Steven M.; Dmello, Crismita; Arrieta, Victor A.; Zilinger, Kaylee; Jacob, Irene M.; Lopez-Rosas, Aurora; Hou, David; Castro, Brandyn; Steffens, Alicia M.; McCortney, Kathleen; Walshon, Jordain P.; Flowers, Mariah S.; Lin, Hanchen; Wang, Hanxiang; Zhao, Junfei; Sonabend, Adam; Zhang, Peng; Ahmed, Atique U.; Brat, Daniel J.; Heiland, Dieter H.; Lee-Chang, Catalina; Lesniak, Maciej S.; Chandel, Navdeep S.; Miska, Jason
Combination of tucatinib and neural stem cells secreting anti-HER2 antibody prolongs survival of mice with metastatic brain cancer
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-12-309
OAAI
Cordero, Alex; Ramsey, Matthew D.; Kanojia, Deepak; Fares, Jawad; Petrosyan, Edgar; Schwartz, Charles W.; Burga, Rachel; Zhang, Peng; Rashidi, Aida; Castro, Brandyn; Xiao, Ting; Lee-Chang, Catalina; Miska, Jason; Balyasnikova, Irina, V; Ahmed, Atique U.; Lesniak, Maciej S.
TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma
FRONTIERS IN IMMUNOLOGY
IF5.9
2021-05-0745
OAAI
Raphael, Itay; Kumar, Rajeev; McCarl, Lauren H.; Shoger, Karsen; Wang, Lin; Sandlesh, Poorva; Sneiderman, Chaim T.; Allen, Jordan; Zhai, Shuyan; Campagna, Marissa Lynn; Foster, Alexandra; Bruno, Tullia C.; Agnihotri, Sameer; Hu, Baoli; Castro, Brandyn A.; Lieberman, Frank S.; Broniscer, Alberto; Diaz, Aaron A.; Amankulor, Nduka M.; Rajasundaram, Dhivyaa; Pollack, Ian F.; Kohanbash, Gary
Identifying genomic drivers of lung adenocarcinoma brain metastases
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Nayyar, Naema; Shih, David J.; Bihun, Ivanna; Dagogo-Jack, Ibiayi; Gill, Corey M.; Aquilanti, Elisa; Bertalan, Mia; Kaplan, Alexander; D'Andrea, Megan R.; Chukwueke, Ugonma; Alvarez-Breckenridge, Christopher; Lastrapes, Matthew; Kuter, Ben; Strickland, Matthew R.; Martinez-Gutierrez, Juan Carlos; Nagabhushan, Deepika; De Sauvage, Magali; White, Michael D.; Castro, Brandyn A.; Hoang, Kaitlin; Paek, Sun Ha; Park, Sun Hye; Martinez-Lage, Maria; Berghoff, Anna S.; Merrill, Parker; Gerstner, Elizabeth R.; Batchelor, Tracy T.; Frosch, Matthew P.; Frazier, Ryan P.; Borger, Darrell R.; Iafrate, A. John; Santagata, Sandro; Preusser, Matthias; Cahill, Daniel P.; Carter, Scott L.; Brastianos, Priscilla K.
Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma
NATURE GENETICS
IF31.8
2020-03-23190
OAAI
Shih, David J. H.; Nayyar, Naema; Bihun, Ivanna; Dagogo-Jack, Ibiayi; Gill, Corey M.; Aquilanti, Elisa; Bertalan, Mia; Kaplan, Alexander; D'Andrea, Megan R.; Chukwueke, Ugonma; Ippen, Franziska Maria; Alvarez-Breckenridge, Christopher; Camarda, Nicholas D.; Lastrapes, Matthew; McCabe, Devin; Kuter, Ben; Kaufman, Benjamin; Strickland, Matthew R.; Martinez-Gutierrez, Juan Carlos; Nagabhushan, Deepika; De Sauvage, Magali; White, Michael D.; Castro, Brandyn A.; Hoang, Kaitlin; Kaneb, Andrew; Batchelor, Emily D.; Paek, Sun Ha; Park, Sun Hye; Martinez-Lage, Maria; Berghoff, Anna S.; Merrill, Parker; Gerstner, Elizabeth R.; Batchelor, Tracy T.; Frosch, Matthew P.; Frazier, Ryan P.; Borger, Darrell R.; Iafrate, A. John; Johnson, Bruce E.; Santagata, Sandro; Preusser, Matthias; Cahill, Daniel P.; Carter, Scott L.; Brastianos, Priscilla K.

研究方向

暂未获取到该数据
C
Catalina Lee-Chang
H 指数:29论文数:215被引数:3,535
J
Jason Miska
H 指数:31论文数:206被引数:4,347
M
Maciej S. Lesniak
H 指数:70论文数:554被引数:1.7万
A
Adam M. Sonabend
H 指数:42论文数:318被引数:6,370
V
Víctor A. Arrieta
H 指数:18论文数:176被引数:1,644
D
David Hou
H 指数:13论文数:50被引数:913
C
Crismita Dmello
H 指数:18论文数:165被引数:1,923
A
Aida Rashidi
H 指数:20论文数:58被引数:1,895
A
Aurora Lopez‐Rosas
H 指数:21论文数:52被引数:2,018
R
Roger Stupp
H 指数:114论文数:841被引数:9.1万