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Filemon S. Dela Cruz

Memorial Sloan Kettering Cancer Center

25H指数
278论文数
3.0K被引数
收录论文 48
发表时间
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Single-cell protein activity analysis reveals aberrant myogenesis and IGF2-PI3K pathway dependencies in MYOD1-mutant rhabdomyosarcoma单细胞蛋白质活性分析揭示了MYOD1突变型横纹肌肉瘤中异常的肌发生以及IGF2-PI3K通路的依赖性。
errScience Advances
IF12.5
err2026-02-27
err0
errOAAI
errJosephine K. Dermawan; Fabio Vanoli; Henry Traux de Wardi; Jonathan N. Levi; Glorymar Ibanez Sanchez; Armaan Siddiquee; Samantha Brosius; Daoqi You; Franck Tirode; Patricia Sung; Marie Karanian; Daniel Pissaloux; Leonard H. Wexler; Andrew Kung; Alice Soragni; Filemon S. Dela Cruz; Jovana Pavisic; Cristina R. Antonescu
err分享
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Epigenetic targeting of PGBD5-dependent DNA damage in SMARCB1-deficient sarcomas表观遗传靶向SMARCB1缺乏性肉瘤中PGBD5依赖性的DNA损伤
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-10-15
err2
errOAAI
errKazansky, Yaniv; Mueller, Helen S.; Cameron, Daniel; Demarest, Phillip; Zaffaroni, Nadia; Arrighetti, Noemi; Zuco, Valentina; Mundi, Prabhjot S.; Kuwahara, Yasumichi; Somwar, Romel; Qu, Rui; Califano, Andrea; De Stanchina, Elisa; Dela Cruz, Filemon S.; Kung, Andrew L.; Gounder, Mrinal M.; Kentsis, Alex
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Author Correction: Clonal evolution during metastatic spread in high-risk neuroblastoma作者更正：高危神经母细胞瘤转移扩散过程中的克隆进化
errNature Genetics
IF0
err2025-08-05
err0
PREAI
errGunes Gundem; Max F. Levine; Stephen S. Roberts; Irene Y. Cheung; Juan S. Medina-Martínez; Yi Feng; Juan E. Arango-Ossa; Loic Chadoutaud; Mathieu Rita; Georgios Asimomitis; Joe Zhou; Daoqi You; Nancy Bouvier; Barbara Spitzer; David B. Solit; Filemon Dela Cruz; Michael P. LaQuaglia; Brian H. Kushner; Shakeel Modak; Neerav Shukla; Christine A. Iacobuzio-Donahue; Andrew L. Kung; Nai-Kong V. Cheung; Elli Papaemmanuil
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Prioritization of novel agents for further investigation in pediatric non-rhabdomyosarcoma soft tissue sarcomas: A report from the Children’s Oncology Group新型药物在儿童非横纹肌肉瘤软组织肉瘤中的优先级排序及进一步研究的报告：来自儿童肿瘤组的报告
errEuropean Journal of Cancer
IF7.1
err2025-07-06
err0
PREAI
errJacquelyn N. Crane; David P. Douglass; Sapna Oberoi; Natalie B. Collins; Ajay Gupta; Jonathan L. Metts; Viswatej Avutu; Filemon S. Dela Cruz; Jessica L. Davis; Noah C. Federman; Susan M. Hiniker; Theodore W. Laetsch; Corinne M. Linardic; Fariba Navid; Raya Saab; David S. Shulman; Jack F. Shern; Alice Soragni; Elizabeth A. Stewart; Stephanie Terezakis; Brenda J. Weigel; Aaron R. Weiss
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err收藏
A Bayesian active learning platform for scalable combination drug screens一种用于可扩展联合药物筛选的贝叶斯主动学习平台
errNATURE COMMUNICATIONS
IF15.7
err2025-01-02
err1
errOAAI
errTosh, Christopher; Tec, Mauricio; White, Jessica B.; Quinn, Jeffrey F.; Sanchez, Glorymar Ibanez; Calder, Paul; Kung, Andrew L.; Dela Cruz, Filemon S.
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Lessons learned from 20 years of preclinical testing in pediatric cancers从20年的儿科癌症临床前测试中吸取的经验教训
errPHARMACOLOGY & THERAPEUTICS
IF12.5
err2024-12-01
err0
PREAI
errSmith, Malcolm A.; Houghton, Peter J.; Lock, Richard B.; Maris, John M.; Gorlick, Richard; Kurmasheva, Raushan T.; Li, Xiao-Nan; Teicher, Beverly A.; Chuang, Jeffrey H.; Cruz, Filemon S. Dela; Dyer, Michael A.; Kung, Andrew L.; Lloyd, Michael W.; Mosse, Yael P.; Stearns, Timothy M.; Stewart, Elizabeth A.; Bult, Carol J.; Erickson, Stephen W.
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Roadmap for the next generation of Children's Oncology Group rhabdomyosarcoma trials
errCANCER
IF5.1
err2024-06-28
err0
PREAI
errMetts, Jonathan L.; Aye, Jamie M.; Crane, Jacquelyn N.; Oberoi, Sapna; Balis, Frank M.; Bhatia, Smita; Bona, Kira; Carleton, Bruce; Dasgupta, Roshni; Dela Cruz, Filemon S.; Greenzang, Katie A.; Kaufman, Jonathan L.; Linardic, Corinne M.; Parsons, Susan K.; Robertson-Tessi, Mark; Rudzinski, Erin R.; Soragni, Alice; Stewart, Elizabeth; Weigel, Brenda J.; Wolden, Suzanne L.; Weiss, Aaron R.; Venkatramani, Rajkumar; Heske, Christine M.
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Overcoming Clinical Resistance to EZH2 Inhibition Using Rational Epigenetic Combination Therapy
errCANCER DISCOVERY
IF33.3
err2024-06-03
err4
errOAAI
errKazansky, Yaniv; Cameron, Daniel; Mueller, Helen S.; Demarest, Phillip; Zaffaroni, Nadia; Arrighetti, Noemi; Zuco, Valentina; Kuwahara, Yasumichi; Somwar, Romel; Ladanyi, Marc; Qu, Rui; de Stanchina, Elisa; Dela Cruz, Filemon S.; Kung, Andrew L.; Gounder, Mrinal M.; Kentsis, Alex
err分享
err收藏
A systems biology approach for identifying targetable vulnerabilities in Ewing sarcoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errDela Cruz, Filemon S.; Mundi, Prabhjot S.; Siddiquee, Armaan; Guillan, Kristina; You, Daoqi; Sanchez, Glorymar Ibanez; Ndengu, Andoyo; Califano, Andrea; Kung, Andrew L.
err分享
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BATCHIE: An active learning platform for scalable combination drug screens
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errTosh, Christopher; Tec, Mauricio; White, Jessica; Quinn, Jeffrey F.; Sanchez, Glorymar Ibanez; Calder, Paul; Kung, Andrew L.; Dela Cruz, Filemon S.; Tansey, Wesley
err分享
err收藏
Evolution of clinically relevant variants in advanced pediatric sarcomas
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errComeau, Hannah Y.; De La Vega, Lorena Lazo; Church, Alanna J.; Maese, Luke D.; Pinto, Navin; Macy, Margaret E.; Applebaum, Mark A.; Sabnis, Amit J.; Kim, AeRang; Colace, Susan I.; Dela Cruz, Filemon; DuBois, Steven G.; Collins, Natalie B.; Janeway, Katherine A.
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Single-cell inference and validation of heterogeneous drug sensitivity in cholangiocarcinoma reveals dacinostat as novel therapeutic candidate
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errObradovic, Aleksandar; Tomassoni, Lorenzo; Yu, Daoqi; Drake, Charles G.; Dela Cruz, FIlemon; Kung, Andrew; Califano, Andrea
err分享
err收藏
Identification and pharmacological targeting of treatment-resistant, stem-like breast cancer cells for combination therapy
errCANCER RESEARCH
IF16.6
err2024-02-01
err1
PREAI
errWorley, Jeremy; Noh, Heeju; You, Daoqi; Turunen, Mikko M.; Ding, Hongxu; Paull, Evan; Griffin, Aaron T.; Grunn, Adina; Guillan, Kristina; Bush, Erin C.; Brosius, Samantha J.; Mundi, Prabhjot S.; Sims, Peter; Dalerba, Piero; Dela Cruz, Filemon S.; Kung, Andrew L.; Califano, Andrea
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SMARCAL1 is a novel candidate therapeutic target for ALT-positive osteosarcoma
errCANCER RESEARCH
IF16.6
err2024-01-09
err0
PREAI
errTaglialatela, Angelo; Chen, Xiao; Khan, Zahra Fatema; Dela Cruz, Filemon; Shivi, Dua; Oswald, Dillon; Benura, Azeroglu; Denchi, Eros Lazzerini; Jaewon, Min; Kung, Andrew L.; Ciccia, Alberto
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Dynamic network curvature analysis of gene expression reveals novel potential therapeutic targets in sarcoma
errSCIENTIFIC REPORTS
IF3.9
err2024-01-04
err2
errOAAI
errElkin, Rena; Oh, Jung Hun; Cruz, Filemon Dela; Norton, Larry; Deasy, Joseph O.; Kung, Andrew L.; Tannenbaum, Allen R.
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err收藏
A phase 1 dose-escalation study of PRT2527, a cyclin-dependent kinase 9 (CDK9) inhibitor, in adult patients with advanced solid tumors: An updated analysis
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2023-12-01
err0
PREAI
errPatel, Manish R.; Basu-Mallick, Astrayee; Dela Cruz, Filemon; Orr, Douglas; Spira, Alex; Sonpavde, Guru P.; Ghatalia, Pooja; Lihou, Christine; Sharma, Neelesh; Scherle, Peggy; Sun, William; Sahasranaman, Sri; Henry, Jason T.
err分享
err收藏
Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma
errCANCER RESEARCH
IF16.6
err2023-10-09
err8
errOAAI
errKinnaman, Michael D.; Zaccaria, Simone; Makohon-Moore, Alvin; Arnold, Brian; Levine, Max F.; Gundem, Gunes; Arango Ossa, Juan E.; Glodzik, Dominik; Rodriguez-Sanchez, M. Irene; Bouvier, Nancy; Li, Shanita; Stockfisch, Emily; Dunigan, Marisa; Cobbs, Cassidy; Bhanot, Umesh K.; You, Daoqi; Mullen, Katelyn; Melchor, Jerry P.; Ortiz, Michael V.; O'Donohue, Tara J.; Slotkin, Emily K.; Wexler, Leonard H.; Dela Cruz, Filemon S.; Hameed, Meera R.; Glade Bender, Julia L.; Tap, William D.; Meyers, Paul A.; Papaemmanuil, Elli; Kung, Andrew L.; Iacobuzio-Donahue, Christine A.
err分享
err收藏
Clonal evolution during metastatic spread in high-risk neuroblastoma
errNATURE GENETICS
IF31.8
err2023-05-11
err12
errOAAI
errGundem, Gunes; Levine, Max F.; Roberts, Stephen S.; Cheung, Irene Y.; Medina-Martinez, Juan S.; Feng, Yi; Arango-Ossa, Juan E.; Chadoutaud, Loic; Rita, Mathieu; Asimomitis, Georgios; Zhou, Joe; You, Daoqi; Bouvier, Nancy; Spitzer, Barbara; Solit, David B.; Dela Cruz, Filemon; LaQuaglia, Michael P.; Kushner, Brian H.; Modak, Shakeel; Shukla, Neerav; Iacobuzio-Donahue, Christine A.; Kung, Andrew L.; Cheung, Nai-Kong V.; Papaemmanuil, Elli
err分享
err收藏
A Transcriptome-Based Precision Oncology Platform for Patient-Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies
errCANCER DISCOVERY
IF33.3
err2023-04-16
err9
errOAAI
errMundi, Prabhjot S.; Cruz, Filemon S. Dela; Grunn, Adina; Diolaiti, Daniel; Mauguen, Audrey; Rainey, Allison R.; Guillan, Kristina; Siddiquee, Armaan; You, Daoqi; Realubit, Ronald; Karan, Charles; Ortiz, Michael V.; Douglass, Eugene F.; Accordino, Melissa; Mistretta, Suzanne; Brogan, Frances; Bruce, Jeffrey N.; Caescu, Cristina I.; Carvajal, Richard D.; Crew, Katherine D.; Decastro, Guarionex; Heaney, Mark; Henick, Brian S.; Hershman, Dawn L.; Hou, June Y.; Iwamoto, Fabio M.; Jurcic, Joseph G.; Kiran, Ravi P.; Kluger, Michael D.; Kreisl, Teri; Lamanna, Nicole; Lassman, Andrew B.; Lim, Emerson A.; Manji, Gulam A.; Mckhann, Guy M.; Mckiernan, James M.; Neugut, Alfred I.; Olive, Kenneth P.; Rosenblat, Todd; Schwartz, Gary K.; Shu, Catherine A.; Sisti, Michael B.; Tergas, Ana; Vattakalam, Reena M.; Welch, Mary; Wenske, Sven; Wright, Jason D.; Canoll, Peter; Hibshoosh, Hanina; Kalinsky, Kevin; Aburi, Mahalaxmi; Sims, Peter A.; Alvarez, Mariano J.; Kung, Andrew L.; Califano, Andrea
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err收藏
Assessing patterns of genomic instability in recurrent osteosarcoma
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errKinnaman, Michael David; Zaccaria, Simone; Makohon-Moore, Alvin; Gundem, Gunes; Ossa, Juan E. Arango; Dela Cruz, Filemon S.; Meyers, Paul A.; Hameed, Meera; Tap, William D.; Bender, Julia Lynne Glade; Papaemmanuil, Elli; Kung, Andrew; Donahue, Christine Iacobuzio
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研究方向

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