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S

Shan-Liang Sun

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization
H指数:15
被引数:728

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Discovery of FYJ-195 as a Highly Potent FLT3 Inhibitor against Multiple Acquired Resistance Mutations in Acute Myeloid Leukemia

FYJ-195作为针对急性髓系白血病中多种获得性耐药突变的强效FLT3抑制剂的发现

Journal of Medicinal Chemistry
IF6.8
2026-05-230
PRE
Jin Yang; Ling-Yu Zhang; Xing-Feng Ni; Ming-Yu Bai; Xu Wang; An-Qi Fu; Min-Hui Chen; Meng-Yuan Zhang; Nuo Qiao; Zi-Xuan Wang; Qing-Qing Li; Shu Cai; Ying Wang; Yu-Sheng Yao; Yan-Cheng Yu; Wei-Dong Chen; Shan-Liang Sun; Zhang Zhang; Nian-Guang Li; Zhi-Hao Shi
Design, Synthesis, and Biological Evaluation of 3,4-Dihydroisoquinolin-1(2H)-one Derivatives as Protein Arginine Methyltransferase 5 Inhibitors for the Treatment of Non-Hodgkin's Lymphoma
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-12-260
PRE
Li, Qing-Qing; Quan, Xu; Wang, Zi-Xuan; Qiao, Nuo; Ni, Xing-Feng; Jing, Xiao-Long; Zhou, Shuang-Shuang; Tian, Xin-Lei; Zheng, Guo-Chuang; Zhan, Kang-Ning; Xu, Yu-Jing; Yang, Jin; Zhou, Yun; Liang, Xiao-Ting; Zhao, Zong-Hao; Wei, Tian-Hua; Liu, Qian; Bai, Ming-Yu; Sun, Shan-Liang; Yu, Yan-Cheng; Cao, Peng; Li, Nian-Guang; Zhang, Xiao-Meng; Liu, Jian; Shi, Zhi-Hao
Design, Synthesis, and Biological Activities Evaluation of Type I FLT3 Inhibitors for the Treatment of Acute Myeloid Leukemia
DRUG DEVELOPMENT RESEARCH
IF4.2
2024-11-210
PRE
Yang, Jin; Zhang, Yan; Li, Yue-Chu; Wang, Qing-Xin; Zhang, Meng-Yuan; Xu, Yu-Jing; Wang, Jing-Jing; Liang, Xiao-Ting; Jing, Xiao-Long; Zhou, Shuang-Shuang; Li, Qing-Qing; Wang, Zi-Xuan; Zhou, Yun; Qiao, Nuo; Wei, Tian-Hua; Ding, Ning; Xue, Xin; Yu, Yan-Cheng; Wang, Xiao-Long; Sun, Shan-Liang; Dai, Wei-Chen; Li, Nian-Guang; Shi, Zhi-Hao
Discovery of 1-(Phenylsulfonyl)-1,2,3,4-tetrahydroquinoline Derivative as Orally Bioavailable and Safe RORγt Inverse Agonists for Potential Treatment of Rheumatoid Arthritis
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-11-150
PRE
Sun, Shan-Liang; Xu, Hong-Jiang; Jiang, Xiao-Long; Zhou, Jian; Shi, Wei; Wang, Xiao-Jin; Song, Wei; Chang, Xia-Yun; Ma, Xue-Qin; Zou, Xiao-Fang; Wu, Shi-Han; Yang, Jin; Li, Qing-Qing; Wang, Zi-Xuan; Cai, Jiao; Yu, Shao-Peng; Wang, Qing-Xin; Wei, Tian-Hua; Wu, Jia-Zhen; Tong, Zhen-Jiang; Zhou, Yun; Wang, Yi-Bo; Yu, Yan-Cheng; Leng, Xue-Jiao; Ding, Ning; Shi, Zhi-Hao; Dai, Wei-Chen; Xue, Xin; Li, Nian-Guang; Wang, Xiao-Long
Design and synthesis 1H-Pyrrolo[2,3-b]pyridine derivatives as FLT3 inhibitors for the treatment of Acute myeloid Leukemia

1h-吡咯并 [2，3-b] 吡啶衍生物FLT3抑制剂的设计与合成，用于治疗急性髓系白血病

BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2024-02-011
PRE
Wei, Tian-Hua; Zhou, Yun; Yang, Jin; Zhang, Meng -Yuan; Wang, Jing-Jing; Tong, Zhen-Jiang; Wu, Jia-Zhen; Wang, Yi-Bo; Sha, Jiu-Kai; Chen, Min; Ding, Ning; Yu, Yan-Cheng; Dai, Wei -Chen; Leng, Xue-Jiao; Xue, Xin; Sun, Shan-Liang; Wang, Xiao-Long; Li, Nian-Guang; Shi, Zhi-Hao
Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia

danatinib作为新型FLT3抑制剂对耐药急性髓系白血病具有优异疗效的临床前特征

BIOMEDICINE & PHARMACOTHERAPY
IF7.5
2023-12-013
OAAI
Sun, Shan-Liang; Wu, Jia-Zhen; Wang, Jing-Jing; Zhou, Hai; Zhang, Chen-Qian; Tong, Zhen-Jiang; Wang, Yi-Bo; Sha, Jiu-Kai; Wang, Qing-Xin; Liu, Jia-Chuan; Zheng, Xin-Rui; Li, Qing-Qing; Zhang, Meng-Yuan; Yang, Jin; Wei, Tian-Hua; Wang, Zi-Xuan; Yu, Yan-Cheng; Ding, Ning; Leng, Xue-Jiao; Xue, Xin; Li, He-Min; Dai, Wei-Chen; Yin, Xiao-Ying; Yang, Ye; Duan, Jin-Ao; Li, Nian-Guang; Shi, Zhi-Hao

研究方向

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施
施志浩
H 指数:26论文数:103被引数:2,030
N
Nian‐Guang Li
H 指数:24论文数:142被引数:1,768
X
Xuejiao Leng
H 指数:12论文数:64被引数:523
T
Tian‐Hua Wei
H 指数:6论文数:30被引数:107
Y
Yan‐Cheng Yu
H 指数:6论文数:19被引数:103
Z
Zhen‐Jiang Tong
H 指数:6论文数:28被引数:114
杨烨 封面图
杨烨
H 指数:45论文数:355被引数:7,678
X
Xin Xue
H 指数:10论文数:31被引数:364
W
Wei‐Chen Dai
H 指数:10论文数:34被引数:216
J
Jia‐Zhen Wu
H 指数:5论文数:19被引数:88