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J

Jonathan Cairns

AstraZeneca
H指数:21
被引数:3,709

个人简介

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荣誉奖项

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Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system
COMMUNICATIONS BIOLOGY
IF5.1
2024-07-181
OAAI
Rigal, Sophie; Casas, Belen; Kanebratt, Kajsa P.; Huldt, Charlotte Wennberg; Magnusson, Lisa U.; Mullers, Erik; Karlsson, Fredrik; Clausen, Maryam; Hansson, Sara F.; Leonard, Louise; Cairns, Jonathan; Lofmark, Rasmus Jansson; Ammala, Carina; Marx, Uwe; Gennemark, Peter; Cedersund, Gunnar; Andersson, Tommy B.; Vilen, Liisa K.
Integrative dynamic MultiOMICs analysis identifies cell cycle and DNA damage response phenotypes as downstream consequences of using the PRMT5 inhibitor AZD3470
CANCER RESEARCH
IF16.6
2024-04-050
PRE
Hong, Ted; Criscione, Steven; Jarnuczak, Andrew; Urosevic, Jelena; Ashenden, Stephanie; Hamza, Ghaith; Kumar, Praveen; Cvetesic, Nevena; Bradshaw, Lauren; Moore, Shaun; Karl, Daniel; Zhang, Tianhui; Sousa, Abel; Cairns, Jonathan; Iannetta, Anthony; Zhang, Andrew; Miele, Eric; Reicha, John; Chambers, Chris; Elgendy, Ramy; Lindgren, Julia; Jachimowicz, Daniel; Clausen, Maryam; Belfield, Graham; Cheung, Tony; Grondine, Michael; Lynch, James T.; Chan, Ho Man; Critchlow, Susan; Dean, Emma
Impact of the physical-chemical properties of poly(lactic acid)-poly (ethylene glycol) polymeric nanoparticles on biodistribution
JOURNAL OF CONTROLLED RELEASE
IF11.5
2024-01-013
PRE
Jackman, Mark J.; Li, Weimin; Smith, Aaron; Workman, David; Treacher, Kevin E.; Corrigan, Adam; Abdulrazzaq, Fadi; Sonzini, Silvia; Nazir, Zahid; Lawrence, M. Jayne; Mahmoudi, Najet; Cant, David; Counsell, Jonathan; Cairns, Jonathan; Ferguson, Doug; Lenz, Eva; Baquain, Saif; Madla, Christine M.; van Pelt, Sally; Moss, Jennifer; Peter, Alison; Puri, Sanyogitta; Ashford, Marianne; Mazza, Mariarosa
The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance

下一代口服选择性雌激素受体降解剂Camizestrant (AZD9833) 抑制ER乳腺癌生长并克服内分泌和CDK4/6抑制剂抗性

CANCER RESEARCH
IF16.6
2023-09-1916
OAAI
Lawson, Mandy; Cureton, Natalie; Ros, Susana; Cheraghchi-Bashi, Azadeh; Urosevic, Jelena; D'Arcy, Sophie; Delpuech, Oona; Dupont, Michelle; Fisher, David I.; Gangl, Eric T.; Lewis, Hilary; Trueman, Dawn; Wali, Neha; Williamson, Stuart C.; Moss, Jennifer; Montaudon, Elodie; Derrien, Heloise; Marangoni, Elisabetta; Miragaia, Ricardo J.; Gagrica, Sladjana; Morentin-Gutierrez, Pablo; Moss, Thomas A.; Maglennon, Gareth; Sutton, Daniel; Polanski, Radoslaw; Rosen, Alan; Cairns, Jonathan; Zhang, Pei; Sanchez-Guixe, Monica; Serra, Violeta; Critchlow, Susan E.; Scott, James S.; Lindemann, Justin P. O.; Barry, Simon T.; Klinowska, Teresa; Morrow, Christopher J.; Carnevalli, Larissa
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity
NATURE COMMUNICATIONS
IF15.7
2019-11-07237
OAAI
Fok, Jacqueline H. L.; Ramos-Montoya, Antonio; Vazquez-Chantada, Mercedes; Wijnhoven, Paul W. G.; Follia, Valeria; James, Neil; Farrington, Paul M.; Karmokar, Ankur; Willis, Sophie E.; Cairns, Jonathan; Nikkila, Jenni; Beattie, David; Lamont, Gillian M.; Finlay, M. Raymond, V; Wilson, Joanne; Smith, Aaron; O'Connor, Lenka Oplustil; Ling, Stephanie; Fawell, Stephen E.; O'Connor, Mark J.; Hollingsworth, Simon J.; Dean, Emma; Goldberg, Frederick W.; Davies, Barry R.; Cadogan, Elaine B.
Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid
ARCHIVES OF TOXICOLOGY
IF6.9
2019-03-2676
OAAI
Foster, Alison J.; Chouhan, Bhavik; Regan, Sophie L.; Rollison, Helen; Amberntsson, Sara; Andersson, Linda C.; Srivastava, Abhishek; Darnell, Malin; Cairns, Jonathan; Lazic, Stanley E.; Jang, Kyung-Jin; Petropolis, Debora B.; Kodella, Konstantia; Rubins, Jonathan E.; Williams, Dominic; Hamilton, Geraldine A.; Ewart, Lorna; Morgan, Paul
Chromosome contacts in activated T cells identify autoimmune disease candidate genes
GENOME BIOLOGY
IF9.4
2017-09-0458
OAAI
Burren, Oliver S.; Garcia, Arcadio Rubio; Javierre, Biola-Maria; Rainbow, Daniel B.; Cairns, Jonathan; Cooper, Nicholas J.; Lambourne, John J.; Schofield, Ellen; Dopico, Xaquin Castro; Ferreira, Ricardo C.; Coulson, Richard; Burden, Frances; Rowlston, Sophia P.; Downes, Kate; Wingett, Steven W.; Frontini, Mattia; Ouwehand, Willem H.; Fraser, Peter; Spivakov, Mikhail; Todd, John A.; Wicker, Linda S.; Cutler, Antony J.; Wallace, Chris
Platelet function is modified by common sequence variation in megakaryocyte super enhancers
NATURE COMMUNICATIONS
IF15.7
2017-07-1338
OAAI
Petersen, Romina; Lambourne, John J.; Javierre, Biola M.; Grassi, Luigi; Kreuzhuber, Roman; Ruklisa, Dace; Rosa, Isabel M.; Tome, Ana R.; Elding, Heather; van Geffen, Johanna P.; Jiang, Tao; Farrow, Samantha; Cairns, Jonathan; Al-Subaie, Abeer M.; Ashford, Sofie; Attwood, Antony; Batista, Joana; Bouman, Heleen; Burden, Frances; Choudry, Fizzah A.; Clarke, Laura; Flicek, Paul; Garner, Stephen F.; Haimel, Matthias; Kempster, Carly; Ladopoulos, Vasileios; Lenaerts, An-Sofie; Materek, Paulina M.; McKinney, Harriet; Meacham, Stuart; Mead, Daniel; Nagy, Magdolna; Penkett, Christopher J.; Rendon, Augusto; Seyres, Denis; Sun, Benjamin; Tuna, Salih; van der Weide, Marie-Elise; Wingett, Steven W.; Martens, Joost H.; Stegle, Oliver; Richardson, Sylvia; Vallier, Ludovic; Roberts, David J.; Freson, Kathleen; Wernisch, Lorenz; Stunnenberg, Hendrik G.; Danesh, John; Fraser, Peter; Soranzo, Nicole; Butterworth, Adam S.; Heemskerk, Johan W.; Turro, Ernest; Spivakov, Mikhail; Ouwehand, Willem H.; Astle, William J.; Downes, Kate; Kostadima, Myrto; Frontini, Mattia

研究方向

暂未获取到该数据
S
Steven Wingett
H 指数:32论文数:122被引数:1.1万
P
Peter Fraser
H 指数:79论文数:379被引数:3.4万
M
Mikhail Spivakov
H 指数:39论文数:130被引数:9,867
M
Mayra Furlan-Magaril
H 指数:21论文数:59被引数:3,809
B
Biola M. Javierre
H 指数:31论文数:126被引数:7,037
P
Paula Freire-Pritchett
H 指数:14论文数:28被引数:2,853
C
Christopher J. Morrow
H 指数:27论文数:189被引数:3,743
T
Teresa Klinowska
H 指数:32论文数:249被引数:6,345
C
Csilla Várnai
H 指数:26论文数:69被引数:6,869
S
Stefan Schoenfelder
H 指数:35论文数:113被引数:1.1万