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E

Edward Rosfjord

Pfizer
H指数:23
被引数:2,757

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荣誉奖项

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Evaluation of the relationship between target expression and in vivo anti-tumor efficacy of AZD9592, an EGFR/c-MET targeted bispecific antibody drug conjugate

EGFR/c-met靶向双特异性抗体药物偶联物AZD9592的靶向表达与体内抗肿瘤疗效的关系评价

CANCER RESEARCH
IF16.6
2023-04-047
PRE
McGrath, Lara; Zheng, Ying; Christ, Simon; Sachs, Christian C.; Khelifa, Sihem; Windmuller, Claudia; Sweet, Steve; Kim, Yeoun Jin; Sutton, Daniel; Sulikowski, Michal; Lewis, Arthur; Inigo, Ivan; Floch, Nicolas; Rosfjord, Edward; Arnaldez, Fernanda; Comer, Frank
Comparison of Pyrrolobenzodiazepine Dimer Bis-imine versus Mono-imine: DNA Interstrand Cross-linking, Cytotoxicity, Antibody-Drug Conjugate Efficacy and Toxicity
MOLECULAR CANCER THERAPEUTICS
IF5.5
2022-12-023
OA
Tiberghien, Arnaud C.; Vijayakrishnan, Balakumar; Esfandiari, Arman; Ahmed, Mahammad; Pardo, Raul; Bingham, John; Adams, Lauren; Santos, Kathleen; Kang, Gyoung-Dong; Pugh, Kathryn M.; Afif-Rider, Shameen; Vashisht, Kapil; Haque, Kemal; Tammali, Ravinder; Rosfjord, Edward; Savoca, Adriana; Hartley, John A.; Howard, Philip W.
Anti-Extra Domain B Splice Variant of Fibronectin Antibody-Drug Conjugate Eliminates Tumors with Enhanced Efficacy When Combined with Checkpoint Blockade

纤连蛋白抗体-药物偶联物的抗外域B剪接变体与检查点阻断相结合可消除肿瘤，并提高疗效

MOLECULAR CANCER THERAPEUTICS
IF5.5
2022-07-069
OAAI
Hooper, Andrea T.; Marquette, Kimberly; Chang, Chao -Pei Betty; Golas, Jonathon; Jain, Sadhana; Lam, My-Hanh; Guffroy, Magali; Leal, Mauricio; Falahatpisheh, Hadi; Mathur, Divya; Chen, Ting; Kelleher, Kerry; Khandke, Kiran; Muszynska, Elwira; Loganzo, Frank; Rosfjord, Edward; Lucas, Judy; Kan, Zhengyan; Subramanyam, Chakrapani; O'Donnell, Christopher; Neri, Dario; Gerber, Hans-Peter; May, Chad; Sapra, Puja
Preclinical Evaluation of 89Zr-Df-IAB22M2C PET as an Imaging Biomarker for the Development of the GUCY2C-CD3 Bispecific PF-07062119 as a T Cell Engaging Therapy
MOLECULAR IMAGING AND BIOLOGY
IF2.5
2021-06-188
OAAI
Maresca, Kevin P.; Chen, Jianqing; Mathur, Divya; Giddabasappa, Anand; Root, Adam; Narula, Jatin; King, Lindsay; Schaer, David; Golas, Jonathan; Kobylarz, Keith; Rosfjord, Edward; Keliher, Edmund; Chen, Laigao; Ram, Sripad; Pickering, Eve H.; Hardwick, James S.; Rejto, Paul A.; Hussein, Amira; Ilovich, Ohad; Staton, Kevin; Wilson, Ian; McCarthy, Timothy J.
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors
MABS
IF7.3
2021-01-1810
OAAI
Root, Adam R.; Guntas, Gurkan; Katragadda, Madan; Apgar, James R.; Narula, Jatin; Chang, Chew Shun; Hanscom, Sara; McKenna, Matthew; Wade, Jason; Meade, Caryl; Ma, Weijun; Guo, Yongjing; Liu, Yan; Duan, Weili; Hendershot, Claire; King, Amy C.; Zhang, Yan; Sousa, Eric; Tam, Amy; Benard, Susan; Yang, Han; Kelleher, Kerry; Jin, Fang; Piche-Nicholas, Nicole; Keating, Sinead E.; Narciandi, Fernando; Lawrence-Henderson, Rosemary; Arai, Maya; Stochaj, Wayne R.; Svenson, Kristine; Mosyak, Lidia; Lam, Khetemcnee; Francis, Christopher; Marquette, Kimberly; Wroblewska, Liliana; Zhu, H. Lily; Sheehan, Alfredo Darmanin; LaVallie, Edward R.; D'Antona, Aaron M.; Betts, Alison; King, Lindsay; Rosfjord, Edward; Cunningham, Orla; Lin, Laura; Sapra, Puja; Tchistiakova, Lioudmila; Mathur, Divya; Bloom, Laird
PF-06804103, A Site-specific Anti-HER2 Antibody-Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers
MOLECULAR CANCER THERAPEUTICS
IF5.5
2020-10-0240
OAAI
Graziani, Edmund, I; Sung, Matthew; Ma, Dangshe; Narayanan, Bitha; Marquette, Kimberly; Puthenveetil, Sujiet; Tumey, L. Nathan; Bikker, Jack; Casavant, Jeffrey; Bennett, Eric M.; Charati, Manoj B.; Golas, Jonathon; Hosselet, Christine; Rohde, Cynthia M.; Hu, George; Guffroy, Magali; Falahatpisheh, Hadi; Finkelstein, Martin; Clark, Tracey; Barletta, Frank; Tchistiakova, Lioudmila; Lucas, Judy; Rosfjord, Edward; Loganzo, Frank; O'Donnell, Christopher J.; Gerber, Hans-Peter; Sapra, Puja
A novel GUCY2C-CD3 bispecific engages T cells to induce cytotoxicity in gastrointestinal tumors
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Mathur, Divya; Root, Adam; Bugaj-Gaweda, Bozena; Tan, Xingzhi; Fang, Wei; Bisulco, Stephanie; Golas, Jonathan; Fernandez, Diane; Kearney, Jessica; Upeslacis, Eric; Yao, Johnny; Rosfjord, Edward; Stevens, Chad; Kobylarz, Keith; King, Lindsay; Narula, Jatin; Kelleher, Kerry; Schaer, David; Kamperschroer, Cris; Buetow, Bernard; Rohde, Cynthia; Moreau, Allison; Wong, Gilbert; Sapra, Puja
A Novel GUCY2C-CD3 T-Cell Engaging Bispecific Construct (PF-07062119) for the Treatment of Gastrointestinal Cancers
CLINICAL CANCER RESEARCH
IF10.2
2020-05-0135
OA
Mathur, Divya; Root, Adam R.; Bugaj-Gaweda, Bozena; Bisulco, Stephanie; Tan, Xingzhi; Fang, Wei; Kearney, Jessica C.; Lucas, Justin; Guffroy, Magali; Golas, Jonathan; Rohde, Cynthia M.; Stevens, Chad; Kamperschroer, Cris; Kelleher, Kerry; Lawrence-Henderson, Rosemary F.; Upeslacis, Erik; Yao, Johnny; Narula, Jatin; LaVallie, Edward R.; Fernandez, Diane R.; Buetow, Bernard S.; Rosfjord, Edward; Bloom, Laird; King, Lindsay E.; Tchistiakova, Lioudmila; Nguyen, Anhco; Sapra, Puja
Cystine-glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity

胱氨酸-谷氨酸反向转运体xCT缺陷抑制肿瘤生长，同时保持抗肿瘤免疫力

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-04-24126
OAAI
Arensman, Michael D.; Yang, Xiaoran S.; Leahy, Danielle M.; Toral-Barza, Lourdes; Mileski, Mary; Rosfjord, Edward C.; Wang, Fang; Deng, Shibing; Myers, Jeremy S.; Abraham, Robert T.; Eng, Christina H.
A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2017-01-11138
PREAI
Damelin, Marc; Bankovich, Alexander; Bernstein, Jeffrey; Lucas, Justin; Chen, Liang; Williams, Samuel; Park, Albert; Aguilar, Jorge; Ernstoff, Elana; Charati, Manoj; Dushin, Russell; Aujay, Monette; Lee, Christina; Ramoth, Hanna; Milton, Milly; Hampl, Johannes; Lazetic, Sasha; Pulito, Virginia; Rosfjord, Edward; Sun, Yongliang; King, Lindsay; Barletta, Frank; Betts, Alison; Guffroy, Magali; Falahatpisheh, Hadi; O'Donnell, Christopher J.; Stull, Robert; Pysz, Marybeth; Escarpe, Paul; Liu, David; Foord, Orit; Gerber, Hans Peter; Sapra, Puja; Dylla, Scott J.
A novel PTK7-targeted antibody-drug conjugate eliminates tumor-initiating cells and induces sustained tumor regressions
CANCER RESEARCH
IF16.6
2016-07-150
PRE
Damelin, Marc Isaac; Bankovich, Alex; Bernstein, Jeff; Lucas, Justin; Chen, Liang; Williams, Sam; Park, Albert; Aguilar, Jorge; Ernstoff, Elana; Charati, Manoj; Dushin, Russell; Jackson-Fisher, Amy; Aujay, Monette; Lee, Christina; Ramoth, Hanna; Milton, Milly; Hampl, Johannes; Lazetic, Sasha; Pulito, Virginia; Armellino, Douglas; Rosfjord, Edward; Guffroy, Magali; Falahatpisheh, Hadi; King, Lindsay; Barletta, Frank; Stull, Robert; Pysz, Marybeth; Escarpe, Paul; Liu, David; Foord, Orit; Gibson, Brenda; Powell, Eric; O'Donnell, Christopher; Xin, Xiaohua; Gerber, Hans Peter; Sapra, Puja; Dylla, Scott

研究方向

暂未获取到该数据
J
Judy Lucas
H 指数:38论文数:190被引数:5,597
P
Puja Sapra
H 指数:35论文数:262被引数:4,825
J
Jonathon Golas
H 指数:10论文数:81被引数:539
H
Hans‐Peter Gerber
H 指数:58论文数:240被引数:2.7万
E
Erik Upeslacis
H 指数:6论文数:80被引数:482
J
Justin Lucas
H 指数:8论文数:87被引数:610
L
Lindsay King
H 指数:36论文数:348被引数:3,589
M
Magali Guffroy
H 指数:18论文数:124被引数:1,439
F
Frank Loganzo
H 指数:33论文数:124被引数:3,719
A
Andrea T. Hooper
H 指数:40论文数:190被引数:1.2万