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D

Darren Ennis

university of glasgow
H指数:25
被引数:3,207

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A tumour-derived organoid biobank maps cancer gene dependencies

肿瘤来源的类器官生物样本库绘制了癌症基因依赖图谱

Nature
IF48.5
2026-08-050
OA
C. Herranz-Ors; S. G. Bhosle; A. E. Beck; J. G. R. Gilbert; G. Picco; J. Espejo Valle-Inclan; F. Muyas; S. Valentini; A. E. Andres; R. Ansari; S. Barthorpe; G. Battarbee; C. M. Beaver; S. Brocklesby; J. Cantwell; C. A. Collins; J. Davis; H. G. Dimitrova; J. Doran; E. Efendi; K. Evans; M. Fekry; T. A. Fowler; M. Garcia-Casado; J. A. T. Griffiths; C. Hall; R. Hamer; C. Hardy; Z. Hewitson; E. Hitch; L. Holland; D. A. Jackson; N. Joshi; A. Kavasakali; L. Letchford; H. B. Lightfoot; H. Lingala; I. Mali; K. May; T. Mironenko; J. Morris; C. Pacini; S. Price; G. Robert-Tissot; H. A. Rogers; J. V. Smith; K. Smith; E. Souster; W. J. Spence; F. Thomas; S. F. Vieira; S. Walker; G. Alfonsin; H. Bermingham; H. Coles; D. P. Ennis; A. Freeman; G. Giannone; N. Grehan; E. A. Griffiths; J. Hall; S. L. Lee; E. Y. L. Leung; C. Loreno; C. Millington; A. Mirnezami; B. Nutzinger; K. Orzechowska; C. M. A. Pinna; A. M. Redmond; K. Roberts; S. Roy; D. A. Sanders; P. Taniere; M. Vias; K. Wanigasooriya; M. R. Stratton; L. M. Staudt; U. McDermott; J. D. Brenton; I. A. McNeish; A. Biankin; O. J. Sansom; I. Cortes-Ciriano; T. J. Underwood; R. C. Fitzgerald; A. D. Beggs; H. E. Francies; M. J. Garnett
Deciphering the role of complement system genes in pancreatic cancer susceptibility and prognosis

解析补体系统基因在胰腺癌易感性和预后中的作用

Nature Communications
IF15.7
2025-11-280
OAAI
Alberto Langtry; Raul Rabadan; Lola Alonso; Ioan Filip; Sergio Sabroso-Lasa; Ane Moreno-Oya; Rita Lawlor; Alfredo Carrato; Rafael Alvarez-Gallego; Mar Iglesias; Xavier Molero; Matthias J. Löhr; Christoph W. Michalski; José Perea; Michael O’Rorke; Victor M. Barberà; Adonina Tardón; Antoni Farré; Luís Muñoz-Bellvís; Tatjana Crnogorac-Jurcevic; Enrique Domínguez-Muñoz; Thomas M. Gress; William Greenhalf; Linda Sharp; Joaquim Balsells; Eithne Costello; Jörg Kleeff; Bo Kong; Josefina Mora; Damian O’Driscoll; Aldo Scarpa; Weimin Ye; Francisco X. Real; Evangelina López de Maturana; Núria Malats; Alberto Langtry; Lola Alonso; Sergio Sabroso-Lasa; Ane Moreno-Oya; Paulina Gómez-Rubio; Esther Molina-Montes; Mirari Márquez; Roger Milne; Ana Alfaro; Tania Lobato; Lidia Estudillo; Francisco X. Real; Núria Malats; Aldo Scarpa; Rita Lawlor; Stefania Beghelli; Rafael Alvarez-Gallego; Antonio Cubillo; Manuel Hidalgo; Paloma Peinado; Isabel Salas; Jesús Rodríguez Pascual; Alfredo Carrato; Julie Earl; Alejandra Caminoa; Carmen Guillén-Ponce; Mercedes Rodríguez-Garrote; Federico Longo-Muñoz; Reyes Ferreiro; Vanessa Pachón; M. Ángeles Vaz; María Muñoz; Mar Iglesias; Lucas Ilzarbe; Cristina Álvarez-Urturi; Xavier Bessa; Felipe Bory; Lucía Márquez; Ignasi Poves; Fernando Burdío; Luis Grande; Javier Gimeno; Xavier Molero; Luisa Guarner; Joaquín Balcells; Mayte Salcedo; Xavier Merino; Christoph W. Michalski; Irene Esposito; Jörg Kleeff; Bo Kong; Carmen Mota; Matthias J. Löhr; Jiaqui Huang; Caroline Verbeke; Weimin Ye; Jingru Yu; Carmelo Loinaz; José Perea; José Luis Rodríguez-Peralto; Ana Teijo; Pablo Peláez; Antoni Farré; Josefina Mora; Marta Martín; Vicenç Artigas; Carlos Guarner; Francesc J. Sancho; Mar Concepción; Teresa Ramón y Cajal; Justyna Szafranska; Michael O’Rorke; Liam Murray; Marie Cantwell; Victor M. Barberà; Javier Gallego; Adonina Tardón; Luis Barneo; MM Rodriguez-Suarez; Enrique Domínguez-Muñoz; Yolanda Pazos; Antonio Lozano; Maria Luaces; Francisco Blanco-Antona; J. M. Sayagués Manzano; M. L. Gutiérrez Troncoso; A. Orfao de Matos; Luís Muñoz-Bellvís; Thomas M. Gress; Malte Buchholz; Albrecht Neesse; William Greenhalf; Eithne Costello; Tatjana Crnogorac-Jurcevic; Hemant M. Kocher; Satyajit Bhattacharya; Ajit T. Abraham; Darren Ennis; Thomas Dowe; Tomasz Radon; Damian O’Driscoll; Linda Sharp
Identification of actionable targets using DEPArray-based sorting of pure carcinoma and stromal populations from formalin-fixed paraffin-embedded tissues followed by shallow whole-genome sequencing

通过DEPArray辅助的固定石蜡包埋组织中纯癌和基质细胞群的分选，结合浅层全基因组测序，鉴定可操作靶点

The Journal of Pathology
IF5.2
2025-10-270
OAAI
Georgios Nteliopoulos; Evie Wren; Amelia Rushton; Marc K Wadsley; Daniel Fernandez-Garcia; Floriana Manodoro; Otis Agbaimoni; Ritika Chauhan; Zhao Cheng; Darren P Ennis; Karen Page; Rebecca C Allsopp; Joel Bautista; Ignazio Puccio; Nik Matthews; Kelly LT Gleason; Rehman Farah; Laura Kenny; Iain A McNeish; Jacqueline A Shaw; R Charles Coombes
Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

Ewing, A.; Meynert, A.; Silk, R.; Aitken, S.; Bendixsen, D.P.; Churchman, M.; Brown, S.L.; Hamdan, A.; Mattocks, J.; Grimes, G.R.; 等. 结构多样性影响高级别浆液性卵巢癌患者生存的分歧轨迹。Nat. Commun. 2025, 16, 5586. [Google Scholar] [CrossRef] [PubMed]

Nature Communications
IF15.7
2025-07-010
OAAI
Ailith Ewing; Alison Meynert; Ryan Silk; Stuart Aitken; Devin P. Bendixsen; Michael Churchman; Stuart L. Brown; Alhafidz Hamdan; Joanne Mattocks; Graeme R. Grimes; Tracy Ballinger; Robert L. Hollis; C. Simon Herrington; John P. Thomson; Kitty Sherwood; Thomas Parry; Edward Esiri-Bloom; Clare Bartos; Ian Croy; Michelle Ferguson; Mairi Lennie; Trevor McGoldrick; Neil McPhail; Nadeem Siddiqui; Rosalind Glasspool; Melanie Mackean; Fiona Nussey; Brian McDade; Darren Ennis; Lynn McMahon; Athena Matakidou; Brian Dougherty; Ruth March; J. Carl Barrett; Iain A. McNeish; Andrew V. Biankin; Patricia Roxburgh; Charlie Gourley; Colin A. Semple
PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma
CANCER RESEARCH
IF16.6
2024-08-260
OAAI
Spear, Sarah; Le Saux, Olivia; Mirza, Hasan B.; Iyer, Nayana; Tyson, Katie; Freile, Fabio Grundland; Walton, Josephine B.; Woodman, Chloe; Jarvis, Sheba; Ennis, Darren P.; Hernandez, Carmen Aguirre; Xu, Yuewei; Spiliopoulou, Pavlina; Brenton, James D.; Costa-Pereira, Ana P.; Cook, David P.; Vanderhyden, Barbara C.; Keun, Hector C.; Triantafyllou, Evangelos; Arnold, James N.; Mcneish, Iain A.
Molecular landscape and functional characterization of centrosome amplification in ovarian cancer
NATURE COMMUNICATIONS
IF15.7
2023-10-164
OAAI
Sauer, Carolin M.; Hall, James A.; Couturier, Dominique-Laurent; Bradley, Thomas; Piskorz, Anna M.; Griffiths, Jacob; Sawle, Ashley; Eldridge, Matthew D.; Smith, Philip; Hosking, Karen; Reinius, Marika A. V.; Morrill Gavarro, Lena; Mes-Masson, Anne-Marie; Ennis, Darren; Millan, David; Hoyle, Aoisha; Mcneish, Iain A.; Jimenez-Linan, Mercedes; Martins, Filipe Correia; Tischer, Julia; Vias, Maria; Brenton, James D.
The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma (vol 14, 4387, 2023)
NATURE COMMUNICATIONS
IF15.7
2023-09-261
OAAI
Smith, Philip; Bradley, Thomas; Gavarro, Lena Morrill; Goranova, Teodora; Ennis, Darren P.; Mirza, Hasan B.; De Silva, Dilrini; Piskorz, Anna M.; Sauer, Carolin M.; Al-Khalidi, Sarwah; Funingana, Ionut-Gabriel; Reinius, Marika A. V.; Giannone, Gaia; Lewsley, Liz-Anne; Stobo, Jamie; McQueen, John; Bryson, Gareth; Eldridge, Matthew; Macintyre, Geoff; Markowetz, Florian; Brenton, James D.; McNeish, Iain A.
The copy number and mutational landscape of recurrent ovarian high-grade serous carcinoma
NATURE COMMUNICATIONS
IF15.7
2023-07-2015
OAAI
Smith, Philip; Bradley, Thomas; Gavarro, Lena Morrill; Goranova, Teodora; Ennis, Darren P.; Mirza, Hasan B.; De Silva, Dilrini; Piskorz, Anna M.; Sauer, Carolyn; Al-Khalidi, Sarwah; Funingana, Ionat-Gabriel; Reinius, Marika A. V.; Giannone, Gaia; Lewsley, Liz-Anne; Stobo, Jamie; McQueen, John; Bryson, Gareth; Eldridge, Matthew; Glasspool, R. M.; Gourley, C.; Kennedy, R.; Hall, G.; Edmondson, R.; Clamp, A.; Sundar, S.; Walter, A.; Hall, M.; Gabra, H.; Fotopoulou, C.; Brockbank, E.; Montes, A.; Lockley, M.; Macintyre, Geoff; Markowetz, Florian; Brenton, James D.; McNeish, Iain A.
Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin
CANCER RESEARCH
IF16.6
2022-10-0710
OAAI
Ho, Gwo Yaw; Kyran, Elizabeth L.; Bedo, Justin; Wakefield, Matthew J.; Ennis, Darren P.; Mirza, Hasan B.; Vandenberg, Cassandra J.; Lieschke, Elizabeth; Farrell, Andrew; Hadla, Anthony; Lim, Ratana; Dall, Genevieve; Vince, James E.; Chua, Ngee Kiat; Kondrashova, Olga; Upstill-Goddard, Rosanna; Bailey, Ulla-Maja; Dowson, Suzanne; Roxburgh, Patricia; Glasspool, Rosalind M.; Bryson, Gareth; Biankin, Andrew V.; Cooke, Susanna L.; Ratnayake, Gayanie; McNally, Orla; Traficante, Nadia; DeFazio, Anna; Weroha, S. John; Bowtell, David D.; McNeish, Iain A.; Papenfuss, Anthony T.; Scott, Clare L.; Barker, Holly E.
The Genomic Landscape of Early-Stage Ovarian High-Grade Serous Carcinoma
CLINICAL CANCER RESEARCH
IF10.2
2022-04-1022
OAAI
Cheng, Zhao; Mirza, Hasan; Ennis, Darren P.; Smith, Philip; Gavarro, Lena Morrill; Sokota, Chishimba; Giannone, Gaia; Goranova, Theodora; Bradley, Thomas; Piskorz, Anna; Lockley, Michelle; Kaur, Baljeet; Singh, Naveena; Tookman, Laura A.; Krell, Jonathan; McDermott, Jacqueline; Macintyre, Geoffrey; Markowetz, Florian; Brenton, James D.; McNeish, Iain A.
Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma
CLINICAL CANCER RESEARCH
IF10.2
2021-03-1927
OA
Ewing, Ailith; Meynert, Alison; Churchman, Michael; Grimes, Graeme R.; Hollis, Robert L.; Herrington, C. Simon; Rye, Tzyvia; Bartos, Clare; Croy, Ian; Ferguson, Michelle; Lennie, Mairi; McGoldrick, Trevor; McPhail, Neil; Siddiqui, Nadeem; Dowson, Suzanne; Glasspool, Rosalind; Mackean, Melanie; Nussey, Fiona; McDade, Brian; Ennis, Darren; McMahon, Lynn; Matakidou, Athena; Dougherty, Brian; March, Ruth; Barrett, J. Carl; McNeish, Iain A.; Biankin, Andrew, V; Roxburgh, Patricia; Gourley, Charlie; Semple, Colin A.
Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE)

高级别浆液性卵巢癌分子亚型 (前型) 基因表达预测因子的建立与验证

CLINICAL CANCER RESEARCH
IF10.2
2020-10-1550
OAAI
Talhouk, Aline; George, Joshy; Wang, Chen; Budden, Timothy; Tan, Tuan Zea; Chiu, Derek S.; Kommoss, Stefan; Leong, Huei San; Chen, Stephanie; Intermaggio, Maria P.; Gilks, Blake; Nazeran, Tayyebeh M.; Volchek, Mila; Elatre, Wafaa; Bentley, Rex C.; Senz, Janine; Lum, Amy; Chow, Veronica; Sudderuddin, Hanwei; Mackenzie, Robertson; Leong, Samuel C. Y.; Liu, Geyi; Johnson, Dustin; Chen, Billy; Alsop, Jennifer; Banerjee, Susana N.; Behrens, Sabine; Bodelon, Clara; Brand, Alison H.; Brinton, Louise; Carney, Michael E.; Chiew, Yoke-Eng; Cushing-Haugen, Kara L.; Cybulski, Cezary; Ennis, Darren; Fereday, Sian; Fortner, Renee T.; Garcia-Donas, Jesus; Gentry-Maharaj, Aleksandra; Glasspool, Rosalind; Goranova, Teodora; Greene, Casey S.; Haluska, Paul; Harris, Holly R.; Hendley, Joy; Hernandez, Brenda Y.; Herpel, Esther; Jimenez-Linan, Mercedes; Karpinskyj, Chloe; Kaufmann, Scott H.; Keeney, Gary L.; Kennedy, Catherine J.; Kobel, Martin; Koziak, Jennifer M.; Larson, Melissa C.; Lester, Jenny; Lewsley, Liz-Anne; Lissowska, Jolanta; Lubinski, Jan; Luk, Hugh; Macintyre, Geoff; Mahner, Sven; McNeish, Iain A.; Menkiszak, Janusz; Nevins, Nikilyn; Osorio, Ana; Oszurek, Oleg; Palacios, Jose; Hinsley, Samantha; Pearce, Celeste L.; Pike, Malcolm C.; Piskorz, Anna M.; Ray-Coquard, Isabelle; Rhenius, Valerie; Rodriguez-Antona, Cristina; Sharma, Raghwa; Sherman, Mark E.; De Silva, Dilrini; Singh, Naveena; Sinn, Peter; Slamon, Dennis; Song, Honglin; Steed, Helen; Stronach, Euan A.; Thompson, Pamela J.; Toloczko, Aleksandra; Trabert, Britton; Traficante, Nadia; Tseng, Chiu-Chen; Widschwendter, Martin; Wilkens, Lynne R.; Winham, Stacey J.; Winterhoff, Boris; Beeghly-Fadiel, Alicia; Benitez, Javier; Berchuck, Andrew; Brenton, James D.; Brown, Robert; Chang-Claude, Jenny; Chenevix-Trench, Georgia; DeFazio, Anna; Fasching, Peter A.; Garcia, Maria J.; Gayther, Simon A.; Goodman, Marc T.; Gronwald, Jacek; Henderson, Michelle J.; Karlan, Beth Y.; Kelemen, Linda E.; Menon, Usha; Orsulic, Sandra; Pharoah, Paul D. P.; Wentzensen, Nicolas; Wu, Anna H.; Schildkraut, Joellen M.; Rossing, Mary Anne; Konecny, Gottfried E.; Huntsman, David G.; Huang, Ruby Yun-Ju; Goode, Ellen L.; Ramus, Susan J.; Doherty, Jennifer A.; Bowtell, David D.; Anglesio, Michael S.
Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference

卵巢癌研究和治疗中的关键问题: 美国癌症研究协会特别会议的报告

CANCER
IF5.1
2019-03-0540
OAAI
Bast, Robert C., Jr.; Matulonis, Ursula A.; Sood, Anil K.; Ahmed, Ahmed A.; Amobi, Adaobi E.; Balkwill, Frances R.; Wielgos-Bonvallet, Monicka; Bowtell, David D. L.; Brenton, James D.; Brugge, Joan S.; Coleman, Robert L.; Draetta, Giulio F.; Doberstein, Kai; Drapkin, Ronny I.; Eckert, Mark A.; Edwards, Robert P.; Elias, Kevin M.; Ennis, Darren; Futreal, Andrew; Gershenson, David M.; Greenberg, Roger A.; Huntsman, David G.; Ji, Jennifer Xiao Ye; Kohn, Elise C.; Iavarone, Claudia; Lengyel, Ernst R.; Levine, Douglas A.; Lord, Christopher J.; Lu, Zhen; Mills, Gordon B.; Modugno, Francesmary; Nelson, Brad H.; Odunsi, Kunle; Pilsworth, Jessica A.; Rottapel, Robert K.; Powell, Daniel J., Jr.; Shen, Li; Shih, Ie-Ming; Spriggs, David R.; Walton, Josephine; Zhang, Kaiyang; Zhang, Rugang; Zou, Lee
Copy number signatures and mutational processes in ovarian carcinoma
NATURE GENETICS
IF31.8
2018-08-13286
OAAI
Macintyre, Geoff; Goranova, Teodora E.; De Silva, Dilrini; Ennis, Darren; Piskorz, Anna M.; Eldridge, Matthew; Sie, Daoud; Lewsley, Liz-Anne; Hanif, Aishah; Wilson, Cheryl; Dowson, Suzanne; Glasspool, Rosalind M.; Lockley, Michelle; Brockbank, Elly; Montes, Ana; Walther, Axel; Sundar, Sudha; Edmondson, Richard; Hall, Geoff D.; Clamp, Andrew; Gourley, Charlie; Hall, Marcia; Fotopoulou, Christina; Gabra, Hani; Paul, James; Supernat, Anna; Millan, David; Hoyle, Aoisha; Bryson, Gareth; Nourse, Craig; Mincarelli, Laura; Sanchez, Luis Navarro; Ylstra, Bauke; Jimenez-Linan, Mercedes; Moore, Luiza; Hofmann, Oliver; Markowetz, Florian; McNeish, Iain A.; Brenton, James D.

研究方向

暂未获取到该数据
I
Iain A. McNeish
H 指数:71论文数:781被引数:3.5万
H
Hasan Mirza
H 指数:13论文数:181被引数:802
J
James D. Brenton
H 指数:77论文数:677被引数:3.8万
S
Suzanne Dowson
H 指数:11论文数:118被引数:1,135
E
Elaine Leung
H 指数:25论文数:150被引数:3,976
K
Karen Blyth
H 指数:56论文数:413被引数:1.2万
F
Frances R. Balkwill
H 指数:105论文数:745被引数:6.6万
M
Matthew Eldridge
H 指数:55论文数:171被引数:2.3万
T
Teodora Goranova
H 指数:19论文数:59被引数:3,072
Z
Zhao Cheng
H 指数:12论文数:101被引数:363