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Targeting neddylation and sumoylation in chemoresistant triple negative breast cancer Powell, Reid T.; Rinkenbaugh, Amanda L.; Guo, Lei; Cai, Shirong; Shao, Jiansu; Zhou, Xinhui; Zhang, Xiaomei; Jeter-Jones, Sabrina; Fu, Chunxiao; Qi, Yuan; Hancock, Faiza Baameur; White, Jason B.; Stephan, Clifford; Davies, Peter J.; Moulder, Stacy; Symmans, W. Fraser; Chang, Jeffrey T.; Piwnica-Worms, Helen 分享 收藏
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers Lei, Guang; Mao, Chao; Horbath, Amber D.; Yan, Yuelong; Cai, Shirong; Yao, Jun; Jiang, Yan; Sun, Mingchuang; Liu, Xiaoguang; Cheng, Jun; Xu, Zhihao; Lee, Hyemin; Li, Qidong; Lu, Zhengze; Zhuang, Li; Chen, Mei-Kuang; Alapati, Anagha; Yap, Timothy A.; Hung, Mien-Chie; You, Mingjian James; Piwnica-Worms, Helen; Gan, Boyi 分享 收藏
PDX models of TNBC established from pre- and post-therapy tumors identify vulnerabilities of resistant disease Rinkenbaugh, Amanda L.; Qi, Yuan; Powell, Reid T.; Cai, Shirong; Shao, Jiansu; Hancock, Faiza Baameur; Guo, Lei; Zhang, Xiaomei; Jeter-Jones, Sabrina; Fu, Chunxiao; Gould, Rebekah; White, Jason B.; Stephan, Clifford; Echeverria, Gloria V.; Davies, Peter J.; Moulder, Stacy; Symmans, W. Fraser; Chang, Jeffrey T.; Piwnica-Worms, Helen 分享 收藏
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Targeting chemotherapy resistance in mesenchymal triple-negative breast cancer: a phase II trial of neoadjuvant angiogenic and mTOR inhibition with chemotherapy Abuhadra, Nour; Sun, Ryan; Bassett, Roland L.; Huo, Lei; Chang, Jeffrey T.; Teshome, Mediget; Clayborn, Alyson R.; White, Jason B.; Ravenberg, Elizabeth E.; Adrada, Beatriz E.; Candelaria, Rosalind P.; Yang, Wei; Ding, Qingqing; Symmans, W. Fraser; Arun, Banu; Damodaran, Senthil; Koenig, Kimberly B.; Layman, Rachel M.; Lim, Bora; Litton, Jennifer K.; Thompson, Alastair; Ueno, Naoto T.; Piwnica-Worms, Helen; Hortobagyi, Gabriel N.; Valero, Vicente; Tripathy, Debu; Rauch, Gaiane M.; Moulder, Stacy; Yam, Clinton 分享 收藏
NOS inhibition reverses epithelial-to-mesenchymal transition and synergizes with alpelisib in metaplastic breast cancer Reddy, Tejaswini P.; Puri, Akshjot; Guzman-Rojas, Liliana; Thomas, Christoforos; Qian, Wei; Zhou, Jianying; Zhao, Hong; Li, Xiaoxian; Mahboubi, Bijan; Oo, Adrian; Young-Jae, Cho; Kim, Baek; Thaiparambil, Jose; Chervo, Maria Florencia; Rosato, Roberto; Ayerbe, Camila; Giese, Noah; Moulder, Stacy; Piwnica-Worms, Helen; Meric-Bernstam, Funda; Chang, Jenny C. 分享 收藏
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New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases hPar-1激酶EMK和C-TAK1在调节IIa类组蛋白去乙酰化酶的定位和活性中的新作用 Dequiedt, Franck; Martin, Maud; Von Blume, Julia; Vertommen, Didier; Lecomte, Emily; Mari, Nathalie; Heinen, Marie-France; Bachmann, Malte; Twizere, Jean-Claude; Huang, Mei Chris; Rider, Mark H.; Piwnica-Worms, Helen; Seufferlein, Thomas; Kettmann, Richard 分享 收藏
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Loss of Par-1a/MARK3/C-TAK1 Kinase Leads to Reduced Adiposity, Resistance to Hepatic Steatosis, and Defective Gluconeogenesis Lennerz, Jochen K.; Hurov, Jonathan B.; White, Lynn S.; Lewandowski, Katherine T.; Prior, Julie L.; Planer, G. James; Gereau, Robert W.; Piwnica-Worms, David; Schmidt, Robert E.; Piwnica-Worms, Helen 分享 收藏
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