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E

Else Driehuis

Royal Netherlands Academy of Arts and Sciences and UMC Utrecht
H指数:17
被引数:4,503

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FER kinase governs invasive growth of head and neck squamous cell carcinoma through dynamic control of growth factor receptor activity

FER激酶通过动态调控生长因子受体活性来调控头颈鳞状细胞癌的浸润性生长。

Neoplasia
IF7.7
2025-10-190
OAAI
Peter D. Haughton; Lotte N.F.L. Enserink; Sandra Tavares; Wisse Haakma; Garik Galustjan; Sjors Koppes; Lorenza Casasanta; Else Driehuis; Hans Clevers; Yanchun Zhang; Gaofeng Fan; Stefan Willems; Xiaobao Yang; Patrick W.B. Derksen
Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7

表皮生长因子受体 (EGFR) 是肿瘤抑制因子E3连接酶FBXW7的靶标

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-03-143
OAAI
Borettoa, Matteo; Geurtsa, Maarten H.; Gandhia, Shashank; Mac, Zilian; Staliarovae, Nadzeya; Celottia, Martina; Lima, Sangho; Hea, Gui-Wei; Millena, Rosemary; Driehuisa, Else; Begthela, Harry; Smabersf, Lidwien; Roodhartf, Jeanine; van Esa, Johan; Wu, Wei; Clevers, Hans
Patient-derived head and neck cancer organoids allow treatment stratification and serve as a tool for biomarker validation and identification
MED
IF11.8
2023-05-0128
OA
Millen, Rosemary; De Kort, Willem W. B.; Koomen, Mandy; van Son, Gijs J. F.; Gobits, Roan; de Vries, Bas Penning; Begthel, Harry; Zandvliet, Maurice; Doornaert, Patricia; Raaijmakers, Cornelis P. J.; Geurts, Maarten H.; Elias, Sjoerd G.; van Es, Robert J. J.; de Bree, Remco; Devriese, Lot A.; Wilems, Stefan M.; Kranenburg, Onno; Driehuis, Else; Clevers, Hans
Rapid tissue prototyping with micro-organospheres br
STEM CELL REPORTS
IF5.1
2022-09-0119
OAAI
Wang, Zhaohui; Boretto, Matteo; Millen, Rosemary; Natesh, Naveen; Reckzeh, Elena S.; Hsu, Carolyn; Negrete, Marcos; Yao, Haipei; Quayle, William; Heaton, Brook E.; Harding, Alfred T.; Bose, Shree; Driehuis, Else; Beumer, Joep; Rivera, Grecia O.; van Ineveld, Ravian L.; Gex, Donald; DeVilla, Jessica; Wang, Daisong; Puschhof, Jens; Geurts, Maarten H.; Yeung, Athena; Hamele, Cait; Smith, Amber; Bankaitis, Eric; Xiang, Kun; Ding, Shengli; Nelson, Daniel; Delubac, Daniel; Rios, Anne; Abi-Hachem, Ralph; Jang, David; Goldstein, Bradley J.; Glass, Carolyn; Heaton, Nicholas S.; Hsu, David; Clevers, Hans; Shen, Xiling
Uncovering the mode of action of engineered T cells in patient cancer organoids

揭示工程改造的T细胞在患者癌症类器官中的作用方式

NATURE BIOTECHNOLOGY
IF41.7
2022-07-2579
OAAI
Dekkers, Johanna F.; Alieva, Maria; Cleven, Astrid; Keramati, Farid; Wezenaar, Amber K. L.; van Vliet, Esmee J.; Puschhof, Jens; Brazda, Peter; Johanna, Inez; Meringa, Angelo D.; Rebel, Heggert G.; Buchholz, Maj-Britt; Roman, Mario Barrera; Zeeman, Amber L.; de Blank, Sam; Fasci, Domenico; Geurts, Maarten H.; Cornel, Annelisa M.; Driehuis, Else; Millen, Rosemary; Straetemans, Trudy; Nicolasen, Mara J. T.; Aarts-Riemens, Tineke; Ariese, Hendrikus C. R.; Johnson, Hannah R.; van Ineveld, Ravian L.; Karaiskaki, Froso; Kopper, Oded; Bar-Ephraim, Yotam E.; Kretzschmar, Kai; Eggermont, Alexander M. M.; Nierkens, Stefan; Wehrens, Ellen J.; Stunnenberg, Henk G.; Clevers, Hans; Kuball, Jurgen; Sebestyen, Zsolt; Rios, Anne C.
Dutch National Round Robin Trial on Plasma-Derived Circulating Cell-Free DNA Extraction Methods Routinely Used in Clinical Pathology for Molecular Tumor Profiling
CLINICAL CHEMISTRY
IF6.3
2022-05-2514
OA
van der Leest, Paul; Ketelaar, Emma M.; van Noesel, Carel J. M.; van den Broek, Daan; van Boerdonk, Robert A. A.; Deiman, Birgit; Rifaela, Naomi; van der Geize, Robert; Huijsmans, Cornelis J. J.; Speel, Ernst Jan M.; Geerlings, Maartje J.; van Schaik, Ron H. N.; Jansen, Maurice P. H. M.; Dane-Vogelaar, Ria; Driehuis, Else; Leers, Mathie P. G.; Sidorenkov, Grigory; Tamminga, Menno; van Kempen, Leon C.; Schuuring, Ed
Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits
COMMUNICATIONS BIOLOGY
IF5.1
2022-01-1114
OAAI
Rodriguez, Ernesto; Boelaars, Kelly; Brown, Kari; Madunic, Katarina; van Ee, Thomas; Dijk, Frederike; Verheij, Joanne; Li, R. J. Eveline; Schetters, Sjoerd T. T.; Meijer, Laura L.; Le Large, Tessa Y. S.; Driehuis, Else; Clevers, Hans; Bruijns, Sven C. M.; O'Toole, Tom; van Vliet, Sandra J.; Bijlsma, Maarten F.; Wuhrer, Manfred; Kazemier, Geert; Giovannetti, Elisa; Garcia-Vallejo, Juan J.; van Kooyk, Yvette
Fasting-mimicking diet and hormone therapy modulates metabolic factors to promote breast cancer regression and reduce side effects
CANCER RESEARCH
IF16.6
2020-08-150
PRE
Caffa, Irene; Spagnolo, Vanessa; Becherini, Pamela; Valdemarin, Francesca; Vernieri, Claudio; Wei, Min; Brandhorst, S. Ebastian; Zucal, Chiara; Driehuis, Else; Ferrando, Lorenzo; Mastracci, Luca; Cilli, Michele; Piacente, Fra Ncesco; Cremonini, Anna Laura; Passalacqua, Mario; Vellone, Valerio; Zoppoli, Gabriele; Cea, Michele; Salvadori, Giulia; Cortellino, Salvatore; Clevers, Hans; De Braud, Filippo; Provenzani, Alessandro; Longo, Valter D.; Nencioni, Alessio
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening

胰腺癌类器官重述疾病并允许个性化药物筛选

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2019-12-09297
OAAI
Driehuis, Else; van Hoeck, Arne; Moore, Kat; Kolders, Sigrid; Francies, Hayley E.; Gulersonmez, M. Can; Stigter, Edwin C. A.; Burgering, Boudewijn; Geurts, Veerle; Gracanin, Ana; Bounova, Gergana; Morsink, Folkert H.; Vries, Robert; Boj, Sylvia; van Es, Johan; Offerhaus, G. Johan A.; Kranenburg, Onno; Garnett, Mathew J.; Wessels, Lodewyk; Cuppen, Edwin; Brosens, Lodewijk A. A.; Clevers, Hans
Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy
CANCER DISCOVERY
IF33.3
2019-07-01276
OAAI
Driehuis, Else; Kolders, Sigrid; Spelier, Sacha; Lohmussaar, Kadi; Willems, Stefan M.; Devriese, Lot A.; de Bree, Remco; de Ruiter, Emma J.; Korving, Jeroen; Begthel, Harry; Van Es, Johan H.; Geurts, Veerle; He, Gui-Wei; van Jaarsveld, Richard H.; Oka, Rurika; Muraro, Mauro J.; Vivie, Judith; Zandvliet, Maurice M. J. M.; Hendrickx, Antoni P. A.; Iakobachvili, Nino; Sridevi, Priya; Kranenburg, Onno; van Boxtel, Ruben; Kops, Geert J. P. L.; Tuveson, David A.; Peters, Peter J.; van Oudenaarden, Alexander; Clevers, Hans
Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer

类器官分析可确定胰腺癌对化疗的常见反应

CANCER DISCOVERY
IF33.3
2018-09-04647
OAAI
Tiriac, Herve; Belleau, Pascal; Engle, Dannielle D.; Plenker, Dennis; Deschenes, Astrid; Somerville, Tim D. D.; Froeling, Fieke E. M.; Burkhart, Richard A.; Denroche, Robert E.; Jang, Gun-Ho; Miyabayashi, Koji; Young, C. Megan; Patel, Hardik; Ma, Michelle; LaComb, Joseph F.; Palmaira, Randze Lerie D.; Javed, Ammar A.; Huynh, Jasmine C.; Johnson, Molly; Arora, Kanika; Robine, Nicolas; Shah, Minita; Sanghvi, Rashesh; Goetz, Austin B.; Lowder, Cinthya Y.; Martello, Laura; Driehuis, Else; LeComte, Nicolas; Askan, Gokce; Iacobuzio-Donahue, Christine A.; Clevers, Hans; Wood, Laura D.; Hruban, Ralph H.; Thompson, Elizabeth; Aguirre, Andrew J.; Wolpin, Brian M.; Sasson, Aaron; Kim, Joseph; Wu, Maoxin; Bucobo, Juan Carlos; Allen, Peter; Sejpal, Divyesh V.; Nealon, William; Sullivan, James D.; Winter, Jordan M.; Gimotty, Phyllis A.; Grem, Jean L.; DiMaio, Dominick J.; Buscaglia, Jonathan M.; Grandgenett, Paul M.; Brody, Jonathan R.; Hollingsworth, Michael A.; O'Kane, Grainne M.; Notta, Faiyaz; Kim, Edward; Crawford, James M.; Devoe, Craig; Ocean, Allyson; Wolfgang, Christopher L.; Yu, Kenneth H.; Li, Ellen; Vakoc, Christopher R.; Hubert, Benjamin; Fischer, Sandra E.; Wilson, Julie M.; Tt, Richard Moffi; Knox, Jennifer; Krasnitz, Alexander; Gallinger, Steven; Tuveson, David A.

研究方向

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H
Hans Clevers
H 指数:236论文数:1,340被引数:24.9万
S
Stefan M. Willems
H 指数:54论文数:371被引数:1.1万
W
Wisse E. Haakma
H 指数:5论文数:14被引数:241
L
Lot A. Devriese
H 指数:28论文数:142被引数:3,332
M
Maarten H. Geurts
H 指数:22论文数:34被引数:4,766
R
Rosemary Millen
H 指数:15论文数:35被引数:970
K
Kai Kretzschmar
H 指数:33论文数:111被引数:7,888
J
Johan H. van Es
H 指数:77论文数:197被引数:5.6万
O
Onno Kranenburg
H 指数:60论文数:359被引数:1.3万
R
Robert J.J. van Es
H 指数:35论文数:137被引数:3,580