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H

Hilda van den Bos

University of Groningen
H指数:17
被引数:885

个人简介

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教育背景

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工作经历

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荣誉奖项

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Single-cell chromosome and bulk transcriptome analysis as a diagnostic tool to differentiate between localized and metastatic pheochromocytoma and sympathetic paraganglioma

单细胞染色体和总体转录组分析作为诊断工具，以区分局限性及转移性嗜铬细胞瘤和交感神经副神经节瘤

ONCOGENE
IF7.3
2025-05-030
PRE
Berends, Annika M. A.; Wardenaar, Rene; van den Bos, Hilda; Tijhuis, Andrea E.; Links, Thera P.; Feelders, Richard A.; Hofland, Leo J.; Kruijff, Schelto; Pacak, Karel; Spierings, Diana C. J.; Kerstens, Michiel N.
Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway

骨肉瘤中TP53基因座的破坏导致TP53启动子基因融合和部分TP53信号通路的恢复

JOURNAL OF PATHOLOGY
IF5.2
2023-11-2710
OAAI
Saba, Karim H.; Difilippo, Valeria; Kovac, Michal; Cornmark, Louise; Magnusson, Linda; Nilsson, Jenny; van den Bos, Hilda; Spierings, Diana C. J.; Bidgoli, Mahtab; Jonson, Tord; Sumathi, Vaiyapuri P.; Brosjoe, Otte; Staaf, Johan; Foijer, Floris; Styring, Emelie; Nathrath, Michaela; Baumhoer, Daniel; Nord, Karolin H.
Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia
CANCER & METABOLISM
IF5.3
2023-04-210
OAAI
Rutten, Martijn G. S.; Lei, Yu; Hoogerland, Joanne H. H.; Bloks, Vincent W. W.; Yang, Hong; Bos, Trijnie; Krishnamurthy, Kishore A. A.; Bleeker, Aycha; Koster, Mirjam H. H.; Thomas, Rachel E. E.; Wolters, Justina C. C.; van den Bos, Hilda; Mithieux, Gilles; Rajas, Fabienne; Mardinoglu, Adil; Spierings, Diana C. J.; de Bruin, Alain; van de Sluis, Bart; Oosterveer, Maaike H. H.
Late-Stage Metastatic Melanoma Emerges through a Diversity of Evolutionary Pathways

晚期转移性黑色素瘤通过多种进化途径出现

CANCER DISCOVERY
IF33.3
2023-03-2819
OAAI
Spain, Lavinia; Coulton, Alexander; Lobon, Irene; Rowan, Andrew; Schnidrig, Desiree; Shepherd, Scott T. C.; Shum, Benjamin; Byrne, Fiona; Goicoechea, Maria; Piperni, Elisa; Au, Lewis; Edmonds, Kim; Carlyle, Eleanor; Hunter, Nikki; Renn, Alexandra; Messiou, Christina; Hughes, Peta; Nobbs, Jaime; Foijer, Floris; van den Bos, Hilda; Wardenaar, Rene; Spierings, Diana C. J.; Spencer, Charlotte; Schmitt, Andreas M.; Tippu, Zayd; Lingard, Karla; Grostate, Lauren; Peat, Kema; Kelly, Kayleigh; Sarker, Sarah; Vaughan, Sarah; Mangwende, Mary; Terry, Lauren; Kelly, Denise; Biano, Jennifer; Murra, Aida; Korteweg, Justine; Lewis, Charlotte; O'Flaherty, Molly; Cattin, Anne-Laure; Emmerich, Max; Gerard, Camille L.; Pallikonda, Husayn Ahmed; Lynch, Joanna; Mason, Robert; Rogiers, Aljosja; Xu, Hang; Huebner, Ariana; McGranahan, Nicholas; Al Bakir, Maise; Murai, Jun; Naceur-Lombardelli, Cristina; Borg, Elaine; Mitchison, Miriam; Moore, David A.; Falzon, Mary; Proctor, Ian; Stamp, Gordon W. H.; Nye, Emma L.; Young, Kate; Furness, Andrew J. S.; Pickering, Lisa; Stewart, Ruby; Mahadeva, Ula; Green, Anna; Larkin, James; Litchfield, Kevin; Swanton, Charles; Jamal-Hanjani, Mariam; Turajlic, Samra
Advanced melanoma exhibits a diversity of evolutionary routes to lethality

晚期黑色素瘤表现出致死率的进化途径的多样性

CANCER RESEARCH
IF16.6
2022-05-150
PRE
Coulton, Alexander; Lobon, Irene; Spain, Lavinia; Rowan, Andrew; Shnidrig, Desiree; Shepherd, Scott; Shum, Ben; Byrne, Fiona; Au, Lewis; Edmonds, Kim; Carlyle, Ellie; Renn, Alexandra; Messiou, Christina; Spencer, Charlotte; Schmidt, Andreas M.; Tippu, Zayd; Rogiers, Aljosja; Emmerich, Max; Gerard, Camille; Pallikonda, Husayn; Naceur-Lombardelli, Cristina; Foijer, Floris; van den Bos, Hilda; Wardenaar, Rene; Spierings, Diana; Young, Kate; Pickering, Lisa; Furness, Andrew; Borg, Elaine; Mitchison, Miriam; Moore, David; Falzon, Mary; Proctor, Ian; Stewart, Ruby; Mahadeva, Ula; Green, Anna; Larkin, James; Swanton, Charles; Jamal-Hanjani, Mariam; Litchfield, Kevin; Turajlic, Samra
Advanced melanoma exhibits a diversity of evolutionary routes to lethality
CANCER RESEARCH
IF16.6
2022-05-150
PRE
Coulton, Alexander; Lobon, Irene; Spain, Lavinia; Rowan, Andrew; Shnidrig, Desiree; Shepherd, Scott; Shum, Ben; Byrne, Fiona; Au, Lewis; Edmonds, Kim; Carlyle, Ellie; Renn, Alexandra; Messiou, Christina; Spencer, Charlotte; Schmidt, Andreas M.; Tippu, Zayd; Rogiers, Aljosja; Emmerich, Max; Gerard, Camille; Pallikonda, Husayn; Naceur-Lombardelli, Cristina; Foijer, Floris; van den Bos, Hilda; Wardenaar, Rene; Spierings, Diana; Young, Kate; Pickering, Lisa; Furness, Andrew; Borg, Elaine; Mitchison, Miriam; Moore, David; Falzon, Mary; Proctor, Ian; Stewart, Ruby; Mahadeva, Ula; Green, Anna; Larkin, James; Swanton, Charles; Jamal-Hanjani, Mariam; Litchfield, Kevin; Turajlic, Samra
The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma
PLOS GENETICS
IF3.7
2021-11-0926
OAAI
Bockaj, Irena; Martini, Tosca E., I; de Camargo Magalhaes, Eduardo S.; Bakker, Petra L.; Meeuwsen-de Boer, Tiny G. J.; Armandari, Inna; Meuleman, Saskia L.; Mondria, Marin T.; Stok, Colin; Kok, Yannick P.; Bakker, Bjorn; Wardenaar, Rene; Seiler, Jonas; Broekhuis, Mathilde J. C.; van den Bos, Hilda; Spierings, Diana C. J.; Ringnalda, Femke C. A.; Clevers, Hans; Schueller, Ulrich; van Vugt, Marcel A. T. M.; Foijer, Floris; Bruggeman, Sophia W. M.
PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis
EMBO REPORTS
IF6.2
2020-11-2329
OA
Sladky, Valentina C.; Knapp, Katja; Szabo, Tamas G.; Braun, Vincent Z.; Bongiovanni, Laura; van den Bos, Hilda; Spierings, Diana C. J.; Westendorp, Bart; Curinha, Ana; Stojakovic, Tatjana; Scharnagl, Hubert; Timelthaler, Gerald; Tsuchia, Kaoru; Pinter, Matthias; Semmler, Georg; Foijer, Floris; de Bruin, Alain; Reiberger, Thomas; Rohr-Udilova, Nataliya; Villunger, Andreas
Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice
GASTROENTEROLOGY
IF25.1
2019-07-0152
OAAI
Aziz, Khaled; Limzerwala, Jazeel F.; Sturmlechner, Ines; Hurley, Erin; Zhang, Cheng; Jeganathan, Karthik B.; Nelson, Grace; Bronk, Steve; Velasco, Raul O. Fierro; van Deursen, Erik-Jan; O'Brien, Daniel R.; Kocher, Jean-Pierre A.; Youssef, Sameh A.; van Ree, Janine H.; de Bruin, Alain; van den Bos, Hilda; Spierings, Diana C. J.; Foijer, Floris; van de Sluis, Bart; Roberts, Lewis R.; Gores, Gregory J.; Li, Hu; van Deursen, Jan M.
Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons

单细胞全基因组测序没有发现正常和阿尔茨海默病神经元中常见非整倍性的证据

GENOME BIOLOGY
IF9.4
2016-05-31102
OAAI
van den Bos, Hilda; Spierings, Diana C. J.; Taudt, Aaron S.; Bakker, Bjorn; Porubsky, David; Falconer, Ester; Novoa, Carolina; Halsema, Nancy; Kazemier, Hinke G.; Hoekstra-Wakker, Karina; Guryev, Victor; den Dunnen, Wilfred F. A.; Foijer, Floris; Tatche, Maria Colome; Boddeke, Hendrikus W. G. M.; Lansdorp, Peter M.

研究方向

暂未获取到该数据
D
Diana C.J. Spierings
H 指数:44论文数:290被引数:7,654
F
Floris Foijer
H 指数:42论文数:343被引数:5,708
P
Peter M. Lansdorp
H 指数:100论文数:417被引数:4.4万
R
René Wardenaar
H 指数:29论文数:198被引数:3,887
B
Björn Bakker
H 指数:27论文数:75被引数:3,524
M
Maria Colomé‐Tatché
H 指数:33论文数:118被引数:8,520
C
Christina Messiou
H 指数:51论文数:332被引数:1.2万
J
James Larkin
H 指数:128论文数:1,339被引数:13.2万
K
Kevin Litchfield
H 指数:52论文数:376被引数:1.3万
L
Lavinia Spain
H 指数:31论文数:187被引数:8,697