logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
arrow
A

Amanda Swain

The Institute of Cancer Research
H指数:36
被引数:1.1万

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

IAP antagonist tolinapant (ASTX660) in combination with pembrolizumab in advanced solid tumors: a phase I trial

IAP拮抗剂托利那潘特（ASTX660）联合帕博利珠单抗治疗晚期实体瘤：一项I期临床试验

Nature Communications
IF15.7
2026-09-300
OA
Crescens Tiu; Wing Yau; Tencho Tenev; Daniel Lionarons; Ching Leung; Victoria Sanchez-Perez; Giovanni Codacci-Pisanelli; Xiaoran Lai; Anna Zachariou; Aasia Hussain; Toby Prout; Mona Parmar; Bindu Baikady; Maria Goicoechea; Scott Layzell; Naomi Guppy; Ioannis Roxanis; Thomas Lund; Diego Carlos Dos Reis; Camila Pereira Almeida; Tatiany Luiza Silveira; Ana Ferreira; Bora Gurel; Claudia Bertan; Mateus Crespo; Penny Flohr; Ann-Marie Baker; Trevor Graham; Luis Zapata; Claudio Salas; Soham Mandal; Alan Dunlop; Martin Sims; George Ward; Tomoko Smyth; Simone Jueliger; Matthew Davis; Ilya Potapov; Aram Oganesian; Danna Chan; Mattias Leino; Subham Basu; Andre Samson; James M. Murphy; Nina Tunariu; Edward W. Johnston; Alistair Ring; Nick Turner; Andrew N. J. Tutt; Amanda Swain; Anna Minchom; Adam Sharp; Alec Paschalis; Udai Banerji; Johann de Bono; Bristi Basu; Christina Yap; Syed Haider; Juanita Lopez; Pascal Meier
Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer

阐明靶向MCL1的分子分层单药及联合治疗策略，以治疗致命性前列腺癌

Nature Communications
IF15.7
2025-10-080
OAAI
Juan M. Jiménez-Vacas; Daniel Westaby; Ines Figueiredo; Alexis De Haven Brandon; Ana Padilha; Wei Yuan; George Seed; Denisa Bogdan; Bora Gurel; Claudia Bertan; Susana Miranda; Maryou Lambros; Antonio J. Montero-Hidalgo; Ilsa Coleman; Ivan Pak Lok Yu; Lorenzo Buroni; Wanting Zeng; Antje J. Neeb; Jon Welti; Jan Rekowski; Roberta Paravati; Florian Gabel; Nicole Pandell; Ana Ferreira; Mateus Crespo; Ruth Riisnaes; Souvik Das; Joe Taylor; Nick Waldron; Emily Hobern; Melanie Valenti; Jian Ning; Ilona Bernett; Kate Liodaki; Thomas Persse; Patricia Galipeau; Scott Wilkinson; Shana Y. Trostel; Fatima Karzai; Cindy H. Chau; Erica L. Beatson; Xiaohu Zhang; Carleen Klumpp-Thomas; Andreas Varkaris; Raul M. Luque; Amanda Swain; Florence Raynaud; Nathan A. Lack; Craig J. Thomas; Gavin Ha; William D. Figg; Marco Bezzi; Adam G. Sowalsky; Peter S. Nelson; Suzanne Carreira; Steven P. Balk; Johann S. de Bono; Adam Sharp
Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-02-272
OAAI
Neeb, Antje; Figueiredo, Ines; Bogdan, Denisa; Cato, Laura; Stober, Jutta; Jimenez-Vacas, Juan M.; Gourain, Victor; Lee, Irene I.; Seeger, Rebecca; Muhle-Goll, Claudia; Gurel, Bora; Welti, Jonathan; Nava Rodrigues, Daniel; Rekowski, Jan; Qiu, Xintao; Jiang, Yija; Di Micco, Patrizio; Mateos, Borja; Bielskute, Stase; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Crespo, Mateus; Buroni, Lorenzo; Ning, Jian; Carreira, Suzanne; Braese, Stefan; Jung, Nicole; Graessle, Simone; Swain, Amanda; Salvatella, Xavier; Plymate, Stephen R.; Al-Lazikani, Bissan; Long, Henry W.; Yuan, Wei; Brown, Myles; Cato, Andrew C. B.; de Bono, Johann S.; Sharp, Adam
Advanced Prostate Cancer with ATM Loss: PARP and ATR Inhibitors
EUROPEAN UROLOGY
IF25.2
2021-02-0186
OAAI
Neeb, Antje; Herranz, Nicolas; Arce-Gallego, Sara; Miranda, Susana; Buroni, Lorenzo; Yuan, Wei; Athie, Alejandro; Casals, Teresa; Carmichael, Juliet; Nava Rodrigues, Daniel; Gurel, Bora; Rescigno, Pasquale; Rekowski, Jan; Welti, Jon; Riisnaes, Ruth; Gil, Veronica; Ning, Jian; Wagner, Verena; Casanova-Salas, Irene; Cordoba, Sarai; Castro, Natalia; Fenor de la Maza, Maria Dolores; Seed, George; Chandran, Khobe; Ferreira, Ana; Figueiredo, Ines; Bertan, Claudia; Bianchini, Diletta; Aversa, Caterina; Paschalis, Alec; Gonzalez, Macarena; Morales-Barrera, Rafael; Suarez, Cristina; Carles, Joan; Swain, Amanda; Sharp, Adam; Gil, Jesus; Serra, Violeta; Lord, Christopher; Carreira, Suzanne; Mateo, Joaquin; de Bono, Johann S.
Targeting the p300/CBP Axis in Lethal Prostate Cancer

靶向p300/CBP轴在致死性前列腺癌中的作用

CANCER DISCOVERY
IF33.3
2021-01-11152
OA
Welti, Jonathan; Sharp, Adam; Brooks, Nigel; Yuan, Wei; McNair, Christopher; Chand, Saswati N.; Pal, Abhijit; Figueiredo, Ines; Riisnaes, Ruth; Gurel, Bora; Rekowski, Jan; Bogdan, Denisa; West, William; Young, Barbara; Raja, Meera; Prosser, Amy; Lane, Jordan; Thomson, Stuart; Worthington, Jenny; Onions, Stuart; Shannon, Jonathan; Paoletta, Silvia; Brown, Richard; Smyth, Don; Harbottle, Gareth W.; Gil, Veronica S.; Miranda, Susana; Crespo, Mateus; Ferreira, Ana; Pereira, Rita; Tunariu, Nina; Carreira, Suzanne; Neeb, Antje J.; Ning, Jian; Swain, Amanda; Taddei, David; Schiewer, Matthew J.; Knudsen, Karen E.; Pegg, Neil; de Bono, Johann S.
Androgen receptor-modulatory microRNAs provide insight into therapy resistance and therapeutic targets in advanced prostate cancer
ONCOGENE
IF7.3
2019-05-0161
OAAI
Fletcher, Claire E.; Sulpice, Eric; Combe, Stephanie; Shibakawa, Akifumi; Leach, Damien A.; Hamilton, Mark P.; Chrysostomou, Stelios L.; Sharp, Adam; Welti, Jon; Yuan, Wei; Dart, Dafydd A.; Knight, Eleanor; Ning, Jian; Francis, Jeffrey C.; Kounatidou, Evangelia E.; Gaughan, Luke; Swain, Amanda; Lupold, Shawn E.; de Bono, Johann S.; McGuire, Sean E.; Gidrol, Xavier; Bevan, Charlotte L.
CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer organoids
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2019-04-1581
OAAI
Gonzalez-Exposito, Reyes; Semiannikova, Maria; Griffiths, Beatrice; Khan, Khurum; Barber, Louise J.; Woolston, Andrew; Spain, Georgia; von Loga, Katharina; Challoner, Ben; Patel, Radhika; Ranes, Michael; Swain, Amanda; Thomas, Janet; Bryant, Annette; Saffery, Claire; Fotiadis, Nicos; Guettler, Sebastian; Mansfield, David; Melcher, Alan; Powles, Thomas; Rao, Sheela; Watkins, David; Chau, Ian; Matthews, Nik; Wallberg, Fredrik; Starling, Naureen; Cunningham, David; Gerlinger, Marco
Targeting the bromodomain and extra-terminal (BET) family proteins and beyond in metastatic castration-resistant prostate cancer (mCRPC): Overcoming aberrant androgen receptor (AR) signaling.
CANCER RESEARCH
IF16.6
2018-08-140
PRE
Sharp, Adam; Welti, Jon; Yuan, Wei; Figueiredo, Ines; Gil, Veronica; Rodrigues, Daniel Nava; Lambros, Maryou; Knight, Eleanor; Ning, Jian; Francis, Jeff; Dolling, David; Pope, Lorna; Neeb, Antje; Boysen, Gunther; Zhu, Yezi; Crespo, Mateus; Paschalis, Alec; Luo, Jun; Plymate, Stephen; Al-Lazikani, Bissan; Swain, Amanda; de Bono, Johann
Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC)
CLINICAL CANCER RESEARCH
IF10.2
2018-07-01117
OAAI
Welti, Jonathan; Sharp, Adam; Yuan, Wei; Dolling, David; Rodrigues, Daniel Nava; Figueiredo, Ines; Gil, Veronica; Neeb, Antje; Clarke, Matthew; Seed, George; Crespo, Mateus; Sumanasuriya, Semini; Ning, Jian; Knight, Eleanor; Francis, Jeffrey C.; Hughes, Ashley; Halsey, Wendy S.; Paschalis, Alec; Mani, Ram S.; Raj, Ganesh V.; Plymate, Stephen R.; Carreira, Suzanne; Boysen, Gunther; Chinnaiyan, Arul M.; Swain, Amanda; de Bono, Johann S.
Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance
NATURE COMMUNICATIONS
IF15.7
2018-05-10335
OAAI
Pettitt, Stephen J.; Krastev, Dragomir B.; Brandsma, Inger; Drean, Amy; Song, Feifei; Aleksandrov, Radoslav; Harrell, Maria I.; Menon, Malini; Brough, Rachel; Campbell, James; Frankum, Jessica; Ranes, Michael; Pemberton, Helen N.; Rafiq, Rumana; Fenwick, Kerry; Swain, Amanda; Guettler, Sebastian; Lee, Jung-Min; Swisher, Elizabeth M.; Stoynov, Stoyno; Yusa, Kosuke; Ashworth, Alan; Lord, Christopher J.

研究方向

暂未获取到该数据
J
Jian Ning
H 指数:9论文数:84被引数:1,000
J
Johann S. de Bono
H 指数:160论文数:2,491被引数:13.4万
A
Adam Sharp
H 指数:41论文数:495被引数:6,077
A
Antje Neeb
H 指数:31论文数:315被引数:4,334
W
Wei Yuan
H 指数:58论文数:229被引数:1.2万
M
Mateus Crespo
H 指数:41论文数:365被引数:5,764
J
Jeffrey C. Francis
H 指数:12论文数:36被引数:983
C
Christopher J. Lord
H 指数:98论文数:708被引数:4.5万
R
Ruth Riisnaes
H 指数:41论文数:442被引数:9,977
B
Bora Gürel
H 指数:37论文数:417被引数:7,026