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Anti-tumoural activity of the G-quadruplex ligand pyridostatin against BRCA1/2-deficient tumours Groelly, Florian J.; Porru, Manuela; Zimmer, Jutta; Benainous, Hugo; De Visser, Yanti; Kosova, Anastasiya A.; Di Vito, Serena; Serra, Violeta; Ryan, Anderson; Leonetti, Carlo; Bruna, Alejandra; Biroccio, Annamaria; Tarsounas, Madalena 分享 收藏
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Safety and activity of vandetanib in combination with everolimus in patients with advanced solid tumors: a phase I study Cascone, T.; Sacks, R. L.; Subbiah, I. M.; Drobnitzky, N.; Piha-Paul, S. A.; Hong, D. S.; Hess, K. R.; Amini, B.; Bhatt, T.; Fu, S.; Naing, A.; Janku, F.; Karp, D.; Falchook, G. S.; Conley, A. P.; Sherman, S., I; Meric-Bernstam, F.; Ryan, A. J.; Heymach, J., V; Subbiah, V 分享 收藏
Olaparib increases the therapeutic index of hemithoracic irradiation compared with hemithoracic irradiation alone in a mouse lung cancer model Jiang, Yanyan; Martin, Jennifer; Alkadhimi, Maryam; Shigemori, Kay; Kinchesh, Paul; Gilchrist, Stuart; Kersemans, Veerle; Smart, Sean; Thompson, James M.; Hill, Mark A.; O'Connor, Mark J.; Davies, Barry R.; Ryan, Anderson J. 分享 收藏
Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response Zhang, Ping; Kitchen-Smith, Isaac; Xiong, Lingyun; Stracquadanio, Giovanni; Brown, Katherine; Richter, Philipp H.; Wallace, Marsha D.; Bond, Elisabeth; Sahgal, Natasha; Moore, Samantha; Nornes, Svanhild; De Val, Sarah; Surakhy, Mirvat; Sims, David; Wang, Xuting; Bell, Douglas A.; Zeron-Medina, Jorge; Jiang, Yanyan; Ryan, Anderson J.; Selfe, Joanna L.; Shipley, Janet; Kar, Siddhartha; Pharoah, Paul D.; Loveday, Chey; Jansen, Rick; Grochola, Lukasz F.; Palles, Claire; Protheroe, Andrew; Millar, Val; Ebner, Daniel, V; Pagadala, Meghana; Blagden, Sarah P.; Maughan, Timothy S.; Domingo, Enric; Tomlinson, Ian; Turnbull, Clare; Carter, Hannah; Bond, Gareth L. 分享 收藏
Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction Rieunier, Guillaume; Wu, Xiaoning; Harris, Letitia E.; Mills, Jack, V; Nandakumar, Ashwin; Colling, Laura; Seraia, Elena; Hatch, Stephanie B.; Ebner, Daniel, V; Folkes, Lisa K.; Weyer-Czernilofsky, Ulrike; Bogenrieder, Thomas; Ryan, Anderson J.; Macaulay, Valentine M. 分享 收藏
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Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy Willoughby, Catherine E.; Jiang, Yanyan; Thomas, Huw D.; Willmore, Elaine; Kyle, Suzanne; Wittner, Anita; Phillips, Nicole; Zhao, Yan; Tudhope, Susan J.; Prendergast, Lisa; Junge, Gesa; Lourenco, Luiza Madia; Finlay, M. Raymond V.; Turner, Paul; Munck, Joanne M.; Griffin, Roger J.; Rennison, Tommy; Pickles, James; Cano, Celine; Newell, David R.; Reeves, Helen L.; Ryan, Anderson J.; Wedge, Stephen R. 分享 收藏
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Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance Tacconi, Eliana M. C.; Badie, Sophie; De Gregoriis, Giuliana; Reislander, Timo; Lai, Xianning; Porru, Manuela; Folio, Cecilia; Moore, John; Kopp, Arnaud; Torres, Julia Baguna; Sneddon, Deborah; Green, Marcus; Dedic, Simon; Lee, Jonathan W.; Batra, Ankita Sati; Rueda, Oscar M.; Bruna, Alejandra; Leonetti, Carlo; Caldas, Carlos; Cornelissen, Bart; Brino, Laurent; Ryan, Anderson; Biroccio, Annamaria; Tarsounas, Madalena 分享 收藏