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P

Petra Kollárová-Brázdová

Charles University Prague
H指数:6
被引数:153

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Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection

Topobexin靶向Topoisomerase II ATPase结构域，以实现β异构体选择性抑制和蒽环类心脏保护。

NATURE COMMUNICATIONS
IF15.7
2025-05-280
OA
Kubes, Jan; Karabanovich, Galina; Cong, Anh T. Q.; Melnikova, Iuliia; Lencova, Olga; Kollarova, Petra; Bavlovic Piskackova, Hana; Kerestes, Veronika; Applova, Lenka; Arrouye, Lise C. M.; Alvey, Julia R.; Paluncic, Jasmina; Witter, Taylor L.; Jirkovska, Anna; Kunes, Jiri; Sterbova-Kovarikova, Petra; Austin, Caroline A.; Sterba, Martin; Simunek, Tomas; Roh, Jaroslav; Schellenberg, Matthew J.
Cardioprotective Effects Of Dexrazoxane Derivatives Against Chronic Anthracycline Cardiotoxicity Depend On Topoisomerase II Beta Inhibition And Prevention Of DNA Damage Signaling In The Heart

右雷佐生衍生物对慢性蒽环类药物心脏毒性的心脏保护作用取决于拓扑异构酶II β 的抑制作用和心脏DNA损伤信号的预防

CIRCULATION RESEARCH
IF16.2
2022-08-050
PRE
Kollarova, Petra; Lencova, Olga; Karabanovich, Galina; Kubes, Jan; Vanova, Nela; Roh, Jaroslav; Simunek, Tomas; Sterbova, Petra; Sterba, Martin
Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation

右雷佐生对蒽环类药物心脏毒性的临床上可翻译的预防是由拓扑异构酶II β 介导的，而不是金属螯合

jacc heart failure
IF8.4
2021-11-0139
OA
Jirkovsky, Eduard; Jirkovska, Anna; Bavlovic-Piskackova, Hana; Skalicka, Veronika; Pokorna, Zuzana; Karabanovich, Galina; Kollarova-Brazdova, Petra; Kubes, Jan; Lencova-Popelova, Olga; Mazurova, Yvona; Adamcova, Michaela; Lyon, Alexander R.; Roh, Jaroslav; Simunek, Tomas; Sterbova-Kovarikova, Petra; Sterba, Martin
Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase IIβ Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
2020-06-0114
OAAI
Kollarova-Brazdova, Petra; Jirkovska, Anna; Karabanovich, Galina; Pokorna, Zuzana; Piskackova, Hana Bavlovic; Jirkovsky, Eduard; Kubes, Jan; Lencova-Popelova, Olga; Mazurova, Yvona; Adamcova, Michaela; Skalicka, Veronika; Sterbova-Kovarikova, Petra; Roh, Jaroslav; Simunek, Tomas; Sterba, Martin

研究方向

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M
Martin Štěrba
H 指数:32论文数:129被引数:4,462
J
Jan Kubeš
H 指数:9论文数:25被引数:239
T
Tomáš Šimůnek
H 指数:35论文数:113被引数:4,042
G
Galina Karabanovich
H 指数:13论文数:37被引数:685
J
Jaroslav Roh
H 指数:24论文数:88被引数:1,920
O
Olga Lenčová-Popelová
H 指数:10论文数:22被引数:320
H
Hana Bavlovič Piskáčková
H 指数:8论文数:16被引数:214
P
Petra Štěrbová‐Kovaříková
H 指数:9论文数:22被引数:237
M
Michaela Adamcová
H 指数:32论文数:128被引数:3,310
A
Anna Jirkovská
H 指数:14论文数:28被引数:392