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Jianzhu Chen 封面图

Jianzhu Chen (Jianzhu Chen)

massachusetts institute of technology

72H指数
299论文数
2.1W被引数
收录论文 151
发表时间
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Preclinical Development of ARV-2001, an Intradermally Administered mRNA–Lipid Nanoparticle Immunotherapeutic for the Treatment of HPV-16-Positive Cervical High-Grade Squamous Intraepithelial LesionsARV-2001的临床前开发：一种用于治疗HPV-16阳性宫颈高级别鳞状上皮内病变的皮内注射mRNA-脂质纳米粒免疫疗法
errVaccines
IF3.4
err2026-08-30
err0
errOAAI
errZhengxiang He; Huabin Zhu; Ju Hyeong Jeon; Jianzhu Chen; Gregory M. Glenn; Renhuan Xu
err分享
err收藏
High-recovery AAV clarification using a multiplexed spiral inertial microfluidic platform基于多通道螺旋惯性微流控平台的高回收率AAV纯化
errlab chip
IF0
err2026-05-09
err0
PREAI
errAlexander Bevacqua; Do Hyun Park; Sheryar Khan; Qingxuan Li; Mahsa Hadidi; Jianzhu Chen; Jongyoon Han
err分享
err收藏
Intensified lentiviral vector perfusion bioprocessing with a spiral inertial microfluidic cell retention device强化型慢病毒载体灌注生物加工，采用螺旋惯性微流控细胞保留装置
errlab chip
IF0
err2026-03-11
err0
errOAAI
errAlexander Bevacqua; Fuguo Liu; Jianzhu Chen; Jongyoon Han
err分享
err收藏
Selective HLA knockdown and PD-L1 expression prevent allogeneic CAR-NK cell rejection and enhance safety and anti-tumor responses in xenograft mice选择性HLA敲低和PD-L1表达可防止异基因CAR-NK细胞被排斥，并增强异种移植小鼠模型中的安全性和抗肿瘤反应。
errNature Communications
IF15.7
err2025-10-08
err0
errOAAI
errFuguo Liu; Mubin Tarannum; Yingjie Zhao; Yiming J. Zhang; James Dongjoo Ham; Kewen Lei; Yuhao Qiang; Xingyu Deng; Maily Nguyen; Khanhlinh Dinh; Shaobo Yang; Alaa Kassim Ali; Toni K. Choueiri; Jerome Ritz; Rizwan Romee; Jianzhu Chen
err分享
err收藏
Tumor matrix directed IL12/A3 fusion cytokine secreted by CD70-CAR NK cells markedly enhances anti-ccRCC responses with limited systemic exposure肿瘤基质引导的IL12/A3融合细胞因子由CD70-CAR NK细胞分泌，可显著增强抗ccRCC反应，且全身暴露有限。
errONCOLOGIST
IF4.2
err2025-10-01
err0
errOAAI
errLiu, Fuguo; Deng, Xinyu; Nguyen, Maily; Tarannum, Mubin; Yang, Shaobo; Dulery, Remy; Chen, Jianzhu; Xu, Wenxin (Vincent); Choueri, Toni; Romee, Rizwan
err分享
err收藏
Lipid Nanoparticles Formulated with a Novel Cholesterol-Tailed Ionizable Lipid Markedly Increase mRNA Delivery Both in vitro and in vivo由一种新型胆固醇尾状可电离脂质配制的脂质纳米颗粒，显著提高了体内外的mRNA递送效率。
errInternational Journal of Nanomedicine
IF6.5
err2025-07-28
err0
errOAAI
errJu Hyeong Jeon; Huabin Zhu; Jane Qin; Luyao Wang; Stephanie Mou; Laura Katherine Langston; Ramesh Marasini; Jianzhu Chen; Renhuan Xu; Shuna Li; Xinle Cui
err分享
err收藏
Author Correction: Adhesive anti-fibrotic interfaces on diverse organs作者更正: 不同器官上的粘合剂抗纤维化界面
errNature
IF48.5
err2025-07-11
err0
errOAAI
errJingjing Wu; Jue Deng; Georgios Theocharidis; Tiffany L. Sarrafian; Leigh G. Griffiths; Roderick T. Bronson; Aristidis Veves; Jianzhu Chen; Hyunwoo Yuk; Xuanhe Zhao
err分享
err收藏
Membrane Expression Enhances Folding; Multimeric Structure Formation; and Immunogenicity of Viral Capsid Proteins膜表达增强了病毒衣壳蛋白的折叠、多聚体结构形成和免疫原性。
errACS Infectious Diseases
IF3.8
err2025-07-09
err0
errOAAI
errJunru Cui; Fangfeng Yuan; Jane Qin; Ju Hyeong Jeon; Dong Soo Yun; Tianlei Wang; Renhuan Xu; Hong Cao; Ashleigh A. Tungate; Christopher L. Netherton; Jianzhu Chen
err分享
err收藏
Engineering myeloid cells for cancer immunotherapy工程髓系细胞用于癌症免疫治疗
errCancer Cell
IF44.5
err2025-07-03
err0
PREAI
errJianzhu Chen; Yingjie Zhao; Xiaotong Chen; Jiayao Yan; Fuguo Liu; Rizwan Romee
err分享
err收藏
Selection; Design; and Immunogenicity Studies of ASFV Antigens for Subunit mRNA Cocktail Vaccines with Specific Immune Response Profiles筛选；设计；以及具有特定免疫反应谱的ASFV抗原亚单位mRNA鸡尾酒疫苗的免疫原性研究
errACS Infectious Diseases
IF3.8
err2025-06-06
err0
PREAI
errFangfeng Yuan; Junru Cui; Tianlei Wang; Jane Qin; Ju Hyeong Jeon; Huiming Ding; Charles A. Whittaker; Renhuan Xu; Hong Cao; Jianzhu Chen
err分享
err收藏
Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses
errNATURE BIOTECHNOLOGY
IF41.7
err2024-10-04
err1
PREAI
errYang, Shaobo; Sheffer, Michal; Kaplan, Isabel E.; Wang, Zongqi; Tarannum, Mubin; Dinh, Khanhlinh; Abdulhamid, Yasmin; Bobilev, Eden; Shapiro, Roman; Porter, Rebecca; Soiffer, Robert; Ritz, Jerome; Koreth, John; Wei, Yun; Chen, Peiru; Zhang, Ke; Marquez-Pellegrin, Valeria; Bonanno, Shanna; Joshi, Neel; Guan, Ming; Yang, Mengdi; Li, Deng; Bellini, Chiara; Liu, Fuguo; Chen, Jianzhu; Wu, Catherine J.; Barbie, David; Li, Jiahe; Romee, Rizwan
err分享
err收藏
CAR memory-like NK cells targeting the membrane proximal domain of mesothelin demonstrate promising activity in ovarian cancer
errSCIENCE ADVANCES
IF12.5
err2024-07-12
err2
errOAAI
errTarannum, Mubin; Dinh, Khanhlinh; Vergara, Juliana; Birch, Grace; Abdulhamid, Yasmin Z.; Kaplan, Isabel E.; Ay, Oyku; Maia, Andreia; Beaver, Owen; Sheffer, Michal; Shapiro, Roman; Ali, Alaa Kassim; Dong, Han; Ham, James Dongjoo; Bobilev, Eden; James, Sydney; Cameron, Amy B.; Nguyen, Quang-De; Ganapathy, Suthakar; Chayawatto, Chayapatou; Koreth, John; Paweletz, Cloud P.; Gokhale, Prafulla C.; Barbie, David A.; Matulonis, Ursula A.; Soiffer, Robert J.; Ritz, Jerome; Porter, Rebecca L.; Chen, Jianzhu; Romee, Rizwan
err分享
err收藏
Bosutinib Stimulates Macrophage Survival, Phagocytosis, and Intracellular Killing of Bacteria
errACS INFECTIOUS DISEASES
IF3.8
err2024-04-11
err2
errOAAI
errda Silva, Ronni A. G.; Stocks, Claudia J.; Hu, Guangan; Kline, Kimberly A.; Chen, Jianzhu
err分享
err收藏
NK and T cells armed with EVE16, a novel synthetic immune receptor, mediate robust anti-tumor responses through dual direct cytotoxicity and ADCC with minimal trogocytosis and exhaustion
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errAli, Alaa; Ham, James D.; Zairi, Faten; Patel, Vaishvi; Tarannum, Mubin; Khanhlinh Dinh; Abdulhamid, Yasmin; Vergara, Juliana; Soiffer, Robert; Ritz, Jerome; Beadle, John; Ivica, Nikola A.; Chen, Jianzhu; Romee, Rizwan
err分享
err收藏
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis
errNATURE COMMUNICATIONS
IF15.7
err2024-01-27
err4
errOAAI
errDong, Ting; Hu, Guangan; Fan, Zhongqi; Wang, Huirui; Gao, Yinghui; Wang, Sisi; Xu, Hao; Yaffe, Michael B.; Vander Heiden, Matthew G.; Lv, Guoyue; Chen, Jianzhu
err分享
err收藏
Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-12-22
err2
errOAAI
errYe, Zhongfeng; Bonam, Srinivasa Reddy; McKay, Lindsay G. A.; Plante, Jessica A.; Walker, Jordyn; Zhao, Yu; Huang, Changfeng; Chen, Jinjin; Xu, Chutian; Li, Yamin; Liu, Lihan; Harmon, Joseph; Gao, Shuliang; Song, Donghui; Zhang, Zhibo; Plante, Kenneth S.; Griffiths, Anthony; Chen, Jianzhu; Hu, Haitao; Xu, Qiaobing
err分享
err收藏
IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
errCELL REPORTS
IF6.9
err2023-08-01
err11
errOAAI
errPan, Li; Cho, Kin-Sang; Wei, Xin; Xu, Fuyi; Lennikov, Anton; Hu, Guangan; Tang, Jing; Guo, Shuai; Chen, Julie; Kriukov, Emil; Kyle, Robert; Elzaridi, Farris; Jiang, Shuhong; Dromel, Pierre A.; Young, Michael; Baranov, Petr; Do, Chi-Wai; Williams, Robert W.; Chen, Jianzhu; Lu, Lu; Chen, Dong Feng
err分享
err收藏
The T-cell receptor β variable gene promoter is required for efficient Vβ rearrangement but not allelic exclusion
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err38
errOAAI
errRyu, CJ; Haines, BB; Lee, HR; Kang, YH; Draganov, DD; Lee, MH; Whitehurst, CE; Hong, HJ; Chen, JZ
err分享
err收藏
Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err85
errOAAI
errWang, VEH; Schmidt, T; Chen, JZ; Sharp, PA; Tantin, D
err分享
err收藏
Mitoxantrone targets both host and bacteria to overcome vancomycin resistance in Enterococcus faecalis米托蒽醌靶向宿主和细菌以克服粪肠球菌对万古霉素的耐药性
errSCIENCE ADVANCES
IF12.5
err2023-02-24
err11
errOAAI
errda Silva, Ronni A. G.; Wong, Jun Jie; Antypas, Haris; Choo, Pei Yi; Goh, Karlyn; Jolly, Shreya; Liang, Cui; Sing, Leona Tay Kwan; Veleba, Mark; Hu, Guangan; Chen, Jianzhu; Kline, Kimberly A.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
R
Róbert Langer
H 指数: 262 · 论文数: 2.0K
N
Nicholas J. White
H 指数: 186 · 论文数: 2.0K
P
Phillip A. Sharp
H 指数: 173 · 论文数: 638
F
Frederick W. Alt
H 指数: 172 · 论文数: 637
T
Tyler Jacks
H 指数: 158 · 论文数: 818
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