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Alexander Muir

university of chicago
H指数:37
被引数:7,135

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工作经历

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荣誉奖项

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Mitochondrial one-carbon metabolism is required for TGF-β-induced glycine synthesis and fibrotic responses

线粒体一碳代谢对于TGF-β诱导的甘氨酸合成和纤维化反应是必需的。

Nature Communications
IF15.7
2025-10-200
OAAI
Angelo Y. Meliton; Kun Woo D. Shin; Rengül Cetin-Atalay; M. Volkan Atalay; Yufeng Tian; Jennifer C. Houpy Szafran; Takugo Cho; Kaitlyn A. Sun; Parker S. Woods; Obada R. Shamaa; Bohao Chen; Nickolai O. Dulin; Aliya N. Husain; Alexander Muir; Hardik Shah; Gökhan M. Mutlu; Robert B. Hamanaka
Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment

肿瘤相关巨噬细胞通过胶原沉积和乳腺癌微环境的代谢重编程限制CD8 T细胞功能

NATURE CANCER
IF28.5
2024-06-0312
PRE
Tharp, Kevin M.; Kersten, Kelly; Maller, Ori; Timblin, Greg A.; Stashko, Connor; Canale, Fernando P.; Menjivar, Rosa E.; Hayward, Mary-Kate; Berestjuk, Ilona; ten Hoeve, Johanna; Samad, Bushra; Ironside, Alastrair J.; di Magliano, Marina Pasca; Muir, Alexander; Geiger, Roger; Combes, Alexis J.; Weaver, Valerie M.
Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability

人类肾细胞癌的代谢物分析揭示了营养物质的组织来源优势

ELIFE
IF0
2024-05-244
OA
Abbott, Keene L.; Ali, Ahmed; Reinfeld, Bradley, I; Deik, Amy; Subudhi, Sonu; Landis, Madelyn D.; Hongo, Rachel A.; Young, Kirsten L.; Kunchok, Tenzin; Nabel, Christopher S.; Crowder, Kayla D.; Kent, Johnathan R.; Madariaga, Maria Lucia L.; Jain, Rakesh K.; Beckermann, Kathryn E.; Lewis, Caroline A.; Clish, Clary B.; Muir, Alexander; Rathmell, W. Kimryn; Rathmell, Jeffrey; Vander Heiden, Matthew G.
VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis

VHL损失重新编程免疫景观以促进肾脏肿瘤发生中的炎性髓样微环境

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-04-152
OAAI
Wolf, Melissa M.; Madden, Matthew Z.; Arner, Emily N.; Bader, Jackie E.; Ye, Xiang; Vlach, Logan; Tigue, Megan L.; Landis, Madelyn D.; Jonker, Patrick B.; Hatem, Zaid; Steiner, KayLee K.; Gaines, Dakim K.; Reinfeld, Bradley I.; Hathaway, Emma S.; Xin, Fuxue; Tantawy, M. Noor; Haake, Scott M.; Jonasch, Eric; Muir, Alexander; Weiss, Vivian L.; Beckermann, Kathryn E.; Rathmell, W. Kimryn; Rathmell, Jeffrey C.
Uridine- to-ribose axis supports glucose-restricted pancreatic cancer
CANCER RESEARCH
IF16.6
2024-01-160
PRE
Nwosu, Zeribe C.; Ward, Matthew H.; Sajjakulnukit, Peter; Poudel, Pawan; Ragulan, Chanthirika; Kasperek, Steven; Radyk, Megan; Sutton, Damien; Menjivar, Rosa E.; Andren, Anthony; Apiz-Saab, Juan J.; Tolstyka, Zachary; Brown, Kristee; Lee, Ho-Joon; Dzierozynski, Lindsey; He, Xi; Ps, Hari; Ugras, Julia; Nyamundanda, Gift; Zhang, Li; Halbrook, Christopher J.; Carpenter, Eileen; Shi, Jiaqi; Shriver, Leah P.; Patti, Gary J.; Muir, Alexander; di Magliano, Marina Pasca; Sadanandam, Anguraj; Lyssiotis, Costas A.
Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression

肿瘤外植体阐明了驱动胰腺癌血管抑制的旁分泌SHH，WNT和VEGF信号的级联

CANCER DISCOVERY
IF33.3
2023-11-144
OA
Hasselluhn, Marie C.; Decker-Farrell, Amanda R.; Vlahos, Lukas; Thomas, Dafydd H.; Curiel-Garcia, Alvaro; Maurer, H. Carlo; Wasko, Urszula N.; Tomassoni, Lorenzo; Sastra, Stephen A.; Palermo, Carmine F.; Dalton, Tanner C.; Ma, Alice; Li, Fangda; Tolosa, Ezequiel J.; Hibshoosh, Hanina; Fernandez-Zapico, Martin E.; Muir, Alexander; Califano, Andrea; Olive, Kenneth P.
Screening in serum-derived medium reveals differential response to compounds targeting metabolism
CELL CHEMICAL BIOLOGY
IF7.2
2023-09-0111
OAAI
Abbott, Keene L.; Ali, Ahmed; Casalena, Dominick; Do, Brian T.; Ferreira, Raphael; Cheah, Jaime H.; Soule, Christian K.; Deik, Amy; Kunchok, Tenzin; Schmidt, Daniel R.; Renner, Steffen; Honeder, Sophie E.; Wu, Michelle; Chan, Sze Ham; Tseyang, Tenzin; Stoltzfus, Andrew T.; Michel, Sarah L. J.; Greaves, Daniel; Hsu, Peggy P.; Ng, Christopher W.; Zhang, Chelsea J.; Farsidjani, Ali; Kent, Johnathan R.; Madariaga, Maria Lucia L.; Gramatikov, Iva Monique T.; Matheson, Nicholas J.; Lewis, Caroline A.; Clish, Clary B.; Rees, Matthew G.; Roth, Jennifer A.; Griner, Lesley Mathews; Muir, Alexander; Auld, Douglas S.; Heiden, Matthew G. Vander

研究方向

暂未获取到该数据
M
Matthew G. Vander Heiden
H 指数:119论文数:700被引数:9.1万
C
Caroline A. Lewis
H 指数:45论文数:138被引数:1.3万
J
Jeremy Thorner
H 指数:90论文数:272被引数:3.2万
F
Françoise M. Roelants
H 指数:15论文数:39被引数:1,517
P
Patrick B. Jonker
H 指数:6论文数:18被引数:242
C
Christopher J. Halbrook
H 指数:28论文数:146被引数:6,738
H
Hardik Shah
H 指数:32论文数:158被引数:7,744
C
Colin Sheehan
H 指数:7论文数:46被引数:392
R
Rosa E. Menjivar
H 指数:12论文数:100被引数:1,436
T
Tenzin Kunchok
H 指数:18论文数:57被引数:2,588