Sameer Aryal

broad institute of mit and harvard

H指数:11

被引数:2,446

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Srrm2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a genetic mouse model of schizophrenia

Srrm2功能缺失导致SynGAP-γ减少、Agap3错剪接及少突胶质细胞缺陷，在精神分裂症遗传小鼠模型中体现

Cell Reports

IF6.9

2026-05-250

OAAI

Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder

Akap11基因突变小鼠中升高的突触PKA活性和异常的纹状体多巴胺信号传导，这是一种精神分裂症和双相障碍的遗传模型。

Nature Communications

IF15.7

2025-11-280

OAAI

Bryan J. Song; Yang Ge; Ally Nicolella; Min Jee Kwon; Bart Lodder; Kevin Bonanno; Antia Valle-Tojeiro; Nolan D. Hartley; Kira Perzel Mandell; John Adeleye; Deeksha Misri; Chuhan Geng; Sahana Natarajan; Inès Picard; Nate Shepard; Alyssa Hall; Jiawen Tian; Sameer Aryal; Zohreh Farsi; Xiao-Man Liu; Nader Morshed; Naeem M. Nadaf; Horia Pribiag; Sean K. Simmons; D. R. Mani; Beth Stevens; Prabhat S. Kunwar; Zhanyan Fu; Evan Z. Macosko; Joshua Z. Levin; Bernardo L. Sabatini; Steven A. Carr; Borislav Dejanovic; Hasmik Keshishian; Adam J. Granger; Morgan Sheng

Meta-analysis of the brain transcriptomes of multiple genetic mouse models of schizophrenia highlights dysregulation in striatum and thalamus

精神分裂症多种遗传小鼠模型的脑转录组元分析强调了纹状体和丘脑的失调。

Translational Psychiatry

IF6.2

2025-09-290

OAAI

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice

NEURON

IF15

2023-11-0114