Tom Owen‐Hughes - Publications, H-index & Citations

Tom Owen‐Hughes

University of Dundee

61H指数

153论文数

1.4W被引数

收录论文 64

发表时间

RNA polymerase II promotes the organization of chromatin following DNA replication

EMBO REPORTS

IF6.2

2024-02-12

OAAI

Bandau, Susanne; Alvarez, Vanesa; Jiang, Hao; Graff, Sarah; Sundaramoorthy, Ramasubramanian; Gierlinski, Marek; Toman, Matt; Owen-Hughes, Tom; Sidoli, Simone; Lamond, Angus; Alabert, Constance

Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

127

OAAI

Barlev, NA; Poltoratsky, V; Owen-Hughes, T; Ying, C; Liu, L; Workman, JL; Berger, SL

Dynamic properties of nucleosomes during thermal and ATP-driven mobilization

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

104

OAAI

Flaus, A; Owen-Hughes, T

Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

166

OAAI

Whitehouse, I; Stockdale, C; Flaus, A; Szczelkun, MD; Owen-Hughes, T

Histone tails and the H3 αN helix regulate nucleosome mobility and stability

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

141

OAAI

Ferreira, Helder; Somers, Joanna; Webster, Ryan; Flaus, Andrew; Owen-Hughes, Tom

SWI/SNF and Asf1p Cooperate To Displace Histones during Induction of the Saccharomyces cerevisiae HO Promoter

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Gkikopoulos, Triantafyllos; Havas, Kristina M.; Dewar, Hilary; Owen-Hughes, Tom

Proteomic profiling reveals distinct phases to the restoration of chromatin following DNA replication

CELL REPORTS

IF6.9

2023-01-01

OAAI

Alvarez, Vanesa; Bandau, Susanne; Jiang, Hao; Rios-Szwed, Diana; Hukelmann, Jens; Garcia-Wilson, Elisa; Wiechens, Nicola; Griesser, Eva; Ten Have, Sara; Owen-Hughes, Tom; Lamond, Angus; Alabert, Constance

Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription SWI/SNF复合物的ARID1A亚基的急性耗竭揭示了转录激活和抑制的不同途径

CELL REPORTS

IF6.9

2021-11-01

OAAI

Blumli, Seraina; Wiechens, Nicola; Wu, Meng-Ying; Singh, Vijender; Gierlinski, Marek; Schweikert, Gabriele; Gilbert, Nick; Naughton, Catherine; Sundaramoorthy, Ramasubramanian; Varghese, Joby; Gourlay, Robert; Soares, Renata; Clark, David; Owen-Hughes, Tom

Histone isoforms and the oncohistone code

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2021-04-01

PREAI

Flaus, Andrew; Downs, Jessica A.; Owen-Hughes, Tom

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design (vol 15, pg 672, 2019)

NATURE CHEMICAL BIOLOGY

IF13.7

2019-07-02

OAAI

Farnaby, William; Koegl, Manfred; Roy, Michael J.; Whitworth, Claire; Diers, Emelyne; Trainor, Nicole; Zollman, David; Steurer, Steffen; Karolyi-Oezguer, Jale; Riedmueller, Carina; Gmaschitz, Teresa; Wachter, Johannes; Dank, Christian; Galant, Michael; Sharps, Bernadette; Rumpel, Klaus; Traxler, Elisabeth; Gerstberger, Thomas; Schnitzer, Renate; Petermann, Oliver; Greb, Peter; Weinstabl, Harald; Bader, Gerd; Zoephel, Andreas; Weiss-Puxbaum, Alexander; Ehrenhofer-Wolfer, Katharina; Wohrle, Simon; Boehmelt, Guido; Rinnenthal, Joerg; Arnhof, Heribert; Wiechens, Nicola; Wu, Meng-Ying; Owen-Hughes, Tom; Ettmayer, Peter; Pearson, Mark; McConnell, Darryl B.; Ciulli, Alessio

Structure-based PROTAC design demonstrates BAF complex ATPase vulnerabilities in cancer

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Koegl, Manfred; Farnaby, William; Whitworth, Claire; Roy, Michael; Diers, Emelyne; Trainor, Nicole; Steurer, Steffen; Riedmueller, Carina; Gmaschitz, Teresa; Wachter, Johannes; Dank, Christian; Gallant, Michael; Sharps, Bernadette; Rumpel, Klaus; Traxler, Elisabeth; Lorenz, Romario; Petermann, Oliver; Greb, Peter; Weinstabl, Harald; Bader, Gerd; Zoephel, Andreas; Weiss-Puxbaum, Alexander; Rinnenthal, Joerg; Arnnhof, Heribert; Wiechens, Nicola; Wu, Meng-Ying; Owen-Hughes, Tom; Ettmayer, Peter; Pearson, Mark; McConnell, Darryl B.; Ciulli, Alessio

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

NATURE CHEMICAL BIOLOGY

IF13.7

2019-06-10

381

OAAI

Farnaby, William; Koegl, Manfred; Roy, Michael J.; Whitworth, Claire; Diers, Emelyne; Trainor, Nicole; Zollman, David; Steurer, Steffen; Karolyi-Oezguer, Jale; Riedmueller, Carina; Gmaschitz, Teresa; Wachter, Johannes; Dank, Christian; Galante, Michael; Sharps, Bernadette; Rumpel, Klaus; Traxler, Elisabeth; Gerstberger, Thomas; Schnitzer, Renate; Petermann, Oliver; Grebe, Peter; Weinstabl, Harald; Bader, Gerd; Zoephel, Andreas; Weiss-Puxbaum, Alexander; Ehrenhoefer-Woelfer, Katharina; Woehrle, Simon; Boehmelt, Guido; Rinnenthal, Joerg; Arnhof, Heribert; Wiechens, Nicola; Wu, Meng-Ying; Owen-Hughes, Tom; Ettmayer, Peter; Pearson, Mark; McConnell, Darryl B.; Ciulli, Alessio

Identification of Elg1 interaction partners and effects on post-replication chromatin re- formation

PLOS GENETICS

IF3.7

2018-11-12

OAAI

Gali, Vamsi K.; Dickerson, David; Katou, Yuki; Fujiki, Katsunori; Shirahige, Katsuhiko; Owen-Hughes, Tom; Kubota, Takashi; Donaldson, Anne D.

Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC

ELIFE

IF0

2018-08-10

OAAI

Yoshikawa, Harunori; Larance, Mark; Harney, Dylan J.; Sundaramoorthy, Ramasubramanian; Ly, Tony; Owen-Hughes, Tom; Lamond, Angus I.

Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome

ELIFE

IF0

2018-08-06

OAAI

Sundaramoorthy, Ramasubramanian; Hughes, Amanda L.; El-Mkami, Hassane; Norman, David G.; Ferreira, Helder; Owen-Hughes, Tom

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes

ELIFE

IF0

2017-03-23

OAAI

Sunderamoothy, Ramsubramanian; Hughes, Amanda L.; Singh, Vijender; Wiechens, Nicola; Ryan, Daniel P.; El-Mkami, Hassane; Petoukhov, Maxim; Svergun, Dmitri I.; Terutlein, Barbara; Quack, Salina; Fisher, Monika; Michaelis, Jens; Bouttcher, Bettina; Norman, David G.; Owen-Hughes, Tom

Deciphering Subunit-Specific Functions within SWI/SNF Complexes

CELL REPORTS

IF6.9

2017-02-01

OAAI

Hughes, Amanda L.; Owen-Hughes, Tom

Unlocking the nucleosome

SCIENCE

IF45.8

2017-01-20

PREAI

Flaus, Andrew; Owen-Hughes, Tom

Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2017-01-09

185

OAAI

Hauer, Michael H.; Seeber, Andrew; Singh, Vijender; Thierry, Raphael; Sack, Ragna; Amitai, Assaf; Kryzhanovska, Mariya; Eglinger, Jan; Holcman, David; Owen-Hughes, Tom; Gasser, Susan M.

How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use? (vol 22, pg 839, 2016)

RNA

IF5

2016-09-16

OAAI

Schurch, Nicholas J.; Schofield, Pieta; Gierliniski, Marek; Cole, Christian; Sherstnev, Alexander; Singh, Vijender; Wrobel, Nicola; Gharbi, Karim; Simpson, Gordon G.; Owen-Hughes, Tom; Blaxter, Mark; Barton, Geoffrey J.

研究方向