An Open-Source Capping Machine Suitable for Confined Spaces

doi:10.1007/978-3-032-01486-3_35

2026-01-01

PRE

Francisco Munguia‐Galeano

Louis Longley

Satheeshkumar Veeramani

Zhengxue Zhou

Rob Clowes

Andrew I. Cooper *

DOI：10.1007/978-3-032-01486-3_35

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在自主驾驶实验室（SDLs）的背景下，确保自动化和无误的封盖至关重要，因为这是样品制备中一个普遍的步骤。SDLs中的自动化封盖可以发生在大型和小型工作空间（例如，在通风橱内）。然而，大多数商业封盖机主要设计用于大型空间，且通常过于笨重，不适合狭小环境。此外，许多商业产品是闭源的，这可能使其难以集成到完全自动化的工作流程中。本文介绍了一种适用于紧凑空间的开放式封盖机，该机器还集成了能够识别封盖失败的可视化系统。封盖和开盖过程各重复100次以验证机器的设计和性能。结果表明，封盖机在封盖和开盖方面均达到了100%的成功率。此外，通过封盖装有不同蒸气压溶剂（水、乙醇和丙酮）的12个样品瓶来评估机器的密封能力。随后，在三天内每隔3小时称重一次样品瓶。将该机器的性能与工业封盖机（Chemspeed工作站）和手动封盖进行基准比较。原型机封盖的样品瓶平均每天损失0.54%的重量，而使用Chemspeed和手动封盖的样品瓶分别损失0.0078%和0.013%。结果表明，该封盖机是工业和手动封盖的合理替代方案，尤其是在空间和预算有限制的情况下。

Keyword:

Chemistry Automation

Self-driving Laboratories

Capping

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TOWARDS AUTONOMOUS ROBOTIC SYSTEMS, TAROS 2025

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university of liverpool

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3.4K

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