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Curcumin-protein complexes: Technological and biological functionalities
DOI:10.1016/j.tifs.2024.104372.png)
摘要
En 中文
Background: Complexation with proteins has been employed as an efficient method to increase the solubility, stability, and bioavailability of curcumin (Cur) as a bioactive hydrophobic compound. Different animal (from milk, egg, meat, and insects) and plant proteins (from soy, pea, walnut, mung bean, corn, etc.) have been used to fabricate Cur -protein complexes (Cur -Pro). Scope and approach: This review mainly presents the technological and biological functionalities of Cur -Pro. Accordingly, the Cur -Pro prepared by different methods such as the simple complexation and pH -shifting approach were reviewed. This was followed by investigating the functional (interfacial activity, flow behavior, and gelation), bioactivity, release, and in vitro digestibility of the Cur -Pro. Key findings and conclusions: The results showed that Cur -Pro have excellent biological activities. Accordingly, the solvent -free pH -shifting approach was a more efficient method compared to the simple complexation to fabricate Cur -Pro. Also, the structural modification of proteins by different treatments e.g., aggregation (especially nanofibrillation), cross -linking, and ultrasonication can change their ability to form soluble complexes with Cur. The functional properties of Cur -Pro including rheological, gelation, and interfacial properties, show that the technological properties of proteins are modulated through complexation with Cur. Cur -Pro can protect Cur against the gastric digestion and provide a controlled -release in the intestinal phase. The in vitro digestibility of proteins in the simulated gastrointestinal conditions is influenced by Cur binding. Generally, Cur -Pro can be used as promising multi -functional ingredients to develop natural and safe functional foods for human health considerations.
Keyword:
Bioactive compounds
Hydrophobic interactions
Techno-functional properties
Antioxidant activity
Release behavior
期刊
T
IF:
15.4
论文数:
5.0K
被引数:
5.6W
机构
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