Exploring protein sequence-function landscapes

Tyler N. Starr

doi:10.1038/nbt.3786

2017-02-08

Tyler N. Starr

Joseph W. Thornton *

DOI：10.1038/nbt.3786

原文链接

查看原文

摘要

Keyword:

EPISTASIS

EVOLUTION

AI总结

对已上传原文的论文进行重点信息的提取，主要内容包括：简要概述、研究摘要、背景介绍、关键亮点、图文解析、展望与总结。

期刊

Nature Biotechnology

IF:

41.7

论文数:

1.2W

被引数:

10.1W

机构

university of chicago

学者数:

4.5W

论文数: 3.7W

被引数: 80

引用论文

Dynamics of functional networks for syllable and word-level processing

IF0

2019-03-21

OAAI

J.M. Rimmele; Y. Sun; G. Michalareas; O. Ghitza; D. Poeppel

Dobzhansky-Muller incompatibilities in protein evolution

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2002-10-28

265

OAAI

Kondrashov, AS; Sunyaev, S; Kondrashov, FA

Mutation effects predicted from sequence co-variation 从序列共变预测的突变效应

NATURE BIOTECHNOLOGY

IF41.7

2017-01-16

483

OAAI

Hopf, Thomas A.; Ingraham, John B.; Poelwijk, Frank J.; Scharfe, Charlotta P. I.; Springer, Michael; Sander, Chris; Marks, Debora S.

Coevolutionary Landscape Inference and the Context-Dependence of Mutations in Beta-Lactamase TEM-1

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2015-10-06

199

OAAI

Figliuzzi, Matteo; Jacquier, Herve; Schug, Alexander; Tenaillon, Oliver; Weigt, Martin

Should evolutionary geneticists worry about higher-order epistasis?

CURRENT OPINION IN GENETICS & DEVELOPMENT

IF3.6

2013-12-01

226

OAAI

Weinreich, Daniel M.; Lan, Yinghong; Wylie, C. Scott; Heckendorn, Robert B.

Deep mutational scanning: a new style of protein science 深度突变扫描: 蛋白质科学的新样式

NATURE METHODS

IF32.1

2014-07-30

858

OAAI

Fowler, Douglas M.; Fields, Stanley

European ADPKD Forum multidisciplinary position statement on autosomal dominant polycystic kidney disease care

Nephrology Dialysis Transplantation

IF0

2017-12-22

OAAI

Tess Harris; Richard Sandford; Brenda de Coninck; Olivier Devuyst; Joost P H Drenth; Tevfik Ecder; Alastair Kent; Ron T Gansevoort; José Luis Górriz; Albert C M Ong; Yves Pirson; Vicente E Torres; Klemens Budde; Denis Clément; Lorenzo E Derchi; Marianna Eleftheroudi; Elena Levtchenko; Dorien Peters; Hendrik Van Poppel; Raymond Vanholder

Predicting the effects of amino acid substitutions on protein function

annual review of genetics

IF7.9

2006-09-01

916

PREAI

Ng, Pauline C.; Henikoff, Steven

Emerging methods in protein co-evolution

NATURE REVIEWS GENETICS

IF52

2013-03-05

498

PREAI

de Juan, David; Pazos, Florencio; Valencia, Alfonso

Direct-coupling analysis of residue coevolution captures native contacts across many protein families 残基协同进化的直接耦合分析捕获了许多蛋白质家族的天然接触

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2011-11-21

1.1K

OAAI

Morcos, Faruck; Pagnani, Andrea; Lunt, Bryan; Bertolino, Arianna; Marks, Debora S.; Sander, Chris; Zecchina, Riccardo; Onuchic, Jose N.; Hwa, Terence; Weigt, Martin

没有更多内容