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Squidpy: a scalable framework for spatial omics analysis

delete2022-01-31
delete293
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OA
AI
G
Giovanni Palla
H
Hannah Spitzer
M
Michal Klein
D
David S. Fischer
A
Anna C. Schaar
L
Louis B. Kuemmerle
S
Sergei Rybakov
I
Ignacio L. Ibarra
O
Olle Holmberg
I
Isaac Virshup
M
Mohammad Lotfollahi
S
Sabrina Richter
F
Fabian J. Theis *
DOI:10.1038/s41592-021-01358-2delete
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Abstract

Abstract

En 中文
Spatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of spatial omics data. Here, we present Squidpy, a Python framework that brings together tools from omics and image analysis to enable scalable description of spatial molecular data, such as transcriptome or multivariate proteins. Squidpy provides efficient infrastructure and numerous analysis methods that allow to efficiently store, manipulate and interactively visualize spatial omics data. Squidpy is extensible and can be interfaced with a variety of already existing libraries for the scalable analysis of spatial omics data. Squidpy enables comprehensive analysis and visualization of spatial omics data and image with high efficiency.
Keywords:
GENE-EXPRESSION
VISUALIZATION
RESOLUTION
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Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Nature Methods cover
Nature Methods
IF:
32.1
Papers:
7.2K
Citations:
12.7W

Organization

H
Helmholtz Association
Scholars:
13.2W
Papers: 10.7W
Citations: 145