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FAIR Header Reference genome: a TRUSTworthy standard

delete2024-03-28
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OA
AI
A
Adam Wright *
M
Mark D. Wilkinson
M
Mungall, Christopher
S
Scott Cain
S
Stephen Richards
P
Paul W. Sternberg
E
Ellen Provin
J
Jonathan L. Jacobs
S
Scott M. Geib
D
Daniela Raciti
K
Karen Yook
L
Lincoln Stein
D
David Molik
DOI:10.1093/bib/bbae122delete
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Abstract

Abstract

En 中文
The lack of interoperable data standards among reference genome data-sharing platforms inhibits cross-platform analysis while increasing the risk of data provenance loss. Here, we describe the FAIR bioHeaders Reference genome (FHR), a metadata standard guided by the principles of Findability, Accessibility, Interoperability and Reuse (FAIR) in addition to the principles of Transparency, Responsibility, User focus, Sustainability and Technology. The objective of FHR is to provide an extensive set of data serialisation methods and minimum data field requirements while still maintaining extensibility, flexibility and expressivity in an increasingly decentralised genomic data ecosystem. The effort needed to implement FHR is low; FHR's design philosophy ensures easy implementation while retaining the benefits gained from recording both machine and human-readable provenance.
Keywords:
Reference Genome
provenance
data management
network effect
FASTA

Journal

Briefings in Bioinformatics cover
Briefings in Bioinformatics
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7.7
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5.6K
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Universidad Politecnica de Madrid
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Lawrence Berkeley National Laboratory
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united states department of energy (doe)
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Ontario Institute for Cancer Research
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university of toronto
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