Not logged in PKD1 and PKD2 mRNA cis-inhibition drives polycystic kidney disease progression Lakhia, Ronak; Ramalingam, Harini; Chang, Chun-Mien; Cobo-Stark, Patricia; Biggers, Laurence; Flaten, Andrea; Alvarez, Jesus; Valencia, Tania; Wallace, Darren P.; Lee, Edmund C.; Patel, Vishal Share Save
Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth Cao, Minghui; Isaac, Roi; Yan, Wei; Ruan, Xianhui; Jiang, Li; Wan, Yuhao; Wang, Jessica; Wang, Emily; Caron, Christine; Neben, Steven; Drygin, Denis; Pizzo, Donald P.; Wu, Xiwei; Liu, Xuxiang; Chin, Andrew R.; Fong, Miranda Y.; Gao, Ziting; Guo, Kaizhu; Fadare, Oluwole; Schwab, Richard B.; Yuan, Yuan; Yost, Susan E.; Mortimer, Joanne; Zhong, Wenwan; Ying, Wei; Bui, Jack D.; Sears, Dorothy D.; Olefsky, Jerrold M.; Wang, Shizhen Emily Share Save
Supporting US public health experts Cohen, Ron; Francois, Cedric; Crowley, John; Hastings, Paul; King, Rachel; Love, Ted W.; Maraganore, John; McMurry-Heath, Michelle; Levin, Jeremy; Adams, Chris; Al-Shamma, Sunny; Anderson, Bonnie; Anzalone, Christopher R.; Aspinall, Mara G.; Audia, James E.; Babler, Martin; Bacha, Jeffrey; Bailey, Michael P.; Bardon, Christiana; Barrett, Mark; Barrett, Peter; Becraft, Jacob; Bird, Jeffrey; Bitterman, Kevin; Blum, Robert; Bolno, Paul; Bonney, Michael; Booth, Bruce; Bosley, Katrine S.; Boyce, Sarah; Bozilenko, Marina; Burns, Jim; Byers, Brook; Cashman, John; Cayer, Devon; Chee, Brian; Clark, Chip; Cleland, Jeffrey; Coulter, Ivan; Cox, Gerald F.; Crane, Alan; Culley, Brian; Dabbagh, Karim; Dahiyat, Bassil; de Boer, Daniel A.; De Fougerolles, Tony; Deitcher, Steven R.; Demy, Sara Jane; Doerfler, Douglas; Dube, Eric; Earp, David J.; Ehrlich, Hartmut; Elms, Steve; Embury, Stephen H.; Epstein, David R.; Exter, Neil; Ezekowitz, Alan; Fambrough, Douglas; Farr, Stephen J.; Fetzer, Oliver; Forbes, Alexandria; Formela, J. F.; Foukes, Gordon; Fouse, Jackie; Fowler, John; Frank, Frederick; Ganot, Ilan; Gardner, Jason; Gibson, Christopher; Gorgas, Gregory; Graves, Kurt; Grayzel, David; Greene, Barry; Greenstreet, Yvonne; Gujrathi, Sheila; Haak-Frendscho, Mary; Hagan, John; Hallal, David; Hallam, Tom; Halloran, Laurie; Haseltine, William; Hasnain, Faheem; Heifetz, Peter B.; Hermiston, Terry; Herz, Jeffrey; Heyman, Richard; Holmlin, Erik; Hompesch, Marcus; Hutton, Wende; Ingram, Douglas S.; Johnson, John H.; Karsen, Perry; Kawahata, Douglas; Kaye, Edward M.; Kjellson, Nina; Ko Ferrigno, Paul; Krenn, Mike; Kriegsman, Steven; Kumar, Neil; LaMattina, John; Langer, Robert; Larwood, David; Lawrence, Matthew; Leerink, Jeff; Legoretta, Pablo; Leiden, Jeff; Leschly, Nick; Levin, Mark; Linthwaite, Christopher; Longman, Roger; Luderer, Albert; Macrae, Sandy; Mahmood, Tahi; Markus, Richard; Martin, Tyler; McCarthy, Sean; McCracken, Lee; McGuire, Terry; Mederis, Gail; Mackay, James; McMahon, Jerry; Milne, Jill C.; Miloni, Mauro; Moch, Kenneth I.; Mola, Paul; Monia, Brett; Moos, Walter; Morrison, Scott W.; Munshi, Amit; Murcko, Mark; Nashat, Amir; Newell, William J.; Nichtberger, Steven; Ors, Frederic; Papadopoulos, Stelios; Parker, H. Stewart; Parks, Elliot; Parmar, Kush M.; Payne, Joseph; Perry, Mark; Pfeffer, Cary G.; Polvino, William J.; Pruzanski, Mark; Purcell, Dennis J.; Pyott, David E. I.; Raab, Michael G.; Raythatha, Jigar; Register, R. Bruce; Renaud, Ronald, Jr.; Renton, Hollings; Rhodes, Christopher; Rhodes, Jason; Richman, Michael; Robin, Howard; Robbins, Wendye; Rutter, William J.; Sapirstein, James; Sato, Vicki; Sblendorio, Glenn; Scangos, George; Scarlett, John A.; Schiff, Drew; Schikan, Hans; Scibetta, James; Schulman, Amy; Scott, Tim; Sekhri, Paul; Seth, Alpna; Sherwin, Stephen A.; Short, Jay M.; Simon, Mark; Simonian, Nancy; Sinha, Vikas; Sivola, Tero; Slaoui, Moncef; Smith, Julie Anne; Smith, Erika R.; Sommadossi, Jean-Pierre; Soteropoulos, Paula; Souceck, Laura; Stiles, Travis; Stocks, Clifford J.; Stover, David; Suckow, Arthur; Szela, Mary T.; Tepper, Robert; Topol, Eric; Turenne, Andre; Velleca, Mark; Venkayya, Rajeev; Verdugo, Dawn; Walts, Alan; Wang, Bing; Warma, Neil; Wasserman, Scott; Ward, Robert; Webb, David; Weston, Claire; Westphal, Christoph; Wilson, James M.; Wilson, Mark S.; Winningham, Rick; You, Angie; Zakes, Bradford; Zerhouni, Elias A.; Zohar, Daphne; Zweifach, Sandy Share Save
Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease Lee, Edmund C.; Valencia, Tania; Allerson, Charles; Schairer, Annelie; Flaten, Andrea; Yheskel, Matanel; Kersjes, Kara; Li, Jian; Gatto, Sole; Takhar, Mandeep; Lockton, Steven; Pavlicek, Adam; Kim, Michael; Chu, Tiffany; Soriano, Randy; Davis, Scott; Androsavich, John R.; Sarwary, Salma; Owen, Tate; Kaplan, Julia; Liu, Kai; Jang, Graham; Neben, Steven; Bentley, Philip; Wright, Timothy; Patel, Vishal Share Save
microRNA-211 promotes aggressive melanoma growth in vivo by epigenetic modification, and contributes to BRAFV600E inhibitor resistance via ERK5 signaling Lee, Bongyong; Sahoo, Anupama; Sawada, Junko; Zisoulis, Dimitrios G.; Marchica, John; Sahoo, Sanjay; Layng, Fabiana I. Alves De Lima; Finlay, Darren; Mazar, Joseph; Joshi, Piyush; Komatsu, Masanobu; Vuori, Kristiina; Powis, Garth; de Jong, Petrus R.; Ray, Animesh; Perera, Ranjan J. Share Save
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Biotech leaders call for free press Cohen, Ron; Holtzman, Steven; Levin, Jeremy M.; Maraganore, John M.; Aberman, Michael; Adams, Chris; Adams, Julian; Albers, Jeffrey; Anderson, Bonnie; Aspinall, Mara G.; Audia, James E.; Babler, Martin; Baltimore, David; Bancel, Stephane; Barrett, Peter; Barry, Zoe; Bartel, David; Bienaime, Jean-Jacques; Blank, Burkhard; Blum, Robert I.; Bradbury, Daniel M.; Braunwald, Eugene; Butler, John P.; Carter, Bruce; Christensen, Gustav; Ciechanover, Isaac; Clark, Chip; Clarke, John K.; Clayman, Michael; Cleland, Jeffrey L.; Clem, David; Coles, N. Anthony; Cooney, Charles L.; Coughlin, Robert K.; Csimma, Zoltan; Curley, Sally J.; Dahiyat, Bassi; de Boer, Daniel A.; de los Piuos, Elisabet; DePinho, Ronald A.; Doerfler, Douglas; Dornbusch, Daniel; Douglas, Richard H.; Dunsire, Deborah; Exter, Neil; Farzan, Nina; Formela, Jean-Francois; Forrester, Robert; Franco, Maureen N.; Francois, Cedric; Franklin, Heather; Garland, Scott; Gill, Simba; Goeddel, David V.; Gowen, Maxine; Graves, Kurt; Gray, Mary Ann; Greene, Barry; Gros, David-Alexandre C.; Hasnain, Faheem; Hammerschmidt, Michael; Hawkins, Elma S.; Herndon, Russell; Hastings, Paul; Hindman, Andrew; Jenkins, Annalisa; Kadoch, Cigall; Kakkis, Emil D.; Kaplan, Johanne; Keating, Laurie; King, Rachel; King, Vanessa; Koenig, Scott; Kokhinsky, Peter; Koller, Daphne; Kozin, Marc; Laikind, Paul; Langer, Robert; La Voie, Donna L.; Lees, John J.; Leff's, Jonathan; Levy, Alan; Lieberman, Judy; Lindenboom, Christine; Liu, David R.; Lopatin, Uri; Love, Ted W.; Low, David N., Jr.; Malianthappa, Nagesh K.; Martignetti, Tiny; Martucci, W. Eddie; Mazitindar-Shaw, Kiran; McCain, Tracey L.; McCann, Corey M.; McLachlan, David J.; Meeker, David; Mehrotra, Ravi; Mentos, Steven I.; Meyers, Rachel; Miller, Gregory; Mills, Ken; Moch, Kenneth I.; Morrissey, Michael M.; Mulroy, Robert; Nasrullah, Hnran; Newell, William J.; Neylan, John F.; Olle, Bernat; Olson, Eric T.; Onsi, Douglas E.; Osborn, John E.; Owens, Julia C.; Papadopoulos, Stelios; Pau, Steve; Pereira, Brian J. G.; Peterkin, Doris; Pfeffer, Cary; Pruzanski, Mark.; Quirk, Gerald F.; Raab, Michael; Ragan, Paula; Rakhit, Amit; Rastetter, Bill; Renaud, Ron; Rhodes, Jason P.; Rocklage, Scott M.; Rosenblatt, Michael; Rutter, William J.; Samuels, Camille; Sapirstein, James; Sawhney, Amax; Scadden, David; Scangos, George; Scarlett, John A.; Schreiber, Stuart L.; Sekhri, Paul J.; Shaff, Eric; Shapiro, Bennett; Shenk, Thomas; Simonian, Nancy; Slattery, William; Smith, Erika R.; Steel, Bruce; Stock, Harald; Stocks, Clifford J.; Su, Michael; Surgenor, Tim; Tellier, Jean-Christophe; Theuer, Charles; Tolar, Martin; Tipol, Eric; Trehu, Beth; Vaishnaw, Akshay K.; van Heek, Christi; Vasconcelles, Michael J.; Vlasuk, George P.; Vounatsos, Michel; Walsh, Christopher T.; Wasman, Jane; Weisenfeld, Andrew; Werber, Yaron; Westphal, Christoph; Wierenga, Wendell; Winters, Thrry; Williams, Eugene; Witson, Chuck; Wirth, Peter; Xanthopoulos, Kleanthis; Zweifach, Sanford (Sandy) Share Save
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Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth Huang, Xinqiang; Magnus, Jill; Kaimal, Vivek; Karmali, Priya; Li, Jian; Walls, Marlena; Prudente, Rene; Sung, Eric; Sorourian, Mehran; Lee, Robin; Davis, Scott; Yang, Xia; Estrella, Heather; Lee, Edmund C.; Chau, B. Nelson; Pavlicek, Adam; Zabludoff, Sonya Share Save
Identification of metabolically stable 5′-phosphate analogs that support single-stranded siRNA activity (vol 43, pg 2993, 2015) Prakash, Thazha P.; Lima, Walt F.; Murray, Heather M.; Li, Wenyu; Kinberger, Garth A.; Chappell, Alfred E.; Gaus, Hans; Seth, Punit P.; Bhat, Balkrishen; Crooke, Stanley T.; Swayze, Eric E. Share Save
US immigration order strikes against biotech Levin, Jeremy M.; Holtzman, Steven H.; Maraganore, John; Hastings, Paul J.; Cohen, Ron; Dahiyat, Bassil; Adams, Julian; Adams, Chris; Ahrens, Brett; Albers, Jeff; Aspinall, Mara G.; Audia, James E.; Babler, Martin; Barrett, Peter; Barry, Zoe; Bermingham, Nessan; Blocha, Stephen; Blum, Robert I.; Bolno, Paul B.; Bonney, Michael W.; Booth, Bruce; Bradbury, Daniel M.; Brauer, Steven K.; Byers, Brook; Cagnoni, Pablo J.; Cali, Brian M.; Ciechanover, Isaac; Clark, Chip; Clayman, Michael D.; Cleland, Jeff L.; Cobb, Paula; Cooper, Ron; Currie, Mark G.; Diekman, John; Dobmeier, Eric L.; Doerfler, Doug; Donley, Elizabeth L. R.; Dunsire, Deborah; During, Matthew; Eckstein, Jens W.; Elenko, Eric; Exter, Neil A.; Fleming, Jonathan J.; Flesher, Gregory J.; Formela, Jean-Francois; Forrester, Robert; Francois, Cedric; Franklin, Heather; Freemana, Mason W.; Furst, Howard; Gage, Leonard Patrick; Galakatos, Nicholas; Gallagher, Brian M.; Geraghty, James A.; Gill, Simba; Goeddel, David V.; Goldsmith, Mark A.; Gowen, Maxine; Goyal, Vikas; Graney, Tom; Grayzel, David; Greene, Barry; Grint, Paul; Gutierrez-Ramos, J. C.; Haney, Bill; Tuan Ha-Ngoc; Harris, Tim; Hasnain, Faheem; Hata, Yujiro Steve; Hecht, Peter; Henshaw, Leslie; Heyman, Rich; Hoppenot, Herve; Horvitz, H. Robert; Hughes, Thomas E.; Hutton, Wende S.; Isaacs, Stephen T.; Jenkins, Annalisa; Jonker, Jeff; Kaplan, Jeff; Karsen, Perry; Keiper, Jeb; Kim, Jean; Kindler, Jeff; King, Rachel; King, Vanessa; Kjellson, Nina; Koenig, Scott; Koenig, Gerhard; Kolchinsky, Peter; Laikind, Paul; Langer, Robert (Bob); Lee, John J.; Leff, Jonathan S.; Leicher, Bruce A.; Leschly, Nick; Levin, Andrew; Levin, Mark; Levine, Arnold J.; Levy, Alan; Liu, David R.; Lodish, Harvey F.; Lopatin, Uri; Love, Ted W.; Macdonald, Guy; Maderis, Gail J.; Mahadevia, Ankit; Mahanthappa, Nagesh K.; Martin, Joel F.; Martin, Alex; Martucci, W. Eddie; McArthur, James G.; McCann, Corey M.; McCarthy, Sean A.; McDonough, C. Geoffrey; Mendlein, John; Miller, Larry; Miralles, Diego; Moch, Kenneth I.; More, Bob; Myers, Andrew G.; Narachi, Michael A.; Nashat, Amir; Nelson, Wendy; Newell, William J.; Olle, Bernat; Osborn, John E.; Owens, Julia C.; Pande, Atul; Papadopoulos, Stelios; Parker, H. Stewart; Parmara, Kush M.; Patterson, Matthew R.; Paul, Steve M.; Perez, Rob; Perry, Matthew; Pfeffer, Cary G.; Powell, Mike; Pruzanski, Mark; Purcell, Dennis J.; Rakhit, Amit; Ramamoorthi, Kartik; Rastetter, William; Rawcliffe, Adrian (Ad); Reid, Laurence E.; Renaud, Ron C.; Rhodes, Jason P.; Rieflin, William J.; Robins, Chad; Rocklageb, Scott M.; Rosenblatt, Michael; Rosin, Jonathan G.; Rutter, William J.; Saha, Saurabh; Samuels, Camille; Sato, Vicki L.; Scangos, George; Scarlett, John A.; Schenkein, David; Schreiber, Stuart L.; Schwabb, Andrew; Sekhri, Paul; Shah, Rajeev; Shenk, Thomas; Siegall, Clay B.; Simon, Nick J.; Simonian, Nancy; Stein, Jeff; Su, Michael; Szela, Mary T.; Taglietti, Marco; Tandon, Nina; Termeer, Henri; Thornberry, Nancy A.; Tolar, Martin; Ulevitchc, Richard; Vaishnaw, Akshay K.; VanLent, Anne; Varsavsky, Martin; Vlasuk, George P.; Vounatsos, Michel; Waksal, Samuel G.; Warma, Neil; Watts, Ryan J.; Werber, Yaron; Westphal, Christoph; Wierenga, Wendell; Williams, Doug E.; Williams, Lewis (Rusty); Xanthopoulos, Kleanthis G.; Zohar, Daphne; Zweifach, Sandford (Sandy) Share Save
MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels Nagarajan, Arvindhan; Petersen, Max C.; Nasiri, Ali R.; Butrico, Gina; Fung, Annie; Ruan, Hai-Bin; Kursawe, Romy; Caprio, Sonia; Thibodeau, Jacques; Bourgeois-Daigneault, Marie-Claude; Sun, Lisha; Gao, Guangping; Bhanot, Sanjay; Jurczak, Michael J.; Green, Michael R.; Shulman, Gerald I.; Wajapeyee, Narendra Share Save
Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss Arun, Gayatri; Diermeier, Sarah; Akerman, Martin; Chang, Kung-Chi; Wilkinson, J. Erby; Hearn, Stephen; Kim, Youngsoo; MacLeod, A. Robert; Krainer, Adrian R.; Norton, Larry; Brogi, Edi; Egeblad, Mikala; Spector, David L. Share Save
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Shift of microRNA profile upon orthotopic xenografting of glioblastoma spheroid cultures Halle, Bo; Thomassen, Mads; Venkatesan, Ranga; Kaimal, Vivek; Marcusson, Eric G.; Munthe, Sune; Sorensen, Mia D.; Aaberg-Jessen, Charlotte; Jensen, Stine S.; Meyer, Morten; Kruse, Torben A.; Christiansen, Helle; Schmidt, Steffen; Mollenhauer, Jan; Schulz, Mette K.; Andersen, Claus; Kristensen, Bjarne W. Share Save
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