logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
I

Ionis Pharmaceuticals Inc.

Scholars771
Papers481
Citations1
Related Papers (473)
Publication Date
delete
Neurodegenerative NMNAT2 Deficiency Promotes APP Processing in a SARM1-Dependent Manner
errCells
IF5.2
err2026-06-17
err0
errOAAI
errAndrea Enriquez; Sen Yang; Karen Ling; Paymaan Jafar-Nejad; Hui-Chen Lu
errShare
errSave
TGFβ activity stabilizes ACC1 to increase de novo lipogenesis in metabolic liver disease
errMolecular Metabolism
IF6.6
err2026-06-01
err0
errOAAI
errBrent Mayfield; Yoko Yagashita; Jinku Kang; Changyu Zhu; Stefania Mira; Timothy J. Kendall; Qiuyan Sun; Maria E. Meincke; Domenick Raphael; Meng Li; Shuxuan Chen; Harrison Cullen; Stryder M. Meadows; Luke E. Berchowitz; Michele Carrer; Jonathan A. Fallowfield; Robert F. Schwabe; Luca Valenti; Utpal B. Pajvani
errShare
errSave
Enhanced splicing modulation by NMA-modified antisense oligonucleotides
errNucleic Acids Research
IF13.1
err2026-05-21
err0
errOAAI
errKaren Ling; Thazha P Prakash; Jinghua Yu; Michaela Jackson; Seung J Chun; Gemma Bachmann; Noah Post; Sarah Greenlee; Armand Soriano; John L Hunyara; Daniel A Norris; Paymaan Jafar-nejad; Eric E Swayze; C Frank Bennett; Frank Rigo
errShare
errSave
Comparative Efficacy and Safety of Olezarsen Versus Plozasiran for Familial Chylomicronemia Syndrome: A Matching-Adjusted Indirect Comparison
errJournal of Clinical Lipidology
IF4.6
err2026-05-07
err0
errOAAI
errAsia Sikora Kessler; Paul Serafini; Divya Pushkarna; Mir-Masoud Pourrahmat; Seth J. Baum; Sotirios Tsimikas; Montserrat Vera Llonch
errShare
errSave
LncRNA-splicing factor condensates regulate hypoxia-responsive pre-mRNA processing near nuclear speckles
errMolecular Cell
IF16.6
err2026-03-19
err0
PREAI
errYou Jin Song; Min Kyung Shinn; Sushant Bangru; Yu Wang; Qinyu Sun; Qinyu Hao; Pankaj Chaturvedi; Susan M. Freier; Pablo Perez-Pinera; Erik R. Nelson; Andrew S. Belmont; Mitchell Guttman; Supriya G. Prasanth; Auinash Kalsotra; Rohit V. Pappu; Kannanganattu V. Prasanth
errShare
errSave
Impact of AGT rs5050(T>G) variants on associations between estradiol and angiotensinogen levels: Multi-Ethnic Study of Atherosclerosis (MESA)
errPLoS One
IF2.6
err2025-12-31
err0
PREAI
errLidani, Karita C. F.; Trainor, Patrick J.; Tomar, Shubham; Michos, Erin D.; Morgan, Erin S.; Rotter, Jerome I.; Guo, Xiuqing; Tsimikas, Sotirios; Defilippis, Andrew P.
errShare
errSave
Temporal Patterns of Triglyceride Testing and Test Results among Adults with Severe or Extreme Hypertriglyceridemia in US Clinical Practice
errAmerican Journal of Preventive Cardiology
IF5.9
err2025-11-20
err0
errOAAI
errAsia Sikora Kessler; Seth J. Baum; Emily Kutrieb; Montserrat Vera Llonch; Hongsheng Wu; Derek Weycker; Jonathan L. Respress; Daniel E. Soffer
errShare
errSave
Discovery of long-acting APOC3 siRNA for treating patients with hypertriglyceridemia
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-11-11
err0
PREAI
errPrakash, Thazha P.; Mullick, Adam E.; Riney, Stan; Yu, Jinghua; Nikan, Mehran; Quirk, Clare; Crutchfield, Amanda; Damle, Sagar S.; Klein, Stephanie; Swayze, Eric E.
errShare
errSave
Considerations for Microbiological Control Strategy during Oligonucleotide Drug Substance Manufacturing
errORGANIC PROCESS RESEARCH & DEVELOPMENT
IF3.5
err2025-11-01
err0
PREAI
errAllen, Deborah; Arts, Rick; Belin, Gamze; Borna, Mandana; Coffin, Chris; Drinkwater, Sophie; Jehle, Peter; Johnson, Joyce; Nuydens, Anja; Olbrich, Martin; Ortiz, Aura R.; Ozdemir, Mahir; Quinn, Andrew; Seyberth, Tobias; Smith, Peter D.; Tremmel, Sandra; Venkatram, Bharath; Willis, Jonathan
errShare
errSave
Accurate Mass Differences of High Molecular Weight Unknown Compounds from Resolved Isotopic Distributions: Oligonucleotide Impurities
errANALYTICAL CHEMISTRY
IF6.7
err2025-11-01
err0
PREAI
errRoussis, Stilianos G.
errShare
errSave
A Modeling Investigation of the CYP1A Drug Interactions of Riluzole
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2025-09-16
err0
errOAAI
errMalik, Paul; Mian, Paola; Andrews, Jinsy; Rosebraugh, Matthew; Ajroud-Driss, Senda
errShare
errSave
In PLN-R14del mice, SR structure restoration, rather than calcium cycling, is the dominant effector of PLN-ASO treatment
errCARDIOVASCULAR RESEARCH
IF13.3
err2025-09-01
err1
errOAAI
errSun, Liu; Eijgenraam, Tim R.; Amilon, Carl; Janzen, David; Hansson, Kenny M.; Kubli, Dieter A.; Spater, Daniela; Mullick, Adam E.; van der Meer, Peter; Teixeira, Vivian Oliveira Nunes; Sillje, Herman H. W.
errShare
errSave
Single alkyl phosphonate modification of the siRNA backbone in the seed region enhances specificity and therapeutic profile
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-08-12
err0
PREAI
errNikan, Mehran; Li, Qingfeng; Tanowitz, Michael; Li, Hongda; Damle, Sagar; Annoual, Marie; Galindo-Murillo, Rodrigo; Low, Audrey; Klein, Stephanie; Quirk, Clare; Vasquez, Guillermo; Wan, W. Brad; Watt, Andrew T.; Migawa, Michael T.; Swayze, Eric E.; Prakash, Thazha P.
errShare
errSave
Hepatocyte KCTD17-mediated SERPINA3 inhibition determines liver fibrosis in metabolic dysfunction-associated steatohepatitis
errExperimental & Molecular Medicine
IF12.9
err2025-08-01
err0
errOAAI
errYelin Jeong; Ah-Reum Oh; Young Hoon Jung; Kyung Hee Jung; Seongju Lee; Michele Carrer; Sang Bae Lee; Luca Valenti; Utpal B. Pajvani; KyeongJin Kim
errShare
errSave
Rates of acute pancreatitis and cardiovascular events among adults with severe or extreme hypertriglyceridemia in US clinical practice
errLipids in Health and Disease
IF4.2
err2025-07-30
err0
PREAI
errAsia Sikora Kessler; Seth J. Baum; Emily Kutrieb; Montserrat Vera Llonch; Alex Lonshteyn; Derek Weycker; Daniel E. Soffer
errShare
errSave
Effect of Olezarsen on Lipoprotein-Associated ApoC-III Levels in Patients with Familial Chylomicronemia Syndrome
errAtherosclerosis
IF5.7
err2025-07-21
err0
PREAI
errXiaohong Yang; Veronica J. Alexander; Shuting Xia; Sotirios Tsimikas
errShare
errSave
Antisense oligonucleotide therapy for patients with Friedreich’s ataxia carrying the c.165+5G>C splicing mutation
errMolecular Therapy Nucleic Acids
IF6.1
err2025-07-01
err0
errOAAI
errPouiré Yameogo; Selina Aguilar; Thazha P. Prakash; Frank Rigo; David R. Lynch; Jill S. Napierala; Marek Napierala
errShare
errSave
Distinct roles of the two BRCA2 DNA-binding domains in DNA damage repair and replication fork preservation
errCELL REPORTS
IF6.9
err2025-05-01
err0
errOAAI
errNeal, Francisco E.; Li, Wenjing; Uhrig, Mollie E.; Katz, Jeffrey N.; Syed, Shahrez; Sharma, Neelam; Dutta, Arijit; Burma, Sandeep; Hromas, Robert; Mazin, Alexander, V; Dray, Eloise; Libich, David S.; Olsen, Shaun K.; Wasmuth, Elizabeth, V; Zhao, Weixing; Sorensen, Claus S.; Wiese, Claudia; Kwon, Youngho; Sung, Patrick
errShare
errSave
The differential impact of HNRNPA1 isoforms on gene expression and their relevance to dsRNA-mediated innate immune response
errSCIENTIFIC REPORTS
IF3.9
err2025-05-01
err0
errOAAI
errDeshaies, Jade-Emmanuelle; Triassi, Valerie; Lacombe, Andreanne; Gagne, Myriam; Ling, Karen; Ghosh, Asmita; Labrecque, Marjorie; Rigo, Frank; Jafar-nejad, Paymaan; Tetreault, Martine; Velde, Christine Vande
errShare
errSave
Skeletal muscle effects of antisense oligonucleotides targeting glycogen synthase 1 in a mouse model of Pompe disease
errCLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
err2025-04-23
err0
errOAAI
errWeiss, Lan; Carrer, Michele; Shmara, Alyaa; Martin, Angela; Yin, Hong; Pal, Pallabi; Cheng, Cheng; Ta, Lac; Boock, Victoria; Fazeli, Yasamin; Chang, Mindy; Paguio, Marvin; Lee, Jonathan; Yu, Howard; Weiss, John; Grossman, Tamar R.; Raben, Nina; Jafar-Nejad, Paymaan; Kimonis, Virginia
errShare
errSave