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Costas D. Maranas

pennsylvania state university

82H-index
378Paper Count
2.2WCitation Count
Published Papers 176
Publication Date
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BindPred: A Framework for Predicting Protein-Protein Binding Affinity from Language Model Embeddings
errBioinformatics
IF5.4
err2026-05-14
err0
errOAAI
errHaixing Piao; Veda Sheersh Boorla; Somtirtha Santra; Costas D Maranas; null
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MechFind: a computational framework for de novo prediction of enzyme mechanisms
errNature Communications
IF15.7
err2026-04-29
err0
errOAAI
errAustin D. Hartley; Vikas Upadhyay; Veda Sheersh Boorla; Costas D. Maranas
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errSave
High yield production of 3-hydroxypropionic acid using Issatchenkia orientalis
errNature Communications
IF15.7
err2026-01-09
err0
errOAAI
errShih-I Tan; Sarang S. Bhagwat; Teresa A. Martin; Patrick F. Suthers; Vinh G. Tran; Wuying Tang; Zia Fatma; Costas D. Maranas; Jeremy S. Guest; Huimin Zhao
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errSave
Building an expanded bio-based economy through synthetic biology
errBiotechnology Advances
IF12.5
err2025-12-06
err0
PREAI
errAndrea M. Garza Elizondo; Ilenne Del Valle Kessra; Erica Teixeira Prates; Evan Komp; Elise K. Phillips; Nandhini Ashok; Daniel A. Jacobson; Erin G. Webb; Yannick J. Bomble; William G. Alexander; Joanna Tannous; Chung-Jui Tsai; Wayne A. Parrott; Xiaohan Yang; Breeanna R. Urbanowicz; Laura E. Bartley; Costas D. Maranas; Gerald A. Tuskan; Adam M. Guss; Carrie A. Eckert
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errSave
Metabolic flux and resource balance in the oleaginous yeast Rhodotorula toruloides
errMetabolic Engineering
IF6.8
err2025-12-01
err0
PREAI
errEric J. Mooney; Patrick F. Suthers; Wheaton L. Schroeder; Hoang V. Dinh; Xi Li; Yihui Shen; Tianxia Xiao; Catherine M. Call; Heide Baron; Arjuna M. Subramanian; Daniel R. Weilandt; Felix C. Keber; Martin Wühr; Joshua D. Rabinowitz; Costas D. Maranas
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errSave
Parameterization of cell-free systems with time-series data using KETCHUP
errPLOS COMPUTATIONAL BIOLOGY
IF3.6
err2025-11-01
err0
PREAI
errHu, Mengqi; Jilani, Syed Bilal; Olson, Daniel G.; Maranas, Costas D.
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Reconstruction of a resource balance analysis model of Clostridium thermocellum examines the metabolic cost of glycolytic and cellulosome enzymes
errMetabolic Engineering
IF6.8
err2025-09-08
err0
PREAI
errThomas C. Willis; Wheaton L. Schroeder; Daven B. Khana; Xuejun Qian; Sanjeev Dahal; Daniel Amador-Noguez; Costas D. Maranas
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errSave
Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid
errACS SYNTHETIC BIOLOGY
IF3.9
err2025-03-01
err0
PREAI
errUpadhyay, Vikas; Li, Hongxiang; He, Jiachen; Ocampo, Blake Edward; Cook, Silas; Zhao, Huimin; Maranas, Costas D.
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errSave
minChemBio: Expanding Chemical Synthesis with Chemo-Enzymatic Pathways Using Minimal Transitions
errACS SYNTHETIC BIOLOGY
IF3.9
err2025-02-14
err0
errOAAI
errAnand, Mohit; Upadhyay, Vikas; Maranas, Costas D.
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errSave
Current State, Challenges, and Opportunities in Genome-Scale Resource Allocation Models: A Mathematical Perspective
errMETABOLITES
IF3.7
err2024-06-28
err3
errOAAI
errSchroeder, Wheaton L.; Suthers, Patrick F.; Willis, Thomas C.; Mooney, Eric J.; Maranas, Costas D.
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errSave
Dehydrated Biomimetic Membranes with Skinlike Structure and Function
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2024-04-10
err1
PREAI
errOh, Hyeonji; Tu, Yu-Ming; Samineni, Laximicharan; De Respino, Sophie; Mehrafrooz, Behzad; Joshi, Himanshu; Massenburg, Lynnicia; Lopez-Marques, Horacio; Elessawy, Nada; Song, Woochul; Behera, Harekrushna; Dhiman, Raman; Boorla, Veda Sheersh; Kher, Kartik; Lin, Yi-Chih; Maranas, Costas; Aksimentiev, Aleksei; Freeman, Benny D.; Kumar, Manish
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errSave
Data-driven and physics informed modeling of Chinese Hamster Ovary cell bioreactors
errCOMPUTERS & CHEMICAL ENGINEERING
IF3.9
err2024-04-01
err4
PREAI
errCui, Tianqi; Bertalan, Tom; Ndahiro, Nelson; Khare, Pratik; Betenbaugh, Michael; Maranas, Costas; Kevrekidis, Ioannis G.
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errSave
Genome streamlining to improve performance of a fast-growing cyanobacterium Synechococcus elongatus UTEX 2973
errMBIO
IF4.7
err2024-03-13
err9
errOAAI
errSengupta, Annesha; Bandyopadhyay, Anindita; Sarkar, Debolina; Hendry, John I.; Schubert, Max G.; Liu, Deng; Church, George M.; Maranas, Costas D.; Pakrasi, Himadri B.
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errSave
Mitochondrial ATP generation is more proteome efficient than glycolysis
errNATURE CHEMICAL BIOLOGY
IF13.7
err2024-03-06
err12
PREAI
errShen, Yihui; Dinh, Hoang V.; Cruz, Edward R.; Chen, Zihong; Bartman, Caroline R.; Xiao, Tianxia; Call, Catherine M.; Ryseck, Rolf-Peter; Pratas, Jimmy; Weilandt, Daniel; Baron, Heide; Subramanian, Arjuna; Fatma, Zia; Wu, Zong-Yen; Dwaraknath, Sudharsan; Hendry, John I.; Tran, Vinh G.; Yang, Lifeng; Yoshikuni, Yasuo; Zhao, Huimin; Maranas, Costas D.; Wuehr, Martin; Rabinowitz, Joshua D.
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errSave
KETCHUP: Parameterizing of large-scale kinetic models using multiple datasets with different reference states
errMETABOLIC ENGINEERING
IF6.8
err2024-03-01
err1
PREAI
errHu, Mengqi; Suthers, Patrick F.; Maranas, Costas D.
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errSave
Deuterated water as a substrate-agnostic isotope tracer for investigating reversibility and thermodynamics of reactions in central carbon metabolism
errMETABOLIC ENGINEERING
IF6.8
err2023-11-01
err2
errOAAI
errCallaghan, Melanie M.; Thusoo, Eashant; Sharma, Bishal D.; Getahun, Fitsum; Stevenson, David M.; Maranas, Costas; Olson, Daniel G.; Lynd, Lee R.; Amador-Noguez, Daniel
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errSave
A single amino acid change led to structural and functional differentiation of PvHd1 to control flowering in switchgrass
errJOURNAL OF EXPERIMENTAL BOTANY
IF5.7
err2023-07-04
err4
errOAAI
errChoi, Soyeon; Prabhakar, Pradeep K.; Chowdhury, Ratul; Pendergast IV, Thomas H.; Urbanowicz, Breeanna R.; Maranas, Costas; Devos, Katrien M.
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errSave
Rank-ordering of known enzymes as starting points for re-engineering novel substrate activity using a convolutional neural network
errMETABOLIC ENGINEERING
IF6.8
err2023-07-01
err7
errOAAI
errUpadhyay, Vikas; Boorla, Veda Sheersh; Maranas, Costas D.
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errSave
Metabolic engineering of low-pH-tolerant non-model yeast, Issatchenkia orientalis, for production of citramalate
errmetabolic engineering
IF4.1
err2023-06-01
err12
errOAAI
errWu, Zong-Yen; Sun, Wan; Shen, Yihui; Pratas, Jimmy; Suthers, Patrick F.; Hsieh, Ping-Hung; Dwaraknath, Sudharsan; Rabinowitz, Joshua D.; Maranas, Costas D.; Shao, Zengyi; Yoshikuni, Yasuo
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errSave
A detailed genome-scale metabolic model of Clostridium thermocellum investigates sources of pyrophosphate for driving glycolysis
errMETABOLIC ENGINEERING
IF6.8
err2023-05-01
err8
errOAAI
errSchroeder, Wheaton L.; Kuil, Teun; van Maris, Antonius J. A.; Lynd, Lee R.; Maranas, Costas D.
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errSave

Research Directions

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Co-authors
Cooperation Journals
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Frank J. Gonzalez
H-index: 191 · Papers: 1.7K
B
Bernhard Ø. Palsson
H-index: 166 · Papers: 1.2K
J
Jens Nielsen
H-index: 161 · Papers: 1.5K
K
Klaus Schulten
H-index: 145 · Papers: 718
R
Richard A. Dixon
H-index: 140 · Papers: 551
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