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Brigitta Loretz

helmholtz center for infection research (hzi) and helmholtz institute for pharmaceutical research saarland (hips)

36H-index
137Paper Count
4.7KCitation Count
Published Papers 85
Publication Date
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Accelerated Mucopermeation and Penetration of the Polypeptide Antibiotic Colistin via Ionic Complexation with Polyphosphazene Carriers
errACS Omega
IF4.3
err2026-05-01
err0
errOAAI
errPauline Stadler; Stefanie Kehrer; Paul Strasser; Cornelia Roschger; Brigitta Loretz; Ian Teasdale
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A multivalent TAT–arginine-biodynamer conjugate targeting the bacterial cell envelope via specific membrane interactions
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-04-02
err0
errOAAI
errMohamed A.M. Kamal; Walaa M. Metwally; Justine Bassil; Bart-Jan Niebuur; Tobias Kraus; Jennifer Herrmann; Marcus Koch; Anna K.H. Hirsch; Brigitta Loretz; Sangeun Lee; Claus-Michael Lehr
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Staphylococcal proliferation on skin models to investigate novel anti-infective treatments against dysbiosis
errBioengineering & Translational Medicine
IF5.7
err2026-03-26
err0
errOAAI
errSarah Frisch; Samy Aliyazdi; Jacqueline Rehner; Georges Schmartz; Caroline Gevaerd; Lorenz Latta; Barbara Veldung; Sören L. Becker; Andreas Keller; Ulrich F. Schaefer; Brigitta Loretz; Thomas Vogt; Claus-Michael Lehr
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Multiparameter Optimization of Pseudomonas aeruginosa Elastase Inhibitors for Systemic Administration
errJournal of Medicinal Chemistry
IF6.8
err2026-02-05
err0
errOAAI
errAhmed S. Abdelsamie; Jelena Konstantinović; Andreas M. Kany; Christian Schütz; Dominik Kolling; Samira Speicher; Andreas Klein; Roya Shafiei; Mélodie Bouté; Katharina Mundry; Yu Mi Park; Brigitta Loretz; Rolf Müller; Jean-Michel Sallenave; Claus-Michael Lehr; Jesko Koehnke; Katharina Rox; Jörg Haupenthal; Anna K. H. Hirsch
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Toward Anti-Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen
errCHEMMEDCHEM
IF3.4
err2025-11-01
err0
errOAAI
errBerwanger, Aylin; Stein, Saskia Catherina; Brandner, Sarah; Kany, Andreas Martin; Heinz, Sebastian; Loretz, Brigitta; Lehr, Claus-michael; Hirsch, Anna Katharina Herta; Lermyte, Frederik; Schulz, Thomas Friedrich; Empting, Martin
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Soft Mist Inhaler Nebulization by Rayleigh-breakup Largely Preserves Functional Integrity of Liposomal mRNA in Respirable Aerosols
errEuropean Journal of Pharmaceutical Sciences
IF4.7
err2025-09-28
err0
errOAAI
errAchim Biesel; Sabine Maamari; Nils Salaw; Imco Sibum; Nicolas Buchmann; Brigitta Loretz; Elisabeth M. Zeisberg; Claus-Michael Lehr
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Exploring the future of mRNA delivery: Beyond lipid nanoparticles
errBiochemical and Biophysical Research Communications
IF2.2
err2025-07-14
err0
errOAAI
errAljoscha Gabelmann; Achim Biesel; Brigitta Loretz; Claus-Michael Lehr
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Tobramycin crosslinking improves the colloidal stability of arginine chitosan biodynamers for safe and efficient siRNA delivery
errINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
IF8.5
err2025-06-01
err0
PREAI
errLiu, Yun; Biesel, Achim; Kamal, Mohamed A. M.; Latta, Lorenz; Loretz, Brigitta; Hirsch, Anna K. H.; Lee, Sangeun; Lehr, Claus-Michael
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A novel lipopolyplex platform for dual mRNA delivery via core- and surface-loading
errJournal of Controlled Release
IF11.5
err2025-05-22
err0
errOAAI
errAljoscha Gabelmann; Elham Mansouri-Ghahnavieh; Marcus Koch; Prashant Shinde; Carlos A. Guzmán; Brigitta Loretz; Claus-Michael Lehr
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Antimicrobial and antibiotic-potentiating effect of calcium peroxide nanoparticles on oral bacterial biofilms
errNPJ BIOFILMS AND MICROBIOMES
IF9.2
err2024-10-15
err0
errOAAI
errBankar, Neha; Latta, Lorenz; Loretz, Brigitta; Reda, Bashar; Dudek, Johanna; Haehl, Hendrik; Hannig, Matthias; Lehr, Claus-Michael
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The HIPS 2024 symposium: highlighting advances in pharmaceutical sciences in infection research
errTRENDS IN MICROBIOLOGY
IF14.9
err2024-10-01
err0
PREAI
errMayoka, Godfrey; Krug, Daniel; Loretz, Brigitta; Bozhueyuek, Kenan; Empting, Martin; Hirsch, Anna K. H.; Mueller, Rolf
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A stretchable human lung-on-chip model of alveolar inflammation for evaluating anti-inflammatory drug response
errBIOENGINEERING & TRANSLATIONAL MEDICINE
IF5.7
err2024-09-05
err0
errOAAI
errRichter, Clementine; Latta, Lorenz; Harig, Daria; Carius, Patrick; Stucki, Janick D.; Hobi, Nina; Hugi, Andreas; Schumacher, Paul; Krebs, Tobias; Gamrekeli, Alexander; Stoeckle, Felix; Urbschat, Klaus; Montalvo, Galia; Lautenschlaeger, Franziska; Loretz, Brigitta; Hidalgo, Alberto; Schneider-Daum, Nicole; Lehr, Claus-Michael
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Nanoparticles in liposomes: a platform for increased antibiotic selectivity in multidrug resistant bacteria in respiratory tract infections
errDRUG DELIVERY AND TRANSLATIONAL RESEARCH
IF5.5
err2024-07-24
err0
errOAAI
errFakhoury, Nathalie E.; Mansour, Samar; Abdel-Halim, Mohammad; Hamed, Mostafa M.; Empting, Martin; Boese, Annette; Loretz, Brigitta; Lehr, Claus-Michael; Tammam, Salma N.
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Realizing time-staggered expression of nucleic acid-encoded proteins by co-delivery of messenger RNA and plasmid DNA on a single nanocarrier
errDRUG DELIVERY AND TRANSLATIONAL RESEARCH
IF5.5
err2024-07-15
err2
PREAI
errNasr, Sarah S.; Paul, Pascal; Loretz, Brigitta; Lehr, Claus-Michael
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A Novel 3D Printed Model of Infected Human Hair Follicles to Demonstrate Targeted Delivery of Nanoantibiotics
errACS BIOMATERIALS SCIENCE & ENGINEERING
IF5.5
err2024-07-04
err1
errOAAI
errAliyazdi, Samy; Frisch, Sarah; Neu, Tobias; Veldung, Barbara; Karande, Pankaj; Schaefer, Ulrich F.; Loretz, Brigitta; Vogt, Thomas; Lehr, Claus-Michael
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Biodynamer Nano-Complexes and -Emulsions for Peptide and Protein Drug Delivery
errINTERNATIONAL JOURNAL OF NANOMEDICINE
IF6.5
err2024-05-01
err1
errOAAI
errLiu, Yun; Hamm, Timo; Eichinger, Thomas Ralf; Kamm, Walter; Wieland, Heike Andrea; Loretz, Brigitta; Hirsch, Anna K. H.; Lee, Sangeun; Lehr, Claus -Michael
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Targeting Intracellular Bacteria with Dual Drug-loaded Lactoferrin Nanoparticles
errACS INFECTIOUS DISEASES
IF3.8
err2024-04-05
err4
errOAAI
errAndima, Moses; Boese, Annette; Paul, Pascal; Koch, Marcus; Loretz, Brigitta; Lehr, Claus-Micheal
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Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
errACS CENTRAL SCIENCE
IF10.4
err2023-10-27
err7
errOAAI
errKonstantinovic, Jelena; Kany, Andreas M.; Alhayek, Alaa; Abdelsamie, Ahmed S.; Sikandar, Asfandyar; Voos, Katrin; Yao, Yiwen; Andreas, Anastasia; Shafiei, Roya; Loretz, Brigitta; Schoenauer, Esther; Bals, Robert; Brandstetter, Hans; Hartmann, Rolf W.; Ducho, Christian; Lehr, Claus-Michael; Beisswenger, Christoph; Mueller, Rolf; Rox, Katharina; Haupenthal, Joerg; Hirsch, Anna K. H.
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pH-Responsive Dynaplexes as Potent Apoptosis Inductors by Intracellular Delivery of Survivin siRNA
errBIOMACROMOLECULES
IF5.4
err2023-07-31
err5
PREAI
errLiu, Yun; Ashmawy, Salma; Latta, Lorenz; Weiss, Agnes-Valencia; Kiefer, Alexander F.; Nasr, Sarah; Loretz, Brigitta; Hirsch, Anna K. H.; Lee, Sangeun; Lehr, Claus-Michael
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Disrupting Kaposi's Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-07-28
err3
errOAAI
errBerwanger, Aylin; Stein, Saskia C.; Kany, Andreas M.; Gartner, Melissa; Loretz, Brigitta; Lehr, Claus-Michael; Hirsch, Anna K. H.; Schulz, Thomas F.; Empting, Martin
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Research Directions

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Co-authors
Cooperation Journals
K
Klaus H. Kaestner
H-index: 126 · Papers: 602
M
Matthias Schwab
H-index: 122 · Papers: 1.4K
顾
顾臻 (Zhen Gu)
H-index: 120 · Papers: 516
P
Patrick Couvreur
H-index: 118 · Papers: 753
C
Claus‐Michael Lehr
H-index: 95 · Papers: 629
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