Not logged inEngineered IscB-WRNA system with improved base editing efficiency for disease correction via single AAV delivery in mice
Guo, Ruochen; Sun, Xiaozhi; Wang, Feizuo; Han, Dingyi; Yang, Qiaoxia; Gao, Hua; Li, Zhifang; Shao, Zhuang; Shi, Jinqi; Yang, Rongrong; Huo, Xiaona; Yan, Junda; Li, Guoling; Xiao, Qingquan; Liu, Yuanhua; Zhang, Senfeng; Liu, Xinyu; Zhou, Yingsi; Wang, Leyun; Hu, Chunyi; Xu, Chunlong .png)
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SaveEngineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation (vol 15, 8090, 2024)Li, Guoling; Dong, Xue; Luo, Jiamin; Yuan, Tanglong; Li, Tong; Zhao, Guoli; Zhang, Hainan; Zhou, Jingxing; Zeng, Zhenhai; Cui, Shuna; Wang, Haoqiang; Wang, Yin; Yu, Yuyang; Yuan, Yuan; Zuo, Erwei; Xu, Chunlong; Huang, Jinhai; Zhou, Yingsi Share Save Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitationLi, Guoling; Dong, Xue; Luo, Jiamin; Yuan, Tanglong; Li, Tong; Zhao, Guoli; Zhang, Hainan; Zhou, Jingxing; Zeng, Zhenhai; Cui, Shuna; Wang, Haoqiang; Wang, Yin; Yu, Yuyang; Yuan, Yuan; Zuo, Erwei; Xu, Chunlong; Huang, Jinhai; Zhou, Yingsi Share Save Repurposing Type I-A CRISPR-Cas3 for a robust diagnosis of human papillomavirus (HPV)Hu, Tao; Ji, Quanquan; Ke, Xinxin; Zhou, Hufeng; Zhang, Senfeng; Ma, Shengsheng; Yu, Chenlin; Ju, Wenjun; Lu, Meiling; Lin, Yu; Ou, Yangjing; Zhou, Yingsi; Xiao, Yibei; Xu, Chunlong; Hu, Chunyi Share Save Development of deaminase-free T-to-S base editor and C-to-G base editor by engineered human uracil DNA glycosylaseTong, Huawei; Wang, Haoqiang; Wang, Xuchen; Liu, Nana; Li, Guoling; Wu, Danni; Li, Yun; Jin, Ming; Li, Hengbin; Wei, Yinghui; Li, Tong; Yuan, Yuan; Shi, Linyu; Yao, Xuan; Zhou, Yingsi; Yang, Hui Share Save Engineering a transposon-associated TnpB-ωRNA system for efficient gene editing and phenotypic correction of a tyrosinaemia mouse modelLi, Zhifang; Guo, Ruochen; Sun, Xiaozhi; Li, Guoling; Shao, Zhuang; Huo, Xiaona; Yang, Rongrong; Liu, Xinyu; Cao, Xi; Zhang, Hainan; Zhang, Weihong; Zhang, Xiaoyin; Ma, Shuangyu; Zhang, Meiling; Liu, Yuanhua; Yao, Yinan; Shi, Jinqi; Yang, Hui; Hu, Chunyi; Zhou, Yingsi; Xu, Chunlong Share Save Enhanced C-To-T and A-To-G Base Editing in Mitochondrial DNA with Engineered DdCBE and TALEDWei, Yinghui; Jin, Ming; Huang, Shuhong; Yao, Fangyao; Ren, Ningxin; Xu, Kun; Li, Shangpu; Gao, Pengfei; Zhou, Yingsi; Chen, Yulin; Yang, Hui; Li, Wen; Xu, Chunlong; Zhang, Meiling; Wang, Xiaolong Share Save In vivo treatment of tyrosinaemia with hypercompact Cas12f1Guo, Ruochen; Li, Zhifang; Li, Guoling; Zhang, Hainan; Zhang, Chang; Huo, Xiaona; Zhang, Xiaoyin; Yang, Xiali; Yang, Rongrong; Liu, Yuanhua; Sun, Xiaozhi; Liu, Xinyu; Yang, Hui; Zhou, Yingsi; Xu, Chunlong Share Save Development of miniature base editors using engineered IscB nickaseHan, Dingyi; Xiao, Qingquan; Wang, Yifan; Zhang, Hainan; Dong, Xue; Li, Guoling; Kong, Xiangfeng; Wang, Shihao; Song, Jinhui; Zhang, Weihong; Zhou, Jingxing; Bi, Lanting; Yuan, Yuan; Shi, Linyu; Zhong, Na; Yang, Hui; Zhou, Yingsi Share Save Programmable deaminase-free base editors for G-to-Y conversion by engineered glycosylaseTong, Huawei; Liu, Nana; Wei, Yinghui; Zhou, Yingsi; Li, Yun; Wu, Danni; Jin, Ming; Cui, Shuna; Li, Hengbin; Li, Guoling; Zhou, Jingxing; Yuan, Yuan; Zhang, Hainan; Shi, Linyu; Yao, Xuan; Yang, Hui Share Save Develop a Compact RNA Base Editor by Fusing ADAR with Engineered EcCas6eWang, Xing; Zhang, Renxia; Yang, Dong; Li, Guoling; Fan, Zhanqing; Du, Hongting; Wang, Zikang; Liu, Yuanhua; Lin, Jiajia; Wu, Xiaoqing; Shi, Linyu; Yang, Hui; Zhou, Yingsi Share Save Engineered CRISPR-OsCas12f1 and RhCas12f1 with robust activities and expanded target range for genome editingKong, Xiangfeng; Zhang, Hainan; Li, Guoling; Wang, Zikang; Kong, Xuqiang; Wang, Lecong; Xue, Mingxing; Zhang, Weihong; Wang, Yao; Lin, Jiajia; Zhou, Jingxing; Shen, Xiaowen; Wei, Yinghui; Zhong, Na; Bai, Weiya; Yuan, Yuan; Shi, Linyu; Zhou, Yingsi; Yang, Hui Share Save An engineered xCas12i with high activity, high specificity, and broad PAM rangeZhang, Hainan; Kong, Xiangfeng; Xue, Mingxing; Hu, Jing; Wang, Zikang; Wei, Yinghui; Wang, Haoqiang; Zhou, Jingxing; Zhang, Weihong; Xu, Mengqiu; Shen, Xiaowen; Yin, Fengcai; Ai, Zhiyuan; Huang, Guangyan; Xia, Junhui; Song, Xueqiong; Li, Hengbin; Yuan, Yuan; Li, Jinhui; Zhong, Na; Zhang, Meiling; Zhou, Yingsi; Yang, Hui Share Save Human 8-cell embryos enable efficient induction of disease-preventive mutations without off-target effect by cytosine base editorWei, Yinghui; Zhang, Meiling; Hu, Jing; Zhou, Yingsi; Xue, Mingxing; Yin, Jianhang; Liu, Yuanhua; Feng, Hu; Zhou, Ling; Li, Zhifang; Wang, Dongshuang; Zhang, Zhiguo; Zhou, Yin; Liu, Hongbin; Yao, Ning; Zuo, Erwei; Hu, Jiazhi; Du, Yanzhi; Li, Wen; Xu, Chunlong; Yang, Hui Share Save High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effectsTong, Huawei; Huang, Jia; Xiao, Qingquan; He, Bingbing; Dong, Xue; Liu, Yuanhua; Yang, Xiali; Han, Dingyi; Wang, Zikang; Ying, Wenqin; Zhang, Runze; Wei, Yu; Wang, Xuchen; Xu, Chunlong; Zhou, Yingsi; Li, Yanfei; Cai, Minqing; Wang, Qifang; Xue, Mingxing; Li, Guoling; Fang, Kailun; Zhang, Hainan; Yang, Hui Share Save Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbes (vol 18, pg 499, 2021)Xu, Chunlong; Zhou, Yingsi; Xiao, Qingquan; He, Bingbing; Geng, Guannan; Wang, Zikang; Cao, Birong; Dong, Xue; Bai, Weiya; Wang, Yifan; Wang, Xiang; Zhou, Dongming; Yuan, Tanglong; Huo, Xiaona; Lai, Jinsheng; Yang, Hui Share Save Share Save Programmable RNA editing with compact CRISPR-Cas13 systems from uncultivated microbesXu, Chunlong; Zhou, Yingsi; Xiao, Qingquan; He, Bingbing; Geng, Guannan; Wang, Zikang; Cao, Birong; Dong, Xue; Bai, Weiya; Wang, Yifan; Wang, Xiang; Zhou, Dongming; Yuan, Tanglong; Huo, Xiaona; Lai, Jinsheng; Yang, Hui Share Save Indiscriminate ssDNA cleavage activity of CRISPR-Cas12a induces no detectable off-target effects in mouse embryosWei, Yu; Zhou, Yingsi; Liu, Yajing; Ying, Wenqin; Lv, Ruiming; Zhao, Qimeng; Zhou, Haibo; Zuo, Erwei; Sun, Yidi; Yang, Hui; Zhou, Changyang Share Save Endogenous promoter-driven sgRNA for monitoring the expression of low-abundance transcripts and lncRNAsGao, Ni; Hu, Jing; He, Bingbing; Ji, Zhengbang; Hu, Xinde; Huang, Jia; Wei, Yu; Peng, Jianpeng; Wei, Yinghui; Zhou, Yingsi; Shen, Xiaowen; Li, He; Feng, Xue; Xiao, Qingquan; Shi, Linyu; Sun, Yidi; Zhou, Changyang; Zhou, Haibo; Yang, Hui Share Save 
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