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R

Ron O. Dror

department of computer science

91H-index
360Paper Count
4.8WCitation Count
Published Papers 83
Publication Date
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Structural basis of opioid receptor activation by PCP and ketamine
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2026-06-22
err0
errOAAI
errQianru Jiang; Jianming Han; Eve J. Fine; Nokomis Ramos-Gonzalez; Vipin Ashok Rangari; Micaela V. Ruiz; Madalyn L. Critz; Carl-Mikael Suomivuori; Jing Wang; Talia L. Albert; Kyle Whiddon; Kunpeng Li; Michael J. Robertson; Xi-Ping Huang; Benjamin B. Land; Susruta Majumdar; Jonathan F. Fay; Ron O. Dror; Tao Che
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Structural dynamics of kappa opioid receptor interactions with β-arrestin 1
errNature Communications
IF15.7
err2026-06-04
err0
errOAAI
errJianming Han; Eve J. Fine; Qianru Jiang; Yuxuan Zhuang; Carl-Mikael Suomivuori; Zi-Wei Chen; Elizabeth Denn; Kyle Whiddon; Kunpeng Li; Alex S. Evers; James Fuller; Joshua Carter; Jonathan F. Fay; Muyuan Chen; Ron O. Dror; Tao Che
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Structural insights into coffee bitter taste perception by TAS2R43 receptor
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2026-04-20
err0
errOAAI
errYoojoong Kim; Ryan H. Gumpper; Yuxuan Zhuang; Ron O. Dror; Bryan L. Roth
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Molecular mechanism of exchange coupling in CLC chloride/proton antiporters
errNature Communications
IF15.7
err2026-01-08
err0
errOAAI
errDeniz Aydin; Chih-Ta Chien; Jürgen Kreiter; Amy R. Nava; Jasmina M. Portasikova; Lukas Fojtik; Briana L. Sobecks; Catalina Mosquera; Petr Man; Ron O. Dror; Wah Chiu; Merritt Maduke
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Protein Structural Model Selection Informed by Comparison of Predicted Ligand Binding Poses
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-11-01
err0
PREAI
errKarelina, Masha; Dror, Ron O.
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errSave
Structure and mechanism of the mitochondrial calcium transporter NCLX
errNature
IF48.5
err2025-09-10
err0
errOAAI
errMinrui Fan; Chen-Wei Tsai; Jinru Zhang; Jianxiu Zhang; Aswini R. Krishnan; Tsung-Yun Liu; Yu-Lun Huang; Deniz Aydin; Siyuan Du; Briana L. Sobecks; Madison X. Rodriguez; Andrew H. Reiter; Carolyn R. Bertozzi; Ron O. Dror; Ming-Feng Tsai; Liang Feng
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errSave
The polypharmacology of psychedelics reveals multiple targets for potential therapeutics
errNeuron
IF15
err2025-07-18
err0
PREAI
errManish K. Jain; Ryan H. Gumpper; Samuel T. Slocum; Gavin P. Schmitz; Jakob S. Madsen; Tia A. Tummino; Carl-Mikael Suomivuori; Xi-Ping Huang; Laura Shub; Jeffrey F. DiBerto; Kuglae Kim; Chelsea DeLeon; Brain E. Krumm; Jonathan F. Fay; Michael Keiser; Alexander S. Hauser; Ron O. Dror; Brian Shoichet; David E. Gloriam; David E. Nichols; Bryan L. Roth
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errSave
Targeting a Cryptic Pocket in Cannabinoid Receptor 1 Drives Peripheral and Functional Selectivity
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errMajumdar, Susruta; Rangari, Vipin; Gereau, Robert W.; Dror, Ron; Kumar, Kaavya Krishna; O'Brien, Evan; Slivicki, Richard; Powers, Alexander S.
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Systematic analysis of biomolecular conformational ensembles with PENSA
errJOURNAL OF CHEMICAL PHYSICS
IF3.1
err2025-01-02
err2
PREAI
errVogele, Martin; Thomson, Neil J.; Truong, Sang T.; Mcavity, Jasper; Zachariae, Ulrich; Dror, Ron O.
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errSave
RNA-Puzzles Round V: blind predictions of 23 RNA structures
errNATURE METHODS
IF32.1
err2024-12-02
err0
errOAAI
errBu, Fan; Adam, Yagoub; Adamiak, Ryszard W.; Antczak, Maciej; de Aquino, Belisa Rebeca H.; Badepally, Nagendar Goud; Batey, Robert T.; Baulin, Eugene F.; Boinski, Pawel; Boniecki, Michal J.; Bujnicki, Janusz M.; Carpenter, Kristy A.; Chacon, Jose; Chen, Shi-Jie; Chiu, Wah; Cordero, Pablo; Das, Naba Krishna; Das, Rhiju; Dawson, Wayne K.; Dimaio, Frank; Ding, Feng; Dock-Bregeon, Anne-Catherine; Dokholyan, Nikolay V.; Dror, Ron O.; Dunin-Horkawicz, Stanislaw; Eismann, Stephan; Ennifar, Eric; Esmaeeli, Reza; Farsani, Masoud Amiri; Ferre-D'Amare, Adrian R.; Geniesse, Caleb; Ghanim, George E.; Guzman, Horacio V.; Hood, Iris V.; Huang, Lin; Jain, Dharm Skandh; Jaryani, Farhang; Jin, Lei; Joshi, Astha; Karelina, Masha; Kieft, Jeffrey S.; Kladwang, Wipapat; Kmiecik, Sebastian; Koirala, Deepak; Kollmann, Markus; Kretsch, Rachael C.; Kurcinski, Mateusz; Li, Jun; Li, Shuang; Magnus, Marcin; Masquida, Benoit; Moafinejad, S. Naeim; Mondal, Arup; Mukherjee, Sunandan; Nguyen, Thi Hoang Duong; Nikolaev, Grigory; Nithin, Chandran; Nye, Grace; Pandaranadar Jeyeram, Iswarya P. N.; Perez, Alberto; Pham, Phillip; Piccirilli, Joseph A.; Pilla, Smita Priyadarshini; Pluta, Radoslaw; Poblete, Simon; Ponce-Salvatierra, Almudena; Popenda, Mariusz; Popenda, Lukasz; Pucci, Fabrizio; Rangan, Ramya; Ray, Angana; Ren, Aiming; Sarzynska, Joanna; Sha, Congzhou Mike; Stefaniak, Filip; Su, Zhaoming; Suddala, Krishna C.; Szachniuk, Marta; Townshend, Raphael; Trachman III, Robert J.; Wang, Jian; Wang, Wenkai; Watkins, Andrew; Wirecki, Tomasz K.; Xiao, Yi; Xiong, Peng; Xiong, Yiduo; Yang, Jianyi; Yesselman, Joseph David; Zhang, Jinwei; Zhang, Yi; Zhang, Zhenzhen; Zhou, Yuanzhe; Zok, Tomasz; Zhang, Dong; Zhang, Sicheng; Zyla, Adriana; Westhof, Eric; Miao, Zhichao
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A non-canonical mechanism of GPCR activation
errNATURE COMMUNICATIONS
IF15.7
err2024-11-16
err0
errOAAI
errPowers, Alexander S.; Khan, Aasma; Paggi, Joseph M.; Latorraca, Naomi R.; Souza, Sarah; Di Salvo, Jerry; Lu, Jun; Soisson, Stephen M.; Johnston, Jennifer M.; Weinglass, Adam B.; Dror, Ron O.
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The Art and Science of Molecular Docking
errANNUAL REVIEW OF BIOCHEMISTRY
IF20.5
err2024-08-02
err21
PREAI
errPaggi, Joseph M.; Pandit, Ayush; Dror, Ron O.
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errSave
Signaling Modulation Mediated by Ligand Water Interactions with the Sodium Site at μOR
errACS CENTRAL SCIENCE
IF10.4
err2024-07-17
err2
errOAAI
errOple, Rohini S.; Ramos-Gonzalez, Nokomis; Li, Qiongyu; Sobecks, Briana L.; Aydin, Deniz; Powers, Alexander S.; Faouzi, Abdelfattah; Polacco, Benjamin J.; Bernhard, Sarah M.; Appourchaux, Kevin; Sribhashyam, Sashrik; Eans, Shainnel O.; Tsai, Bowen A.; Dror, Ron O.; Varga, Balazs R.; Wang, Haoqing; Huttenhain, Ruth; McLaughlin, Jay P.; Majumdar, Susruta
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CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism
errELIFE
IF0
err2024-02-12
err1
errOAAI
errXu, Mengyuan; Neelands, Torben; Powers, Alexander S.; Liu, Yan; Miller, Steven D.; Pintilie, Grigore D.; Du Bois, J.; Dror, Ron O.; Chiu, Wah; Maduke, Merritt
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GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-02-07
err4
errOAAI
errHoppe, Nicholas; Harrison, Simone; Hwang, Sun-Hee; Chen, Ziwei; Karelina, Masha; Deshpande, Ishan; Suomivuori, Carl-Mikael; Palicharla, Vivek R.; Berry, Samuel P.; Tschaikner, Philipp; Regele, Dominik; Covey, Douglas F.; Stefan, Eduard; Marks, Debora S.; Reiter, Jeremy F.; Dror, Ron O.; Evers, Alex S.; Mukhopadhyay, Saikat; Manglik, Aashish
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How accurately can one predict drug binding modes using AlphaFold models?
errELIFE
IF0
err2023-12-22
err34
errOAAI
errKarelina, Masha; Noh, Joseph J.; Dror, Ron O.
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errSave
Geometric Deep Learning for Structure-Based Ligand Design
errACS CENTRAL SCIENCE
IF10.4
err2023-11-17
err11
errOAAI
errPowers, Alexander S.; Yu, Helen H.; Suriana, Patricia; Koodli, Rohan V.; Lu, Tianyu; Paggi, Joseph M.; Dror, Ron O.
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errSave
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR
errNATURE COMMUNICATIONS
IF15.7
err2023-09-06
err10
errOAAI
errBurger, Wessel A. C.; Pham, Vi; Vuckovic, Ziva; Powers, Alexander S.; Mobbs, Jesse I.; Laloudakis, Yianni; Glukhova, Alisa; Wootten, Denise; Tobin, Andrew B.; Sexton, Patrick M.; Paul, Steven M.; Felder, Christian C.; Danev, Radostin; Dror, Ron O.; Christopoulos, Arthur; Valant, Celine; Thal, David M.
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A positively tuned voltage indicator for extended electrical recordings in the brain
errNATURE METHODS
IF32.1
err2023-07-06
err23
errOAAI
errEvans, S. Wenceslao; Shi, Dong-Qing; Chavarha, Mariya; Plitt, Mark H.; Taxidis, Jiannis; Madruga, Blake; Fan, Jiang Lan; Hwang, Fuu-Jiun; van Keulen, Siri C.; Suomivuori, Carl-Mikael; Pang, Michelle M.; Su, Sharon; Lee, Sungmoo; Hao, Yukun A.; Zhang, Guofeng; Jiang, Dongyun; Pradhan, Lagnajeet; Roth, Richard H.; Liu, Yu; Dorian, Conor C.; Reese, Austin L.; Negrean, Adrian; Losonczy, Attila; Makinson, Christopher D.; Wang, Sui; Clandinin, Thomas R.; Dror, Ron O.; Ding, Jun B.; Ji, Na; Golshani, Peyman; Giocomo, Lisa M.; Bi, Guo-Qiang; Lin, Michael Z.
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How ligands achieve biased signaling at opioid receptors
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err0
errOAAI
errPaggi, Joseph M.; Aydin, Deniz; Laloudakis, Yianni D.; Suomivuori, Carl-Mikael; Che, Tao; Dror, Ron O.
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Research Directions

No research directions
Co-authors
Cooperation Journals
C
Carolyn R. Bertozzi
H-index: 140 · Papers: 942
B
Brian K. Kobilka
H-index: 140 · Papers: 519
B
Bryan L. Roth
H-index: 139 · Papers: 970
N
Nevan J. Krogan
H-index: 129 · Papers: 747
W
William F. DeGrado
H-index: 124 · Papers: 758
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