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William J. Polacheck

University of North Carolina School of Medicine

29H-index
97Paper Count
5.5KCitation Count
Published Papers 44
Publication Date
A novel manganese glycerophosphate vaccine gel elicits broad and durable immunity across an aged and pox virus model
err2026-04-01
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errIslam, Md Jahirul; Ontiveros-Padilla, Luis; Ehrenzeller, Stephen A.; Middleton, Denzel D.; Roque, John A.; Murphy, Connor T.; Lukesh, Nicole Rose; Hendy, Dylan A.; Pena, Erik S.; Stack, Ryan N.; Polacheck, William J.; Bachelder, Eric M.; Ainslie, Kristy M.
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The Notch1 intracellular domain orchestrates mechanotransduction of fluid shear stress
err2026-02-05
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PREAI
errSingh, Tania; Jacobs, Kyle A.; Polacheck, William J.; Kutys, Matthew L.
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Functional analysis of TWIST1 domains regulating smooth muscle cell phenotype
err2025-10-31
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errDanielle C. M. Dy; Thiel Lehman; Adrian Othon; Mitesh Rathod; William J. Polacheck; Robert Wirka
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Endothelial-smooth muscle microgauges for modeling pulmonary arterial vasoregulation
err2025-10-14
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errAanya Sawhney; Raymond Piatt; Miitesh Rathod; Ryan Stack; Chloe Whitworth; William Polacheck
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Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction
err2025-06-20
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errMitesh Rathod; Ryan N. Stack; Sarah E. Kubik; Stephanie A. Huang; Chloe P. Whitworth; Wen Y. Aw; Elizabeth L. Doherty; Sara M. Meehan; Prabir Roy-Chaudhury; William J. Polacheck
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Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations
err2025-02-05
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errAw, Wen Yih; Sawhney, Aanya; Rathod, Mitesh; Whitworth, Chloe P.; Doherty, Elizabeth L.; Madden, Ethan; Lu, Jingming; Westphal, Kaden; Stack, Ryan; Polacheck, William J.
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Understanding the Lymphatic System: Tissue-on-Chip Modeling
err2025-01-22
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PREAI
errPolacheck, William J.; Dixon, J. Brandon; Aw, Wen Yih
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Magnetically Integrated Tumor-Vascular Interface System to Mimic Pro-angiogenic Endothelial Dysregulations for On-Chip Drug Testing
err2024-08-28
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errSurendran, Vikram; Safarulla, Simrit; Griffith, Christian; Ali, Reem; Madan, Ankit; Polacheck, William; Chandrasekaran, Arvind
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Direct conversion of cardiac fibroblasts into endothelial-like cells using Sox17 and Erg
err2024-05-16
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errFarber, Gregory; Dong, Yanhan; Wang, Qiaozi; Rathod, Mitesh; Wang, Haofei; Dixit, Michelle; Keepers, Benjamin; Xie, Yifang; Butz, Kendall; Polacheck, William J.; Liu, Jiandong; Qian, Li
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Human Cell-Derived Matrix Composite Hydrogels with Diverse Composition for Use in Vasculature-on-chip Models
err2024-04-02
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PREAI
errDoherty, Elizabeth L.; Krohn, Grace; Warren, Emily C.; Patton, Alexandra; Whitworth, Chloe P.; Rathod, Mitesh; Biehl, Andreea; Aw, Wen Yih; Freytes, Donald O.; Polacheck, William J.
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Donor-Derived Engineered Microvessels for Cardiovascular Risk Stratification of Patients with Kidney Failure
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IF12.1
err2024-01-07
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errRathod, Mitesh L.; Aw, Wen Yih; Huang, Stephanie; Lu, Jingming; Doherty, Elizabeth L.; Whithworth, Chloe P.; Xi, Gang; Roy-Chaudhury, Prabir; Polacheck, William J.
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A nanoporous hydrogel-based model to study chemokine gradient-driven angiogenesis under luminal flow
err2024-01-01
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errMote, Nidhi; Kubik, Sarah; Polacheck, William J.; Baker, Brendon M.; Trappmann, Britta
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Human vascularized bile duct-on-a chip: a multi-cellular micro-physiological system for studying cholestatic liver disease
err2023-10-20
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errDu, Yu; de Jong, Iris E. M.; Gupta, Kapish; Waisbourd-Zinman, Orit; Har-Zahav, Adi; Soroka, Carol J.; Boyer, James L.; Llewellyn, Jessica; Liu, Chengyang; Naji, Ali; Polacheck, William J.; Wells, Rebecca G.
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A 3D biomimetic model of lymphatics reveals cell-cell junction tightening and lymphedema via a cytokine- induced ROCK2/JAM-A complex
err2023-10-02
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errLee, Esak; Chan, Siu-Lung; Lee, Yang; Polacheck, William J.; Kwak, Sukyoung; Wen, Aiyun; Nguyen, Duc- Huy T.; Kutys, Matthew L.; Alimperti, Stella; Kolarzyk, Anna M.; Kwak, Tae Joon; Eyckmans, Jeroen; Bielenberg, Diane R.; Chen, Hong; Chen, Christopher S.
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Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics
err2023-08-01
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errOAAI
errDoherty, Elizabeth L.; Aw, Wen Yih; Warren, Emily C.; Hockenberry, Max; Whitworth, Chloe P.; Krohn, Grace; Howell, Stefanie; Diekman, Brian O.; Legant, Wesley R.; Nia, Hadi Tavakoli; Hickey, Anthony J.; Polacheck, William J.
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Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation
err2023-02-17
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errAw, Wen Yih; Cho, Crescentia; Wang, Hao; Cooper, Anne Hope; Doherty, Elizabeth L.; Rocco, David; Huang, Stephanie A.; Kubik, Sarah; Whitworth, Chloe P.; Armstrong, Ryan; Hickey, Anthony J.; Griffith, Boyce; Kutys, Matthew L.; Blatt, Julie; Polacheck, William J.
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A vascularized model of the human liver mimics regenerative responses
err2022-06-28
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errChhabra, Arnav; Song, H-H Greco; Grzelak, Katarzyna A.; Polacheck, William J.; Fleming, Heather E.; Chen, Christopher S.; Bhatia, Sangeeta N.
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Multilayer microfluidic platform for the study of luminal, transmural, and interstitial flow
err2022-01-25
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errLee, Gi-hun; Huang, Stephanie A.; Aw, Wen Y.; Rathod, Mitesh L.; Cho, Crescentia; Ligler, Frances S.; Polacheck, William J.
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