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John L. Rubinstein

the hospital for sick children and the university of toronto

55H-index
284Paper Count
2.1WCitation Count
Published Papers 97
Publication Date
Structure-guided design of a synthetic bile acid that inhibits Clostridioides difficile TcdB toxin
err2025-11-18
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PREAI
errSean Miletic; Simoun Icho; Zhijie Li; John Tam; Elizabeth C. Rose; Cypress E. Perkins; Ali Nakhi; Xinglin Yang; Howard C. Hang; John L. Rubinstein; Peter I. Dosa; Casey M. Theriot; Roman A. Melnyk
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Design, Synthesis, and Biological Evaluation of Mono- and Diamino-Substituted Squaramide Derivatives as Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthase
err2025-11-01
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PREAI
errPalme, Paul R.; Grover, Shipra; Abdelaziz, Rana; Mann, Lea; Kany, Andreas M.; Ouologuem, Lina; Bartel, Karin; Sonnenkalb, Lindsay; Reiling, Norbert; Hirsch, Anna K. H.; Schnappinger, Dirk; Rubinstein, John L.; Imming, Peter; Richter, Adrian
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Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity
errImmunity
IF26.3
err2025-10-09
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errOAAI
errEzra T. Bekkering; Randy Yoo; Sophia Hailemariam; Fabian Heide; Danton Ivanochko; Matthew Jackman; Nicholas I. Proellochs; Rianne Stoter; Geert-Jan van Gemert; Ayana Maeda; Takaaki Yuguchi; Oscar T. Wanders; Renate C. van Daalen; Maartje R. Inklaar; Carolina M. Andrade; Pascal W.T.C. Jansen; Michiel Vermeulen; Teun Bousema; Eizo Takashima; John L. Rubinstein; Taco W.A. Kooij; Matthijs M. Jore; Jean-Philippe Julien
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Structural elucidation of full-length Pfs48/45 in complex with potent monoclonal antibodies isolated from a naturally exposed individual
err2025-05-22
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errOAAI
errKucharska, Iga; Ivanochko, Danton; Hailemariam, Sophia; Inklaar, Maartje R.; Kim, Hee Ryung; Teelen, Karina; Stoter, Rianne; van de Vegte-bolmer, Marga; van Gemert, Geert-Jan; Semesi, Anthony; Mcleod, Brandon; Ki, Ahyoung; Lee, Won-Kyu; Rubinstein, John L.; Jore, Matthijs M.
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Conformational changes in the motor ATPase CpaF facilitate a rotary mechanism of Tad pilus assembly
err2025-04-24
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errOAAI
errYen, Ian Y.; Whitfield, Gregory B.; Rubinstein, John L.; Brun, Yves V.
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Structure of Mycobacterial NDH-2 Bound to a 2-Mercapto-Quinazolinone Inhibitor
err2025-03-21
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errOAAI
errLiang, Yingke; Bueler, Stephanie A.; Cook, Gregory M.; Rubinstein, John L.
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Structure of yeast RAVE bound to a partial V1 complex
err2024-12-03
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errOAAI
errWang, Hanlin; Tarsio, Maureen; Kane, Patricia M.; Rubinstein, John L.
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Structure of a dimeric full-length ABC transporter
err2024-11-16
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errOAAI
errBickers, Sarah C.; Benlekbir, Samir; Rubinstein, John L.; Kanelis, Voula
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Electron transfer in the respiratory chain at low salinity
err2024-09-19
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errOAAI
errLobez, Ana Paula; Wu, Fei; Di Trani, Justin M.; Rubinstein, John L.; Oliveberg, Mikael; Brzezinski, Peter; Moe, Agnes
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The V-ATPase/ATG16L1 axis is controlled by the V1H subunit
err2024-08-01
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errOAAI
errTimimi, Lewis; Wrobel, Antoni G.; Chiduza, George N.; Maslen, Sarah L.; Torres-Mendez, Antonio; Montaner, Beatriz; Davis, Colin; Minckley, Taylor; Hole, Katriona L.; Serio, Andrea; Devine, Michael J.; Skehel, J. Mark; Rubinstein, John L.; Schreiber, Anne; Beale, Rupert
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Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex
err2024-04-16
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errOAAI
errNguyen, Duc Minh; Rath, Deanna H.; Devost, Dominic; Petrin, Darlaine; Rizk, Robert; Ji, Alan X.; Narayanan, Naveen; Yong, Darren; Zhai, Andrew; Kuntz, Douglas A.; Mian, Maha U. Q.; Pomroy, Neil C.; Keszei, Alexander F. A.; Benlekbir, Samir; Mazhab-Jafari, Mohammad T.; Rubinstein, John L.; Hebert, Terence E.; Prive, Gilbert G.
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Poly(ADP-ribosyl)ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates
err2024-02-01
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PREAI
errNosella, Michael L.; Kim, Tae Hun; Huang, Shuya Kate; Harkness, Robert W.; Goncalves, Monica; Pan, Alisia; Tereshchenko, Maria; Vahidi, Siavash; Rubinstein, John L.; Lee, Hyun O.; Forman-Kay, Julie D.; Kay, Lewis E.
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A simple assay for inhibitors of mycobacterial oxidative phosphorylation
err2024-01-01
err5
errOAAI
errHarden, Serena A.; Courbon, Gautier M.; Liang, Yingke; Kim, Angelina S.; Rubinstein, John L.
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Structure of the bc1-cbb3 respiratory supercomplex from Pseudomonas aeruginosa
err2023-09-26
err5
errOAAI
errDi Trani, Justin M.; Gheorghita, Andreea A.; Turner, Madison; Brzezinski, Peter; Aedelroth, Pia; Vahidi, Siavash; Howell, P. Lynne; Rubinstein, John L.
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Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines
err2023-06-28
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errOAAI
errCourbon, Gautier M.; Palme, Paul R.; Mann, Lea; Richter, Adrian; Imming, Peter; Rubinstein, John L.
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The Sec1-Munc18 protein VPS33B forms a uniquely bidirectional complex with VPS16B
err2023-06-01
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errOAAI
errLiu, Richard J. Y.; Al-Molieh, Yusef; Chen, Shao Z.; Drobac, Marko; Urban, Denisa; Chen, Chang H.; Yao, Helen H. Y.; Geng, Ryan S. Q.; Li, Ling; Pluthero, Fred G.; Benlekbir, Samir; Rubinstein, John L.; Kahr, Walter H. A.
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A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo
err2023-05-24
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errOAAI
errAschner, Clare Burn; Muthuraman, Krithika; Kucharska, Iga; Cui, Hong; Prieto, Katherine; Nair, Manoj S.; Wang, Maple; Huang, Yaoxing; Christie-Holmes, Natasha; Poon, Betty; Lam, Jessica; Sultana, Azmiri; Kozak, Robert; Mubareka, Samira; Rubinstein, John L.; Rujas, Edurne; Treanor, Bebhinn; Ho, David D.; Jetha, Arif; Julien, Jean -Philippe
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