Not logged in Bnip3lb-driven mitophagy maintains fate of the embryonic hematopoietic stem cell pool Meader, Eleanor; Walcheck, Morgan T.; Leder, Mindy R.; Delaney, Patrice; Falchetti, Marcelo; Jing, Ran; Li, Christopher; Kambli, Netra K.; Wrighton, Paul J.; Sugden, Wade W.; Najia, Mohamad A.; Oderberg, Isaac M.; Taylor, Vivian M.; Leblanc, Zachary C.; Quenzer, Eleanor D.; Lim, Sung-Eun; Schlaeger, Thorsten; Daley, George Q.; Goessling, Wolfram; North, Trista E. Share Save
A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs Conway, Ashlee J.; Rosanwo, Tolulope O.; Williamson, Thomas E.; Landry, Samuel; Kinney, Melissa A.; Clark, Martha A.; Vo, Linda T.; Rowe, R. Grant; Marion, William; Zhang, Yosra; Mullin, Nathaniel K.; Shi, Michael; Archer, Natasha M.; Heeney, Matthew M.; Schlaeger, Thorsten M.; Bauer, Daniel E.; Duraisingh, Manoj T.; Brugnara, Carlo; North, Trista E.; Daley, George Q. Share Save
EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity (vol 29, pg 1181, 2022) Jing, Ran; Scarfo, Irene; Najia, Mohamad Ali; da Rocha, Edroaldo Lummertz; Han, Areum; Sanborn, Michael; Bingham, Trevor; Kubaczka, Caroline; Jha, Deepak K.; Falchetti, Marcelo; Schlaeger, Thorsten M.; North, Trista E.; V. Maus, Marcela; Daley, George Q. Share Save
Maturation and persistence of CAR T cells derived from human pluripotent stem cells via chemical inhibition of G9a/GLP (vol 32, pg 71, 2025) Jing, Ran; Falchetti, Marcelo; Han, Tianxiao; Najia, Mohamad; Hensch, Luca T.; Meader, Eleanor; da Rocha, Edroaldo Lummertz; Kononov, Martin; Wang, Stephanie; Bingham, Trevor; Li, Zhiheng; Zhao, Yunliang; Frenis, Katie; Kubaczka, Caroline; Yang, Song; Jha, Deepak; Rodrigues-Luiz, Gabriela F.; Rowe, R. Grant; Schlaeger, Thorsten M.; V. Maus, Marcela; North, Trista E.; Zon, Leonard I.; Daley, George Q. Share Save
A conserved transcription factor regulatory program promotes tendon fate Niu, Xubo; Melendez, Delmy L.; Raj, Suyash; Cai, Junming; Senadeera, Dulanjalee; Mandelbaum, Joseph; Shestopalov, Ilya A.; Martin, Scott D.; Zon, Leonard I.; Schlaeger, Thorsten M.; Lai, Lick Pui; McMahon, Andrew P.; Craft, April M.; Galloway, Jenna L. Share Save
Transcription Factor Programming of Human iPSC-Derived Sinusoidal Vascular Endothelial Cells Enhances Co-Cultured Hematopoietic Stem and Progenitor Cell Transplantation Han, Tianxiao; Gunage, Rajesh D.; Jing, Ran; Stockard, Olivia; Corbin, Alexandra F.; Hensch, Luca; Tang, Yang; Chen, Kenny; Yang, Song; Zhou, Yi; Daley, George Q.; Schlaeger, Thorsten M.; Zon, Leonard I. Share Save
Matrin3 mediates differentiation through stabilizing chromatin loop-domain interactions and YY1 mediated enhancer-promoter interactions Liu, Tianxin; Zhu, Qian; Kai, Yan; Bingham, Trevor; Wang, Stacy; Cha, Hye Ji; Mehta, Stuti; Schlaeger, Thorsten M.; Yuan, Guo-Cheng; Orkin, Stuart H. Share Save
Share Save
Synthetic genetic circuits to uncover the OCT4 trajectories of successful reprogramming of human fibroblasts Ilia, Katherine; Shakiba, Nika; Bingham, Trevor; Jones, Ross D.; Kaminski, Michael M.; Aravera, Eliezer; Bruno, Simone; Palacios, Sebastian; Weiss, Ron; Collins, James J.; Del Vecchio, Domitilla; Schlaeger, Thorsten M. Share Save
RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia Marion, William; Koppe, Tiago; Chen, Chun-Chin; Wang, Dahai; Frenis, Katie; Fierstein, Sara; Sensharma, Prerana; Aumais, Olivia; Peters, Michael; Ruiz-Torres, Sonya; Chihanga, Tafadzwa; Boettcher, Steffen; Shimamura, Akiko; Bauer, Daniel E.; Schlaeger, Thorsten; Wells, Susanne I. I.; Ebert, Benjamin L. L.; Starczynowski, Daniel; da Rocha, Edroaldo Lummertz; Rowe, R. Grant Share Save
De Novo Generation of Pulmonary Ionocytes from Normal and Cystic Fibrosis Human Induced Pluripotent Stem Cells Wang, Ruobing; Simone-Roach, Chantelle; Lindstrom-Vautrin, Jonathan; Wang, Feiya; Rollins, Stuart; Bawa, Pushpinder Singh; Lu, Junjie; Tang, Yang; Beermann, Mary Lou; Schlaeger, Thorsten; Mahoney, John; Rowe, Steven M.; Hawkins, Finn J.; Kotton, Darrell N. Share Save
Share Save
Extracellular vesicles improve GABAergic transmission in Huntington's disease iPSC-derived neurons Beatriz, Margarida; Rodrigues, Ricardo J.; Vilaca, Rita; Egas, Conceicao; Pinheiro, Paulo S.; Daley, George Q.; Schlaeger, Thorsten M.; Raimundo, Nuno; Rego, A. Cristina; Lopes, Carla Share Save
EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity Jing, Ran; Scarfo, Irene; Najia, Mohamad Ali; da Rocha, Edroaldo Lummertz; Han, Areum; Sanborn, Michael; Bingham, Trevor; Kubaczka, Caroline; Jha, Deepak K.; Falchetti, Marcelo; Schlaeger, Thorsten M.; North, Trista E.; Maus, Marcela, V; Daley, George Q. Share Save
Congenital X-linked neutropenia with myelodysplasia and somatic tetraploidy due to a germline mutation in SEPT6 Renella, Raffaele; Gagne, Katelyn; Beauchamp, Ellen; Fogel, Jonathan; Perlov, Aleksej; Sola, Mireia; Schlaeger, Thorsten; Hofmann, Inga; Shimamura, Akiko; Ebert, Benjamin L.; Schmitz-Abe, Klaus; Markianos, Kyriacos; Murphy, Kristi; Sun, Liang; Rockowitz, Shira; Sliz, Piotr; Campagna, Dean R.; Springer, Timothy A.; Bahl, Christopher; Agarwal, Suneet; Fleming, Mark D.; Williams, David A. Share Save
Genome sequencing unveils a regulatory landscape of platelet reactivity Keramati, Ali R.; Chen, Ming-Huei; Rodriguez, Benjamin A. T.; Yanek, Lisa R.; Bhan, Arunoday; Gaynor, Brady J.; Ryan, Kathleen; Brody, Jennifer A.; Zhong, Xue; Wei, Qiang; Kammers, Kai; Kanchan, Kanika; Iyer, Kruthika; Kowalski, Madeline H.; Pitsillides, Achilleas N.; Cupples, L. Adrienne; Li, Bingshan; Schlaeger, Thorsten M.; Shuldiner, Alan R.; O'Connell, Jeffrey R.; Ruczinski, Ingo; Mitchell, Braxton D.; Faraday, Nauder; Taub, Margaret A.; Becker, Lewis C.; Lewis, Joshua P.; Mathias, Rasika A.; Johnson, Andrew D. Share Save
A recurrent, homozygous EMC10 frameshift variant is associated with a syndrome of developmental delay with variable seizures and dysmorphic features Shao, Diane D.; Straussberg, Rachel; Ahmed, Hind; Khan, Amjad; Tian, Songhai; Hill, R. Sean; Smith, Richard S.; Majmundar, Amar J.; Ameziane, Najim; Neil, Jennifer E.; Yang, Edward; Al Tenaiji, Amal; Jamuar, Saumya S.; Schlaeger, Thorsten M.; Al-Saffar, Muna; Hovel, Iris; Al-Shamsi, Aisha; Basel-Salmon, Lina; Amir, Achiya Z.; Rento, Lariza M.; Lim, Jiin Ying; Ganesan, Indra; Shril, Shirlee; Evrony, Gilad; Barkovich, A. James; Bauer, Peter; Hildebrandt, Friedhelm; Dong, Min; Borck, Guntram; Beetz, Christian; Al-Gazali, Lihadh; Eyaid, Wafaa; Walsh, Christopher A. Share Save
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells Hawkins, Finn J.; Suzuki, Shingo; Beermann, Mary Lou; Barilla, Cristina; Wang, Ruobing; Villacorta-Martin, Carlos; Berical, Andrew; Jean, J. C.; Le Suer, Jake; Matte, Taylor; Simone-Roach, Chantelle; Tang, Yang; Schlaeger, Thorsten M.; Crane, Ana M.; Matthias, Nadine; Huang, Sarah X. L.; Randell, Scott H.; Wu, Joshua; Spence, Jason R.; Carraro, Gianni; Stripp, Barry R.; Rab, Andras; Sorsher, Eric J.; Horani, Amjad; Brody, Steven L.; Davis, Brian R.; Kotton, Darrell N. Share Save
An induced pluripotent stem cell model of Fanconi anemia reveals mechanisms of p53-driven progenitor cell differentiation Marion, William; Boettcher, Steffen; Ruiz-Torres, Sonya; da Rocha, Edroaldo Lummertz; Lundin, Vanessa; Morris, Vivian; Chou, Stephanie; Zhao, Anna M.; Kubaczka, Caroline; Aumais, Olivia; Zhang, Yosra; Shimamura, Akiko; Schlaeger, Thorsten M.; North, Trista E.; Ebert, Benjamin L.; Wells, Susanne, I; Daley, George Q.; Rowe, R. Grant Share Save
.png){kind=icon}
.png){kind=icon}
Not logged in.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
