Not logged in.png)
Share.png)
SaveShare Save Altered expression of Presenilin2 impacts endolysosomal homeostasis and synapse function in Alzheimer's disease-relevant brain circuits
Perdok, Anika; Van Acker, Zoe P.; Vrancx, Celine; Sannerud, Ragna; Vorsters, Inge; Verrengia, Assunta; Callaerts-Vegh, Zsuzsanna; Creemers, Eline; Fernandez, Sara Gutierrez; D'hauw, Britt; Serneels, Lutgarde; Wierda, Keimpe; Chavez-Gutierrez, Lucia; Annaert, Wim Share Save APOE from astrocytes restores Alzheimer's Aβ-pathology and DAM-like responses in APOE deficient microgliaPreman, Pranav; Moechars, Daan; Fertan, Emre; Wolfs, Leen; Serneels, Lutgarde; Shah, Disha; Lamote, Jochen; Poovathingal, Suresh; Snellinx, An; Mancuso, Renzo; Balusu, Sriram; Klenerman, David; Arranz, Amaia M.; Fiers, Mark; De Strooper, Bart Share Save Associations of amyloid-β oligomers and plaques with neuropathology in the AppNL-G-F mouseTang, Jiabin; Huang, Helen; Muirhead, Robert C. J.; Zhou, Yue; Li, Junheng; DeFelice, John; Kopanitsa, Maksym, V; Serneels, Lutgarde; Davey, Karen; Tilley, Bension S.; Gentleman, Steve; Matthews, Paul M. Share Save Share Save The y-secretase substrate proteome and its role in cell signaling regulationHou, Pengfei; Zielonka, Magdalena; Serneels, Lutgarde; Martinez-Muriana, Anna; Fattorelli, Nicola; Wolfs, Leen; Poovathingal, Suresh; T'Syen, Dries; Balusu, Sriram; Theys, Tom; Fiers, Mark; Mancuso, Renzo; Howden, Andrew J. M.; De Strooper, Bart; Theys, Tom; Fiers, Mark; Mancuso, Renzo Share Save Share Save Selective inhibitors of the PSEN1-gamma-secretase complexSerneels, Lutgarde; Narlawar, Rajeshwar; Perez-Benito, Laura; Municoy, Marti; Guallar, Victor; T'Syen, Dries; Dewilde, Maarten; Bischoff, Francois; Fraiponts, Erwin; Tresadern, Gary; Roevens, Peter W. M.; Gijsen, Harrie J. M.; De Strooper, Bart Share Save Share Save Hyperspectral retinal imaging in mouse models of proteinopathies identifies disease-specific signaturesDe Groef, Lies; Veys, Lien; Hadoux, Xavier; Vandenabeele, Marjan; Lemmens, Sophie; Serneels, Lutgarde; Theunis, Jan; De Strooper, Bart; Stalmans, Ingeborg; van Wijngaarden, Peter; Moons, Lieve Share Save The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and researchVandenabeele, Marjan; Veys, Lien; Lemmens, Sophie; Hadoux, Xavier; Gelders, Geraldine; Masin, Luca; Serneels, Lutgarde; Theunis, Jan; Saito, Takashi; Saido, Takaomi C.; Jayapala, Murali; De Boever, Patrick; De Strooper, Bart; Stalmans, Ingeborg; van Wijngaarden, Peter; Moons, Lieve; De Groef, Lies Share Save Share Save Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D-and Elastically Reconstructed 3D-MALDI MS ImagesEnzlein, Thomas; Cordes, Jonas; Munteanu, Bogdan; Michno, Wojciech; Serneels, Lutgarde; De Strooper, Bart; Hanrieder, Jorg; Wolf, Ivo; Chavez-Gutierrez, Lucia; Hopf, Carsten Share Save Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibitionHabets, Roger A.; de Bock, Charles E.; Serneels, Lutgarde; Lodewijckx, Inge; Verbeke, Delphine; Nittner, David; Narlawar, Rajeshwar; Demeyer, Sofie; Dooley, James; Liston, Adrian; Taghon, Tom; Cools, Jan; de Strooper, Bart Share Save PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndromeSpinazzi, Marco; Radaelli, Enrico; Horre, Katrien; Arranz, Amaia M.; Gounko, Natalia V.; Agostinis, Patrizia; Maia, Teresa Mendes; Impens, Francis; Morais, Vanessa Alexandra; Lopez-Lluch, Guillermo; Serneels, Lutgarde; Navas, Placido; De Strooper, Bart Share Save Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegenerationGarcia-Leon, Juan Antonio; Cabrera-Socorro, Alfredo; Eggermont, Kristel; Swijsen, Ann; Terryn, Joke; Fazal, Raheem; Nami, FatemehArefeh; Ordovas, Laura; Quiles, Ana; Lluis, Frederic; Serneels, Lutgarde; Wierda, Keimpe; Sierksma, Annerieke; Kreir, Mohamed; Pestana, Francisco; Van Damme, Philip; De Strooper, Bart; Thorrez, Lieven; Ebneth, Andreas; Verfaillie, Catherine M. Share Save Share Save Share Save The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and ObesityDooley, James; Garcia-Perez, Josselyn E.; Sreenivasan, Jayasree; Schlenner, Susan M.; Vangoitsenhoven, Roman; Papadopoulou, Aikaterini S.; Tian, Lei; Schonefeldt, Susann; Serneels, Lutgarde; Deroose, Christophe; Staats, Kim A.; Van der Schueren, Bart; De Strooper, Bart; McGuinness, Owen P.; Mathieu, Chantal; Liston, Adrian Share Save 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
