Not logged in Engineering neuronal networks in granular microgels to innervate bioprinted cancer organoids on-a-chip Fredrikson, Jacob P.; Roth, Daniela M.; Cosgrove, Jameson A.; Sener, Gulsu; Crow, Lily A.; Eckenstein, Kazumi; Wu, Lillian; Hosseini, Mahshid; Thomas, George; Eksi, Sebnem Ece Share Save
Share Save
Share Save
S6K1-/-/S6K2-/- mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway Pende, M; Um, SH; Mieulet, V; Sticker, M; Goss, VL; Mestan, J; Mueller, M; Fumagalli, S; Kozma, SC; Thomas, G Share Save
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development Gangloff, YG; Mueller, M; Dann, SG; Svoboda, P; Sticker, M; Spetz, JF; Um, SH; Brown, EJ; Cereghini, S; Thomas, G; Kozma, SC Share Save
Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy McMullen, JR; Shioi, T; Zhang, L; Tarnavski, O; Sherwood, MC; Dorfman, AL; Longnus, S; Pende, M; Martin, KA; Blenis, J; Thomas, G; Izumo, S Share Save
Share Save
Share Save
A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis Lluch, Aina; Veiga, Sonia R.; Latorre, Jessica; Moreno-Navarrete, Jose M.; Bonifaci, Nuria; Nguyen, Van Dien; Zhou, You; Hoering, Marcus; Liebisch, Gerhard; Olkkonen, Vesa M.; Llobet-Navas, David; Thomas, George; Rodriguez-Barrueco, Ruth; Fernandez-Real, Jose M.; Kozma, Sara C.; Ortega, Francisco J. Share Save
Share Save
A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies Wise-Draper, Trisha M.; Moorthy, Ganesh; Salkeni, Mohamad A.; Karim, Nagla Abdel; Thomas, Hala Elnakat; Mercer, Carol A.; Beg, M. Shalaan; O'Gara, Sue; Olowokure, Olugbenga; Fathallah, Hassana; Kozma, Sara C.; Thomas, George; Rixe, Olivier; Desai, Pankaj; Morris, John C. Share Save
S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis Yi, Sang Ah; Um, Sung Hee; Lee, Jaecheol; Yoo, Ji Hee; Bang, So Young; Park, Eun Kyung; Lee, Min Gyu; Nam, Ki Hong; Jeon, Ye Ji; Park, Jong Woo; You, Jueng Soo; Lee, Sang-Jin; Bae, Gyu-Un; Rhie, Jong Won; Kozma, Sara C.; Thomas, George; Han, Jeung-Whan Share Save
S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3 Wang, Fuan; Alain, Tommy; Szretter, Kristy J.; Stephenson, Kyle; Pol, Jonathan G.; Atherton, Matthew J.; Hoang, Huy-Dung; Fonseca, Bruno D.; Zakaria, Chadi; Chen, Lan; Rangwala, Zainab; Hesch, Adam; Chan, Eva Sin Yan; Tuinman, Carly; Suthar, Mehul S.; Jiang, Zhaozhao; Ashkar, Ali A.; Thomas, George; Kozma, Sara C.; Gale, Michael, Jr.; Fitzgerald, Katherine A.; Diamond, Michael S.; Mossman, Karen; Sonenberg, Nahum; Wan, Yonghong; Lichty, Brian D. Share Save
Share Save
Share Save
Share Save
S6K1 controls pancreatic β cell size independently of intrauterine growth restriction Um, Sung Hee; Sticker-Jantscheff, Melanie; Chau, Gia Cac; Vintersten, Kristina; Mueller, Matthias; Gangloff, Yann-Gael; Adams, Ralf H.; Spetz, Jean-Francois; Elghazi, Lynda; Pfluger, Paul T.; Pende, Mario; Bernal-Mizrachi, Ernesto; Tauler, Albert; Tschoep, Matthias H.; Thomas, George; Kozma, Sara C. Share Save
Share Save
A Synthetic Lethal Screen Reveals Enhanced Sensitivity to ATR Inhibitor Treatment in Mantle Cell Lymphoma with ATM Loss-of-Function Menezes, Daniel L.; Holt, Jenny; Tang, Yan; Feng, Jiajia; Barsanti, Paul; Pan, Yue; Ghoddusi, Majid; Zhang, Wei; Thomas, George; Holash, Jocelyn; Lees, Emma; Taricani, Lorena Share Save
Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors Barsanti, Paul A.; Aversa, Robert J.; Jin, Xianming; Pan, Yue; Lu, Yipin; Elling, Robert; Jain, Rama; Knapp, Mark; Lan, Jiong; Lin, Xiaodong; Rudewicz, Patrick; Sim, Janet; Taricani, Lorena; Thomas, George; Xiao, Linda; Yue, Qin Share Save
.png){kind=icon}
.png){kind=icon}
Not logged in.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
