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ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis Yang, Yongbing; Wang, Yanan; Wang, Zhongcheng; Yan, Huanyu; Gong, Yi; Hu, Yingchao; Jiang, Yuying; Wen, Shuang; Xu, Feifei; Wang, Bingwei; Humphries, Fiachra; Chen, Yun; Wang, Xi; Yang, Shuo Share Save
Cellular nucleic acid- binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA-protein condensates Chen, Yongzhi; Lei, Xuqiu; Jiang, Zhaozhao; Humphries, Fiachra; Parsi, Krishna Mohan; Mustone, Nicholas J.; Ramos, Irene; Mutetwa, Tinaye; Sesma, Ana Fernandez-; Maehr, Rene; Caffrey, Daniel R.; Fitzgerald, Katherine A. Share Save
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Development of LB244, an Irreversible STING Antagonist Barasa, Leonard; Chaudhuri, Sauradip; Zhou, Jeffrey Y.; Jiang, Zhaozhao; Choudhary, Shruti; Green, Robert Madison; Wiggin, Elenore; Cameron, Michael; Humphries, Fiachra; Fitzgerald, Katherine A.; Thompson, Paul R. Share Save
Targeting STING oligomerization with small- molecule inhibitors Humphries, Fiachra; Shmuel-Galia, Liraz; Jiang, Zhaozhao; Zhou, Jeffrey Y.; Barasa, Leonard; Mondal, Santanu; Wilson, Ruth; Sultana, Nadia; Shaffer, Scott A.; Ng, Sze -Ling; Pesiridis, G. Scott; Thompson, Paul R.; Fitzgerald, Katherine A. Share Save
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Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection Hariharan, Vignesh N.; Shin, Minwook; Chang, Ching-Wen; O'Reilly, Daniel; Biscans, Annabelle; Yamada, Ken; Guo, Zhiru; Somasundaran, Mohan; Tang, Qi; Monopoli, Kathryn; Krishnamurthy, Pranathi Meda; Devi, Gitali; McHugh, Nicholas; Cooper, David A.; Echeverria, Dimas; Cruz, John; Chan, Io Long; Liu, Ping; Lim, Sun-Young; McConnell, Jill; Singh, Satya Prakash; Hildebrand, Samuel; Sousa, Jacquelyn; Davis, Sarah M.; Kennedy, Zachary; Ferguson, Chantal; Godinho, Bruno M. D. C.; Thillier, Yann; Caiazzi, Jillian; Ly, Socheata; Muhuri, Manish; Kelly, Karen; Humphries, Fiachra; Cousineau, Alyssa; Parsi, Krishna Mohan; Li, Qi; Wang, Yang; Maehr, Rene; Gao, Guangping; Korkin, Dmitry; McDougall, William M.; Finberg, Robert W.; Fitzgerald, Katherine A.; Wang, Jennifer P.; Watts, Jonathan K.; Khvorova, Anastasia Share Save
Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade Jiang, Yuying; Yang, Yongbing; Hu, Yingchao; Yang, Rui; Huang, Jiajia; Liu, Yi; Wu, Yuqing; Li, Sheng; Ma, Chunmei; Humphries, Fiachra; Wang, Bingwei; Wang, Xi; Hu, Zhibin; Yang, Shuo Share Save
Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants Li, Qi; Humphries, Fiachra; Girardin, Roxie C.; Wallace, Aaron; Ejemel, Monir; Amcheslavsky, Alla; McMahon, Conor T.; Schiller, Zachary A.; Ma, Zepei; Cruz, John; Dupuis, Alan P.; Payne, Anne F.; Maryam, Arooma; Yilmaz, Nese Kurt; McDonough, Kathleen A.; Pierce, Brian G.; Schiffer, Celia A.; Kruse, Andrew C.; Klempner, Mark S.; Cavacini, Lisa A.; Fitzgerald, Katherine A.; Wang, Yang Share Save
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ECSIT is a critical limiting factor for cardiac function Xu, Linan; Humphries, Fiachra; Delagic, Nezira; Wang, Bingwei; Holland, Ashling; Edgar, Kevin S.; Hombrebueno, Jose R.; Stolz, Donna Beer; Oleszycka, Ewa; Rodgers, Aoife M.; Glezeva, Nadezhda; McDonald, Kenneth; Watson, Chris J.; Ledwidge, Mark T.; Ingram, Rebecca J.; Grieve, David J.; Moynagh, Paul N. Share Save
Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells Shmuel-Galia, Liraz; Humphries, Fiachra; Lei, Xuqiu; Ceglia, Simona; Wilson, Ruth; Jiang, Zhaozhao; Ketelut-Carneiro, Natalia; Foley, Sage E.; Pechhold, Susanne; Houghton, JeanMarie; Muneeruddin, Khaja; Shaffer, Scott A.; McCormick, Beth A.; Reboldi, Andrea; Ward, Doyle; Marshak-Rothstein, Ann; Fitzgerald, Katherine A. Share Save
A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection Humphries, Fiachra; Shmuel-Galia, Liraz; Jiang, Zhaozhao; Wilson, Ruth; Landis, Philip; Ng, Sze-Ling; Parsi, Krishna-Mohan; Maehr, Rene; Cruz, John; Morales-Ramos, Angel; Ramanjulu, Joshi M.; Bertin, John; Pesiridis, G. Scott; Fitzgerald, Katherine A. Share Save
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression Balic, Jesse J.; Albargy, Hassan; Luu, Kevin; Kirby, Francis J.; Jayasekara, W. Samantha N.; Mansell, Finbar; Garama, Daniel J.; De Nardo, Dominic; Baschuk, Nikola; Louis, Cynthia; Humphries, Fiachra; Fitzgerald, Katherine; Latz, Eicke; Gough, Daniel J.; Mansell, Ashley Share Save
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