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An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes Zhang, Yuanjin; Liu, Zhonglin; Hirschi, Marscha; Brodsky, Oleg; Johnson, Eric; Won, Sang Joon; Nagata, Asako; Bezwada, Divya; Petroski, Matthew D.; Majmudar, Jaimeen D.; Niessen, Sherry; Vanarsdale, Todd; Gilbert, Adam M.; Hayward, Matthew M.; Stewart, Al E.; Nager, Andrew R.; Melillo, Bruno; Cravatt, Benjamin F. Share Save
Electron transport chain inhibition increases cellular dependence on purine transport and salvage Wu, Zheng; Bezwada, Divya; Cai, Feng; Harris, Robert C.; Ko, Bookyung; Sondhi, Varun; Pan, Chunxiao; Vu, Hieu S.; Nguyen, Phong T.; Faubert, Brandon; Cai, Ling; Chen, Hongli; Martin-Sandoval, Misty; Do, Duyen; Gu, Wen; Zhang, Yuanyuan; Zhang, Yuannyu; Brooks, Bailey; Kelekar, Sherwin; Zacharias, Lauren G.; Oaxaca, K. Celeste; Patricio, Joao S.; Mathews, Thomas P.; Garcia-Bermudez, Javier; Ni, Min; DeBerardinis, Ralph J. Share Save
Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples Cai, Feng; Bezwada, Divya; Cai, Ling; Mahar, Rohit; Wu, Zheng; Chang, Mario C.; Pachnis, Panayotis; Yang, Chendong; Kelekar, Sherwin; Gu, Wen; Brooks, Bailey; Ko, Bookyung; Vu, Hieu S.; Mathews, Thomas P.; Zacharias, Lauren G.; Martin-Sandoval, Misty; Do, Duyen; Oaxaca, K. Celeste; Jin, Eunsook S.; Margulis, Vitaly; Malloy, Craig R.; Merritt, Matthew E.; Deberardinis, Ralph J. Share Save
Adipocytes reprogram cancer cell metabolism by diverting glucose towards glycerol-3-phosphate thereby promoting metastasis Mukherjee, Abir; Bezwada, Divya; Greco, Francesco; Zandbergen, Malu; Shen, Tong; Chiang, Chun-Yi; Tasdemir, Medine; Fahrmann, Johannes; Grapov, Dmitry; La Frano, Michael R.; Vu, Hieu S.; Faubert, Brandon; Newman, John W.; Mcdonnell, Liam A.; Nezi, Luigi; Fiehn, Oliver; Deberardinis, Ralph J.; Lengyel, Ernst Share Save
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Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells Aurora, Arin B.; Khivansara, Vishal; Leach, Ashley; Gill, Jennifer G.; Martin-Sandoval, Misty; Yang, Chendong; Kasitinon, Stacy Y.; Bezwada, Divya; Tasdogan, Alpaslan; Gu, Wen; Mathews, Thomas P.; Zhao, Zhiyu; DeBerardinis, Ralph J.; Morrison, Sean J. Share Save
Fatty acid synthesis is required for breast cancer brain metastasis (vol 2, pg 414, 2021) Ferraro, Gino B.; Ali, Ahmed; Luengo, Alba; Kodack, David P.; Deik, Amy; Abbott, Keene L.; Bezwada, Divya; Blanc, Landry; Prideaux, Brendan; Jin, Xin; Posada, Jessica M.; Chen, Jiang; Chin, Christopher R.; Amoozgar, Zohreh; Ferreira, Raphael; Chen, Ivy X.; Naxerova, Kamila; Ng, Christopher; Westermark, Anna M.; Duquette, Mark; Roberge, Sylvie; Lindeman, Neal I.; Lyssiotis, Costas A.; Nielsen, Jens; Housman, David E.; Duda, Dan G.; Brachtel, Elena; Golub, Todd R.; Cantley, Lewis C.; Asara, John M.; Davidson, Shawn M.; Fukumura, Dai; Dartois, Veronique A.; Clish, Clary B.; Jain, Rakesh K.; Vander Heiden, Matthew G. Share Save
Mitochondrial NADP+ is essential for proline biosynthesis during cell growth Tran, Diem H.; Kesavan, Rushendhiran; Rion, Halie; Soflaee, Mona Hoseini; Solmonson, Ashley; Bezwada, Divya; Vu, Hieu S.; Cai, Feng; Phillips, John A., III; DeBerardinis, Ralph J.; Hoxhaj, Gerta Share Save
Fatty acid synthesis is required for breast cancer brain metastasis Ferraro, Gino B.; Ali, Ahmed; Luengo, Alba; Kodack, David P.; Deik, Amy; Abbott, Keene L.; Bezwada, Divya; Blanc, Landry; Prideaux, Brendan; Jin, Xin; Possada, Jessica M.; Chen, Jiang; Chin, Christopher R.; Amoozgar, Zohreh; Ferreira, Raphael; Chen, Ivy X.; Naxerova, Kamila; Ng, Christopher; Westermark, Anna M.; Duquette, Mark; Roberge, Sylvie; Lindeman, Neal I.; Lyssiotis, Costas A.; Nielsen, Jens; Housman, David E.; Duda, Dan G.; Brachtel, Elena; Golub, Todd R.; Cantley, Lewis C.; Asara, John M.; Davidson, Shawn M.; Fukumura, Dai; Dartois, Veronique A.; Clish, Clary B.; Jain, Rakesh K.; Vander Heiden, Matthew G. Share Save
TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling Kasitinon, Stacy Y.; Eskiocak, Ugur; Martin, Misty; Bezwada, Divya; Khivansara, Vishal; Tasdogan, Alpaslan; Zhao, Zhiyu; Mathews, Thomas; Aurora, Arin B.; Morrison, Sean J. Share Save
Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo Courtney, Kevin D.; Bezwada, Divya; Mashimo, Tomoyuki; Pichumani, Kumar; Vemireddy, Vamsidhara; Funk, Alexander M.; Wimberly, Jennifer; McNeil, Sarah S.; Kapur, Payal; Lotan, Yair; Margulis, Vitaly; Cadeddu, Jeffrey A.; Pedrosa, Ivan; DeBerardinis, Ralph J.; Malloy, Craig R.; Bachoo, Robert M.; Maher, Elizabeth A. Share Save
Hypoxia regulation of antigen presentation machinery expression in breast cancer Ng, Mei Rosa; Sabbatino, Francesco; Duquette, Mark; Naxerova, Kamila; Badeaux, Mark; Ferraro, Gino B.; Chin, Shan M.; Bezwada, Divya; Brachtel, Elena F.; Ferrone, Soldano; Jain, Rakesh K. Share Save
The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation Ferraro, Gino B.; Kodack, David P.; Askoxylakis, Vasileios; Sheng, Qing; Badeaux, Mark; Goel, Shom; Qi, Xiaolong; Shankaraiah, Ram; Cao, Alexander Z.; Ramjiawan, Rakesh R.; Bezwada, Divya; Patel, Bhushankumar; Song, Youngchul; Costa, Carlotta; Naxerova, Kamila; Wong, Christina; Kloepper, Jonas; Das, Rita; Tam, Angela; Tanboon, Jantima; Duda, Dan G.; Miller, Ryan C.; Siegel, Marni B.; Anders, Carey K.; Sanders, Melinda; Estrada, Valeria M.; Schlegel, Robert; Arteaga, Carlos L.; Brachtel, Elena; Huang, Alan; Fukumura, Dai; Engelman, Jeffrey A.; Jain, Rakesh K. Share Save
The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation Kodack, David P.; Askoxylakis, Vasileios; Ferraro, Gino B.; Sheng, Qing; Badeaux, Mark; Goel, Shom; Qi, Xiaolong; Shankaraiah, Ram; Cao, Z. Alexander; Ramjiawan, Rakesh R.; Bezwada, Divya; Patel, Bhushankumar; Song, Yongchul; Costa, Carlotta; Naxerova, Kamila; Wong, Christina S. F.; Kloepper, Jonas; Das, Rita; Tam, Angela; Tanboon, Jantima; Duda, Dan G.; Miller, C. Ryan; Siegel, Marni B.; Anders, Carey K.; Sanders, Melinda; Estrada, Monica V.; Schlegel, Robert; Arteaga, Carlos L.; Brachtel, Elena; Huang, Alan; Fukumura, Dai; Engelman, Jeffrey A.; Jain, Rakesh K. Share Save
Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment Askoxylakis, Vasileios; Ferraro, Gino B.; Kodack, David P.; Badeaux, Mark; Shankaraiah, Ram C.; Seano, Giorgio; Kloepper, Jonas; Vardam, Trupti; Martin, John D.; Naxerova, Kamila; Bezwada, Divya; Qi, Xiaolong; Selig, Martin K.; Brachtel, Elena; Duda, Dan G.; Huang, Peigen; Fukumura, Dai; Engelman, Jeffrey A.; Jain, Rakesh K. Share Save
PF-06463922, a novel next generation ALK/ROS1 inhibitor, overcomes resistance to 1st and 2nd generation ALK inhibitors in pre-clinical models Friboulet, Luc; Zou, Helen; Kodack, David P.; Engstrom, Lars D.; Li, Qiuhua; West, Melissa; Tang, Ruth W.; Wang, Hui; Tsaparikos, Konstantinos; Wang, Jinwei; Timofeevski, Sergei; Dinh, Dac M.; Hieu Lam; Lam, Justine L.; Yamazaki, Shinji; Hu, Wenyue; Patel, Bhushankumar; Bezwada, Divya; Mahmood, Sidra; Lifshits, Eugene; Affolter, Timothy; Lappin, Patrick B.; Gukasyan, Hovhannes; Lee, Nathan; Deng, Shibing; Jain, Rakesh K.; Johnson, Ted W.; Shaw, Alice T.; Fantin, Valeria R.; Smeal, Tod Share Save
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