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The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors Alexander, Stephen P. H.; Davenport, Anthony P.; Kelly, Eamonn; Gibb, Alasdair J.; Mathie, Alistair A.; Peach, Chloe J.; Veale, Emma L.; Armstrong, Jane F.; Faccenda, Elena; Harding, Simon D.; Southan, Christopher; Davies, Jamie A.; Abbracchio, Maria Pia; Abraham, George R.; Agoulnik, Alexander; Alexander, Wayne; Al-hosaini, Khaled; Back, Magnus; Baker, Jillian G.; Barnes, Nicholas M.; Bathgate, Ross; Beaulieu, Jean-Martin; Beck-Sickinger, Annette G.; Behrens, Maik; Bennett, Kirstie A.; Bernstein, Kenneth E.; Bettler, Bernhard; Birdsall, Nigel J. M.; Blaho, Victoria A.; Bonaventure, Pascal; Boulay, Francois; Bousquet, Corinne; Brauner-Osborne, Hans; Brown, Andrew J.; Burnstock, Geoffrey; Busnelli, Marta; Calo, Girolamo; Caruso, Vanni; Castano, Justo P.; Catt, Kevin J.; Ceruti, Stefania; Chazot, Paul; Chiang, Nan; Chini, Bice; Christopoulos, Arthur; Chun, Jerold; Cianciulli, Antonia; Civelli, Olivier; Clapp, Lucie H.; Couture, Rejean; Cox, Helen M.; Csaba, Zsolt; Dahlgren, Claes; Dautzenberg, Frank M.; Dent, Gordon; Douglas, Steven D.; Dournaud, Pascal; Dubocovich, Margarita L.; Eguchi, Satoru; Escher, Emanuel; Filardo, Edward J.; Fong, Tung; Forsman, Huamei Fu; Fumagalli, Marta; Gainetdinov, Raul R.; Garelja, Michael L.; de Gasparo, Marc; Gbahou, Florence; Gerard, Craig; Gershengorn, Marvin; Glass, Michelle; Gloriam, David E.; Gobeil, Fernand; Goodfriend, Theodore L.; Goudet, Cyril; Gratz, Lukas; Gregory, Karen J.; Gruber, Christian; Gundlach, Andrew L.; Hamann, Jorg; Hanson, Julien; Hartman, Deborah S.; Hauger, Richard L.; Hay, Debbie L.; Heinemann, Akos; Heitman, Laura; Herr, Deron R.; Hollenberg, Morley D.; Holliday, Nicholas D.; Holst, Birgitte; Horiuchi, Mastgugu; Hoyer, Daniel; Hunyady, Laszlo; Husain, Ahsan; IJzerman, Adriaan P.; Inagami, Tadashi; Insel, Paul A.; Jacobson, Kenneth A.; Jacobson, Laura H.; Jensen, Robert T.; Jockers, Ralf; Jonnalagadda, Deepa; Karnik, Sadashiva; Kaupmann, Klemens; Kemp, Jacqueline; Kennedy, Charles; Kihara, Yasuyuki; Kinsolving, Julia; Kitazawa, Takio; Kozielewicz, Pawel; Kreienkamp, Hans-Juergen; Kukkonen, Jyrki P.; Laishram, Luxmichan; Langenhan, Tobias; Langmead, Christopher J.; Larhammar, Dan; Leach, Katie; Lecca, Davide; Lee, John D.; Leeman, Susan E.; Leprince, Jerome; Leurs, Rob; Li, Xaria X.; Liebscher, Ines; Lolait, Stephen J.; Lupp, Amelie; Macrae, Robyn; Maguire, Janet J.; Malfacini, Davide; Manning, Maurice; Marangon, Davide; Martemyanov, Kirill; Mazella, Jean; McArdle, Craig A.; Melmed, Shlomo; Michel, Martin C.; Miller, Laurence J.; Mitolo, Vincenzo; Mouillac, Bernard; Mueller, Christa E.; Murphy, Philip M.; Nahon, Jean-Louis; Neubig, Richard R.; Ngo, Tony; Norel, Xavier; Nyimanu, Duuamene; O'Carroll, Anne-Marie; Offermanns, Stefan; Panaro, Maria Antonietta; Parmentier, Marc; Perry-Hauser, Nicole; Pertwee, Roger G.; Pin, Jean-Philippe; Prossnitz, Eric R.; Qin, Helena Chengxue; Quinn, Mark; Raffaele, Stefano; Ramachandran, Rithwik; Ray, Manisha; Reinscheid, Rainer K.; Buzon, Alejandro Romeral; Rondard, Philippe; Rosenkilde, Mette M.; Rovati, G. Enrico; Ruzza, Chiara; Sanger, Gareth J.; Scholz, Nicole; Schoeneberg, Torsten; Schulte, Gunnar; Schulz, Stefan; Segaloff, Deborah L.; Serhan, Charles N.; Shukla, Arun K.; Singh, Khuraijam Dhanachandra; Smith, Craig M.; Smith, Nicola J.; Staeubert, Claudia; Stoddart, Leigh A.; Sugimoto, Yukihiko; Summers, Roger; Tan, Valerie P.; Thal, David M.; Thomas, Walter (Wally); Timmermans, Pieter B. M. W. M.; Tirupula, Kalyan; Toll, Lawrence; Tulipano, Giovanni; Unal, Hamiyet; Unger, Thomas; Valant, Celine; Vanderheyden, Patrick; Vaudry, David; Vaudry, Hubert; Verbalis, Joseph G.; Vilardaga, Jean-Pierre; Walker, Christopher S.; Wang, Ji Ming; Ward, Donald T.; Wester, Hans-Juergen; Willars, Gary B.; Williams, Tom Lloyd; Woodruff, Trent M.; Wu, Huixian; Yang, Cheng; Yao, Chengcan; Ye, Richard D.; Zaidman, Nathan Share Save
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The state of the art in secondary pharmacology and its impact on the safety of new medicines (May, 10.1038/s41573-024-00942-3, 2024) Brennan, Richard J.; Jenkinson, Stephen; Brown, Andrew; Delaunois, Annie; Dumotier, Berengere; Pannirselvam, Malar; Rao, Mohan; Ribeiro, Lyn Rosenbrier; Schmidt, Friedemann; Sibony, Alicia; Timsit, Yoav; Sales, Vicencia Toledo; Armstrong, Duncan; Lagrutta, Armando; Mittlestadt, Scott W.; Naven, Russell; Peri, Ravikumar; Roberts, Sonia; Vergis, James M.; Valentin, Jean-Pierre Share Save
The state of the art in secondary pharmacology and its impact on the safety of new medicines Brennan, Richard J.; Jenkinson, Stephen; Brown, Andrew; Delaunois, Annie; Dumotier, Berengere; Pannirselvam, Malar; Rao, Mohan; Ribeiro, Lyn Rosenbrier; Schmidt, Friedemann; Sibony, Alicia; Timsit, Yoav; Sales, Vicencia Toledo; Armstrong, Duncan; Lagrutta, Armando; Mittlestadt, Scott W.; Naven, Russell; Peri, Ravikumar; Roberts, Sonia; Vergis, James M.; Valentin, Jean-Pierre Share Save
CardioMotion: identification of functional and structural cardiotoxic liabilities in small molecules through brightfield kinetic imaging Stebbeds, William; Raniga, Kavita; Standing, David; Wallace, Iona; Bayliss, James; Brown, Andrew; Kasprowicz, Richard; Dalmas Wilk, Deidre; Deakyne, Julianna; Clements, Peter; Chaudhary, Khuram W.; Rossman, Eric, I; Bahinski, Anthony; Francis, Jo Share Save
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A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signalling pathways in sensory nerves in vivo Gangadharan, Vijayan; Selvaraj, Deepitha; Kurejova, Martina; Njoo, Christian; Gritsch, Simon; Skoricova, Dagmar; Horstmann, Heinz; Offermanns, Stefan; Brown, Andrew J.; Kuner, Thomas; Tappe-Theodor, Anke; Kuner, Rohini Share Save
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GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils (vol 21, pg 1452, 2011) Balenga, Nariman A. B.; Aflaki, Elma; Kargl, Julia; Platzer, Wolfgang; Schroeder, Ralf; Blaettermann, Stefanie; Kostenis, Evi; Brown, Andrew J.; Heinemann, Akos; Waldhoer, Maria Share Save
GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils Balenga, Nariman A. B.; Aflaki, Elma; Kargl, Julia; Platzer, Wolfgang; Schroeder, Ralf; Blaettermann, Stefanie; Kostenis, Evi; Brown, Andrew J.; Heinemann, Akos; Waldhoer, Maria Share Save
Pharmacology of GPR55 in Yeast and Identification of GSK494581A as a Mixed-Activity Glycine Transporter Subtype 1 Inhibitor and GPR55 Agonist Brown, Andrew J.; Daniels, Dion A.; Kassim, Mumta; Brown, Sue; Haslam, Carl P.; Terrell, Victoria R.; Brown, Jason; Nichols, Paula L.; Staton, Penny C.; Wise, Alan; Dowell, Simon J. Share Save
Discovery of 1-[4-(3-Chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a Brain Penetrant 5-Azaindole CB2 Agonist for the Treatment of Chronic Pain Giblin, Gerard M. P.; Billinton, Andrew; Briggs, Michael; Brown, Andrew J.; Chessell, Iain P.; Clayton, Nick M.; Eatherton, Andrew J.; Goldsmith, Paul; Haslam, Carl; Johnson, Matthew R.; Mitchell, William L.; Naylor, Alan; Perboni, Alcide; Slingsby, Brian P.; Wilson, Alex W. Share Save
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The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects Johns, D. G.; Behm, D. J.; Walker, D. J.; Ao, Z.; Shapland, E. M.; Daniels, D. A.; Riddick, M.; Dowell, S.; Staton, P. C.; Green, P.; Shabon, U.; Bao, W.; Aiyar, N.; Yue, T-L; Brown, A. J.; Morrison, A. D.; Douglas, S. A. Share Save
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The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain Staton, Penny C.; Hatcher, Jon P.; Walker, Deborah J.; Morrison, Alastair D.; Shapland, Ellen M.; Hughes, Jane P.; Chong, Elizabeth; Mander, Palwinder K.; Green, Paula J.; Billinton, Andy; Fulleylove, Michael; Lancaster, Hilary C.; Smith, Jason C.; Bailey, Leigh T.; Wise, Alan; Brown, Andrew J.; Richardson, Jill C.; Chessell, Iain P. Share Save
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