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K

Kenneth A. Jacobson

national institutes of health

117H-index
1.3KPaper Count
6.6WCitation Count
Published Papers 518
Publication Date
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Perturbing O-GlcNAcase Modulates the Expression and Distribution of Galectin-3
errCells
IF5.2
err2026-08-06
err0
errOAAI
errMana Mohan Mukherjee; Asmita Pramanik; Marcella Kolodrubetz; Devin Biesbrock; Kenneth A. Jacobson; John A. Hanover
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MRS2339, a cardiac P2X4 receptor nucleotide activator, improves systolic function in heart failure
errMedicinal Chemistry Research
IF3.1
err2026-05-21
err0
errOAAI
errRonghua Yang; Chunxia Cronin; Khaled Qanud; T. Santhosh Kumar; Thomas Hintze; Fabio A. Recchia; Stanko S. Stojilkovic; Claudio Coddou; Kenneth A. Jacobson; Bruce T. Liang
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Novel P2X4 Receptor Antagonist MRS4719 Improves Ischemia/reperfusion Injury in Mice
errMedicinal Chemistry Research
IF3.1
err2026-04-25
err0
PREAI
errRajkumar Verma; Jinting Zhang; Sanjeev Kumar Yadav; Jianlin Feng; Chunxia C. Cronin; Daylin Gamiotea-Turro; Kiran S. Toti; Zhiwei Wen; Kenneth A. Jacobson; Bruce T Liang
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Methodological guidelines for P2X receptor assays and data interpretation
errCell Death & Disease
IF9.6
err2026-04-20
err0
errOAAI
errDariusz C. Gorecki; Elena Adinolfi; Sahil Adriouch; Robson Coutinho-Silva; Tobias Engel; Flóra Gölöncsér; Friedrich Haag; Peter Illes; Kenneth A. Jacobson; Friedrich Koch-Nolte; Steven E. Mansoor; Carlos Matute; Gerry Melino; Ivana Novak; Anna Pegoraro; Pablo Pelegrin; Mauro Piacentini; Simon C. Robson; Robin M. H. Rumney; Michel Seman; Ronald Sluyter; Beáta Sperlagh; Yong Tang; Mario Tarantini; Henning Ulrich; Valerie Vouret-Craviari; Qing Ye; Gennady G. Yegutkin; Alexei Verkhratsky
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From empirical screening to lipid trolling: the evolution of extrahelical allosteric modulators of A1 and A3 adenosine receptors
errMedicinal Chemistry Research
IF3.1
err2026-03-16
err0
errOAAI
errMatteo Pavan; Siva Hariprasad Kurma; Paola Oliva; David P. Broughton; Zhan-Guo Gao; John A. Auchampach; Kenneth A. Jacobson
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errSave
Fluorine-18-Labeled Nucleotide Analogs Targeting Ecto-5'-Nucleotidase (CD73) for Positron Emission Tomography Imaging of Solid Tumors
errAngewandte Chemie International Edition
IF16.9
err2026-03-15
err0
errOAAI
errClemens Dobelmann; Constanze C. Schmies; Georg Wilhelm Rolshoven; Mirko Scortichini; Stefan Wagner; Andreas Isaak; Riham M. Idris; Jennifer Dabel; Lucie Grey; Karolina Losenkova; Susanne Moschütz; Haneen Al Hroub; Antje Keim; Sandra Höppner; Jouko Sandholm; Pia Boström; Maija Hollmén; Norbert Sträter; Sven Hermann; Gennady G. Yegutkin; Kenneth A. Jacobson; Sonja Schelhaas; Christa E. Müller; Anna Junker
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(N)-Methanocarba Adenosine Derivatives as Dual Modulators of P-Glycoprotein and ABCG2 Transporters
errJournal of Medicinal Chemistry
IF6.8
err2026-02-01
err0
PREAI
errMurakami, Megumi; Tosh, Dilip K.; Salazar, Paula B.; Jacobson, Kenneth A.; Ambudkar, Suresh V.
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The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors
errBritish Journal of Pharmacology
IF7.7
err2025-12-01
err29
errOAAI
errAlexander, Stephen P. H.; Davenport, Anthony P.; Kelly, Eamonn; Gibb, Alasdair J.; Mathie, Alistair A.; Peach, Chloe J.; Veale, Emma L.; Armstrong, Jane F.; Faccenda, Elena; Harding, Simon D.; Southan, Christopher; Davies, Jamie A.; Abbracchio, Maria Pia; Abraham, George R.; Agoulnik, Alexander; Alexander, Wayne; Al-hosaini, Khaled; Back, Magnus; Baker, Jillian G.; Barnes, Nicholas M.; Bathgate, Ross; Beaulieu, Jean-Martin; Beck-Sickinger, Annette G.; Behrens, Maik; Bennett, Kirstie A.; Bernstein, Kenneth E.; Bettler, Bernhard; Birdsall, Nigel J. M.; Blaho, Victoria A.; Bonaventure, Pascal; Boulay, Francois; Bousquet, Corinne; Brauner-Osborne, Hans; Brown, Andrew J.; Burnstock, Geoffrey; Busnelli, Marta; Calo, Girolamo; Caruso, Vanni; Castano, Justo P.; Catt, Kevin J.; Ceruti, Stefania; Chazot, Paul; Chiang, Nan; Chini, Bice; Christopoulos, Arthur; Chun, Jerold; Cianciulli, Antonia; Civelli, Olivier; Clapp, Lucie H.; Couture, Rejean; Cox, Helen M.; Csaba, Zsolt; Dahlgren, Claes; Dautzenberg, Frank M.; Dent, Gordon; Douglas, Steven D.; Dournaud, Pascal; Dubocovich, Margarita L.; Eguchi, Satoru; Escher, Emanuel; Filardo, Edward J.; Fong, Tung; Forsman, Huamei Fu; Fumagalli, Marta; Gainetdinov, Raul R.; Garelja, Michael L.; de Gasparo, Marc; Gbahou, Florence; Gerard, Craig; Gershengorn, Marvin; Glass, Michelle; Gloriam, David E.; Gobeil, Fernand; Goodfriend, Theodore L.; Goudet, Cyril; Gratz, Lukas; Gregory, Karen J.; Gruber, Christian; Gundlach, Andrew L.; Hamann, Jorg; Hanson, Julien; Hartman, Deborah S.; Hauger, Richard L.; Hay, Debbie L.; Heinemann, Akos; Heitman, Laura; Herr, Deron R.; Hollenberg, Morley D.; Holliday, Nicholas D.; Holst, Birgitte; Horiuchi, Mastgugu; Hoyer, Daniel; Hunyady, Laszlo; Husain, Ahsan; IJzerman, Adriaan P.; Inagami, Tadashi; Insel, Paul A.; Jacobson, Kenneth A.; Jacobson, Laura H.; Jensen, Robert T.; Jockers, Ralf; Jonnalagadda, Deepa; Karnik, Sadashiva; Kaupmann, Klemens; Kemp, Jacqueline; Kennedy, Charles; Kihara, Yasuyuki; Kinsolving, Julia; Kitazawa, Takio; Kozielewicz, Pawel; Kreienkamp, Hans-Juergen; Kukkonen, Jyrki P.; Laishram, Luxmichan; Langenhan, Tobias; Langmead, Christopher J.; Larhammar, Dan; Leach, Katie; Lecca, Davide; Lee, John D.; Leeman, Susan E.; Leprince, Jerome; Leurs, Rob; Li, Xaria X.; Liebscher, Ines; Lolait, Stephen J.; Lupp, Amelie; Macrae, Robyn; Maguire, Janet J.; Malfacini, Davide; Manning, Maurice; Marangon, Davide; Martemyanov, Kirill; Mazella, Jean; McArdle, Craig A.; Melmed, Shlomo; Michel, Martin C.; Miller, Laurence J.; Mitolo, Vincenzo; Mouillac, Bernard; Mueller, Christa E.; Murphy, Philip M.; Nahon, Jean-Louis; Neubig, Richard R.; Ngo, Tony; Norel, Xavier; Nyimanu, Duuamene; O'Carroll, Anne-Marie; Offermanns, Stefan; Panaro, Maria Antonietta; Parmentier, Marc; Perry-Hauser, Nicole; Pertwee, Roger G.; Pin, Jean-Philippe; Prossnitz, Eric R.; Qin, Helena Chengxue; Quinn, Mark; Raffaele, Stefano; Ramachandran, Rithwik; Ray, Manisha; Reinscheid, Rainer K.; Buzon, Alejandro Romeral; Rondard, Philippe; Rosenkilde, Mette M.; Rovati, G. Enrico; Ruzza, Chiara; Sanger, Gareth J.; Scholz, Nicole; Schoeneberg, Torsten; Schulte, Gunnar; Schulz, Stefan; Segaloff, Deborah L.; Serhan, Charles N.; Shukla, Arun K.; Singh, Khuraijam Dhanachandra; Smith, Craig M.; Smith, Nicola J.; Staeubert, Claudia; Stoddart, Leigh A.; Sugimoto, Yukihiko; Summers, Roger; Tan, Valerie P.; Thal, David M.; Thomas, Walter (Wally); Timmermans, Pieter B. M. W. M.; Tirupula, Kalyan; Toll, Lawrence; Tulipano, Giovanni; Unal, Hamiyet; Unger, Thomas; Valant, Celine; Vanderheyden, Patrick; Vaudry, David; Vaudry, Hubert; Verbalis, Joseph G.; Vilardaga, Jean-Pierre; Walker, Christopher S.; Wang, Ji Ming; Ward, Donald T.; Wester, Hans-Juergen; Willars, Gary B.; Williams, Tom Lloyd; Woodruff, Trent M.; Wu, Huixian; Yang, Cheng; Yao, Chengcan; Ye, Richard D.; Zaidman, Nathan
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UDP-glucose and MRS2905 agonist-bound states of the purinergic P2Y14 receptor
errCommunications Biology
IF5.1
err2025-11-21
err0
errOAAI
errJonathan F. Fay; Joseph Kousouros; Zhan-Guo Gao; Matteo Pavan; Paola Oliva; Asmita Pramanik; Clayton Meyer; Siva Hariprasad Kurma; Wen Xu; Brian Krumm; Kenneth A. Jacobson
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IMMU-82. Neuronal modulation of immunity in glioblastoma
errNeuro-Oncology
IF13.4
err2025-11-11
err0
errOAAI
errJohn C Hancock; Qiuchen Zhao; Tyler Shaw; Jonathan Seaman; Nicole Briceno; Matteo Pavan; Paola Olivia; Jihyun Lee; Huw Naylor; Matthaios Pitoulias; Venkat Pisupati; Kamal Kishore; Luca Porcu; Alexander Y Mitrophanov; Manuela Natoli; Jodi Miller; Miguel Santos; Meili Zhang; Dionne Davis; Wei Zhang; Hua Song; Jo Spurgeon; Hye Kim; Ayaka Hara; Caitlin Huguely; Brita Anderson; Emily Steffke; Seketoulie Keretsu; Alexander T Chesler; Chunzhang Yang; Hugh Robinson; Kenneth A Jacobson; Mark R Gilbert; Masaki Terabe; Richard Mair
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(N)-Methanocarba-adenosines as monoamine transporter allosteric inhibitors: Extended N6 groups for bitopic stabilization
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-09-19
err0
errOAAI
errDilip K. Tosh; Matteo Pavan; Laura B. Kozell; Amy J. Eshleman; Jennifer L. Schmachtenberg; Katherine M. Wolfrum; William E. Schutzer; Atheir I. Abbas; Kenneth A. Jacobson
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Development and Preclinical Evaluation of PET Radiotracers Targeting Adenosine A1 Receptors
errACS Medicinal Chemistry Letters
IF4
err2025-06-26
err0
PREAI
errAbolghasem Gus Bakhoda; Torben D. Pearson; Zhan-Guo Gao; Kelly A. O’Conor; Seth M. Eisenberg; Andrew C. Kelleher; Yeona Kang; Jeih-San Liow; Jun Yong Choi; Woochan Kim; Jinpyo Seo; Michael L. Freaney; Kenneth A. Jacobson; Nora D. Volkow; Sung Won Kim
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Structure-Activity Relationship Analysis of 2-Aryl-8-alkynyl Adenine and Nucleoside Scaffolds as A3 Adenosine Receptor Ligands
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2025-04-01
err0
PREAI
errKim, Gibae; Lee, Grim; Jarhad, Dnyandev B.; Gao, Zhan-Guo; Kim, Seung Woo; Joung, Misuk; Jacobson, Kenneth A.; Jeong, Lak Shin
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E. B. Hershberg Award: Taming Inflammation by Tuning Purinergic Signaling
errACCOUNTS OF CHEMICAL RESEARCH
IF17.7
err2025-03-05
err0
PREAI
errJacobson, KA
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Adenosine A3 Receptor Agonism Attenuates Chronic Nitroglycerin-Induced Migraine-Like Trigeminal Hypersensitivity in Mice via T-Cells/IL-10 Mediated Response
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errMichalski, Stephanie A.; Galen, Karen; Jones, Spencer; Romero-reyes, Marcela; Jacobson, Kenneth; Akerman, Simon; Salvemini, Daniela
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Purinergic Signaling in Paclitaxel-Induced Cognitive Impairment in a Mouse Model of Breast Cancer
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errBrown, Jennifer; Squillace, Silvia; Galen, Karen; Jacobson, Kenneth; Farr, Susan; Salvemini, Daniela
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errSave
A2B adenosine receptor-triggered intracellular calcium mobilization: Cell type-dependent involvement of Gi, Gq, Gs proteins and protein kinase C
errPURINERGIC SIGNALLING
IF2.4
err2025-02-11
err0
errOAAI
errGao, Zhan-Guo; Gao, Ray R.; Meyer, Clayton K.; Jacobson, Kenneth A.
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Third-Generation CD73 Inhibitors Based on a 4,6-Disubstituted-2-Thiopyridine Scaffold
errCHEMMEDCHEM
IF3.4
err2025-01-02
err0
errOAAI
errGrosjean, Felix; Shaldaeva, Maria; Cros-Perrial, Emeline; Rodriguez, Celine; Ghoteimi, Rayane; Lebrun, Aurelien; Gao, Zhan-Guo; Uttaro, Jean-Pierre; Mathe, Christophe; Jacobson, Kenneth A.; Petter Jordheim, Lars; Menetrier-Caux, Christine; Chaloin, Laurent; Peyrottes, Suzanne
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Abraham Patchornik: The Contemporary Relevance of His Work for Chemistry and Biology
errJACS AU
IF8.7
err2024-12-20
err0
errOAAI
errJacobson, Kenneth A.; Ellis-Davies, Graham C. R.
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Photoswitchable Diazocine Derivative for Adenosine A3 Receptor Activation in Psoriasis
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-12-16
err0
errOAAI
errLopez-Cano, Marc; Scortichini, Mirko; Tosh, Dilip K.; Salmaso, Veronica; Ko, Tongil; Salort, Gloria; Filgaira, Ingrid; Soler, Concepcio; Trauner, Dirk; Hernando, Jordi; Jacobson, Kenneth A.; Ciruela, Francisco
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Research Directions

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Co-authors
Cooperation Journals
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Frank J. Gonzalez
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Charles N. Serhan
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Nora D. Volkow
H-index: 170 · Papers: 1.3K
G
Geoffrey Burnstock
H-index: 141 · Papers: 1.4K
C
Claudio Franceschi
H-index: 136 · Papers: 1.2K
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