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J

Jonas Emsley

School of Pharmacy

44H-index
186Paper Count
7.6KCitation Count
Published Papers 72
Publication Date
On-demand peptide therapeutics for multi-year space exploration: analysis of clinical and operational relevance and recombinant production feasibility
err2026-07-09
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errJohn J. Donovan; Isaac Ericson; Andrew Wenthe; Katalin Kovacs; Jonas Emsley; Philip M. Williams
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Structure and interactions of the proteins from the contact system
errBlood
IF23.1
err2025-07-12
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PREAI
errJonas Emsley; Yujie Ma; Joost C. M. Meijers
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Crystal structure of coagulation factor XII N-terminal domains 1-5
err2025-07-01
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errSaleem, Muhammad; Li, Chan; Kaira, Bubacarr G.; Brown, Alexander K.; Pathak, Monika; Najmudin, Shabir; Cowieson, Nathan; Dreveny, Ingrid; Wilson, Clare; Shamanaev, Aleksandr; Gailani, David; Smith, Stephanie A.; Morrissey, James H.; Philippou, Helen; Emsley, Jonas
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Epithelial Interleukin-1 Receptor-Like-1 Activation Is Contingent on Interleukin-33 Isoforms and Asthma-Related Receptor Variation
err2024-09-20
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errPortelli, Michael A.; Ketelaar, Maria E.; Bates, Stewart; Csomor, Eszter; Shaw, Dominick; Emsley, Jonas; Brightling, Christopher; Hall, Ian; Affleck, Karen; Edwards, Matthew; Nawijn, Martijn C.; Koppelman, Gerard H.; Van Oosterhout, Antoon J.; Sayers, Ian
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Discovery of α-Amidobenzylboronates as Highly Potent Covalent Inhibitors of Plasma Kallikrein
err2024-03-28
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errAllison, Matthew; Davie, Rebecca L.; Mogg, Adrian J.; Hampton, Sally L.; Emsley, Jonas; Stocks, Michael J.
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Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections
err2024-01-03
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errSoukarieh, Fadi; Mashabi, Alaa; Richardson, William; Oton, Eduard Vico; Romero, Manuel; Dubern, Jean-Frederic; Robertson, Shaun N.; Lucanto, Simone; Markham-Lee, Zoe; Sou, Tomas; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Bergstrom, Christel A. S.; Halliday, Nigel; Kellam, Barrie; Emsley, Jonas; Heeb, Stephan; Williams, Paul; Stocks, Michael J.; Camara, Miguel
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High molecular weight kininogen interactions with the homologs prekallikrein and factor XI: importance to surface-induced coagulation
err2024-01-01
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errOAAI
errMohammed, Bassem M.; Sun, Mao-fu; Cheng, Qiufang; Litvak, Maxim; Mccrae, Keith R.; Emsley, Jonas; Mccarty, Owen J. T.; Gailani, David
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Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity
err2023-11-01
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errMaurer, Sigrun K.; Mayer, Matthias P.; Ward, Stephanie J.; Boudjema, Sana; Halawa, Mohamed; Zhang, Jiatong; Caulton, Simon G.; Emsley, Jonas; Dreveny, Ingrid
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Structures of factor XI and prekallikrein bound to domain 6 of high-molecular weight kininogen reveal alternate domain 6 conformations and exosites
err2023-09-01
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errOAAI
errLi, Chan; Barroeta, Awital Bar; Wong, Szu Shen; Kim, Hyo Jung; Pathak, Monika; Dreveny, Ingrid; Meijers, Joost C. M.; Emsley, Jonas
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Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate
err2023-05-05
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errBardelang, Philip; Murray, Ewan J.; Blower, Isobel; Zandomeneghi, Sara; Goode, Alice; Hussain, Rohanah; Kumari, Divya; Siligardi, Giuliano; Inoue, Katsuaki; Luckett, Jeni; Doutch, James; Emsley, Jonas; Chan, Weng C.; Hill, Philip; Williams, Paul; Bonev, Boyan B.
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Plasma Kallikrein as a Forgotten Clotting Factor
err2023-04-18
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PREAI
errKearney, Katherine J.; Spronk, Henri M. H.; Emsley, Jonas; Key, Nigel S.; Philippou, Helen
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Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization
err2023-02-01
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errDamaskinaki, Foteini-Nafsika; Jooss, Natalie J.; Martin, Eleyna M.; Clark, Joanne C.; Thomas, Mark R.; Poulter, Natalie S.; Emsley, Jonas; Kellam, Barrie; Watson, Steve P.; Slater, Alexandre
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Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa
err2021-08-17
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errSoukarieh, Fadi; Mashabi, Alaa; Richardson, William; Oton, Eduard Vico; Romero, Manuel; Roberston, Shaun N.; Grossman, Scott; Sou, Tomas; Liu, Ruiling; Halliday, Nigel; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Bergstrom, Christel A. S.; Kellam, Barrie; Emsley, Jonas; Heeb, Stephan; Williams, Paul; Stocks, Michael J.; Camara, Miguel
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Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module
err2021-04-21
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errArce, Nicholas A.; Cao, Wenpeng; Brown, Alexander K.; Legan, Emily R.; Wilson, Moriah S.; Xu, Emma-Ruoqi; Berndt, Michael C.; Emsley, Jonas; Zhang, X. Frank; Li, Renhao
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Crystal structure of ADAMTS13 CUB domains reveals their role in global latency
err2021-04-16
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errKim, H. J.; Xu, Y.; Petri, A.; Vanhoorelbeke, K.; Crawley, J. T. B.; Emsley, J.
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Thrombin in the Activation of the Fluid Contact Phase in Patients with Hereditary Angioedema Carrying the F12 P.Thr309Lys Variant
err2021-03-16
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PREAI
errLopez-Galvez, R.; de la Morena-Barrio, M. E.; Minano, A.; Pathak, M.; Marcos, C.; Emsley, J.; Caballero, T.; Lopez-Trascasa, M.; Vicente, V.; Corral, J.; Lopez-Lera, A.
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Proteolytic activity of contact factor zymogens
err2021-02-01
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errShamanaev, Aleksandr; Emsley, Jonas; Gailani, David
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Structural assessment of SARS-CoV2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential
err2021-01-08
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errNizamudeen, Zubair Ahmed; Xu, Emma-Ruoqi; Karthik, Vivin; Halawa, Mohamed; Arkill, Kenton P.; Jackson, Andrew M.; Bates, David O.; Emsley, Jonas
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The evolution of factor XI and the kallikrein-kinin system
err2020-12-11
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errPonczek, Michal B.; Shamanaev, Aleksandr; LaPlace, Alec; Dickeson, S. Kent; Srivastava, Priyanka; Sun, Mao-fu; Gruber, Andras; Kastrup, Christian; Emsley, Jonas; Gailani, David
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Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR
err2020-12-01
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errGrossman, Scott; Soukarieh, Fadi; Richardson, William; Liu, Ruiling; Mashabi, Alaa; Emsley, Jonas; Williams, Paul; Camara, Miguel; Stocks, Michael J.
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