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SaveShare Save Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling
Regnier, Marion; Polizzi, Arnaud; Fougeray, Tiffany; Fougerat, Anne; Perrier, Prunelle; Anderson, Karen; Lippi, Yannick; Smati, Sarra; Lukowicz, Celine; Lasserre, Frederic; Fouche, Edwin; Huillet, Marine; Rives, Clemence; Tramunt, Blandine; Naylies, Claire; Garcia, Geraldine; Rousseau-Bacquie, Elodie; Bertrand-Michel, Justine; Canlet, Cecile; Chevolleau-Mege, Sylvie; Debrauwer, Laurent; Heymes, Christophe; Burcelin, Remy; Levade, Thierry; Gourdy, Pierre; Wahli, Walter; Blum, Yuna; Gamet-Payrastre, Laurence; Ellero-Simatos, Sandrine; Guillermet-Guibert, Julie; Hawkins, Phillip; Stephens, Len; Postic, Catherine; Montagner, Alexandra; Loiseau, Nicolas; Guillou, Herve Share Save Repeated fasting events sensitize enhancers, transcription factor activity and gene expression to support augmented ketogenesisKorenfeld, Noga; Charni-Natan, Meital; Bruse, Justine; Goldberg, Dana; Marciano-Anaki, Dorin; Rotaro, Dan; Gorbonos, Tali; Radushkevitz-Frishman, Talia; Polizzi, Arnaud; Nasereddin, Abed; Gover, Ofer; Bar-Shimon, Meirav; Fougerat, Anne; Guillou, Herve; Goldstein, Ido Share Save Association between dietary pesticide exposure profiles and body weight change in French adults: Results from the NutriNet-Sante cohortBerlivet, Justine; Payrastre, Laurence; Rebouillat, Pauline; Fougerat, Anne; Touvier, Mathilde; Hercberg, Serge; Lairon, Denis; Pointereau, Philippe; Guillou, Herve; Vidal, Rodolphe; Baudry, Julia; Kesse-Guyot, Emmanuelle Share Save Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolismHuillet, Marine; Lasserre, Frederic; Gratacap, Marie-Pierre; Engelmann, Beatrice; Bruse, Justine; Polizzi, Arnaud; Fougeray, Tiffany; Martin, Celine Marie Pauline; Rives, Clemence; Fougerat, Anne; Naylies, Claire; Lippi, Yannick; Garcia, Geraldine; Rousseau-Bacquie, Elodie; Canlet, Cecile; Debrauwer, Laurent; Rolle-Kampczyk, Ulrike; von Bergen, Martin; Payrastre, Bernard; Boutet-Robinet, Elisa; Gamet-Payrastre, Laurence; Guillou, Herve; Loiseau, Nicolas; Ellero-Simatos, Sandrine Share Save Obesity promotes fumonisin B1 hepatotoxicityDopavogui, Leonie; Regnier, Marion; Polizzi, Arnaud; Ponchon, Quentin; Smati, Sarra; Klement, Wendy; Lasserre, Frederic; Lukowicz, Celine; Lippi, Yannick; Fougerat, Anne; Bertrand-Michel, Justine; Naylies, Claire; Canlet, Cecile; Debrauwer, Laurent; Rousseau-Bacquie, Elodie; Gamet-Payrastre, Laurence; Dauriat, Charlene; Casas, Josefina; Croubels, Siska; De Baere, Siegrid; Burger, Hester M.; Chassaing, Benoit; Ellero-Simatos, Sandrine; Guillou, Herve; Oswald, Isabelle P.; Loiseau, Nicolas Share Save ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activityFougerat, Anne; Schoiswohl, Gabriele; Polizzi, Arnaud; Regnier, Marion; Wagner, Carina; Smati, Sarra; Fougeray, Tiffany; Lippi, Yannick; Lasserre, Frederic; Raho, Ilyes; Melin, Valentine; Tramunt, Blandine; Metivier, Raphael; Sommer, Caroline; Benhamed, Fadila; Alkhoury, Chantal; Greulich, Franziska; Jouffe, Celine; Emile, Anthony; Schupp, Michael; Gourdy, Pierre; Dubot, Patricia; Levade, Thierry; Meynard, Delphine; Ellero-Simatos, Sandrine; Gamet-Payrastre, Laurence; Panasyuk, Ganna; Uhlenhaut, Henriette; Amri, Ez-Zoubir; Cruciani-Guglielmacci, Celine; Postic, Catherine; Wahli, Walter; Loiseau, Nicolas; Montagner, Alexandra; Langin, Dominique; Lass, Achim; Guillou, Herve Share Save The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expressionFougeray, Tiffany; Polizzi, Arnaud; Regnier, Marion; Fougerat, Anne; Ellero-Simatos, Sandrine; Lippi, Yannick; Smati, Sarra; Lasserre, Frederic; Tramunt, Blandine; Huillet, Marine; Dopavogui, Leonie; Salvi, Juliette; Nedelec, Emmanuelle; Gigot, Vincent; Smith, Lorraine; Naylies, Claire; Sommer, Caroline; Haas, Joel T.; Wahli, Walter; Duez, Helene; Gourdy, Pierre; Gamet-Payrastre, Laurence; Benani, Alexandre; Burnol, Anne-Francoise; Loiseau, Nicolas; Postic, Catherine; Montagner, Alexandra; Guillou, Herve Share Save Tissular Genomic Responses to Oral FB1 Exposure in PigsDopavogui, Leonie; Polizzi, Arnaud; Fougerat, Anne; Gourbeyre, Pascal; Terciolo, Chloe; Klement, Wendy; Pinton, Philippe; Laffite, Joelle; Cossalter, Anne-Marie; Bailly, Jean-Denis; Puel, Olivier; Lippi, Yannick; Naylies, Claire; Guillou, Herve; Oswald, Isabelle P.; Loiseau, Nicolas Share Save The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in miceBarretto, Sharon Ann; Lasserre, Frederic; Huillet, Marine; Regnier, Marion; Polizzi, Arnaud; Lippi, Yannick; Fougerat, Anne; Person, Elodie; Bruel, Sandrine; Betoulieres, Colette; Naylies, Claire; Lukowicz, Celine; Smati, Sarra; Guzylack, Laurence; Olier, Maiwenn; Theodorou, Vassilia; Mselli-Lakhal, Laila; Zalko, Daniel; Wahli, Walter; Loiseau, Nicolas; Gamet-Payrastre, Laurence; Guillou, Herve; Ellero-Simatos, Sandrine Share Save Neuraminidases 1 and 3 Trigger Atherosclerosis by Desialylating Low-Density Lipoproteins and Increasing Their Uptake by MacrophagesDemina, Ekaterina P.; Smutova, Victoria; Pan, Xuefang; Fougerat, Anne; Guo, Tianlin; Zou, Chunxia; Chakraberty, Radhika; Snarr, Brendan D.; Shiao, Tze C.; Roy, Rene; Orekhov, Alexander N.; Miyagi, Taeko; Laffargue, Muriel; Sheppard, Donald C.; Cairo, Christopher W.; Pshezhetsky, Alexey, V Share Save Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J miceSmith, Lorraine; Klement, Wendy; Dopavogui, Leonie; de Bock, Frederic; Lasserre, Frederic; Barretto, Sharon; Lukowicz, Celine; Fougerat, Anne; Polizzi, Arnaud; Schaal, Benoist; Patris, Bruno; Denis, Colette; Feuillet, Guylene; Canlet, Cecile; Jamin, Emilien L.; Debrauwer, Laurent; Mselli-Lakhal, Laila; Loiseau, Nicolas; Guillou, Herve; Marchi, Nicola; Ellero-Simatos, Sandrine; Gamet-Payrastre, Laurence Share Save Share Save Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesityRegnier, Marion; Polizzi, Arnaud; Smati, Sarra; Lukowicz, Celine; Fougerat, Anne; Lippi, Yannick; Fouche, Edwin; Lasserre, Frederic; Naylies, Claire; Betoulieres, Colette; Barquissau, Valentin; Mouisel, Etienne; Bertrand-Michel, Justine; Batut, Aurelie; Al Saati, Talal; Canlet, Cecile; Tremblay-Franco, Marie; Ellero-Simatos, Sandrine; Langin, Dominique; Postic, Catherine; Wahli, Walter; Loiseau, Nicolas; Guillou, Herve; Montagner, Alexandra Share Save Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptor (vol 9, 20169, 2019)Lukowicz, Celine; Ellero-Simatos, Sandrine; Regnier, Marion; Oliviero, Fabiana; Lasserre, Frederic; Polizzi, Arnaud; Montagner, Alexandra; Smati, Sarra; Boudou, Frederic; Lenfant, Francoise; Guzylack-Pirou, Laurence; Menard, Sandrine; Barretto, Sharon; Fougerat, Anne; Lippi, Yannick; Naylies, Claire; Bertrand-Michel, Justine; Belgnaoui, Afifa Ait; Theodorou, Vassilia; Marchi, Nicola; Gourdy, Pierre; Gamet-Payrastre, Laurence; Loiseau, Nicolas; Guillou, Herve; Mselli-Lakhal, Laila Share Save Dimorphic metabolic and endocrine disorders in mice lacking the constitutive androstane receptorLukowicz, Celine; Ellero-Simatos, Sandrine; Regnier, Marion; Oliviero, Fabiana; Lasserre, Frederic; Polizzi, Arnaud; Montagner, Alexandra; Smati, Sarra; Boudou, Frederic; Lenfant, Francoise; Guzylack-Pirou, Laurence; Menard, Sandrine; Barretto, Sharon; Fougerat, Anne; Lippi, Yannick; Naylies, Claire; Bertrand-Michel, Justine; Belgnaoui, Afifa Ait; Theodorou, Vassilia; Marchi, Nicola; Gourdy, Pierre; Gamet-Payrastre, Laurence; Loiseau, Nicolas; Guillou, Herve; Mselli-Lakhal, Laila Share Save Share Save Selective Inhibitors of Human Neuraminidase 3Guo, Tianlin; Datwyler, Philipp; Demina, Ekaterina; Richards, Michele R.; Ge, Peng; Zou, Chunxia; Zheng, Ruixiang; Fougerat, Anne; Pshezhetsky, Alexey V.; Ernst, Beat; Cairo, Christopher W. 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