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J

Jacques J. Kessl

university of southern mississippi

26H-index
47Paper Count
2.6KCitation Count
Published Papers 31
Publication Date
Mapping the TAR vRNA Interaction with HIV-1 Integrase
errViruses
IF3.5
err2026-06-09
err0
errOAAI
errJian Sun; Rahul Yadav; Tolga Catmakas; Luke Fisher; Nicholas C. Fitzkee; Jacques J. Kessl
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Exploring Residue-Level Interactions between the Biofilm-Driving R2ab Protein and Polystyrene Nanoparticles
err2024-01-04
err0
PREAI
errSomarathne, Radha P.; Misra, Sandeep K.; Kariyawasam, Chathuri S.; Kessl, Jacques J.; Sharp, Joshua S.; Fitzkee, Nicholas C.
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Multi-Substituted Quinolines as HIV-1 Integrase Allosteric Inhibitors
err2022-07-02
err6
errOAAI
errLong Phi Dinh; Sun, Jian; Glenn, Courtney D.; Patel, Krunal; Pigza, Julie A.; Donahue, Matthew G.; Yet, Larry; Kessl, Jacques J.
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Identification and Optimization of a Novel HIV-1 Integrase Inhibitor
err2022-01-24
err6
errOAAI
errAdu-Ampratwum, Daniel; Pan, Yuhan; Koneru, Pratibha C.; Antwi, Janet; Hoyte, Ashley C.; Kessl, Jacques; Griffin, Patrick R.; Kvaratskhelia, Mamuka; Fuchs, James R.; Larue, Ross C.
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Optimized binding of substituted quinoline ALLINIs within the HIV-1 integrase oligomer
err2021-01-01
err10
errOAAI
errSun, Jian; Patel, Krunal; Hume, Jared; Pigza, Julie A.; Donahue, Matthew G.; Kessl, Jacques J.
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Synthesis and Evaluation of Aryl Quinolines as HIV-1 Integrase Multimerization Inhibitors
err2018-09-14
err25
errOAAI
errJentsch, Nicholas G.; Hart, Alison P.; Hume, Jared D.; Sun, Jian; McNeely, Kaitlin A.; Lama, Chiyang; Pigza, Julie A.; Donahue, Matthew G.; Kessl, Jacques J.
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HIV-1 Integrase-Targeted Short Peptides Derived from a Viral Protein R Sequence
err2018-07-26
err4
errOAAI
errZhao, Xue Zhi; Metifiot, Mathieu; Kiselev, Evgeny; Kessl, Jacques J.; Maddali, Kasthuraiah; Marchand, Christophe; Kvaratskhelia, Mamuka; Pommier, Yves; Burke, Terrence R., Jr.
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A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain
err2016-11-01
err26
errOAAI
errPatel, Disha; Antwi, Janet; Koneru, Pratibha C.; Serrao, Erik; Forli, Stefano; Kessl, Jacques J.; Feng, Lei; Deng, Nanjie; Levy, Ronald M.; Fuchs, James R.; Olson, Arthur J.; Engelman, Alan N.; Bauman, Joseph D.; Kvaratskhelia, Mamuka; Arnold, Eddy
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The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency
err2016-03-02
err32
errOAAI
errFeng, Lei; Dharmarajan, Venkatasubramanian; Serrao, Erik; Hoyte, Ashley; Larue, Ross C.; Slaughter, Alison; Sharma, Amit; Plumb, Matthew R.; Kessl, Jacques J.; Fuchs, James R.; Bushman, Frederic D.; Engelman, Alan N.; Griffin, Patrick R.; Kvaratskhelia, Mamuka
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A Critical Role of the C-terminal Segment for Allosteric Inhibitor-induced Aberrant Multimerization of HIV-1 Integrase
err2014-09-01
err30
errOAAI
errShkriabai, Nikoloz; Dharmarajan, Venkatasubramanian; Slaughter, Alison; Kessl, Jacques J.; Larue, Ross C.; Feng, Lei; Fuchs, James R.; Griffin, Patrick R.; Kvaratskhelia, Mamuka
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A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase
err2014-05-29
err114
errOAAI
errSharma, Amit; Slaughter, Alison; Jena, Nivedita; Feng, Lei; Kessl, Jacques J.; Fadel, Hind J.; Malani, Nirav; Male, Frances; Wu, Li; Poeschla, Eric; Bushman, Frederic D.; Fuchs, James R.; Kvaratskhelia, Mamuka
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BET proteins promote efficient murine leukemia virus integration at transcription start sites
err2013-07-01
err161
errOAAI
errSharma, Amit; Larue, Ross C.; Plumb, Matthew R.; Malani, Nirav; Male, Frances; Slaughter, Alison; Kessl, Jacques J.; Shkriabai, Nikolozi; Coward, Elizabeth; Aiyer, Sriram S.; Green, Patrick L.; Wu, Li; Roth, Monica J.; Bushman, Frederic D.; Kvaratskhelia, Mamuka
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Allosteric inhibition of HIV-1 integrase activity
err2013-06-01
err71
errOAAI
errEngelman, Alan; Kessl, Jacques J.; Kvaratskhelia, Mamuka
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The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors
err2013-05-01
err93
errOAAI
errFeng, Lei; Sharma, Amit; Slaughter, Alison; Jena, Nivedita; Koh, Yasuhiro; Shkriabai, Nikolozi; Larue, Ross C.; Patel, Pratiq A.; Mitsuya, Hiroaki; Kessl, Jacques J.; Engelman, Alan; Fuchs, James R.; Kvaratskhelia, Mamuka
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Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation
err2013-04-22
err185
errOAAI
errJurado, Kellie A.; Wang, Hao; Slaughter, Alison; Feng, Lei; Kessl, Jacques J.; Koh, Yasuhiro; Wang, Weifeng; Ballandras-Colas, Allison; Patel, Pratiq A.; Fuchs, James R.; Kvaratskhelia, Mamuka; Engelman, Alan
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Interaction of the HIV-1 Intasome with Transportin 3 Protein (TNPO3 or TRN-SR2)
err2012-10-01
err51
errOAAI
errLarue, Ross; Gupta, Kushol; Wuensch, Christiane; Shkriabai, Nikolozi; Kessl, Jacques J.; Danhart, Eric; Feng, Lei; Taltynov, Oliver; Christ, Frauke; Van Duyne, Gregory D.; Debyser, Zeger; Foster, Mark P.; Kvaratskhelia, Mamuka
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Multimode, Cooperative Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors
err2012-05-01
err177
errOAAI
errKessl, Jacques J.; Jena, Nivedita; Koh, Yasuhiro; Taskent-Sezgin, Humeyra; Slaughter, Alison; Feng, Lei; de Silva, Suresh; Wu, Li; Le Grice, Stuart F. J.; Engelman, Alan; Fuchs, James R.; Kvaratskhelia, Mamuka
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FRET analysis reveals distinct conformations of IN tetramers in the presence of viral DNA or LEDGF/p75
err2011-07-19
err56
errOAAI
errKessl, Jacques J.; Li, Min; Ignatov, Michael; Shkriabai, Nikolozi; Eidahl, Jocelyn O.; Feng, Lei; Musier-Forsyth, Karin; Craigie, Robert; Kvaratskhelia, Mamuka
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