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Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors Chafe, Shawn C.; Vizeacoumar, Frederick S.; Venkateswaran, Geetha; Nemirovsky, Oksana; Awrey, Shannon; Brown, Wells S.; McDonald, Paul C.; Carta, Fabrizio; Metcalfe, Andrew; Karasinska, Joanna M.; Huang, Ling; Muthuswamy, Senthil K.; Schaeffer, David F.; Renouf, Daniel J.; Supuran, Claudiu T.; Vizeacoumar, Franco J.; Dedhar, Shoukat Share Save
Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia McDonald, Paul C.; Chafe, Shawn C.; Brown, Wells S.; Saberi, Saeed; Swayampakula, Mridula; Venkateswaran, Geetha; Nemirovsky, Oksana; Gillespie, Jordan A.; Karasinska, Joanna M.; Kalloger, Steve E.; Supuran, Claudiu T.; Schaeffer, David F.; Bashashati, Ali; Shah, Sohrab P.; Topham, James T.; Yapp, Donald T.; Li, Jinyang; Renouf, Daniel J.; Stanger, Ben Z.; Dedhar, Shoukat Share Save
The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion Swayampakula, M.; McDonald, P. C.; Vallejo, M.; Coyaud, E.; Chafe, S. C.; Westerback, A.; Venkateswaran, G.; Shankar, J.; Gao, G.; Laurent, E. M. N.; Lou, Y.; Bennewith, K. L.; Supuran, C. T.; Nabi, I. R.; Raught, B.; Dedhar, S. Share Save
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