Not logged inA bivalent COVID-19 mRNA vaccine elicited broad immune responses and protection against Omicron subvariants infection
Liu, Jun; Wang, Li; Kurtesi, Alexandra; Budylowski, Patrick; Potts, Kyle G.; Menon, Haritha; Tan, Yilin; Samaan, Philip; Liu, Xinan; Wang, Yisen; Hu, Queenie; Samson, Reuben; Qi, Freda; Evseev, Danyel; John, Cini; Ellestad, Kristofor K.; Fan, Yue; Budiman, Frans; Tohan, Ellaine Riczly; Udayakumar, Suji; Yang, Jennifer; Marcusson, Eric G.; Gingras, Anne-Claude; Mahoney, Douglas J.; Ostrowski, Mario A.; Martin-Orozco, Natalia .png)
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SaveDiscovery of Highly Potent and Selective IRAK1 Degraders to Probe Scaffolding Functions of IRAK1 in ABC DLBCLFu, Liqiang; Zhang, Jing; Shen, Bin; Kong, Linglong; Liu, Yingtao; Tu, Wangyang; Wang, Wenqian; Cai, Xin; Wang, Xiaotao; Cheng, Na; Xia, Mingxuan; Zhou, Tianyuan; Liu, Qian; Xu, Yanping; Yang, Jennifer; Gavine, Paul; Philippar, Ulrike; Attar, Ricardo; Edwards, James P.; Venable, Jennifer D.; Dai, Xuedong Share Save Share Save Assessing IRAK4 Functions in ABC DLBCL by IRAK4 Kinase Inhibition and Protein DegradationZhang, Jing; Fu, Liqiang; Shen, Bin; Liu, Yingtao; Wang, Wenqian; Cai, Xin; Kong, Linglong; Yan, Yilin; Meng, Ryan; Zhang, Zhuming; Chen, Ying-Nan P.; Liu, Qian; Wan, Zhao-Kui; Zhou, Tianyuan; Wang, Xiaotao; Gavine, Paul; Del Rosario, Amanda; Ahn, Kay; Philippar, Ulrike; Attar, Ricardo; Yang, Jennifer; Xu, Yanping; Edwards, James P.; Dai, Xuedong Share Save Share Save Suppressive myeloid cells are expanded by biliary tract cancer-derived cytokines in vitro and associate with aggressive diseaseWare, Michael B.; Zaidi, Mohammad Y.; Yang, Jennifer; Turgeon, Michael K.; Krasinskas, Alyssa; Mace, Thomas A.; Keenan, Kaitlin; Farren, Matthew R.; Ruggieri, Amanda N.; Li, Yiman; Zhang, Chao; Chen, Zhengjia; Young, Gregory S.; Elnaggar, Omar; Che, Zheng; Maithel, Shishir K.; Bekaii-Saab, Tanios; El-Rayes, Bassel; Lesinski, Gregory B. Share Save Monolithic Chip for High-throughput Blood Cell Depletion to Sort Rare Circulating Tumor CellsFachin, Fabio; Spuhler, Philipp; Martel-Foley, Joseph M.; Edd, Jon F.; Barber, Thomas A.; Walsh, John; Karabacak, Murat; Pai, Vincent; Yu, Melissa; Smith, Kyle; Hwang, Henry; Yang, Jennifer; Shah, Sahil; Yarmush, Ruby; Sequist, Lecia V.; Stott, Shannon L.; Maheswaran, Shyamala; Haber, Daniel A.; Kapur, Ravi; Toner, Mehmet Share Save Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family InhibitorPerera, Timothy P. S.; Jovcheva, Eleonora; Mevellec, Laurence; Vialard, Jorge; De lange, Desiree; Verhulst, Tinne; Paulussen, Caroline; Van De Ven, Kelly; King, Peter; Freyne, Eddy; Rees, David C.; Squires, Matthew; Saxty, Gordon; Page, Martin; Murray, Christopher W.; Gilissen, Ron; Ward, George; Thompson, Neil T.; Newell, David R.; Cheng, Na; Xie, Liang; Yang, Jennifer; Platero, Suso J.; Karkera, Jayaprakash D.; Moy, Christopher; Angibaud, Patrick; Laquerre, Sylvie; Lorenzi, Matthew V. Share Save Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single cellsHan, Lin; Wu, Hua-Jun; Zhu, Haiying; Kim, Kun-Yong; Marjani, Sadie L.; Riester, Markus; Euskirchen, Ghia; Zi, Xiaoyuan; Yang, Jennifer; Han, Jasper; Snyder, Michael; Park, In-Hyun; Irizarry, Rafael; Weissman, Sherman M.; Michor, Franziska; Fan, Rong; Pan, Xinghua Share Save Single cell transcriptomics reveals unanticipated features of early hematopoietic precursorsYang, Jennifer; Tanaka, Yoshiaki; Seay, Montrell; Li, Zhen; Jin, Jiaqi; Garmire, Lana Xia; Zhu, Xun; Taylor, Ashley; Li, Weidong; Euskirchen, Ghia; Halene, Stephanie; Kluger, Yuval; Snyder, Michael P.; Park, In-Hyun; Pan, Xinghua; Weissman, Sherman Morton Share Save Selinexor, a selective inhibitor of nuclear export (SINE), enhances the in vivo efficacy of checkpoint blockade with antibodies targeting CTLA4 or PD-1/PD-L1 in melanomaFarren, Matthew R.; Shakya, Reena; Hennessey, Rebecca; Mace, Thomas; Yang, Jennifer; Elnaggar, Omar; Young, Gregory; Landesman, Yosef; Carlson, Robert; Elloul, Sivan; Crochiere, Marsha; Burd, Christin; Lesinski, Gregory B. Share Save Share Save Share Save Combined inhibition of MEK and PI3K elicits anti-tumor activity in human cholangiocarcinomaYang, Jennifer; Elnaggar, Omar; Mace, Thomas; Farren, Matthew; Young, Gregory; Lee, Patrice; Keenan, Kaitlin; Che, Zheng; Kaufman, Jacob; Guttridge, Denis; Carbone, David; Timmers, Cynthia; Bekaii-Saab, Tanios; Lesinski, Gregory Share Save Dual targeting of MEK and PI3K pathways can act via tumor-intrinsic mechanisms to overcome resistance and tumor-extrinsic mechanisms to modulate immunity and limit cancer cachexiaYang, Jennifer; Talbert, Erin; Elnaggar, Omar; Rajasekera, Priyani; Mace, Thomas; Farren, Matthew; Che, Zheng; Swanson, Benjamin; Young, Gregory; Haverick, Ericka; Timmers, Cynthia; Bloomston, Mark; Bekaii-Saab, Tanios; Guttridge, Denis; Lesinski, Gregory Share Save Share Save STAT3 inhibitors elicit direct anti-tumor effects against human biliary caner cell lines and limit release of immune suppressive cytokines in vitroYang, Jennifer; Keenan, Kaitlin; Mace, Thomas; Bekaii-Saab, Tanios; Fuchs, James; Schwartz, Eric; Li, Chenglong; Lin, Jiayuh; Li, Pui-Kai; Lesinski, Gregory Share Save Chemogenetic Evaluation of the Mitotic Kinesin CENP-E Reveals a Critical Role in Triple-Negative Breast CancerKung, Pei-Pei; Martinez, Ricardo; Zhu, Zhou; Zager, Michael; Blasina, Alessandra; Rymer, Isha; Hallin, Jill; Xu, Meirong; Carroll, Christopher; Chionis, John; Wells, Peter; Kozminski, Kirk; Fan, Jeffery; Guicherit, Oivin; Huang, Buwen; Cui, Mei; Liu, Chaoting; Huang, Zhongdong; Sistla, Anand; Yang, Jennifer; Murray, Brion W. Share Save Microfluidic, marker-free isolation of circulating tumor cells from blood samplesKarabacak, Nezihi Murat; Spuhler, Philipp S.; Fachin, Fabio; Lim, Eugene J.; Pai, Vincent; Ozkumur, Emre; Martel, Joseph M.; Kojic, Nikola; Smith, Kyle; Chen, Pin-i; Yang, Jennifer; Hwang, Henry; Morgan, Bailey; Trautwein, Julie; Barber, Thomas A.; Stott, Shannon L.; Maheswaran, Shyamala; Kapur, Ravi; Haber, Daniel A.; Toner, Mehmet Share Save Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cellsQiu, Ming; Peng, Qinghai; Jiang, Ivy; Carroll, Christopher; Han, Guangzhou; Rymer, Isha; Lippincott, John; Zachwieja, Joseph; Gajiwala, Ketan; Kraynov, Eugenia; Thibault, Stephane; Stone, Donna; Gao, Yijie; Sofia, Susan; Gallo, Jorge; Li, Gang; Yang, Jennifer; Li, Kang; Wei, Ping Share Save 
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