Not logged in Using a novel panel of drug-resistant triple-negative breast cancer cell lines to identify candidate therapeutic targets and biomarkers Grimsley, Helen E.; Antczak, Magdalena; Reddin, Ian G.; Weiler, Nicole; Mclaughlin, Katie-May; Rothweiler, Florian; Haas, Johannes; Nist, Andrea; Mernberger, Marco; Stiewe, Thorsten; Fenton, Tim R.; Speidel, Daniel; Harper-Wynne, Catherine; Cox, Karina; Heckl, Dirk; Cinatl, Jindrich; Wass, Mark N.; Garrett, Michelle D.; Michaelis, Martin Share Save
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heredERA Breast Cancer: a phase III, randomized, open-label study evaluating the efficacy and safety of giredestrant plus the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection in patients with previously untreated HER2-positive, estrogen receptor-positive locally advanced or metastatic breast cancer Kuemmel, Sherko; Harper-Wynne, Catherine; Park, Yeon Hee; Franke, Fabio; de Laurentiis, Michelino; Schumacher-Wulf, Eva; Eiger, Daniel; Heeson, Sarah; Cardona, Andres; Ozyilkan, Ozgur; Morales-Vasquez, Flavia; Metcalfe, Ciara; Hafner, Marc; Restuccia, Eleonora; O'Shaughnessy, Joyce Share Save
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Tracking triple negative breast cancer (TNBC) evolution in the molecular residual disease (MRD) setting in the c-TRAK TN clinical trial Coakley, Maria; Cutts, Rosalind J.; Sritharan, Prithika; Hrebien, Sarah; Swift, Claire; Dunne, Kathryn; Kilburn, Lucy; Goddard, Katie; Villacampa, Guillermo; Rojas, Patricia; Emmett, Warren; Pipinikas, Christodoulos; Hall, Peter; Harper-Wynne, Catherine; Hickish, Tamas; Macpherson, Iain; Okines, Alicia; Wardley, Andrew; Wheatley, Duncan; Waters, Simon; Bliss, Judith M.; Garcia-Murillas, Isaac; Turner, Nicholas C. Share Save
A population-scale temporal case-control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP) Starkey, Thomas; Ionescu, Maria; Tilby, Michael; Little, Martin W.; Burke, Emma; Fittall, Matthew; Khan, Sam R.; Liu, Justin K. H.; Platt, James R.; Mew, Rosie; Tripathy, Arvind; Watts, Isabella; Williams, Sophie Therese; Appanna, Nathan; Al-Hajji, Youssra; Barnard, Matthew; Benny, Liza; Burnett, Alexander L.; Bytyci, Jola; Cattell, Emma J.; Cheng, Vinton; Clark, James; Eastlake, Leonie; Gerrand, Kate; Ghafoor, Qamar; Grumett, Simon; Harper-Wynne, Catherine; Kahn, Rachel; Lee, Alvin J. X.; Lomas, Oliver; Lydon, Anna; Mckenzie, Hayley; Kinloch, Emma; Lam, Emily; Murphy, Gillian; Rhodes, Malcolm; Robinson, Kate; Panneerselvam, Hari S.; Pascoe, Jennifer; Patel, Grisma; Patel, Vijay A.; Potter, Vanessa; Randle, Amelia S.; Rigg, Anne M.; Robinson, Tim; Roylance, Rebecca W.; Roques, Tom; Rozmanowski, Stefan; Roux, Rene L.; Shah, Ketan; Sheehan, Remarez; Sintler, Martin; Swarup, Sanskriti; Taylor, Harriet; Tillett, Tania; Tuthill, Mark; Williams, Sarah; Ying, Yuxin; Beggs, Andrew; Iveson, Tim; Lee, Siow Ming; Middleton, Gary; Middleton, Mark; Protheroe, Andrew; Fowler, Tom; Johnson, Peter; Lee, Lennard Y. W.; NCRI Consumer Forum Share Save
A real-world study of the first use of palbociclib for the treatment of advanced breast cancer within the UK National Health Service as part of the novel Ibrance® Patient Program Palmieri, Carlo; Musson, Alison; Harper-Wynne, Catherine; Wheatley, Duncan; Bertelli, Gianfilippo; Macpherson, Iain R.; Nathan, Mark; McDowall, Ellie; Bhojwani, Ajay; Verrill, Mark; Eva, Joe; Doody, Colm; Chowdhury, Ruhe Share Save
Comparison of a personalized sequencing assay and digital PCR for circulating tumor DNA based Molecular Residual Disease detection in early-stage triple negative breast cancer in the cTRAK-TN trial Coakley, Maria; Sritharan, Prithika; Villacampa, Guillermo; Swift, Claire; Dunne, Kathryn; Kilburn, Lucy; Goddard, Katie; Rojas, Patricia; Joad, Andy; Emmett, Warren; Knape, Charlene; Howarth, Karen; Hall, Peter S.; Harper-Wynne, Catherine; Hickish, Tamas; Macpherson, Iain; Okines, Alicia F.; Wardley, Andrew M.; Wheatley, Duncan; Waters, Simon; Cutts, Rosalind; Garcia-Murillas, Isaac; Bliss, Judith; Turner, Nicholas Share Save
heredERA Breast Cancer: Phase III study of first-line, fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection ± giredestrant (GDC-9545) for estrogen receptor+, HER2+advanced breast cancer Kuemmel, Sherko; Harper-Wynne, Catherine; Park, Yeon H.; Franke, Fabio; De laurentiis, Michelino; Schumacher-Wulf, Eva; Eiger, Daniel; Heeson, Sarah; Shivhare, Mahesh; Restuccia, Eleonora; O'Shaughnessy, Joyce Share Save
Results of the c-TRAK TN trial: a clinical trial utilising ctDNA mutation tracking to detect molecular residual disease and trigger intervention in patients with moderate- and high-risk early-stage triple-negative breast cancer Turner, N. C.; Swift, C.; Jenkins, B.; Kilburn, L.; Coakley, M.; Beaney, M.; Fox, L.; Goddard, K.; Garcia-Murillas, I.; Proszek, P.; Hall, P.; Harper-Wynne, C.; Hickish, T.; Kernaghan, S.; Macpherson, I. R.; Okines, A. F. C.; Palmieri, C.; Perry, S.; Randle, K.; Snowdon, C.; Stobart, H.; Wardley, A. M.; Wheatley, D.; Waters, S.; Winter, M. C.; Hubank, M.; Allen, S. D.; Bliss, J. M. Share Save
Safe prescribing in cancer patients during the COVID-19 pandemic: A new initiative from the UK Cancer Coronavirus Project (UKCCP) team Appanna, Nathan; Patel, Grisma; Burke, Emma; Burnett, Alexander; Clark, James; Mew, Rosie; Khan, Sam; Little, Martin; Liu, Justin; Panneerselvam, Hari; Patel, Vijay; Platt, James; Tilby, Michael; Watts, Isabella; Harper-Wynne, Catherine; Lee, Lennard Y. W. Share Save
COVID-19: Third dose booster vaccine effectiveness against breakthrough coronavirus infection, hospitalisations and death in patients with cancer: A population-based study Lee, Lennard Y. W.; Ionescu, Maria C.; Starkey, Thomas; Little, Martin; Tilby, Michael; Tripathy, Arvind R.; Mckenzie, Hayley S.; Al-Hajji, Youssra; Appanna, Nathan; Barnard, Matthew; Benny, Liza; Burnett, Alexander; Cattell, Emma L.; Clark, James J.; Khan, Sam; Ghafoor, Qamar; Panneerselvam, Hari; Illsley, George; Harper-Wynne, Catherine; Hattersley, Rosie J.; Lee, Alvin J. X.; Lomas, Oliver; Liu, Justin K. H.; McCauley, Amanda; Pang, Matthew; Pascoe, Jennifer S.; Platt, James R.; Patel, Grisma; Patel, Vijay; Potter, Vanessa A.; Randle, Amelia; Rigg, Anne S.; Robinson, Tim M.; Roques, Tom W.; Roux, Rene L.; Rozmanowski, Stefan; Taylor, Harriet; Tuthill, Mark H.; Watts, Isabella; Williams, Sarah; Beggs, Andrew; Iveson, Tim; Lee, Siow M.; Middleton, Gary; Middleton, Mark; Protheroe, Andrew; Fittall, Matthew W.; Fowler, Tom; Johnson, Peter Share Save
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Primary results of the cTRAK TN trial: A clinical trial utilising ctDNA mutation tracking to detect minimal residual disease and trigger intervention in patients with moderate and high risk early stage triple negative breast cancer Turner, Nicholas; Swift, Claire; Jenkins, Ben; Kilburn, Lucy; Coakley, Maria; Beaney, Matthew; Fox, Lisa; Goddard, Katie; Garcia-Murillas, Isaac; Hall, Peter; Harper-Wynne, Catherine; Hickish, Tamas; Kernaghan, Sarah; Macpherson, Iain; Okines, Alicia; Palmieri, Carlo; Perry, Sophie; Randle, Katrina; Snowdon, Claire; Stobart, Hilary; Wardley, Andrew; Wheatley, Duncan; Waters, Simon; Winter, Matthew; Bliss, Judith Share Save
Palbociclib in combination with aromatase inhibitors in patients ≥ 75 years with oestrogen receptor-positive, human epidermal growth factor receptor 2 negative advanced breast cancer: A real-world multicentre UK study El Badri, Salma; Tahir, Bilal; Balachandran, Kirsty; Bezecny, Pavel; Britton, Fiona; Davies, Mark; Desouza, Karen; Dixon, Simon; Hills, Daniel; Moe, Maung; Pigott, Thomas; Proctor, Andrew; Shah, Yatri; Simcock, Richard; Stansfeld, Anna; Synowiec, Alicja; Theodoulou, Marianna; Verrill, Mark; Wadhawan, Anshu; Harper-Wynne, Catherine; Wilson, Caroline Share Save
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A real-world data analysis: The first United Kingdom experience of cyclin-dependent kinase 4/6 inhibitor in advanced breast cancer in the National Health Service within an access program Palmieri, C.; Musson, A.; Harper-Wynne, C.; Wheatley, D.; Bertelli, G.; MacPherson, I.; Nathan, M.; Verrill, M.; Eva, J.; Doody, C.; Chowdhury, R. Share Save
Palbociclib combined with aromatase inhibitors (AIs) in women ≥75 years with oestrogen receptor positive (ER plus ve), human epidermal growth factor receptor 2 negative (HER2-ve) advanced breast cancer: A real-world multicentre UK study El Badri, S.; Tahir, B.; Balachandran, K.; Bezecny, P.; Britton, F.; DeSouza, K.; Hills, D.; Moe, M.; Pigott, T.; Proctor, A.; Shah, Y.; Simcock, R.; Stansfeld, A.; Synowiec, A.; Theodoulou, M.; Verrill, M.; Wadhawan, A.; Harper-Wynne, C.; Wilson, C. Share Save
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