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The OASIS Consortium: integrating multi-omics technologies to transform chemical safety assessment Rouquie, David; Bender, Andreas; Cheah, Jaime; Crute, Christine E.; Dalmas, Deidre; Ewald, Jessica; Fullerton, Aaron; Harrill, Joshua A.; Kadri, Sabah; Kleinstreuer, Nicole; Kramer, Nynke; LaRocca, Jessica; Mitchell, Constance A.; Seal, Srijit; Singh, Shantanu; Carpenter, Anne E. Share Save
Scalable, compressed phenotypic screening using pooled perturbations Liu, Nuo; Kattan, Walaa E.; Mead, Benjamin E.; Kummerlowe, Conner; Cheng, Thomas; Ingabire, Sarah; Cheah, Jaime H.; Soule, Christian K.; Vrcic, Anita; Mcininch, Jane K.; Triana, Sergio; Guzman, Manuel; Dao, Tyler T.; Peters, Joshua M.; Lowder, Kristen E.; Crawford, Lorin; Amini, Ava P.; Blainey, Paul C.; Hahn, William C.; Cleary, Brian; Bryson, Bryan; Winter, Peter S.; Raghavan, Srivatsan; Shalek, Alex K. Share Save
Drinkable in situ-forming tough hydrogels for gastrointestinal therapeutics Liu, Gary W.; Pickett, Matthew J.; Kuosmanen, Johannes L. P.; Ishida, Keiko; Madani, Wiam A. M.; White, Georgia N.; Jenkins, Joshua; Park, Sanghyun; Feig, Vivian R.; Jimenez, Miguel; Karavasili, Christina; Lal, Nikhil B.; Murphy, Matt; Lopes, Aaron; Morimoto, Joshua; Fitzgerald, Nina; Cheah, Jaime H.; Soule, Christian K.; Fabian, Niora; Hayward, Alison; Langer, Robert; Traverso, Giovanni Share Save
Screening in serum-derived medium reveals differential response to compounds targeting metabolism Abbott, Keene L.; Ali, Ahmed; Casalena, Dominick; Do, Brian T.; Ferreira, Raphael; Cheah, Jaime H.; Soule, Christian K.; Deik, Amy; Kunchok, Tenzin; Schmidt, Daniel R.; Renner, Steffen; Honeder, Sophie E.; Wu, Michelle; Chan, Sze Ham; Tseyang, Tenzin; Stoltzfus, Andrew T.; Michel, Sarah L. J.; Greaves, Daniel; Hsu, Peggy P.; Ng, Christopher W.; Zhang, Chelsea J.; Farsidjani, Ali; Kent, Johnathan R.; Madariaga, Maria Lucia L.; Gramatikov, Iva Monique T.; Matheson, Nicholas J.; Lewis, Caroline A.; Clish, Clary B.; Rees, Matthew G.; Roth, Jennifer A.; Griner, Lesley Mathews; Muir, Alexander; Auld, Douglas S.; Heiden, Matthew G. Vander Share Save
Drug repurposing and genetic screening strategies for effective treatment discovery in soft-tissue sarcomas Al-Jazrawe, Mushriq; Cebula, Kathryn; Abeyta, Elisabeth A.; Curtis, Haley S.; McIninch, Jane K.; Cheah, Jaime H.; Berstler, James; Miller, Lisa; Neiswender, James; Brenan, Lisa; Burger, Mike; Vazquez, Francisca; Boehm, Jesse S. Share Save
Functional roles of enhancers in immune microenvironment & immunotherapy response Rai, Kunal; Maitituoheti, Mayinuer; Shi, Alvin; Tang, Ming; Ho, Li-Lun; Kreidieh, Firas Youssef; Terranova, Christopher; Galani, Kyriakitsa; Keung, Emily Z.; Creasy, Caitlin A.; Wu, Manrong; Chen, Jiajia; Chen, Nana; Singh, Anand K.; Chaudhri, Apoorvi; Anvar, Nazanin E.; Tarrantino, Giuseppe; Yang, Jiekun; Sarkar, Sharmistha; Jiang, Shan; Malke, Jared; Haydu, Lauren; Burton, Elizabeth; Davies, Michael A.; Gershenwald, Jeffrey E.; Hwu, Patrick; Lazar, Alexander; Cheah, Jaime H.; Soule, Christian K.; Levine, Stuart S.; Bernatchez, Chantale; Saladi, Srinivas V.; Liu, David; Tawbi, Hussein; Wargo, Jennifer; Boland, Genevieve M.; Kellis, Manolis Share Save
Computationally guided high-throughput design of self-assembling drug nanoparticles Reker, Daniel; Rybakova, Yulia; Kirtane, Ameya R.; Cao, Ruonan; Yang, Jee Won; Navamajiti, Natsuda; Gardner, Apolonia; Zhang, Rosanna M.; Esfandiary, Tina; L'Heureux, Johanna; von Erlach, Thomas; Smekalova, Elena M.; Leboeuf, Dominique; Hess, Kaitlyn; Lopes, Aaron; Rogner, Jaimie; Collins, Joy; Tamang, Siddartha M.; Ishida, Keiko; Chamberlain, Paul; Yun, DongSoo; Lytton-Jean, Abigail; Soule, Christian K.; Cheah, Jaime H.; Hayward, Alison M.; Langer, Robert; Traverso, Giovanni Share Save
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Identification and local delivery of vasodilators for the reduction of ureteral contractions Lee, Christopher X.; Cheah, Jaime H.; Soule, Christian K.; Ding, Huiming; Whittaker, Charles A.; Karhohs, Kyle; Burds, Aurora A.; Subramanyam, Kriti S.; Carpenter, Anne E.; Eisner, Brian H.; Cima, Michael J. Share Save
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Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors Oberlick, Elaine M.; Rees, Matthew G.; Seashore-Ludlow, Brinton; Vazquez, Francisca; Nelson, Geoffrey M.; Dharia, Neekesh V.; Weir, Barbara A.; Tsherniak, Aviad; Ghandi, Mahmoud; Krill-Burger, John M.; Meyers, Robin M.; Wang, Xiaofeng; Montgomery, Phil; Root, David E.; Bieber, Jake M.; Radko, Sandi; Cheah, Jaime H.; Hon, C. Suk-Yee; Shamji, Alykhan F.; Clemons, Paul A.; Park, Peter J.; Dyer, Michael A.; Golub, Todd R.; Stegmaier, Kimberly; Hahn, William C.; Stewart, Elizabeth A.; Schreiber, Stuart L.; Roberts, Charles W. M. Share Save
Comprehensive molecular characterization and high-throughput chemical screening identifies genetic dependencies and molecular vulnerabilities in glioblastoma cell line models Ferrer-Luna, Ruben; Ramkissoon, Shakti H.; Ramkissoon, Lori A.; Pellton, Kristine; Schumacher, Steven E.; Lamothe, Rebecca; Cheah, Jaime H.; Haidar, Sam; Kang, Yun J.; Knoff, David S.; Maire, Cecile L.; Olausson, Karl H.; Song, Wenyu; Idbaih, Ahmed; Rinne, Mikael L.; Reardon, David A.; Wen, Patrick Y.; Clemons, Paul A.; Schreiber, Stuart L.; Shamji, Alykhan J.; Beroukhim, Rameen; Ligon, Keith L. Share Save
Pharmacogenomic interactions in glioblastoma cell line models Ferrer-Luna, Ruben; Ramkissoon, Shakti H.; Olausson, Karl H.; Ramkissoon, Lori A.; Schumacher, Steven; Lamothe, Rebecca; Cheah, Jaime H.; Pellton, Kristine; Haidar, Sam; Kang, Yun J.; Paolella, Brenton R.; Maire, Cecile; Song, Wenyu; Meng, Alice; Idbaih, Ahmed; Rinne, Mikael L.; Reardon, David A.; Wen, Patrick Y.; Clemons, Paul A.; Schreiber, Stuart L.; Shamji, Alykhan F.; Beroukhim, Rameen; Ligon, Keith L. Share Save
Accelerating prediction of pediatric and rare cancer vulnerabilities using next-generation cancer models Tseng, Yuen-Yi; Hong, Andrew; Keskula, Paula; Gill, Shubhroz; Cheah, Jaime; Kryukov, Grigoriy; Tsherniak, Aviad; Vazquez, Francisca; Cowley, Glenn; Alkhairy, Sahar; Oh, Coyin; Peng, Anson; Deasy, Rebecca; Sayeed, Abeer; Ronning, Peter; Ng, Samuel; Corsello, Steven; Painter, Corrie; Sandak, David; Garraway, Levi; Rubin, Mark; Kuo, Calvin; Puram, Sidharth; Weinstock, David; Bass, Adam; Wagle, Nikhil; Ligon, Keith; Janeway, Katherine; Root, David; Schreiber, Stuart; Clemons, Paul; Shamji, Aly; Shamji, Aly; Hahn, William; Golub, Todd; Boehm, Jesse Share Save
Accelerating prediction of tumor vulnerabilities using next-generation cancer models Tseng, Yuen-Yi; Hong, Andrew; Keskula, Paula; Gill, Shubhroz; Cheah, Jaime; Kryukov, Grigoriy; Tsherniak, Aviad; Vazquez, Francisca; Cowley, Glenn; Oh, Coyin; Peng, Anson; Sayeed, Abeer; Deasy, Rebecca; Ronning, Peter; Kantoff, Philip; Garraway, Levi; Rubin, Mark; Kuo, Calvin; Puram, Sidharth; Gazdar, Adi; Dela Cruz, Filemon; Bass, Adam; Wagle, Nikhil; Ligon, Keith; Janeway, Katherine; Root, David; Schreiber, Stuart; Clemons, Paul; Shamji, Aly; Hahn, William; Golub, Todd; Boehm, Jesse S. Share Save
Integrated genetic and pharmacologic interrogation of rare cancers Hong, Andrew L.; Tseng, Yuen-Yi; Cowley, Glenn S.; Jonas, Oliver; Cheah, Jaime H.; Kynnap, Bryan D.; Doshi, Mihir B.; Oh, Coyin; Meyer, Stephanie C.; Church, Alanna J.; Gill, Shubhroz; Bielski, Craig M.; Keskula, Paula; Imamovic, Alma; Howell, Sara; Kryukov, Gregory V.; Clemons, Paul A.; Tsherniak, Aviad; Vazquez, Francisca; Crompton, Brian D.; Shamji, Alykhan F.; Rodriguez-Galindo, Carlos; Janeway, Katherine A.; Roberts, Charles W. M.; Stegmaier, Kimberly; van Hummelen, Paul; Cima, Michael J.; Langer, Robert S.; Garraway, Levi A.; Schreiber, Stuart L.; Root, David E.; Hahn, William C.; Boehm, Jesse S. Share Save
Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects Wagner, Florence F.; Bishop, Joshua A.; Gale, Jennifer P.; Shi, Xi; Walk, Michelle; Ketterman, Joshua; Patnaik, Debasis; Barker, Doug; Walpita, Deepika; Campbell, Arthur J.; Nguyen, Shannon; Lewis, Michael; Ross, Linda; Weiwer, Michel; An, W. Frank; Germain, Andrew R.; Nag, Partha P.; Metkar, Shailesh; Kaya, Taner; Dandapani, Sivaraman; Olson, David E.; Barbe, Anne-Laure; Lazzaro, Fanny; Sacher, Joshua R.; Cheah, Jaime H.; Fei, David; Perez, Jose; Munoz, Benito; Palmer, Michelle; Stegmaier, Kimberly; Schreiber, Stuart L.; Scolnick, Edward; Zhang, Yan-Ling; Haggarty, Stephen J.; Holson, Edward B.; Pan, Jen Q. Share Save
A genetic basis for the variation in the vulnerability of cancer to DNA damage Yard, Brian D.; Adams, Drew J.; Chie, Eui Kyu; Tamayo, Pablo; Battaglia, Jessica S.; Gopal, Priyanka; Rogacki, Kevin; Pearson, Bradley E.; Phillips, James; Raymond, Daniel P.; Pennell, Nathan A.; Almeida, Francisco; Cheah, Jaime H.; Clemons, Paul A.; Shamji, Alykhan; Peacock, Craig D.; Schreiber, Stuart L.; Hammerman, Peter S.; Abazeed, Mohamed E. Share Save
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