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Peter M. Colman

walter & eliza hall institute

65H-index
195Paper Count
2.2WCitation Count
Published Papers 56
Publication Date
Sequence differences between BAX and BAK core domains manifest as differences in their interactions with lipids
err2024-01-19
err4
PREAI
errMiller, Michelle S.; Cowan, Angus D.; Brouwer, Jason M.; Smyth, Sean T.; Peng, Liuyu; Wardak, Ahmad Z.; Uren, Rachel T.; Luo, Cindy; Roy, Michael J.; Shah, Sayali; Tan, Ziwen; Reid, Gavin E.; Colman, Peter M.; Czabotar, Peter E.
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An increase in mitochondrial TOM activates apoptosis to drive retinal neurodegeneration
err2022-12-14
err6
errOAAI
errPeriasamy, Agalya; Mitchell, Naomi; Zaytseva, Olga; Chahal, Arjun S.; Zhao, Jiamin; Colman, Peter M.; Quinn, Leonie M.; Gulbis, Jacqueline M.
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Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation
err2022-03-12
err6
errOAAI
errRobin, Adeline Y.; Miller, Michelle S.; Iyer, Sweta; Shi, Melissa X.; Wardak, Ahmad Z.; Lio, Daisy; Smith, Nicholas A.; Smith, Brian J.; Birkinshaw, Richard W.; Czabotar, Peter E.; Kluck, Ruth M.; Colman, Peter M.
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The Bak core dimer focuses triacylglycerides in the membrane
err2022-02-01
err2
errOAAI
errSmith, Nicholas A.; Wardak, Ahmad Z.; Cowan, Angus D.; Colman, Peter M.; Czabotar, Peter E.; Smith, Brian J.
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Ion currents through Kir potassium channels are gated by anionic lipids
err2022-01-25
err14
errOAAI
errJin, Ruitao; He, Sitong; Black, Katrina A.; Clarke, Oliver B.; Wu, Di; Bolla, Jani R.; Johnson, Paul; Periasamy, Agalya; Wardak, Ahmad; Czabotar, Peter; Colman, Peter M.; Robinson, Carol, V; Laver, Derek; Smith, Brian J.; Gulbis, Jacqueline M.
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Structure of detergent-activated BAK dimers derived from the inert monomer
err2021-05-01
err30
errOAAI
errBirkinshaw, Richard W.; Iyer, Sweta; Lio, Daisy; Luo, Cindy S.; Brouwer, Jason M.; Miller, Michelle S.; Robin, Adeline Y.; Uren, Rachel T.; Dewson, Grant; Kluck, Ruth M.; Colman, Peter M.; Czabotar, Peter E.
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Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-XL and BCL-2
err2021-04-27
err8
PREAI
errRoy, Michael J.; Vom, Amelia; Okamoto, Toru; Smith, Brian J.; Birkinshaw, Richard W.; Yang, Hong; Abdo, Houda; White, Christine A.; Segal, David; Huang, David C. S.; Baell, Jonathan B.; Colman, Peter M.; Czabotar, Peter E.; Lessene, Guillaume
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Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2
err2021-02-01
err4
PREAI
errNguyen, William; Lee, Erinna F.; Evangelista, Marco; Lee, Mihwa; Harris, Tiffany J.; Colman, Peter M.; Smith, Nicholas A.; Williams, Luke B.; Jarman, Kate E.; Lowes, Kym N.; Haeberli, Cecile; Keiser, Jennifer; Smith, Brian J.; Fairlie, W. Douglas; Sleebs, Brad E.
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BAK core dimers bind lipids and can be bridged by them
err2020-09-14
err50
PREAI
errCowan, Angus D.; Smith, Nicholas A.; Sandow, Jarrod J.; Kapp, Eugene A.; Rustam, Yepy H.; Murphy, James M.; Brouwer, Jason M.; Bernardini, Jonathan P.; Roy, Michael J.; Wardak, Ahmad Z.; Tan, Iris K.; Webb, Andrew I.; Gulbis, Jacqueline M.; Smith, Brian J.; Reid, Gavin E.; Dewson, Grant; Colman, Peter M.; Czabotar, Peter E.
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EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins
err2019-10-23
err44
errOAAI
errFitzsimmons, Leah; Cartlidge, Rachel; Chang, Catherine; Sejic, Nenad; Galbraith, Laura C. A.; Suraweera, Chathura D.; Croom-Carter, Deborah; Dewson, Grant; Tierney, Rosemary J.; Bell, Andrew, I; Shannon-Lowe, Clare; Herold, Marco J.; Rickinson, Alan B.; Colman, Peter M.; Huang, David C. S.; Strasser, Andreas; Kvansakul, Marc; Rowe, Martin; Kelly, Gemma L.
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A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis
err2019-10-07
err29
PREAI
errvan Delft, Mark F.; Chappaz, Stephane; Khakham, Yelena; Chinh T Bui; Debrincat, Marlyse A.; Lowes, Kym N.; Brouwer, Jason M.; Grohmann, Christoph; Sharp, Phillip P.; Dagley, Laura F.; Li, Lucy; McArthur, Kate; Luo, Meng-Xiao; Chin, Hui San; Fairlie, W. Douglas; Lee, Erinna F.; Segal, David; Duflocq, Stephane; Lessene, Romina; Bernard, Sabrina; Peilleron, Laure; Thao Nguyen; Miles, Caroline; Wan, Soo San; Lane, Rachael M.; Wardak, Ahmad; Lackovic, Kurt; Colman, Peter M.; Sandow, Jarrod J.; Webb, Andrew, I; Czabotar, Peter E.; Dewson, Grant; Watson, Keith G.; Huang, David C. S.; Lessene, Guillaume; Kile, Benjamin T.
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Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations
err2019-06-03
err165
errOAAI
errBirkinshaw, Richard W.; Gong, Jia-nan; Luo, Cindy S.; Lio, Daisy; White, Christine A.; Anderson, Mary Ann; Blombery, Piers; Lessene, Guillaume; Majewski, Ian J.; Thijssen, Rachel; Roberts, Andrew W.; Huang, David C. S.; Colman, Peter M.; Czabotar, Peter E.
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Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design
err2017-11-01
err57
errOAAI
errBrouwer, Jason M.; Lan, Ping; Cowan, Angus D.; Bernardini, Jonathan P.; Birkinshaw, Richard W.; van Delft, Mark F.; Sleebs, Brad E.; Robin, Adeline Y.; Wardak, Ahmad; Tan, Iris K.; Reljic, Boris; Lee, Erinna F.; Fairlie, W. Douglas; Call, Melissa J.; Smith, Brian J.; Dewson, Grant; Lessene, Guillaume; Colman, Peter M.; Czabotar, Peter E.
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Vale Colin Ward-A Leader in Receptor Structural Biology
err2017-05-11
err0
errOAAI
errLawrence, Michael C.; Colman, Peter M.
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Targeting BCL-2-like Proteins to Kill Cancer Cells
err2016-08-01
err122
PREAI
errCory, Suzanne; Roberts, Andrew W.; Colman, Peter M.; Adams, Jerry M.
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Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction
err2015-07-09
err61
errOAAI
errRobin, A. Y.; Kumar, K. Krishna; Westphal, D.; Wardak, A. Z.; Thompson, G. V.; Dewson, G.; Colman, P. M.; Czabotar, P. E.
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Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim
err2015-03-12
err37
errOAAI
errMarshall, B.; Puthalakath, H.; Caria, S.; Chugh, S.; Doerflinger, M.; Colman, P. M.; Kvansakul, M.
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The Functional Differences between Pro-survival and Pro-apoptotic B Cell Lymphoma 2 (Bcl-2) Proteins Depend on Structural Differences in Their Bcl-2 Homology 3 (BH3) Domains
err2014-12-01
err39
errOAAI
errLee, Erinna F.; Dewson, Grant; Evangelista, Marco; Pettikiriarachchi, Anne; Gold, Grace J.; Zhu, Haoran; Colman, Peter M.; Fairlie, W. Douglas
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Discovery of a Potent and Selective BCL-XL Inhibitor with in Vivo Activity
err2014-09-08
err286
errOAAI
errTao, Zhi-Fu; Hasvold, Lisa; Wang, Le; Wang, Xilu; Petros, Andrew M.; Park, Chang H.; Boghaert, Erwin R.; Catron, Nathaniel D.; Chen, Jun; Colman, Peter M.; Czabotar, Peter E.; Deshayes, Kurt; Fairbrother, Wayne J.; Flygare, John A.; Hymowitz, Sarah G.; Jin, Sha; Judge, Russell A.; Koehler, Michael F. T.; Kovar, Peter J.; Lessene, Guillaume; Mitten, Michael J.; Ndubaku, Chudi O.; Nimmer, Paul; Purkey, Hans E.; Oleksijew, Anatol; Phillips, Darren C.; Sleebs, Brad E.; Smith, Brian J.; Smith, Morey L.; Tahir, Stephen K.; Watson, Keith G.; Xiao, Yu; Xue, John; Zhang, Haichao; Zobel, Kerry; Rosenberg, Saul H.; Tse, Chris; Leverson, Joel D.; Elmore, Steven W.; Souers, Andrew J.
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Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers
err2014-09-01
err146
errOAAI
errBrouwer, Jason M.; Westphal, Dana; Dewson, Grant; Robin, Adeline Y.; Uren, Rachel T.; Bartolo, Ray; Thompson, Geoff V.; Colman, Peter M.; Kluck, Ruth M.; Czabotar, Peter E.
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