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LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers Li, Chendi; Syed, Mohammed Usman; Nimbalkar, Anahita; Shen, Yi; Vieira, Melissa D.; Fraser, Cameron; Inde, Zintis; Qin, Xingping; Ouyang, Jian; Kreuzer, Johannes; Clark, Sarah E.; Kelley, Grace; Hensley, Emily M.; Morris, Robert; Lazaro, Raul; Belmonte, Brian; Oh, Audris; Walcott, Makeba; Nabel, Christopher S.; Caenepeel, Sean; Saiki, Anne Y.; Rex, Karen; Lipford, J. Russell; Heist, Rebecca S.; Lin, Jessica J.; Haas, Wilhelm; Sarosiek, Kristopher; Hughes, Paul E.; Hata, Aaron N. Share Save
FGFR inhibition blocks NF-ĸB-dependent glucose metabolism and confers metabolic vulnerabilities in cholangiocarcinoma Zhen, Yuanli; Liu, Kai; Shi, Lei; Shah, Simran; Xu, Qin; Ellis, Haley; Balasooriya, Eranga R.; Kreuzer, Johannes; Morris, Robert; Baldwin, Albert S.; Juric, Dejan; Haas, Wilhelm; Bardeesy, Nabeel Share Save
APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease Jackson, Rosemary J.; Keiser, Megan S.; Meltzer, Jonah C.; Fykstra, Dustin P.; Dierksmeier, Steven E.; Hajizadeh, Soroush; Kreuzer, Johannes; Morris, Robert; Melloni, Alexandra; Nakajima, Tsuneo; Tecedor, Luis; Ranum, Paul T.; Carrell, Ellie; Chen, Yonghong; Nishtar, Maryam A.; Holtzman, David M.; Haas, Wilhelm; Davidson, Beverly L.; Hyman, Bradley T. Share Save
Multiomics analysis unravels tumor metabolic reprogramming and potential resistance mechanism(s) to curative therapy in TNBC Ren, Zuen; Kurmi, Kiran; Morris, Robert; Joshi, Shakchhi; Zaniewski, Eric; Kreuzer, Johannes; Gioia, Gabrielle Elena; Bossuyt, Veerle I.; Dontchos, Brian N.; Wang, Gary X.; Chou, Shinn-Huey S.; Spring, Laura M.; Haas, Wilhelm; Haigis, Marcia C.; Ellisen, Leif W. Share Save
Genetic retargeting of E3 ligases to enhance CAR T cell therapy Lane, Isabel C.; Kembuan, Gabriele; Carreiro, Jeannie; Kann, Michael C.; Lin, William; Bouffard, Amanda A.; Kreuzer, Johannes; Morris, Robert; Schneider, Emily M.; Kim, Joanna Y.; Zou, Charles; Salas-Benito, Diego; Gasser, Jessica A.; Leick, Mark B.; Slabicki, Mikolaj; Haas, Wilhelm; V. Maus, Marcela; Jan, Max Share Save
Immunological modifications following chemotherapy are associated with delayed recurrence of ovarian cancer Adzibolosu, Nicholas; Alvero, Ayesha B.; Ali-Fehmi, Rouba; Gogoi, Radhika; Corey, Logan; Tedja, Roslyn; Chehade, Hussein; Gogoi, Vir; Morris, Robert; Anderson, Matthew; Vitko, Julie; Lam, Clarissa; Craig, Douglas B.; Draghici, Sorin; Rutherford, Thomas; Mor, Gil Share Save
Multiomics analysis of triple negative breast cancer identifies potential metabolic vulnerability for overcoming the resistance of neoadjuvant therapy Ren, Zuen; Kurmi, Kiran; Morris, Robert; Joshi, Shakchhi; Zaniewski, Eric; Kreuzer, Johannes; Gioia, Gabrielle Elena; Haas, Wilhelm; Haigis, Marcia C.; Ellisen, Leif W. Share Save
TGF β in the microenvironment induces a physiologically occurring immune-suppressive senescent state Matsuda, Satoru; Revandkar, Ajinkya; Dubash, Taronish D.; Ravi, Arvind; Wittner, Ben S.; Lin, Maoxuan; Morris, Robert; Burr, Risa; Guo, Hongshan; Seeger, Karsen; Szabolcs, Annamaria; Che, Dante; Nieman, Linda; Getz, Gad A.; Ting, David T.; Lawrence, Michael S.; Gainor, Justin; Haber, Daniel A.; Maheswaran, Shyamala Share Save
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Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression Sanidas, Ioannis; Lee, Hanjun; Rumde, Purva H.; Boulay, Gaylor; Morris, Robert; Golczer, Gabriel; Boulay, Hanjun Gaylor; Stanzione, Marcelo; Hajizadeh, Soroush; Zhong, Jun; Ryan, Meagan B.; Corcoran, Ryan B.; Drapkin, Benjamin J.; Rivera, Miguel N.; Dyson, Nicholas J.; Lawrence, Michael S. Share Save
Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment Wallace-Povirk, Adrianne; Rubinsak, Lisa; Malysa, Agnes; Dzinic, Sijana H.; Ravindra, Manasa; Schneider, Mathew; Glassbrook, James; O'Connor, Carrie; Hou, Zhanjun; Kim, Seongho; Back, Jessica; Polin, Lisa; Morris, Robert T.; Gangjee, Aleem; Gibson, Heather; Matherly, Larry H. Share Save
Ovarian cancer modulates the immunosuppressive function of CD11b+Gr1+ myeloid cells via glutamine metabolism Udumula, Mary P.; Sakr, Sharif; Dar, Sajad; Alvero, Ayesha B.; Ali-Fehmi, Rouba; Abdulfatah, Eman; Li, Jing; Jiang, Jun; Tang, Amy; Buekers, Thomas; Morris, Robert; Munkarah, Adnan; Giri, Shailendra; Rattan, Ramandeep Share Save
Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses (vol 4, 977, 2021) Rajasekaran, Swetha; Siddiqui, Jalal; Rakijas, Jessica; Nicolay, Brandon; Lin, Chenyu; Khan, Eshan; Patel, Rahi; Morris, Robert; Wyler, Emanuel; Boukhali, Myriam; Balasubramanyam, Jayashree; Ranjith Kumar, R.; Van Rechem, Capucine; Vogel, Christine; Elchuri, Sailaja V.; Landthaler, Markus; Obermayer, Benedikt; Haas, Wilhelm; Dyson, Nicholas; Miles, Wayne Share Save
Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics Carlyle, Becky C.; Kandigian, Savannah E.; Kreuzer, Johannes; Das, Sudeshna; Trombetta, Bianca A.; Kuo, Yikai; Bennett, David A.; Schneider, Julie A.; Petyuk, Vladislav A.; Kitchen, Robert R.; Morris, Robert; Nairn, Angus C.; Hyman, Bradley T.; Haas, Wilhelm; Arnold, Steven E. Share Save
Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses Rajasekaran, Swetha; Siddiqui, Jalal; Rakijas, Jessica; Nicolay, Brandon; Lin, Chenyu; Khan, Eshan; Patel, Rahi; Morris, Robert; Wyler, Emanuel; Boukhali, Myriam; Balasubramanyam, Jayashree; Ranjith Kumar, R.; Van Rechem, Capucine; Vogel, Christine; Elchuri, Sailaja V.; Landthaler, Markus; Obermayer, Benedikt; Haas, Wilhelm; Dyson, Nicholas; Miles, Wayne Share Save
Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier Yonker, Lael M.; Gilboa, Tal; Ogata, Alana F.; Senussi, Yasmeen; Lazarovits, Roey; Boribong, Brittany P.; Bartsch, Yannic C.; Loiselle, Maggie; Noval Rivas, Magali; Porritt, Rebecca A.; Lima, Rosiane; Davis, Jameson P.; Farkas, Eva J.; Burns, Madeleine D.; Young, Nicola; Mahajan, Vinay S.; Hajizadeh, Soroush; Lopez, Xcanda I. Herrera; Kreuzer, Johannes; Morris, Robert; Martinez, Enid E.; Han, Isaac; Griswold, Kettner, Jr.; Barry, Nicholas C.; Thompson, David B.; Church, George; Edlow, Andrea G.; Haas, Wilhelm; Pillai, Shiv; Arditi, Moshe; Alter, Galit; Walt, David R.; Fasano, Alessio Share Save
E2F/Dp inactivation in fat body cells triggers systemic metabolic changes Zappia, Maria Paula; Guarner, Ana; Kellie-Smith, Nadia; Rogers, Alice; Morris, Robert; Nicolay, Brandon; Boukhali, Myriam; Haas, Wilhelm; Dyson, Nicholas J.; Frolov, Maxim, V Share Save
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