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Highly potent quinoxalinediones inhibit a-hemolysin and ameliorate Staphylococcus aureus lung infections Shekhar, Aditya; Di Lucrezia, Raffaella; Jerye, Karoline; Korotkov, Vadim S.; Harmrolfs, Kirsten; Rox, Katharina; Weich, Herbert A.; Ghai, Ishan; Delhommel, Florent; Becher, Isabelle; Degenhart, Carsten; Fansa, Eyad; Unger, Anke; Habenberger, Peter; Klebl, Bert; Lukat, Peer; Schmelz, Stefan; Henke, Steffi; Borgert, Sebastian; Lang, Julia C.; Sasse, Florenz; Diestel, Randi; Richter, Clementine; Schneider-Daum, Nicole; Hinkelmann, Bettina; Niemz, Jana; Lehr, Claus-Michael; Jaensch, Lothar; Huehn, Jochen; Alm, Richard; Savitski, Mikhail; Welte, Tobias; Hesterkamp, Thomas; Sattler, Michael; Winterhalter, Mathias; Blankenfeldt, Wulf; Medina, Eva; Bilitewski, Ursula; Dinkel, Klaus; Broenstrup, Mark Share Save
P2X7R antagonism suppresses long-lasting brain hyperexcitability following traumatic brain injury in mice Alves, Mariana; de Diego-Garcia, Laura; Vegliante, Gloria; Moreno, Oscar; Gil, Beatriz; Ramos-Cabrer, Pedro; Mitra, Meghma; Martin, Ana Fernandez; Menendez-Mendez, Aida; Wang, Yitao; Strogulski, Nathan Ryzewski; Sun, Meng-Juan; Melia, Ciara; Conte, Giorgia; Plaza-Garcia, Sandra; Khalin, Igor; Teng, Xinchen; Plesnila, Nikolaus; Klebl, Bert; Dinkel, Klaus; Hamacher, Michael; Bhattachary, Anindya; Ceusters, Marc; Palmer, James; Loane, David J.; Llop, Jordi; Henshall, David C.; Engel, Tobias Share Save
TRPC5 controls the adrenaline-mediated counter regulation of hypoglycemia Broeker-Lai, Jenny; Terol, Jose Rego; Richter, Christin; Mathar, Ilka; Wirth, Angela; Kopf, Stefan; Moreno-Perez, Ana; Buettner, Michael; Tan, Linette Liqi; Makke, Mazen; Poschet, Gernot; Hermann, Julia; Tsvilovskyy, Volodymyr; Haberkorn, Uwe; Wartenberg, Philipp; Susperreguy, Sebastian; Berlin, Michael; Ottenheijm, Roger; Philippaert, Koenraad; Wu, Moya; Wiedemann, Tobias; Herzig, Stephan; Belkacemi, Anouar; Levinson, Rebecca T.; Agarwal, Nitin; Londono, Juan E. Camacho; Klebl, Bert; Dinkel, Klaus; Zufall, Frank; Nussbaumer, Peter; Boehm, Ulrich; Hell, Ruediger; Nawroth, Peter; Birnbaumer, Lutz; Leinders-Zufall, Trese; Kuner, Rohini; Zorn, Markus; Bruns, Dieter; Schwarz, Yvonne; Freichel, Marc Share Save
Pyrrolopyrimidine based CSF1R inhibitors: Attempted departure from Flatland Bjornstad, Frithjof; Havik, Simen; Aarhus, Thomas Ihle; Mahdi, Iktedar; Unger, Anke; Habenberger, Peter; Degenhart, Carsten; Eickhoff, Jan; Klebl, Bert M.; Sundby, Eirik; Hoff, Bard Helge Share Save
An Antiherpesviral Host-Directed Strategy Based on CDK7 Covalently Binding Drugs: Target-Selective, Picomolar-Dose, Cross-Virus Reactivity Yu, DongHoon; Wagner, Sabrina; Schuetz, Martin; Jeon, Yeejin; Seo, Mooyoung; Kim, Jaeseung; Brueckner, Nadine; Kicuntod, Jintawee; Tillmanns, Julia; Wangen, Christina; Hahn, Friedrich; Kaufer, Benedikt B.; Neipel, Frank; Eickhoff, Jan; Klebl, Bert; Nam, Kiyean; Marschall, Manfred Share Save
ComplexEye: a multi-lens array microscope for high-throughput embedded immune cell migration analysis Cibir, Zuelal; Hassel, Jacqueline; Sonneck, Justin; Kowitz, Lennart; Beer, Alexander; Kraus, Andreas; Hallekamp, Gabriel; Rosenkranz, Martin; Raffelberg, Pascal; Olfen, Sven; Smilowski, Kamil; Burkard, Roman; Helfrich, Iris; Tuz, Ali Ata; Singh, Vikramjeet; Ghosh, Susmita; Sickmann, Albert; Klebl, Anne-Kathrin; Eickhoff, Jan Eike; Klebl, Bert; Seidl, Karsten; Chen, Jianxu; Grabmaier, Anton; Viga, Reinhard; Gunzer, Matthias Share Save
Discovery of tetrazolo-pyridazine-based small molecules as inhibitors of MACC1-driven cancer metastasis Yan, Shixian; Schoepe, Paul Curtis; Lewis, Joe; Putzker, Kerstin; Uhrig, Ulrike; Specker, Edgar; von Kries, Jens Peter; Lindemann, Peter; Omran, Anahid; Sanchez-Ibarra, Hector E.; Unger, Anke; Zischinsky, Mia-Lisa; Klebl, Bert; Walther, Wolfgang; Nazare, Marc; Kobelt, Dennis; Stein, Ulrike Share Save
A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation Aarhus, Thomas Ihle; Eickhoff, Jan; Klebl, Bert; Unger, Anke; Boros, Joanna; Choidas, Axel; Zischinsky, Mia -Lisa; Wolowczyk, Camilla; Bjorkoy, Geir; Sundby, Eirik; Hoff, Bard Helge Share Save
Characterization of the Antibacterial Activity of Quinone-Based Compounds Originating from the Alnumycin Biosynthetic Gene Cluster of a Streptomyces Isolate Sagurna, Leonie; Heinrich, Sascha; Kaufmann, Lara-Sophie; Rueckert-Reed, Christian; Busche, Tobias; Wolf, Alexander; Eickhoff, Jan; Klebl, Bert; Kalinowski, Joern; Bandow, Julia E. Share Save
IFNa primes cancer cells for Fusicoccin-induced cell death via 14-3-3 PPI stabilization Andlovic, Blaz; Heilmann, Geronimo; Ninck, Sabrina; Andrei, Sebastian A.; Centorrino, Federica; Higuchi, Yusuke; Kato, Nobuo; Brunsveld, Luc; Arkin, Michelle; Menninger, Sascha; Choidas, Axel; Wolf, Alexander; Klebl, Bert; Kaschani, Farnusch; Kaiser, Markus; Eickhoff, Jan; Ottmann, Christian Share Save
Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form Aarhus, Thomas Ihle; Bjornstad, Frithjof; Wolowczyk, Camilla; Larsen, Kristin Uhlving; Rognstad, Line; Leithaug, Trygve; Unger, Anke; Habenberger, Peter; Wolf, Alexander; Bjorkoy, Geir; Pridans, Clare; Eickhoff, Jan; Klebl, Bert; Hoff, Bard H.; Sundby, Eirik Share Save
A Reinvestigation of the Role of the Sorbic Acid Tail on the Antibacterial and Anti-Tuberculosis Properties of Moiramide B Kollmorgen, Irina; Bachmann, Nathalie; Dal Molin, Michael; Degenhart, Carsten; Zent, Eldar; Pareek, Vikram; Koch, Uwe; Rybniker, Jan; Metzler-Nolte, Nils; Stoll, Raphael; Klebl, Bert; Bandow, Julia Elisabeth; Scherkenbeck, Jurgen Share Save
Assessment of Covalently Binding Warhead Compounds in the Validation of the Cytomegalovirus Nuclear Egress Complex as an Antiviral Target Tillmanns, Julia; Haege, Sigrun; Borst, Eva Maria; Wardin, Julia; Eickhoff, Jan; Klebl, Bert; Wagner, Sabrina; Wangen, Christina; Hahn, Friedrich; Socher, Eileen; Marschall, Manfred Share Save
Novel Tetrazolopyridazine based MACC1 inhibitors are promising for anti-metastatic therapy Shixian, Yan; Schoepe, Paul; Lewis, Joe; Putzker, Kerstin; Uhrig, Ulrike; Specker, Edgar; von Kries, Jens; Sanchez-Ibarra, Hector E.; Unger, Anke; Zischinsky, Mia; Klebl, Bert; Lindemann, Peter; Walther, Wolfgang; Nazare, Marc; Kobelt, Dennis; Stein, Ulrike Share Save
Cyclin-Dependent Kinase 7 Controls mRNA Synthesis by Affecting Stability of Preinitiation Complexes, Leading to Altered Gene Expression, Cell Cycle Progression, and Survival of Tumor Cells Kelso, Timothy W. R.; Baumgart, Karen; Eickhoff, Jan; Albert, Thomas; Antrecht, Claudia; Lemcke, Sarah; Klebl, Bert; Meisterernst, Michael Share Save
Novel tetrazolopyridazine based MACC1 transcriptional inhibitors as promising anti-metastatic therapy Schope, Paul Curtis; Yan, Shixian; Kobelt, Dennis; Lewis, Joe; Putzker, Kerstin; Uhrig, Ulrike; Specker, Edgar; von Kries, Jens Peter; Dahlmann, Mathias; Sanchez-Ibarra, Hector E.; Unger, Anke; Zischinsky, Mia-Lisa; Klebl, Bert; Lindemann, Peter; Walther, Wolfgang; Nazare, Marc; Stein, Ulrike Share Save
A bead-based GPCR phosphorylation immunoassay for high-throughput ligand profiling and GRK inhibitor screening Kaufmann, Johanna; Blum, Nina Kathleen; Nagel, Falko; Schuler, Anna; Drube, Julia; Degenhart, Carsten; Engel, Julian; Eickhoff, Jan Eicke; Dasgupta, Pooja; Fritzwanker, Sebastian; Guastadisegni, Maria; Schulte, Clemens; Miess-Tanneberg, Elke; Maric, Hans Michael; Spetea, Mariana; Kliewer, Andrea; Baumann, Matthias; Klebl, Bert; Reinscheid, Rainer K.; Hoffmann, Carsten; Schulz, Stefan Share Save
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