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Three million images and morphological profiles of cells treated with matched chemical and genetic perturbations Chandrasekaran, Srinivas Niranj; Cimini, Beth A.; Goodale, Amy; Miller, Lisa; Kost-Alimova, Maria; Jamali, Nasim; Doench, John G.; Fritchman, Briana; Skepner, Adam; Melanson, Michelle; Kalinin, Alexandr A.; Arevalo, John; Haghighi, Marzieh; Caicedo, Juan C.; Kuhn, Daniel; Hernandez, Desiree; Berstler, James; Shafqat-Abbasi, Hamdah; Root, David E.; Swalley, Susanne E.; Garg, Sakshi; Singh, Shantanu; Carpenter, Anne E. Share Save
Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler Laber, Samantha; Strobel, Sophie; Mercader, Josep M.; Dashti, Hesam; Santos, Felipe R. C. dos; Kubitz, Phil; Jackson, Maya; Ainbinder, Alina; Honecker, Julius; Agrawal, Saaket; Garborcauskas, Garrett; Stirling, David R.; Leong, Aaron; Figueroa, Katherine; Sinnott-Armstrong, Nasa; Kost-Alimova, Maria; Deodato, Giacomo; Harney, Alycen; Way, Gregory P.; Saadat, Alham; Harken, Sierra; Reibe-Pal, Saskia; Ebert, Hannah; Zhang, Yixin; Calabuig-Navarro, Virtu; Mcgonagle, Elizabeth; Stefek, Adam; Dupuis, Josee; Cimini, Beth A.; Hauner, Hans; Udler, Miriam S.; Carpenter, Anne E.; Florez, Jose C.; Lindgren, Cecilia; Jacobs, Suzanne B. R.; Claussnitzer, Melina Share Save
Optimizing the Cell Painting assay for image-based profiling Cimini, Beth A.; Chandrasekaran, Srinivas Niranj; Kost-Alimova, Maria; Miller, Lisa; Goodale, Amy; Fritchman, Briana; Byrne, Patrick; Garg, Sakshi; Jamali, Nasim; Logan, David J.; Concannon, John B.; Lardeau, Charles-Hugues; Mouchet, Elizabeth; Singh, Shantanu; Abbasi, Hamdah Shafqat; Aspesi, Jr Peter; Boyd, Justin D.; Gilbert, Tamara; Gnutt, David; Hariharan, Santosh; Hernandez, Desiree; Hormel, Gisela; Juhani, Karolina; Melanson, Michelle; Mervin, Lewis H.; Monteverde, Tiziana; Pilling, James E.; Skepner, Adam; Swalley, Susanne E.; Vrcic, Anita; Weisbart, Erin; Williams, Guy; Yu, Shan; Zapiec, Bolek; Carpenter, Anne E. Share Save
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity Wieder, Nicolas; Fried, Juliana Coraor; Kim, Choah; Sidhom, Eriene-Heidi; Brown, Matthew R.; Marshall, Jamie L.; Arevalo, Carlos; Dvela-Levitt, Moran; Kost-Alimova, Maria; Sieber, Jonas; Gabriel, Katlyn R.; Pacheco, Julian; Clish, Clary; Abbasi, Hamdah Shafqat; Singh, Shantanu; Rutter, Justine C.; Therrien, Martine; Yoon, Haejin; Lai, Zon Weng; Baublis, Aaron; Subramanian, Renuka; Devkota, Ranjan; Small, Jonnell; Sreekanth, Vedagopuram; Han, Myeonghoon; Lim, Donghyun; Carpenter, Anne E.; Flannick, Jason; Finucane, Hilary; Haigis, Marcia C.; Claussnitzer, Melina; Sheu, Eric; Stevens, Beth; Wagner, Bridget K.; Choudhary, Amit; Shaw, Jillian L.; Pablo, Juan Lorenzo; Greka, Anna Share Save
Morphology and gene expression profiling provide complementary information for mapping cell state Way, Gregory P.; Natoli, Ted; Adeboye, Adeniyi; Litichevskiy, Lev; Yang, Andrew; Lu, Xiaodong; Caicedo, Juan C.; Cimini, Beth A.; Karhohs, Kyle; Logan, David J.; Rohban, Mohammad H.; Kost-Alimova, Maria; Hartland, Kate; Bornholdt, Michael; Chandrasekaran, Srinivas Niranj; Haghighi, Marzieh; Weisbart, Erin; Singh, Shantanu; Subramanian, Aravind; Carpenter, Anne E. Share Save
Phenotypic Screening for Small Molecules that Protect ?-Cells from Glucolipotoxicity Small, Jonnell C.; Joblin-Mills, Aidan; Carbone, Kaycee; Kost-Alimova, Maria; Ayukawa, Kumiko; Khodier, Carol; Dancik, Vlado; Clemons, Paul A.; Munkacsi, Andrew B.; Wagner, Bridget K. Share Save
High-Throughput Assay to Screen Small Molecules for Their Ability to Prevent Sickling of Red Blood Cells Nakagawa, Akito; Cooper, Marissa K.; Kost-Alimova, Maria; Berstler, James; Yu, Binglan; Berra, Lorenzo; Klings, Elizabeth S.; Huang, Mary S.; Heeney, Matthew M.; Bloch, Donald B.; Zapol, Warren M. Share Save
Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin Wang, Jialiang S.; Kamath, Tushar; Mazur, Courtney M.; Mirzamohammadi, Fatemeh; Rotter, Daniel; Hojo, Hironori; Castro, Christian D.; Tokavanich, Nicha; Patel, Rushi; Govea, Nicolas; Enishi, Tetsuya; Wu, Yunshu; da Silva Martins, Janaina; Bruce, Michael; Brooks, Daniel J.; Bouxsein, Mary L.; Tokarz, Danielle; Lin, Charles P.; Abdul, Abdul; Macosko, Evan Z.; Fiscaletti, Melissa; Munns, Craig F.; Ryder, Pearl; Kost-Alimova, Maria; Byrne, Patrick; Cimini, Beth; Fujiwara, Makoto; Kronenberg, Henry M.; Wein, Marc N. Share Save
Predicting cell health phenotypes using image-based morphology profiling Way, Gregory P.; Kost-Alimova, Maria; Shibue, Tsukasa; Harrington, William F.; Gill, Stanley; Piccioni, Federica; Becker, Tim; Shafqat-Abbasi, Hamdah; Hahn, William C.; Carpenter, Anne E.; Vazquez, Francisca; Singh, Shantanu Share Save
Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease Sidhom, Eriene-Heidi; Kim, Choah; Kost-Alimova, Maria; Ting, May Theng; Keller, Keith; Avila-Pacheco, Julian; Watts, Andrew J. B.; Vernon, Katherine A.; Marshall, Jamie L.; Reyes-Bricio, Estefania; Racette, Matthew; Wieder, Nicolas; Kleiner, Giulio; Grinkevich, Elizabeth J.; Chen, Fei; Weins, Astrid; Clish, Clary B.; Shaw, Jillian L.; Quinzii, Catarina M.; Greka, Anna Share Save
A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury Kost-Alimova, Maria; Sidhom, Eriene-Heidi; Satyam, Abhigyan; Chamberlain, Brian T.; Dvela-Levitt, Moran; Melanson, Michelle; Alper, Seth L.; Santos, Jean; Gutierrez, Juan; Subramanian, Ayshwarya; Byrne, Patrick J.; Grinkevich, Elizabeth; Reyes-Bricio, Estefania; Kim, Choah; Clark, Abbe R.; Watts, Andrew J. B.; Thompson, Rebecca; Marshall, Jamie; Pablo, Juan Lorenzo; Coraor, Juliana; Roignot, Julie; Vernon, Katherine A.; Keller, Keith; Campbell, Alissa; Emani, Maheswarareddy; Racette, Matthew; Bazua-Valenti, Silvana; Padovano, Valeria; Weins, Astrid; McAdoo, Stephen P.; Tam, Frederick W. K.; Ronco, Luciene; Wagner, Florence; Tsokos, George C.; Shaw, Jillian L.; Greka, Anna Share Save
TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41 Carey, Kimberly L.; Paulus, Geraldine L. C.; Wang, Lingfei; Balce, Dale R.; Luo, Jessica W.; Bergman, Phil; Ferder, Ianina C.; Kong, Lingjia; Renaud, Nicole; Singh, Shantanu; Kost-Alimova, Maria; Nyfeler, Beat; Lassen, Kara G.; Virgin, Herbert W.; Xavier, Ramnik J. Share Save
Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation Subramanian, Ayshwarya; Sidhom, Eriene-Heidi; Emani, Maheswarareddy; Vernon, Katherine; Sahakian, Nareh; Zhou, Yiming; Kost-Alimova, Maria; Slyper, Michal; Waldman, Julia; Dionne, Danielle; Nguyen, Lan T.; Weins, Astrid; Marshall, Jamie L.; Rosenblatt-Rosen, Orit; Regev, Aviv; Greka, Anna Share Save
Discovering metabolic disease gene interactions by correlated effects on cellular morphology Jiao, Yang; Ahmed, Umer; Sim, M. F. Michelle; Bejar, Andrea; Zhang, Xiaolan; Talukder, M. Mesbah Uddin; Rice, Robert; Flannick, Jason; Podgornaia, Anna, I; Reilly, Dermot F.; Engreitz, Jesse M.; Kost-Alimova, Maria; Hartland, Kate; Mercader, Josep-Maria; Georges, Sara; Wagh, Vilas; Tadin-Strapps, Marija; Doench, John G.; Edwardson, J. Michael; Rochford, Justin J.; Rosen, Evan D.; Majithia, Amit R. Share Save
Genome-Wide Interrogation of Human Cancers Identifies EGLN1 Dependency in Clear Cell Ovarian Cancers Price, Colles; Gill, Stanley; Ho, Zandra V.; Davidson, Shawn M.; Merkel, Erin; McFarland, James M.; Leung, Lisa; Tang, Andrew; Kost-Alimova, Maria; Tsherniak, Aviad; Jonas, Oliver; Vazquez, Francisca; Hahn, William C. Share Save
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis Zou, Yilong; Palte, Michael J.; Deik, Amy A.; Li, Haoxin; Eaton, John K.; Wang, Wenyu; Tseng, Yuen-Yi; Deasy, Rebecca; Kost-Alimova, Maria; Dancik, Vlado; Leshchiner, Elizaveta S.; Viswanathan, Vasanthi S.; Signoretti, Sabina; Choueiri, Toni K.; Boehm, Jesse S.; Wagner, Bridget K.; Doench, John G.; Clish, Clary B.; Clemons, Paul A.; Schreiber, Stuart L. Share Save
Assignment and ordering of twenty-three unique NotI-linking clones containing expressed genes including the guanosine 5'-monophosphate synthetase gene to human chromosome 3 Fedorova, L; KostAlimova, M; Gizatullin, RZ; Alimov, A; Zabarovska, VI; Szeles, A; Protopopov, AI; Vorobieva, NV; Kashuba, VI; Klein, G; Zelenin, AV; Sheer, D; Zabarovsky, ER Share Save
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